Nano Transdermal Delivery Potential of Fucoidan from Sargassum sp. (Brown Algae) as Chemoprevention Agent for Breast Cancer Treatment

Syeftyan Muhammad Ali Hamami¹, Michelle Fai¹, Ahmad Fariduddin Aththar¹, M Nizam Zulfi Zakaria¹, Viol Dhea Kharisma^2,3, Ahmad Affan Ali Murtadlo³, Muhammad Badrut Tamam⁴, Vikash Jakhmola⁵, Muhammad Hermawan Widyananda^1,3, Dora Dayu Rahma Turista⁶, Maksim Rebezov^7,8,9, Nikolai Maksimiuk¹⁰, Nataliya Kulmakova¹¹, Evgeniya Latynina¹¹, ANM Ansori¹², Rahadian Zainul^13,14,*, Riso Sari Mandeli ¹⁵, Devi Purnamasari¹⁶, Oski Illiandri¹⁷, Khoirun Nisyak¹⁸, Ernarisa Fitri¹⁹

¹Department of Biology, Faculty of Mathematics and Life Sciences, Universitas Brawijaya, Malang, INDONESIA.

²Department of Biology, Faculty of Science and Technology, Universitas Airlangga, Surabaya, INDONESIA.

³Division of Molecular Biology and Genetics, Generasi Biology Indonesia Foundation, Gresik, INDONESIA.

⁴Department of Biology, Faculty of Sciences and Technology, Universitas Muhammadiyah Lamongan, Lamongan, INDONESIA.

⁵Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun, INDIA.

⁶Department of Biology Education, Faculty of Teacher Training and Education, Mulawarman University, Samarinda, INDONESIA.

⁷Department of Scientific Research, V. M. Gorbatov Federal Research Center for Food Systems, Moscow, RUSSIAN FEDERATION.

⁸Faculty of Biotechnology and Food Engineering, Ural State Agrarian University, Yekaterinburg, RUSSIAN FEDERATION.

⁹Department of Scientific Research, Russian State Agrarian University Moscow Timiryazev Agricultural Academy, Moscow, RUSSIAN FEDERATION.

¹⁰Institute of Medical Education, Yaroslav-the-Wise Novgorod State University, Velikiy Novgorod, RUSSIAN FEDERATION.

¹¹Department of Veterinary Medicine, Russian State Agrarian University - Moscow Timiryazev Agricultural Academy, Moscow, RUSSIAN FEDERATION.

¹²Professor Nidom Foundation, Surabaya, INDONESIA.

¹³Center for Advanced Material Processing, Artificial Intelligence, and Biophysic Informatics (CAMP-BIOTICS), Universitas Negeri Padang, Padang, INDONESIA.

¹⁴Department of Chemistry, Faculty of Mathematics and Natural Sciences Universitas Negeri Padang, Padang, INDONESIA.

¹⁵Environmental Science, Postgraduate Programme, Universitas Negeri Padang, INDONESIA

¹⁶Department of Radiology Engineering, Universitas Awal Bros, Pekanbaru, INDONESIA

¹⁷Department of Biomedicine, School of Medicine, Lambung Mangkurat University, Banjarmasin, Indonesia

¹⁸Department of Pharmacy, Faculty of Public Health, Universitas Anwar Medika, Sidoarjo, INDONESIA

¹⁹Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Andalas, Padang, INDONESIA