ArticleViewAbstractPharmacognosy Journal,2024,16,5,998-1003.DOI:10.5530/pj.2024.16.161Published:October 2024Type:Original ArticleJuglans regia L.: Source of Bioactive Compounds with Potential Anticancer ActivityCarla Y. Requejo-Rodríguez, Elmer M. Roncal-Alayo, Carmen R. Silva-Correa, Víctor E. Villarreal-La Torre, William A. Sagástegui-Guarniz, William A. Sagástegui-Guarniz, Walter E. Janampa-Castillo, José E. Alvarez- Trujillo, Glenda J. Vela-Urbina, Abhel A. Calderón-Peña, Cinthya L. Aspajo-Villalaz, María E. Cotrina-León, Julio A. Castañeda-Carranza, and Deivy Y. Dionicio-Rosado Carla Y. Requejo-Rodríguez¹, Elmer M. Roncal-Alayo¹, Carmen R. Silva-Correa2,*, Víctor E. Villarreal-La Torre2, William A. Sagástegui-Guarniz2, César D. Gamarra-Sánchez2, Walter E. Janampa-Castillo3, José E. Alvarez-Trujillo3, Glenda J. Vela-Urbina3, Abhel A. Calderón- Peña4, Cinthya L. Aspajo- Villalaz4, María E. Cotrina-León5, Julio A. Castañeda-Carranza5, Deivy Y. Dionicio-Rosado6 1Escuela de Posgrado, Universidad Nacional de Trujillo, Perú 2Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo, Perú 3Facultad de Educación y Ciencias de la Comunicación, Universidad Nacional de Trujillo, Perú 4Facultad de Ciencias Biológicas, Universidad Nacional de Trujillo, Perú. 5Facultad de Ciencias Físicas y Matemáticas, Universidad Nacional de Trujillo, Perú. 6Facultad de Ciencias Sociales y Humanidades, Universidad Nacional Ciro Alegría, Perú Abstract:Background: Juglans regia L., commonly known as “walnut”, belongs to the Juglandaceae family, with antioxidant, anti-inflammatory, and hypoglycemic medicinal properties. Objective: Describe the anticancer potential of the bioactive compounds present in Juglans regia L. Method: Recent scientific studies were reviewed on the effects of bioactive compounds from Juglans regia L. on inhibiting tumor growth and cancer development in several experimental models. To do this, a scientific literature search was carried out, using databases such as PubMed, Scopus, and Science Direct. Results: Regarding the selected articles, it was found that some bioactive compounds from Juglans regia L. exhibit mechanisms of anticancer action, among which the following stand out: induction of apoptosis, suppression of angiogenesis, and modulation of cell signaling pathways related to cell proliferation and survival. Conclusion: It is concluded that Juglans regia L. contains active metabolites with potential anticancer effects. Keywords:Angiogenesis, Antitumor, Apoptosis, Cancer, Juglans regia L.View:PDF (363.07 KB) PDF Images Compuestos Bioactivos de Juglans regia L. ‹ Pharmacognosy Journal Vol 16, Issue 5, Sep-Oct, 2024 up Study of Profile of the Government Programs Implementation Germas and Traditional Medicine between Two Generations in a Rural Area ›