ArticleViewAbstractPharmacognosy Journal,2025,17,3,365-369.DOI:10.5530/pj.2025.17.45Published:June 2025Type:Research ArticleAntimicrobial and Antioxidant Activities of Phanera aureifolia (K.Larsen & S.S.Larsen) Bandyop., P.P.Ghoshal & M.K.Pathak Leaf Ethanolic ExtractsGornganok Piboonpol, On-Anong Somsap, Wanita Panthong, Penporn Sujiwattanarat, and Anussara Kamnate Gornganok Piboonpol 1*, On-anong Somsap2, Wanita Panthong2, Penporn Sujiwattanarat2, Anussara Kamnate3 1Department of Pharmacology, Faculty of medicine, Princess of Naradhiwas University, Narathiwat, Thailand 2Department of Biochemistry, Faculty of medicine, Princess of Naradhiwas University, Narathiwat, Thailand 3Department of Anatomy, Faculty of medicine, Princess of Naradhiwas University, Narathiwat, Thailand Abstract:Introduction: Natural antioxidants and antimicrobial agents are abundantly found in medicinal plants. Objective: This study evaluated the antimicrobial and antioxidant activities of two colors from Phanera aureifolia (K.Larsen & S.S.Larsen) Bandyop., P.P.Ghoshal & M.K.Pathak leaf ethanolic extracts including gold and green leaves. Method: To assess antimicrobial efficacy, the agar well diffusion technique was analyzed. Scanning electron microscopy (SEM) was utilized to investigate the ultrastructural alterations in MRSA caused by leaf extracts. DPPH assay was used to assess antioxidant activity. The total amounts of phenolic compounds and flavonoids were evaluated through the Folin-Ciocalteu and aluminum chloride colorimetric techniques, respectively. The statistical analysis using an independent t-test. Results: Both extracts demonstrated activity against Pseudomonas aeruginosa TISTR146, Micrococcus luteus TISTR884, Staphylococcus aureus TISTR517 and Methicillin-resistant S. aureus 142 (MRSA142). Their activity against M. luteus TISTR884 was the highest observed. The MIC of both extracts against MRSA were 10 mg/ml. SEM analysis revealed that the cells exhibited noticeable enlargement and swelling compared to untreated MRSA cells. Extract from the green leaves of Gold leaf Bauhinia showed greater radical scavenging activity, higher total phenolic and flavonoid contents, compared to those from the golden leaves. Conclusions: The findings show that the extract from the green leaves of Gold leaf Bauhinia possess higher antioxidant potential compared to those from the golden leaves. In addition, both extracts exhibited antimicrobial activity, especially against MRSA. Keywords:Antimicrobial activity, Antioxidant, Flavonoid compound, P.P.Ghoshal & M.K.Pathak, Phanera aureifolia (K.Larsen & S.S.Larsen) Bandyop., Phenolic compoundView:PDF (302.52 KB) PDF Images Scanning electron micrographs of untreated MRSA142 (A) and treated MRSA142 with green leaves (B) and golden leaves of Gold leaf Bauhinia (C). Magnification of x 30000. ‹ How Extensively is Herbal Medicine Used as a Therapy for Insomnia? A Bibliometric Study up Formulation Strategy and Excipient Selection for Tribulus terrestris L. Tablets: A Quality-Based Approach ›