Integration of Analytical and Computational Techniques for Bioactive Profiling of Celtis timorensis Span Bark

A wound occurs when there is damage to the body's tissue due to a puncture in the skin¹. An injury is caused by a breakdown in the skin's barrier function, resulting in either a superficial or deep wound². The healing process is complicated by chronic wounds, but acute wounds might go through the normal sequential stages of wound healing³. Particularly in hyperglycemic circumstances, chronic wound healing is hindered and imprisoned, usually during the inflammatory phase⁴. The wound's healing process stagnates and takes longer than expected. Chronic wounds are persistent because of a number of pathological factors, including poor blood circulation and bacterial infections in the wounds. These include diabetes mellitus and other chronic disorders⁵.