Phytochemical Profile and Bioactivity of Dioscorea transversa R. Br: Antioxidant and Anti-Inflammatory Potential of Leaf and Tuber

Various species of Dioscorea, commonly referred to as wild yams, are employed as food and used globally for medicinal purposes. Dioscorea transversa, also known as the long or pencil yam, is a native to northern and eastern Australia and is also found in the open forests of southern India. The tubers of this plant are consumed by local tribes in northern Kerala during times of famine, and they are believed to enhance bone and muscle strength. Furthermore, it is incorporated with other ingredients in their traditional postnatal rejuvenation preparations. However, this plant which is infrequently examined for its biochemical impacts on humans. This research aimed to identify the phytochemicals present in the tuber and leaf of Dioscorea transversa and to assess solvent extracts for their antioxidant and anti-inflammatory properties. The leaf sample demonstrated a notable concentration of phenolic compounds, tannins, flavonoids, and terpenoids, while the tuber was rich in saponins, proteins, and steroids. It was noted that the aqueous methanolic extract of the leaves (AqML) exhibited superior antioxidant and anti-inflammatory activity in comparison to the other five extracts explored. This study underscores D. transversa as a significant source of natural bioactive compounds and advocates for further research to delve deeper into the pharmacological potential of this plant