<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hesti Riasari</style></author><author><style face="normal" font="default" size="100%">Sani Nurlaela Fitriansyah</style></author><author><style face="normal" font="default" size="100%">Siti Uswatun Hasanah</style></author><author><style face="normal" font="default" size="100%">Mia Aulia</style></author><author><style face="normal" font="default" size="100%">Khania Zavella</style></author><author><style face="normal" font="default" size="100%">Nurul Padilah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantification of Phenolics, Flavonoids, and In Vitro Antioxidant Activity in Rosella and Breadfruit Leaf Extracts</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Flavonoids</style></keyword><keyword><style  face="normal" font="default" size="100%">Quantification of Phenolics</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">688-698</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Indonesia is a country rich in biodiversity, with numerous plant species traditionally used in medicine. One such plant is breadfruit (&lt;em&gt;Artocarpus altilis&lt;/em&gt;), whose leaves contain bioactive compounds such as flavonoids, saponins, tannins, quercetin, artocarpanone, and artoindonesianin. Another plant with high medicinal value is roselle (&lt;em&gt;Hibiscus sabdariffa L.&lt;/em&gt;), a tropical plant from the Malvaceae family known for its rich phenolic content. Both plants are widely found across Indonesia and have potential as natural antioxidants. In this study, the dry extracts were prepared using the decoction method followed by spray drying. Phytochemical screening, total phenolic and flavonoid content analysis, and antioxidant activity tests were performed using standard in vitro methods. The DE2C extract (a combination of breadfruit leaves and roselle flowers) exhibited high total phenol content at 0.953 ± 0.005 g GAE/100 g and flavonoid content at 136.97 ± 5.050 μg QE/100 g. Meanwhile, the DE3C extract showed an IC&lt;sub&gt;₅₀&lt;/sub&gt; value of 540.55 ppm in the DPPH assay. Pearson correlation analysis showed a strong positive correlation between total phenolic content and antioxidant activity (R = 0.956, p &amp;lt; 0.05), while flavonoids also showed a moderate correlation (R = 0.502, p &amp;lt; 0.05). These results confirm that phenolic compounds play a key role in the antioxidant potential of the extract.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">688</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Hesti Riasari&lt;sup&gt;1,*&lt;/sup&gt;, Sani Nurlaela Fitriansyah&lt;sup&gt;1&lt;/sup&gt;, Siti Uswatun Hasanah&lt;sup&gt;1&lt;/sup&gt;, Mia Aulia&lt;sup&gt;1&lt;/sup&gt;, Khania Zavella&lt;sup&gt;1&lt;/sup&gt;, Nurul Padilah&lt;sup&gt;1&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Departement of Pharmaceutical Biology, Indonesia School of Pharmacy, Bandung. INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Novi Fajar Utami</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Hayun Hayun</style></author><author><style face="normal" font="default" size="100%">Kusmardi Kusmardi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantification of Active Compounds from Coffea canephora Pierre ex A.Froehner cascara and their Potential Against MCF-7 and HeLa</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Breast cancer</style></keyword><keyword><style  face="normal" font="default" size="100%">Cascara</style></keyword><keyword><style  face="normal" font="default" size="100%">Coffea canephora</style></keyword><keyword><style  face="normal" font="default" size="100%">Cytotoxic</style></keyword><keyword><style  face="normal" font="default" size="100%">Isolation</style></keyword><keyword><style  face="normal" font="default" size="100%">servical cancer</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">509-518</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;The utilization of coffee cascara, a byproduct of coffee cultivation, in cancer therapy research. This research begins with the rationale of exploring medicinal plants, especially coffee, to obtain compounds that can target cancer cells with fewer side effects. &lt;strong&gt;Objectivity: &lt;/strong&gt;This research aims to extract and evaluate the secondary metabolites from robusta coffee cascara, such as friedelin, lupeol, stigmasterol, ursolic acid, caffeine, chlorogenic acid, caffeic acid, and catechin, for their cytotoxic activity against Hela and MCF-7 cells. The aim of this research is also to identify and understand the cytotoxic mechanisms of compounds like stigmasterol, which showed significant cytotoxicity against cancer cells, paving the way for developing targeted cancer therapies from natural sources. &lt;strong&gt;Methods:&lt;/strong&gt; Robusta coffee cascara then goes to the process of extraction using ethanol, fractionation, isolation, purification, and characterization, followed by bioactivity evaluation using in vitro method through breast cancer cell line MCF-7 and cervical cancer cell line HeLa and determination of active compound levels. &lt;strong&gt;Results:&lt;/strong&gt; The cascara, a byproduct of coffee cultivation, is rich in proteins, polysaccharides, and bioactive compounds. Through extraction and purification processes, eight compounds were isolated and characterized, including &lt;strong&gt;(1)&lt;/strong&gt; friedelin, &lt;strong&gt;(2)&lt;/strong&gt; lupeol,&lt;strong&gt; (3)&lt;/strong&gt; Stigmasterol, &lt;strong&gt;(4)&lt;/strong&gt; Ursolic acid, &lt;strong&gt;(5)&lt;/strong&gt; caffeine, &lt;strong&gt;(6)&lt;/strong&gt; Chlorogenic acid, &lt;strong&gt;(7)&lt;/strong&gt; caffeic acid, and &lt;strong&gt;(8)&lt;/strong&gt; catechin. Bioactivity evaluation shows that stigmasterol (3) is the most cytotoxic compound with a value against Hela cells with an IC50 value of 25.85 μg/mL in the toxic category and against MCF-7 cells with an IC50 value of 12.83 μg/mL in the very toxic category. The results of determining the levels of active compounds in robusta coffee cascara extract showed that friedelin &lt;strong&gt;(1)&lt;/strong&gt; 0.539±0.137%; lupeol &lt;strong&gt;(2)&lt;/strong&gt; levels were 0.087±0.015%; &lt;strong&gt;(3)&lt;/strong&gt; stigmasterol 0.126±0.046%; ursolic acid &lt;strong&gt;(4)&lt;/strong&gt; 0.627±0.002%; caffeine &lt;strong&gt;(5) &lt;/strong&gt;3,203±0.069%; chlorogenic acid &lt;strong&gt;(6)&lt;/strong&gt; 0.679±0.003%; caffeic acid &lt;strong&gt;(7) &lt;/strong&gt;0.153±0.003% and catechin &lt;strong&gt;(8)&lt;/strong&gt; 0.3590.012% mg/g extract. &lt;strong&gt;Conclusion:&lt;/strong&gt; The research on robusta coffee cascara extract as a potential source of anticancer compounds.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">509</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Novi Fajar Utami&lt;sup&gt;1,2&lt;/sup&gt;, Berna Elya&lt;sup&gt;1&lt;/sup&gt;*, Hayun Hayun&lt;sup&gt;3&lt;/sup&gt;, Kusmardi Kusmardi&lt;sup&gt;4,5,6&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Phytochemistry and Pharmacognosy, Faculty of Pharmacy, Universitas Indonesia, Depok 16424 West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Math and Science, Universitas Pakuan, Jl. Raya Pakuan 1 Bogor, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Faculty of Pharmacy, Universitas Indonesia, Depok 16424 West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Anatomic Pathology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, 10430, Jakarta, Indonesia, 10430 INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Drug Development Research Cluster, Indonesia Medical Educational and Research Institute, Jl. Salemba Raya No.6, Jakarta 10340, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Human Cancer Research Cluster, Indonesia Medical Educational and Research Institute, Jl. Salemba Raya No.6, Jakarta 10340, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Diah Dhianawaty</style></author><author><style face="normal" font="default" size="100%">Resti Gradia Dwiwina</style></author><author><style face="normal" font="default" size="100%">Wulan Mayasari</style></author><author><style face="normal" font="default" size="100%">Achadiyani</style></author><author><style face="normal" font="default" size="100%">Ruslin</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantification of Four Phytochemical Parameters of Imperata cylindrica Leaves to Promote Its Use as A Medicinal Plant</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Imperata cylindrica leaves</style></keyword><keyword><style  face="normal" font="default" size="100%">total flavonoid content</style></keyword><keyword><style  face="normal" font="default" size="100%">total phenolic content</style></keyword><keyword><style  face="normal" font="default" size="100%">Total Tannin content</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">108-117</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; The benefits of Imperata cylindrica (I. cylindrica) leaves and their relationship to the content of phytochemical compounds have been widely studied. The aim of this study was to promote I. cylindrica leaves from Kertajati Subdistrict in Majalengka Regency in their use as a medicinal plant based on the four parameters, namely the content of total phenolic content, total flavonoid content, total tannin content, and antioxidant activity. The four parameters that become the basis for the benefits of the leaves were compared with the four parameters of the roots. &lt;strong&gt;Methods:&lt;/strong&gt; Quantification of total phenolic content, total flavonoid content, total tannin content, and antioxidant activity used Folin-Ciocalteu, aluminium chloride, Fe(III) chloride and 1.10-Phenanthroline, and 1,1-diphenyl-2-pikrilhidrazil (DPPH) methods, respectively. All methods used visible spectrophotometric method. &lt;strong&gt;Results: &lt;/strong&gt;The percentages of total phenolic content, total flavonoid content, total tannin content, and IC50 of antioxidant activity of I. cylindrica leaves extract were 9% (GAE), 2.1% (QE), 5.6% (TAE), and 100.5 ppm, respectively. Then, the percentages of I. cylindrica roots extract showed the percentages of total phenolic content, total flavonoid content, total tannin content, and IC50 of antioxidant activity were 5.8% (GAE), 0.64% (QE), 3% (TAE), and 241 ppm, respectively.&lt;strong&gt; Conclusion:&lt;/strong&gt; The extract of I. cylindrica leaves contained the phenolic compound, namely flavonoids, tannins and other phenolic compounds, and had antioxidant activity. All parameters have been reported to have positive effect on health. Therefore, the leaves of I. cylindrica from Kertajati Subdistrict are discovered to have effects on health which are suitable to be promoted as a medicinal plant.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">108</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Diah Dhianawaty&lt;sup&gt;1&lt;/sup&gt;*, Resti Gradia Dwiwina&lt;sup&gt;1&lt;/sup&gt;, Wulan Mayasari&lt;sup&gt;1&lt;/sup&gt;, Achadiyani1, Ruslin&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Pharmacy, Halu Oleo University, Kendari, Southeast Sulawesi, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Lalu Muhammad Saleh</style></author><author><style face="normal" font="default" size="100%">Syamsiar S. Russeng</style></author><author><style face="normal" font="default" size="100%">Istiana Tadjuddin</style></author><author><style face="normal" font="default" size="100%">Iva Hardi Yanti</style></author><author><style face="normal" font="default" size="100%">Nurul Mawaddah Syafitri</style></author><author><style face="normal" font="default" size="100%">Yulianah Rahmadani</style></author><author><style face="normal" font="default" size="100%">Mahfuddin Yusbud</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Quasi-Experimental One Group Pre-Post Test Design in Air Traffic Controller in Indonesia: Progressive Muscle Relaxation</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">638-643</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objectives:&lt;/strong&gt; The effectiveness of progressive muscle relaxation (PMR) in assessing the general health of air traffic controllers (ATC) is still insufficient, specifically when examining the psychological conditions of workers who use questionnaire instruments. Therefore, this research aimed to evaluate the use of PMR program in ATC by developing a model using biomarkers (saliva) tested on the cocorometer stress diagnostic tool and validity, including observing related determinants in the work environment. &lt;strong&gt;Methods:&lt;/strong&gt; A quasi-experimental method was used, focusing on one group pre-post-test design for 92 respondents across six research areas in Indonesia. All respondents had received training in PMR methods conducted by psychologists. Subsequently, ongoing assistance was provided in implementing relaxation by a trained reminder team for eight weeks to maintain the precision and effectiveness of the intervention. Further analysis was conducted using the Wilcoxon signed rank test to evaluate the success of the intervention. &lt;strong&gt;Results:&lt;/strong&gt; The implementation of PMR program in ATC reduced the incidence of stress levels after the observation. Statistically, the feeling of fatigue was a significant variable that decreased in mean value after the implementation of the relaxation program on the data review. The main benefit of PMR program in improving psychological health conditions (stress) was found in Surabaya branch ATC. &lt;strong&gt;Conclusions: &lt;/strong&gt;The relaxation program was proven to reduce stress levels in ATC, showing an improvement in conditions before and after the implementation of PMR.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">638</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Lalu Muhammad Saleh&lt;sup&gt;1&lt;/sup&gt;*, Syamsiar S. Russeng&lt;sup&gt;1&lt;/sup&gt;, Istiana Tadjuddin&lt;sup&gt;2&lt;/sup&gt;, Iva Hardi Yanti&lt;sup&gt;3&lt;/sup&gt;, Nurul Mawaddah Syafitri&lt;sup&gt;1&lt;/sup&gt;, Yulianah Rahmadani&lt;sup&gt;1&lt;/sup&gt;, Mahfuddin Yusbud&lt;sup&gt;1&lt;/sup&gt;, Anwar Mallongi&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Occupational Health and Safety, Faculty of Public Health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Psychology, Faculty of Medicine, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Epidemiological, Faculty of Public Health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Meilla Dwi Andrestian</style></author><author><style face="normal" font="default" size="100%">Meitria Syahadatina Noor</style></author><author><style face="normal" font="default" size="100%">Resa Ana Dina</style></author><author><style face="normal" font="default" size="100%">Ayunina Rizky Ferdina</style></author><author><style face="normal" font="default" size="100%">Zulfiana Dewi</style></author><author><style face="normal" font="default" size="100%">Niken Widyastuti Hariati</style></author><author><style face="normal" font="default" size="100%">Purnawati Hustina Rachman</style></author><author><style face="normal" font="default" size="100%">Muhammad Irwan Setiawan</style></author><author><style face="normal" font="default" size="100%">Windy Tri Yuana</style></author><author><style face="normal" font="default" size="100%">Ali Khomsan</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Qualitative Study on Adolescent Marriage and The Risk of  Stunting in South Kalimantan</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adolescent marriage</style></keyword><keyword><style  face="normal" font="default" size="100%">Qualitative investigation</style></keyword><keyword><style  face="normal" font="default" size="100%">Stunting</style></keyword><keyword><style  face="normal" font="default" size="100%">Toddler feeding pattern</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">1016-1023</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; An exploratory qualitative investigation to determine the causes of adolescent marriage, analyze the effect of early marriage on stunting, and analyze the food patterns of toddlers in adolescent marriage in South Kalimantan, Indonesia.&lt;strong&gt; Method:&lt;/strong&gt; The method used is phenomenology using the FGD system and in-depth interviews. Participants include the FGD informants from the Family Planning Regional Apparatus Organization, the Office of Women's Empowerment and Child Protection and the Office of Religious Affairs from 13 Regencies/ Cities in South Kalimantan. In-depth interview informants were adolescent marriage offenders and their parents, adolescent pregnant women, midwives, integrated health service post cadres, and community leaders each taken from three Regencies/ Cities. &lt;strong&gt;Results: &lt;/strong&gt;There are not many formal adolescent marriages because they have to get a recommendation from the Religious Courts. Adolescent marriages mostly occur through informal marriages. The high rate of early marriage in South Kalimantan Province is caused by culture and weak enforcement of the rules. The incidence of adolescent marriage is caused by promiscuity and information. Meanwhile, adolescent marriage is mostly due to economic motives and limited education facilities in rural areas. Adolescent marriage is not closely related to the incidence of stunting, but low education can be a factor in the inability of parents to provide good parenting, especially feeding pratice. &lt;strong&gt;Conclusions:&lt;/strong&gt; Adolescent marriages appear to be triggered by economic motives and teenagers' desires, as well as driven by economic conditions, social influences, and a lack of encouragement to complete formal education. It was observed that stunting is more common among toddlers with adolescent mothers than toddlers with adult mothers. There is a poor feeding parenting pattern of toddlers with adolescent parents.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1016</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Meilla Dwi Andrestian&lt;sup&gt;1,&lt;/sup&gt;*, Meitria Syahadatina Noor&lt;sup&gt;2&lt;/sup&gt; , Resa Ana Dina&lt;sup&gt;3&lt;/sup&gt; , Ayunina Rizky Ferdina&lt;sup&gt;4&lt;/sup&gt; , Zulfiana Dewi&lt;sup&gt;5&lt;/sup&gt; , Niken Widyastuti Hariati&lt;sup&gt;6&lt;/sup&gt; , Purnawati Hustina Rachman&lt;sup&gt;7&lt;/sup&gt; , Muhammad Irwan Setiawan&lt;sup&gt;8&lt;/sup&gt; , Windy Tri Yuana&lt;sup&gt;9&lt;/sup&gt; , Ali Khomsan&lt;sup&gt;10&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Nutrition, Polytechnic of Health Ministry of Health, Banjarbaru, South Kalimantan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Medicine, University of Lambung Mangkurat, Banjarmasin, South Kalimantan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Community Nutrition, Faculty of Human Ecology, IPB University, Bogor, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;National Research and Innovation Agency, Bogor, West Jawa, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Nutrition, Polytechnic of Health Ministry of Health, Banjarbaru, South Kalimantan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Nutrition, Polytechnic of Health Ministry of Health, Banjarbaru, South Kalimantan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Department of Community Nutrition, Faculty of Human Ecology, IPB University, Bogor, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;8&lt;/sup&gt;Faculty of Medicine, University of Lambung Mangkurat, Banjarmasin, South Kalimantan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;9&lt;/sup&gt;National Research and Innovation Agency, Bogor, West Jawa, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;10&lt;/sup&gt;Department of Community Nutrition, Faculty of Human Ecology, IPB University, Bogor, West Java, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sohordinatus Ifan Unkelefta</style></author><author><style face="normal" font="default" size="100%">Amran Razak</style></author><author><style face="normal" font="default" size="100%">Sukri Palutturi</style></author><author><style face="normal" font="default" size="100%">Balqis</style></author><author><style face="normal" font="default" size="100%">Aminuddin Syam</style></author><author><style face="normal" font="default" size="100%">Andi Ummu Salmah</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quality of Health Services of Non-Accredited Health Centers on Patient Satisfaction</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Health</style></keyword><keyword><style  face="normal" font="default" size="100%">Patient.</style></keyword><keyword><style  face="normal" font="default" size="100%">Quality</style></keyword><keyword><style  face="normal" font="default" size="100%">Satisfaction</style></keyword><keyword><style  face="normal" font="default" size="100%">Service</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">633-640</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Health Centre a health service facility that organizes public health efforts and first-level individual health efforts, by prioritizing promotive and preventive efforts in its working area. Health Center as a first-level health facility is required to always improve service quality and patient safety, improve health center performance, protect health human resources, the community and the environment. The purpose of this study was to explore or describe the quality of health services on patient satisfaction at the Tiakur Health Center, Southwest Maluku Regency. &lt;strong&gt;Methods: &lt;/strong&gt;This research is a type of qualitative research with a descriptive phenomenological approach. Key informants in this study were patients who had undergone treatment at the Tiakur Health Center from January to December 2022 and supporting informants were the head of the health services facility field, the head of the Tiakur Health Center, the head of Tiakur administration and the head of the Tiakur Health Center working group. The technique of determining informants using purposive sampling method. The instruments used were in-depth interview guidelines and focus group discussions. &lt;strong&gt;Results&lt;/strong&gt;: The results showed that the dimensions of service quality, namely effective, efficient, patient-focused and safe, have not been fulfilled properly while the dimensions of accessible and fair have been fulfilled properly. The Tiakur Health Center needs to make improvements to health services so that service quality and patient satisfaction can be realized properly. &lt;strong&gt;Conclusion:&lt;/strong&gt; This qualitative study of patient satisfaction with non-accredited Health Center as health services can be used as evaluation material to be able to improve and improve the health services of Tiakur Health Center to the community.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">633</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sohordinatus Ifan Unkelefta*, Amran Razak, Sukri Palutturi, Balqis, Aminuddin Syam, Andi Ummu Salmah, Anwar Mallongi&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Faculty of Public Health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Marisca Evalina Gondokesumo</style></author><author><style face="normal" font="default" size="100%">Silmi Qurrotu Aini</style></author><author><style face="normal" font="default" size="100%">Siti Rahmadani</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantitative Analysist of Ethnomedicinal Practice and Used by the Banceuy Tribe in Subang Village of Indonesia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Banceuy tribe</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant part use</style></keyword><keyword><style  face="normal" font="default" size="100%">Species and family use value</style></keyword><keyword><style  face="normal" font="default" size="100%">Traditional medicine treatment</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">655-667</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background&lt;/strong&gt;: The people of Banceuy, Indonesia have used plants for traditional medicine treatment for generation to generation. However, this local knowledge has not been recorded until today. The quantitative approach of ethnomedicinal documented show the usefulness of plant. More application medicinal plant, more pharmacological reported, more drug discovery potential development. This study aims to understanding the utilization of plants for medicinal treatment by the people of Banceuy tribe, Subang village, Indonesia. &lt;strong&gt;Methods: &lt;/strong&gt;We conducted semi-structured interviews with a total of 35 informants that representative 10% of the total family units in Banceuy. The data has been analysed within species use value (SUV), family use value (FUV), plant part use (PPU), and the relative frequency of citation that was calculated based on fidelity level (FL). &lt;strong&gt;Result:&lt;/strong&gt; We found 91 identified species and 3 unidentified species belonging of 41 group of families to treat 26 types of diseases. Among the recorded, Zingiberaceae and Piperaceae were the most abundant. The plant specieses with the highest SUV were &lt;em&gt;Abelmoschus manihot&lt;/em&gt; (L.) Medik. (0.74) and &lt;em&gt;Ageratum conyzoides&lt;/em&gt; L. (0.71). The leaves were found as the most used plant part and decoction was the dominant plants in medicinal administration. There were several unique traditional medicine treatments in Banceuy, such as tuak for cough ailment and post-partum treatment by mixed leaves concoction. Finally, all the data documented would be importance for new drug discovery, dried herbal market, as well as improving the society local income.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">655</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Marisca Evalina Gondokesumo&lt;sup&gt;1,*&lt;/sup&gt;, Silmi Qurrotu Aini&lt;sup&gt;2&lt;/sup&gt;, Siti Rahmadani&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, University of Surabaya, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biology, Indonesia University of Education, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Raden Anita Indriyanti</style></author><author><style face="normal" font="default" size="100%">Eko Fuji Ariyanto</style></author><author><style face="normal" font="default" size="100%">Hermin Aminah Usman</style></author><author><style face="normal" font="default" size="100%">Ristaniah Rose Effendy</style></author><author><style face="normal" font="default" size="100%">Diah Dhianawaty</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantification of total polyphenols and flavonoids, antioxidant activity, and Sinensetin and Imperatorin contents of Imperata cylindrica root ethanol extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoid</style></keyword><keyword><style  face="normal" font="default" size="100%">Imperata cylindrica</style></keyword><keyword><style  face="normal" font="default" size="100%">Polyphenol</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">327-337</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt;&lt;em&gt;&lt;strong&gt; &lt;/strong&gt;Imperata cylindrica&lt;/em&gt;, commonly known as cogon grass, is currently widely distributed and used as a medicinal plant. The major compounds that have been isolated and identified are polyphenols and flavonoids, which have many biological activities such as antioxidant, and anticancer. Polyphenols and flavonoids are mostly found in the roots and leaves. This study aimed to perform phytochemical screening on &lt;em&gt;I. cylindrica&lt;/em&gt; root ethanol extract from Sragen, Central Java, Indonesia and determine the total polyphenol, flavonoid, antioxidant activity and quantify Sinensetin and Imperatorin contents of the extract.&lt;strong&gt; Method:&lt;/strong&gt; Quantification of all parameters were measured using visible spectrophotometric methods. Total polyphenol, total flavonoid contents, as well as antioxidant activity were measured using Folin-Ciocalteu reagent, aluminum chloride reagent, and 1,1-diphenyl-2-picrylhydrazyl, respectively, and quantification of Sinensetin and Imperatorin were measured using High Performance Liquid Chromatography. &lt;strong&gt;Results:&lt;/strong&gt;&lt;em&gt; I cylindrica&lt;/em&gt; root ethanol extract had a total polyphenol content of 1.109% gallic acid equivalent, total flavonoid content of 0.1% quercetin equivalent, and antioxidant activity IC&lt;sub&gt;50&lt;/sub&gt; 824.30 μg/ml. Sinensetin and Imperatorin were also identified in Fractions 1 to 11 with concentrations of 0.0157 and 0.0178 mg/kg extract, respectively. &lt;strong&gt;Conclusion:&lt;/strong&gt; &lt;em&gt;I. cylindrica &lt;/em&gt;root ethanol extract from Sragen had active phytochemical compounds of polyphenols, flavonoids, and antioxidants as well as Sinensetin and Imperatorin.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><accession-num><style face="normal" font="default" size="100%">11</style></accession-num><section><style face="normal" font="default" size="100%">327</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Raden Anita Indriyanti&lt;sup&gt;1,2*&lt;/sup&gt;, Eko Fuji Ariyanto&lt;sup&gt;3&lt;/sup&gt;, Hermin Aminah Usman&lt;sup&gt;4&lt;/sup&gt;, Ristaniah Rose Effendy&lt;sup&gt;5&lt;/sup&gt;, Diah Dhianawaty&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, Faculty of Medicine, Bandung Islamic University, Bandung, West Java, Indonesia&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Doctoral Program in Medical Science, Faculty of Medicine, Padjadjaran University, Bandung, West Java, Indonesia&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Biomedical Sciences, Division of Biochemistry and Molecular Biology, Faculty of Medicine, Padjadjaran University, Bandung, West Java, Indonesia&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department Pathology Anatomy, Faculty of Medicine, Padjadjaran University, Bandung, West Java, Indonesia&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Radiology, Faculty of Medicine, Padjadjaran University, Bandung, West Java, Indonesia&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Tutik Sri Wahyuni</style></author><author><style face="normal" font="default" size="100%">Adita Ayu Permanasari</style></author><author><style face="normal" font="default" size="100%">Lidya Tumewu</style></author><author><style face="normal" font="default" size="100%">Aty Widyawaruyanti</style></author><author><style face="normal" font="default" size="100%">Achmad Fuad Hafid</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Qualitative and Quantitative Analysis of 70% Ethanol Extract from Ruta angustifolia for Developing Anti-Hepatitis C Agents</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Hepatitis C Virus</style></keyword><keyword><style  face="normal" font="default" size="100%">Infectious disease</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plants</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicine</style></keyword><keyword><style  face="normal" font="default" size="100%">Ruta angustifolia</style></keyword><keyword><style  face="normal" font="default" size="100%">Rutin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">682-687</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Medicinal plants are potential sources for drug candidates. It possesses with various metabolites which have many pharmacology effects. &lt;em&gt;Ruta angustifolia&lt;/em&gt; is one of medicinal plants that has been used traditionally for liver disease. Previous study it has been demonstrated to inhibit hepatitis C virus under in vitro cell culture. It decreased protein NS3 level and gave synergistic effect in combination with simeprevir and telaprevir. This plant provides a prospective candidate to develop as anti-HCV Objective: This study evaluates the phytochemistry screening for qualitative assay and determine the concentration of rutin as marker compound for developing &lt;em&gt;R. angustifolia&lt;/em&gt; extract as anti-HCV agent.&lt;strong&gt; Materials and Methods:&lt;/strong&gt; &lt;em&gt;R. angustifolia&lt;/em&gt; leaves were extracted with 70% of ethanol. Extract and rutin were analysis their anti-HCV activity by in vitro culture cells of Huh7it. The concentration of rutin was determine by TLC densitometry. &lt;strong&gt;Results:&lt;/strong&gt; The 70% ethanol extract of &lt;em&gt;R. angustifolia &lt;/em&gt;dan rutin exhibit anti-HCV activities with IC&lt;sub&gt;50&lt;/sub&gt; value of 2.9 ± 0.8 μg/ml and 28.1 ± 5.6 μg/ml, respectively. Screening phytochemistry demonstrated to contain flavonoid, terpenoid, alkaloid and polyphenols. TLC densitometry analysis yield the concentration of rutin in extract 0.06 %. &lt;strong&gt;Conclusion:&lt;/strong&gt; Extract of 70% ethanol of &lt;em&gt;R. angustifolia &lt;/em&gt;has a potential anti-HCV activity. Extract of &lt;em&gt;R. angustifolia&lt;/em&gt; may provide a good candidate for developing anti-HCV agents.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">682</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Tutik Sri Wahyuni&lt;sup&gt;1,2,&lt;/sup&gt;*, Adita Ayu Permanasari&lt;sup&gt;2&lt;/sup&gt;, Lidya Tumewu&lt;sup&gt;2&lt;/sup&gt;, Aty Widyawaruyanti&lt;sup&gt;1,2&lt;/sup&gt;, Achmad Fuad Hafid&lt;sup&gt;1,2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Science, Faculty of Pharmacy, Universitas Airlangga, Jl. Mulyorejo, Surabaya 60115, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Center of Natural Product Medicine Research and Development, Institute of Tropical Disease, Universitas Airlangga, Jl. Mulyorejo, Surabaya 60115, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Eem Masaenah</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Heri Setiawan</style></author><author><style face="normal" font="default" size="100%">Zahra Fadhilah</style></author><author><style face="normal" font="default" size="100%">Varda Arianti</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantification of Andrographolide in Andrographis paniculata (Burm.f.) Nees, Myricetin in Syzygium cumini (L.) Skeels, and Brazilin in Caesalpinia sappan L. by HPLC Method</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Andrographis paniculata</style></keyword><keyword><style  face="normal" font="default" size="100%">Caesalpinia sappan</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Marker compounds</style></keyword><keyword><style  face="normal" font="default" size="100%">Quality control</style></keyword><keyword><style  face="normal" font="default" size="100%">Syzygium cumini</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1437-1444</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction&lt;/strong&gt;: Andrographolide, myricetin, and brazilin are bioactive compounds from &lt;em&gt;Andrographis paniculata&lt;/em&gt;, &lt;em&gt;Syzygium cumini,&lt;/em&gt; and Caesalpinia &lt;em&gt;sappan &lt;/em&gt;plants that have potential as medicinal ingredients. Objectives: To determine the levels of andrographolide in A. paniculata herb extract (APE), myricetin in S. cumini leaf extract (SCE), and brazilin in &lt;em&gt;C. sappan&lt;/em&gt; wood extract (CSE) as marker compounds for extract quality control using the HPLC method. Methods: The separation was carried out on a reverse-phase C18 column (150 x 4.6 mm; 5 μm). The isocratic was prepared from methanol - water (50:50 v/v); 0.1% orthophosphoric acid - methanol (60:40 v/v); and 0,3% acetic acid - acetonitrile (85.5: 14.5 v/v) as mobile phase with flow rate 1 mL/min for andrographolide, myricetin, and brazilin determination, respectively and detection using UV detector at a wavelength of 254 nm, 369 nm, and 280 nm, respectively. Results: The linear regression for andrographolide was y = 14113x + 5948.8 (r2= 0.9994); myricetin was y = 87766x – 138895 (r2=0.9996); and brazilin was y = 18520x – 42668 (r2=0.9992). The andrographolide content in APE was found to be 14.4686 %. The myricetin content in SCE was found to be 0.3190 %. The brazilin content in CSE was found to be 2.1280 %. Conclusion: The described HPLC method was successfully used for the analysis of the APE, SCE, and CSE. This method can be used for the identification and quantification of andrographolide, myricetin, and brazilin in herbal raw materials or herbal products containing these three extracts.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1437</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Eem Masaenah&lt;sup&gt;1,2&lt;/sup&gt;, Berna Elya&lt;sup&gt;1,*&lt;/sup&gt;, Heri Setiawan&lt;sup&gt;1&lt;/sup&gt;, Zahra Fadhilah&lt;sup&gt;1&lt;/sup&gt;, Varda Arianti&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, Universitas Indonesia, Depok 16424, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Sekolah Tinggi Teknologi Industri dan Farmasi, Bogor 16151, West Java, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sergey Kondrashev</style></author><author><style face="normal" font="default" size="100%">Nadezhda Nesterova</style></author><author><style face="normal" font="default" size="100%">Alexey Luzin</style></author><author><style face="normal" font="default" size="100%">Vitaliy Kochanov</style></author><author><style face="normal" font="default" size="100%">Anna Luzina</style></author><author><style face="normal" font="default" size="100%">Alexey Matyushin</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Qualitative and Quantitative Assay of Hydroxycinnamates of Prunus spinosa L.</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Blackthorn</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbal raw material</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Hydroxycinnamic acids</style></keyword><keyword><style  face="normal" font="default" size="100%">Prunus Spinosa L.</style></keyword><keyword><style  face="normal" font="default" size="100%">Spectrophotometry</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February  2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">157-161</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Blackthorn (&lt;em&gt;Prunus spinosa &lt;/em&gt;L.) is a plant commonly found in the Russian Federation on the roadsides, forest margins, and meadows. Despite lack of recognition by the official medicine, blackthorn fruits possess antioxidant properties and are used in homeopathic preparations. They may also demonstrate antibacterial and anticancer potential due to hydroxycinnamic acids. The aim of present study was to identify and assay hydroxycinnamates in fruits of &lt;em&gt;P. spinosa&lt;/em&gt; cultivated in Moscow Region. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Fresh and dried fruits of &lt;em&gt;P. spinosa&lt;/em&gt;, gathered from plants cultivated in Moscow Region in the harvest maturity stage, were used in the study. Qualitative composition of hydroxycinnamic acids was assessed by high performance liquid chromatography, using reversed phase C18 column. Total hydroxycinnamic acids (THA) content was assessed spectrophotometrically.&lt;strong&gt; Results:&lt;/strong&gt; Similar chromatographic profiles were obtained for both fresh and dried blackthorn fruits, the two most abundant compounds being epicatechin (2.91%) and chicoric acid (2.90%). Fruits gathered in Chekhovsky District had lower content of hydroxycinnamates (0.798 ± 0.89) than those coming from Klinsky District (0.886 ± 0.92). However, the THA content in dried fruits grown in both districts was found to be similar (0.540 ± 0.71 and 0.557 ± 0.74, respectively).&lt;strong&gt; Conclusions: &lt;/strong&gt;It can be concluded that blackthorn fruits can be considered as a source of hydroxycinnamic acids, as both fresh and dried fruits contain at least eleven hydroxycinnamates. It was found that the dried fruits have similar content of hydroxycinnamic acids, independently of their origin. Future research should be aimed at drying method optimization.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">157</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sergey Kondrashev&lt;sup&gt;1&lt;/sup&gt;, Nadezhda Nesterova&lt;sup&gt;3&lt;/sup&gt;, Alexey Luzin&lt;sup&gt;1&lt;/sup&gt;, Vitaliy Kochanov&lt;sup&gt;1&lt;/sup&gt;, Anna Luzina&lt;sup&gt;4&lt;/sup&gt;, Alexey Matyushin&lt;sup&gt;2,&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Chemistry, Sechenov First Moscow State Medical University, Moscow, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Analytical and Forensic Toxicology, Sechenov First Moscow State Medical University, Moscow, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Natural Science in Pharmacy, Sechenov First Moscow State Medical University, Moscow, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Dentistry, Sechenov First Moscow State Medical University, Moscow, RUSSIAN FEDERATION.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ekaterina Vyacheslavovna Sergunova</style></author><author><style face="normal" font="default" size="100%">Alla Anatolyevna Sorokina</style></author><author><style face="normal" font="default" size="100%">Dmitry Olegovich Bokov</style></author><author><style face="normal" font="default" size="100%">Anna Igorevna Marakhova</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Qualitative and Quantitative Determination of Organic Acids in Crude Herbal Drugs and Medicinal Herbal Preparations for Quality Control in Russian Federation by Modern Physicochemical Methods</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Coulometry</style></keyword><keyword><style  face="normal" font="default" size="100%">Crude herbal drugs</style></keyword><keyword><style  face="normal" font="default" size="100%">High Performance Liquid Chromatography</style></keyword><keyword><style  face="normal" font="default" size="100%">Organic acids</style></keyword><keyword><style  face="normal" font="default" size="100%">Potentiometry</style></keyword><keyword><style  face="normal" font="default" size="100%">Redox titration</style></keyword><keyword><style  face="normal" font="default" size="100%">Titrimetric Methods</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1132-1137</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Organic acids (malic, citric, tartaric, oxalic, acetic, formic, isovaleric, ascorbic acids) make up a large group of biologically active substances and play an important role in plant and human metabolism. They are found in large quantities in the fruits of &lt;em&gt;Rosaceae&lt;/em&gt; family medicinal plants that included in State Pharmacopoeia of the Russian Federation. Standardization of crude herbal drugs containing organic acids by modern physicochemical methods is a high-priority task.&lt;strong&gt; Materials and Methods: &lt;/strong&gt;The determination of total organic acids amount was carried out in aqueous extracts from different fruits of &lt;em&gt;Rosaceae&lt;/em&gt; family plants by galvanostatic coulometry and potentiometry methods. Galvanostatic coulometry was performed with the help of the “Expert-006” coulometer with a current of 5 mA (integrated pH meter). Iodine as an electrogenerated titrant was used for ascorbic acid determination; electro generation of hydroxide ions was carried out for determination of total organic acids amount. A potentiometer “Aquilon pH-410” with attached glass and silver chloride electrodes was used for potentiometric determination of total organic acids amount. Individual organic acids have been determined by reverse-phase high-performance liquid chromatography with ultra-violet detection (RP-HPLCUV) method. The following conditions were established: Gilson HPLC system, Alltech OA- 1000 Organic Acids (6.5×300 mm, 9 μm) chromatography column, a gradient elution mode, component A of the mobile phase is 98% (0.1% phosphoric acid, 10 mM KH&lt;sub&gt;2&lt;/sub&gt;PO&lt;sub&gt;4&lt;/sub&gt;, solution in water) with 2% acetonitrile, component B is acetonitrile, the eluent feed rate is 1 ml/min.&lt;strong&gt; Results: &lt;/strong&gt;Modern physicochemical methods for the analysis of biologically active substances, organic acids, for quality control of crude herbal drugs and medicinal herbal preparations, are developed and discussed. The optimal conditions for the qualitative and quantitative organic acid analysis are selected and described taking into account modern pharmacopoeial requirements. &lt;strong&gt;Conclusion: &lt;/strong&gt;Galvanostatic coulometry and potentiometry methods, as well as RP-HPLC-UV, can be successfully used in the quality control of crude herbal drugs and medicinal herbal preparations, specifically fruits of &lt;em&gt;Rosaceae&lt;/em&gt; family plants. Development and validation of analytical methods for monitoring the content of this BAS group is an important research area in the pharmacopoeial standardization of crude herbal drugs.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1132</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ekaterina Vyacheslavovna Sergunova&lt;sup&gt;1,&lt;/sup&gt;*, Alla Anatolyevna Sorokina&lt;sup&gt;1&lt;/sup&gt;, Dmitry Olegovich Bokov&lt;sup&gt;1,2,3&lt;/sup&gt;, Anna Igorevna Marakhova&lt;sup&gt;4&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical and Natural Sciences, Sechenov First Moscow State Medical University, 8 Trubetskaya St., bldg. 2, 119991, RUSSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Analytical, Physical and Colloid Chemistry, Sechenov First Moscow State Medical University, 8 Trubetskaya St., bldg. 2, 119991, RUSSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Laboratory of Food Chemistry, Federal Research Center for Nutrition, Biotechnology and Food Safety, 2/14, Ustyinsky pr., Moscow, 109240, RUSSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Institute of Biochemical Technology and Nanotechnology, Рeoples’ Friendship University of Russia (RUDN University), Miklukho-Maklaya St., 6, Moscow, 117198, RUSSIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Thanyathorn Tangsongcharoen</style></author><author><style face="normal" font="default" size="100%">Somchai Issaravanich</style></author><author><style face="normal" font="default" size="100%">Chanida Palanuvej</style></author><author><style face="normal" font="default" size="100%">Nijsiri Ruangrungsi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantitative Analysis of Hispidulin Content in Clerodendrum petasites Roots Distributed in Thailand</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ben-Cha-Lo-Ka-Wi-Chian remedy</style></keyword><keyword><style  face="normal" font="default" size="100%">Clerodendrum petasites</style></keyword><keyword><style  face="normal" font="default" size="100%">hispidulin</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC-PDA</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1093-1099</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; &lt;em&gt;Clerodendrum petasites&lt;/em&gt; (Lour.) S. Moore (locally known as Mai-Thao-Yaai-Mom), belonging to the Verbenaceae family, is widely formulated into multi-herb remedy, Ben-Cha- Lo-Ka-Wi-Chian remedy, possessing antipyretic activity. &lt;em&gt;C. petasites&lt;/em&gt; exhibits many biological activities, such as antioxidant, anti-inflammatory, antipyretic, etc. The flavonoid hispidulin is one of the main active compounds present in &lt;em&gt;C. petasites&lt;/em&gt;, containing anti-atheromatous, antitumor and antispasmodic effects. &lt;strong&gt;Objective:&lt;/strong&gt; The present study aimed to determine the hispidulin content in the dried roots of &lt;em&gt;C. petasites &lt;/em&gt;using HPLC technique.&lt;strong&gt; Methods:&lt;/strong&gt; &lt;em&gt;C. petasites &lt;/em&gt;dried roots, collected from twelve different areas, were extracted with ethanol using Soxhlet apparatus, and then subjected to HPLC-PDA to quantify hispidulin content. The quantitative method using HPLC-PDA technique was validated.&lt;strong&gt; Results:&lt;/strong&gt; The optimized HPLC coupling with PDA detector (HPLC-PDA) was validated for the quantitative analysis of hispidulin content in &lt;em&gt;C. petasites&lt;/em&gt; roots in terms of linearity (y = 210,200,536.6667x – 448,756.2667; R&lt;sup&gt;2&lt;/sup&gt; = 0.9997), accuracy (88.82-107.69% recovery), precision (0.66% RSD for repeatability precision; 1.17% RSD for intermediate precision), limit of detection (2.30 μg/mL), limit of quantitation (7.00 μg/mL), specificity (peak purity index = 1.0000) and robustness (% RSD &amp;lt; 1). The amount of hispidulin content in the extracts of &lt;em&gt;C. petasites&lt;/em&gt; roots conducted from the validated method was found to be 0.0182 ± 0.0109 g/100 g crude drug. &lt;strong&gt;Conclusion: &lt;/strong&gt;The HPLC-PDA analysis was able to effectively determine hispidulin in &lt;em&gt;C. petasites&lt;/em&gt; roots. The hispidulin contents in &lt;em&gt;C. petasites&lt;/em&gt; dried roots from various areas in Thailand were revealed which could be used for the specification of this crude drug with reference to its chemical marker.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1093</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Thanyathorn Tangsongcharoen&lt;sup&gt;1&lt;/sup&gt;, Somchai Issaravanich&lt;sup&gt;1&lt;/sup&gt;, Chanida Palanuvej&lt;sup&gt;1,&lt;/sup&gt;* , Nijsiri Ruangrungsi&lt;sup&gt;1,2&lt;/sup&gt;&lt;/strong&gt;&lt;sup&gt; &lt;/sup&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Public Health Sciences Program, College of Public Health Sciences, Chulalongkorn University, Bangkok 10330, THAILAND.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy, College of Pharmacy, Rangsit University, Pathum Thani 12000, THAILAND.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">La Hamidu</style></author><author><style face="normal" font="default" size="100%">Aktsar Roskiana Ahmad</style></author><author><style face="normal" font="default" size="100%">Ahmad Najib</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Qualitative and Quantitative Test of Total Flavonoid Buni Fruit (Antidesma bunius (L.) Spreng) with UV-Vis Spectrophotometry Method</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antidesma bunius L. Spreng</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoid content</style></keyword><keyword><style  face="normal" font="default" size="100%">Spectrophotometry UV-VIS</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/367</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">60-63</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The aim of this research is to determine of total flavonoid content in the Buni fruit (&lt;em&gt;Antidesma bunius &lt;/em&gt;L. Spreng) extract. The extract was produced by stratified maceration method with the different solvent, i.e &lt;em&gt;n&lt;/em&gt;-Hexane, Ethyl acetate and ethanol. The analysis of chemical compound using chemical reagent and Thin Layer Chromatography (TLC) method. The method is used to determines total flavonoid contains Buni fruit (&lt;em&gt;Antidesma bunius&lt;/em&gt; L.) extract was based on the amount of Rutin Equivalent (RE) were used. The result shows that the flavonoid content higher in the &lt;em&gt;n&lt;/em&gt;-Hexane extract is 10.72 %, then ethyl acetate extract is 7.9 % and 3.56 % ethanol extract was counted to or as a Rutin.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">60</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;La Hamidu&lt;sup&gt;1&lt;/sup&gt;*, Aktsar Roskiana Ahmad&lt;sup&gt;2&lt;/sup&gt;, Ahmad Najib&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Pharmacognosy-Phytochemistry Laboratory, Faculty of Pharmacy, Universities Muslim Indonesia, Makassar, INDONESIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ridzwan Norhaslinda</style></author><author><style face="normal" font="default" size="100%">Jumli Mimie Noratiqah</style></author><author><style face="normal" font="default" size="100%">Baig Atif Amin</style></author><author><style face="normal" font="default" size="100%">Rohin Mohd Adzim Khalili</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantitative and Optimization of Anthocyanin Extracted from Pomegranate (Punica Granatum) Extract by High-Performance Liquid Chromatography (HPLC)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">5-diglucoside</style></keyword><keyword><style  face="normal" font="default" size="100%">Cyanidin 3</style></keyword><keyword><style  face="normal" font="default" size="100%">Cyanidin 3-glucoside</style></keyword><keyword><style  face="normal" font="default" size="100%">Pelargonidin 3</style></keyword><keyword><style  face="normal" font="default" size="100%">Pelargonidin 3-glucoside</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/645</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">650-653</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; &lt;em&gt;P. granatum&lt;/em&gt; is one of the oldest edible fruits of tropical and subtropical regions. This fruit had high antioxidant contained by hydrolysable tannins and anthocyanin compounds that give many health benefit properties. This study aims to quantify and optimized anthocyanin from &lt;em&gt;P. granatum&lt;/em&gt; extract. &lt;strong&gt;Methods:&lt;/strong&gt; A total of 50g of the flesh was soaked into two different polar solvents; water and 50% ethanol within a ratio of 1:10; w/v for 24-hr. Then, three different methods of extraction were done and test each with HPLC analytical, respectively. &lt;strong&gt;Results:&lt;/strong&gt; The validated method proved to be linear in the range of 5 &amp;ndash; 30 ug/mL and with LOD and LOQ determined respectively for Cy3, Cy3, 5, Pg3, and Pg3, 5. The method also shows recovery (%) close to 100 when accuracy was accessed. For samples, blender water extract had a higher composition of Cy3, Cy3, 5 and Pg3, 5 (22.77 &amp;plusmn; 8.82 mg/100 g e.p; 25.36 &amp;plusmn; 9.95 mg/100 g e.p; 11.16 &amp;plusmn; 5.85 mg/100 g e.p) content as compared to other. &lt;strong&gt;Conclusion:&lt;/strong&gt; As a conclusion, the present methodology proved to be capable of detecting and quantifying Cy3, Cy3, 5, Pg3, Pg3, 5 in a single run. Also, comparatively the composition of each AC detected in blender water extract is significantly higher in value than the other methods. It should regard as a valuable source of antioxidant with the potential used for health benefits properties worldwide.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">650</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ridzwan Norhaslinda&lt;sup&gt;1&lt;/sup&gt;, Jumli Mimie Noratiqah&lt;sup&gt;1&lt;/sup&gt;, Baig Atif Amin&lt;sup&gt;2&lt;/sup&gt;, Rohin Mohd Adzim Khalili&lt;sup&gt;1,3,4&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;School of Nutrition and Dietetic, Faculty of Health Sciences, University Sultan Zainal Abidin (UniSZA), Gong Badak Campus, Kuala Nerus, Terengganu, MALAYSIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Medicine, University Sultan Zainal Abidin, Medical Campus, Jalan Sultan Mahmud, Kuala Terengganu, Terengganu Darul Iman, MALAYSIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Centre for Continuing Education (CCE), Universiti Sultan Zainal Abidin (UniSZA), Gong Badak Campus, 21300 Kuala Nerus, Terengganu, MALAYSIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Institute for Community (Health) Development, Universiti Sultan Zainal Abidin (UniSZA), Gong Badak Campus, 21300 Kuala Nerus, Terengganu, MALAYSIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Jumli Mimie Noratiqah</style></author><author><style face="normal" font="default" size="100%">Ridzwan Norhaslinda</style></author><author><style face="normal" font="default" size="100%">Baig Atif Amin</style></author><author><style face="normal" font="default" size="100%">Rohin Mohd Adzim Khalili</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantitative and Optimization of Phenolic Acid Extracted from Pomegranate by High Performance Liquid Chromatography (HPLC)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Caffeic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">Ellagic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">Ferulic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">Gallic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Pomegranate extract</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">969-972</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; Pomegranate is scientifically known as &lt;em&gt;Punica granatum&lt;/em&gt; L. which is a nutrient dense fruit rich in phytochemical compounds. Phenolic content is the main compound attribute for the most of the functional properties in pomegranate. The aim of this study is to quantify and optimize the composition of phenolic acids extracted from pomegranate extract by using High-performance Liquid Chromatography (HPLC). &lt;strong&gt;Method:&lt;/strong&gt; The pomegranate extracted with three different methods by using two different solvents which is 50% ethanol and water. The methods were blended (aril+ seed), Soaking (aril+ seed) and soaking + squeezed manually. HPLC-PDA was used as equipment to quantify and optimize the phenolic acids extracted from pomegranate. Result: Validation method of HPLC was analysed according to the percentage of recovery, LOD, LOQ and coefficient correlation. Result showed that GA was detected in all sample from different method of extraction applied while CA compound not detected in any of extraction method applied. FA compound was only detected in blended method by 50% ethanol and water as solvent while EA compound was detected only in water extraction of all three methods applied. &lt;strong&gt;Conclusion:&lt;/strong&gt; As a conclusion, according to the standard calibration data curve showed that this method proved to detect and quantify the targeted compounds. By comparing the data obtained from this study, it showed that water blended extract method is significantly higher content of targeted compound except for the CA compound. To the best of our knowledge, this sample can be a valuable source of antioxidant for better used in health benefits.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">969</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Jumli Mimie Noratiqah&lt;sup&gt;1&lt;/sup&gt;, Ridzwan Norhaslinda&lt;sup&gt;1&lt;/sup&gt;, Baig Atif Amin&lt;sup&gt;2&lt;/sup&gt;, Rohin Mohd Adzim Khalili&lt;sup&gt;1,3,4* &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;School of Nutrition and Dietetic, Faculty of Health Sciences, Universiti Sultan Zainal Abidin (UniSZA), Gong Badak Campus, 21300 Kuala Nerus, Terengganu, MALAYSIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Medicine, Universiti Sultan Zainal Abidin (UniSZA), Medical Campus, Jalan Sultan Mahmud, 20400 Kuala Terengganu, Terengganu, MALAYSIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Centre for Continuing Education (CCE), Universiti Sultan Zainal Abidin (UniSZA), Gong Badak Campus, 21300 Kuala Nerus, Terengganu, MALAYSIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Institute for Community (Health) Development, Universiti Sultan Zainal Abidin (UniSZA), Gong Badak Campus, 21300 Kuala Nerus, Terengganu, MALAYSIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ming Shin Neo</style></author><author><style face="normal" font="default" size="100%">Shraddha Manish Gupta</style></author><author><style face="normal" font="default" size="100%">Tahir Mehmood Khan</style></author><author><style face="normal" font="default" size="100%">Manish Gupta</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantification of Ethanol Content in Traditional Herbal Cough Syrups</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alcohol content</style></keyword><keyword><style  face="normal" font="default" size="100%">Enzymatic analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Ethanol concentration</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbal cough medicine</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbal preparation</style></keyword><keyword><style  face="normal" font="default" size="100%">Quantitative analysis.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/181</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">821-827</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; The use of alcohol as an excipient in pharmaceutical preparations raises safety concerns, especially when used in high concentration. This study aims to scrutinize the ethanol concentration in traditional herbal cough syrups available over-the-counter (OTC) in Malaysia. &lt;strong&gt;Method:&lt;/strong&gt; Enzymatic analysis was adopted to estimate the alcohol contents of five selected syrups. The principle reaction involved ethanol oxidation by nicotinamide-adenine dinucleotide (NAD) in the presence of the enzyme alcohol dehydrogenase (ADH), forming acetaldehyde, reduced NAD (NADH) and a proton. The ethanol concentration of each syrup was quantitatively determined by detecting NADH using UV spectrophotometry at detection wavelength of 340 nm. &lt;strong&gt;Results:&lt;/strong&gt; The ethanol percentage by volume (% v/v) in the tested syrups ranges from 0.102% to 2.576%. All five syrups studied comply with the FDA requirement for drugs for adults and children &amp;gt;6 years since they do not contain more than 5% ethanol. However, three syrups do not fulfil the requirement for use in children &amp;lt;6 years as they contain higher than 0.5% ethanol, yet they are inappropriately indicated on their packaging for use in children &amp;gt;3 years. In terms of safety, all studied syrups fulfil European Medicine Agency&amp;rsquo;s (EMA) recommendation as they will not induce a blood alcohol concentration (BAC) higher than 0.125g/L after a single dose. Nevertheless, none of these syrups comply with Malaysian Drug Registration Guidance on labelling requirements as they do not disclose their alcohol contents on the packaging. &lt;strong&gt;Conclusion:&lt;/strong&gt; More rigorous regulation on alcohol content in herbal preparations, and disclosure of alcohol content in product packagings should be enforced.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">821</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ming Shin Neo&lt;sup&gt;1&lt;/sup&gt;, Shraddha Manish Gupta&lt;sup&gt;1&lt;/sup&gt;,&lt;sup&gt;2&lt;/sup&gt;, Tahir Mehmood Khan&lt;sup&gt;1&lt;/sup&gt;, Manish Gupta&lt;sup&gt;1*&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;School of Pharmacy, Monash University Malaysia, Selangor, MALAYSIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Gurukrupa Institute of Pharmacy, NH 222, Near Chhatrapati Sugar Factory, Malipargaon Phata , Majalgoan, Beed 431131, Maharashtra, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sajad Hassan Wani</style></author><author><style face="normal" font="default" size="100%">Hilal Ahmad Bhat</style></author><author><style face="normal" font="default" size="100%">Javid Iqbal Mir</style></author><author><style face="normal" font="default" size="100%">Shahid Ali Akbar</style></author><author><style face="normal" font="default" size="100%">Sajad Un Nabi</style></author><author><style face="normal" font="default" size="100%">Desh Beer Singh</style></author><author><style face="normal" font="default" size="100%">Nazeer Ahmad</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantitative Analysis of Irigenin in the Different Species of Iris Plant by RP- HPLC and its Efficacy Against Different Plant Pathogens</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bio efficacy</style></keyword><keyword><style  face="normal" font="default" size="100%">Irigenin</style></keyword><keyword><style  face="normal" font="default" size="100%">Iris Plant</style></keyword><keyword><style  face="normal" font="default" size="100%">RP-HPLC</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/377</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">s23-s27</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;Irigenin belongs to family of &lt;em&gt;isoflavonoids&lt;/em&gt;, isolated from &lt;em&gt;Iris Plant&lt;/em&gt; of Kashmir Himalaya. A rapid and specific reverse phase high pressure chromatography (RP HPLC) method for quantitative analysis of irigenin in the different species of &lt;em&gt;Iris Plant&lt;/em&gt; was developed. The samples were analyzed on RP-C&lt;sub&gt;18&lt;/sub&gt; e column (chromolith, 5&amp;mu;m, 4.6&amp;times;100 mm). The HPLC system was operated at ambient temperature (&amp;plusmn;30c). The mobile phase consisted of methanol: water. The detecting wavelength at 260 nm and flow rate of 0.6 ml/min. The standard irigenin was diluted using the mobile phase at a known concentration of 1mg/ml; the sample was filtered through sample filter of 0.45 &amp;mu; pore size. The filtrate was introduced on to a reverse phase analytical column. The content of irigenin in the different species of &lt;em&gt;Iris Plant&lt;/em&gt; was determined. The HPLC showed an excellent performance in separating the irigenin in different species of &lt;em&gt;Iris Plant&lt;/em&gt;. Furthermore, the antipathogenic activity. The test compound at each respective concentration was found to be statistically superior against scab. Furthermore, the test compound @ 5000 ppm proved significantly most effective by providing (82.49%) inhibition in the mycelia growth of apple scab. It was followed by fusarium (77.27%) at 5000 ppm. Lowest reduction in mycelia growth (65.78%) was recorded in &lt;em&gt;marssonina&lt;/em&gt; and did not differ significantly from Alternaria (67.47%) at 5000 ppm. Furthermore, lowest inhibition of mycelia growth was recorded at 1000 ppm. Similar trend was recorded for rest of the pathogens i.e. highest reduction at 5000 ppm, lowest at 1000 ppm and at 2000, 3000 and 4000 ppm it ranges between the first two but increases with increase in concentration. From this study irigenin is potent compound which can be used for controlling the growth of respective pathogens.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">s23</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Sajad Hassan Wani&lt;sup&gt;1&lt;/sup&gt;*, Hilal Ahmad Bhat&lt;sup&gt;1&lt;/sup&gt;, Javid Iqbal Mir&lt;sup&gt;1&lt;/sup&gt;, Shahid Ali Akbar&lt;sup&gt;2&lt;/sup&gt;, Sajad un Nabi&lt;sup&gt;3&lt;/sup&gt;, Desh Beer Singh&lt;sup&gt;4&lt;/sup&gt;, Nazeer Ahmad&lt;sup&gt;5 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Biotechnology division, Central Institute of Temperate Horticulture- ICAR, Srinagar, Jammu and Kashmir, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Entomology division, Central Institute of Temperate Horticulture- ICAR, Srinagar, Jammu and Kashmir, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Plant Pathology, Central Institute of Temperate Horticulture- ICAR, Srinagar, Jammu and Kashmir, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Central Institute of Temperate Horticulture- ICAR, Srinagar, Jammu and Kashmir, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Sheri Kashmir University of Agriculture Science and Technology Kashmir (SKUAST-K), Jammu, Jammu and Kashmir, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Venkata Siva Satyanarayana Kantamreddi</style></author><author><style face="normal" font="default" size="100%">V. Thirumala Veni</style></author><author><style face="normal" font="default" size="100%">G. Y. S. K. Swamy</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Quantitative Approach to Estimate both Essential and Non-essential Elements in Some Commercial Samples of Triphala churna by using WD-XRF Spectrometry</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ayurveda</style></keyword><keyword><style  face="normal" font="default" size="100%">Elemental analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">ICP-MS</style></keyword><keyword><style  face="normal" font="default" size="100%">ISM</style></keyword><keyword><style  face="normal" font="default" size="100%">Triphala churna</style></keyword><keyword><style  face="normal" font="default" size="100%">WD-XRF</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2017 </style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">/files/PJ-9-3/10.5530pj.2017.3.64</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">378-381</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; The need for quality control of herbal drugs is in demand in order to ensure the purity, safety and efficacy of herbal products. A total of 19 elements including essential and non-essential elements were characterized in five commercial samples of &lt;em&gt;Triphala churna&lt;/em&gt; using WD-XRF spectrometry. &lt;strong&gt;Method:&lt;/strong&gt; The WD-XRF method was validated for each element by a pre-calibrated program using five Chinese certified reference materials of vegetable standards (NCS ZC73012, NCS ZC73013, NCS ZC73017, NCS ZC85006 and NCS DC73348). &lt;strong&gt;Results:&lt;/strong&gt; The following elements were detected in all the samples out of 19 elements tested with increasing order of concentrations (mg/kg): Cr (3) &amp;lt; Cu (7) &amp;lt; Ba (24) &amp;lt; Zn (31) &amp;lt; Pb (46) &amp;lt; Mn (57) &amp;lt; S (700) &amp;lt; Na (1064) &amp;lt; Mg (1250) &amp;lt; Fe (1329) &amp;lt; P (1400) &amp;lt; Cl (2960) &amp;lt; Ca (3110) &amp;lt; Si (4350) &amp;lt; K (15130). Lead (41-46 mg/kg), a nonessential element was found above its PDE limit (&amp;le; 10 mg/kg). &lt;strong&gt;Conclusion:&lt;/strong&gt; WD-XRF method was found simple, rapid, reliable and non-destructive technique to investigate the elemental concentrations in herbal drugs.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">378</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Venkata Siva Satyanarayana Kantamreddi&lt;sup&gt;1*&lt;/sup&gt;, V. Thirumala Veni&lt;sup&gt;1&lt;/sup&gt; and G. Y. S. K. Swamy&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Centre for Chemical Analysis, Central Research Laboratory, GIT, GITAM University, Visakhapatnam, Andhra Pradesh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratory of X-ray Crystallography, Indian Institute of Chemical Technology, CSIR, Hyderabad, Telangana, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Siva Hemalatha</style></author><author><style face="normal" font="default" size="100%">Priyanka Sharma</style></author><author><style face="normal" font="default" size="100%">Satyendra Kuldip Prasad</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quality Control standardization of Wild Himalayan Pear: Pyrus pashia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">HPLC.</style></keyword><keyword><style  face="normal" font="default" size="100%">Lupeol</style></keyword><keyword><style  face="normal" font="default" size="100%">Pyrus pashia</style></keyword><keyword><style  face="normal" font="default" size="100%">standardization</style></keyword><keyword><style  face="normal" font="default" size="100%">total flavonoid content</style></keyword><keyword><style  face="normal" font="default" size="100%">total phenolic content</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June/2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">352-360</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align:justify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;To establish the pharmacognostical and phytochemical standardization parameters of &lt;em&gt;Pyrus pashia&lt;/em&gt; fruits in order to ensure quality and safety of this traditionally acclaimed medicinal tree. &lt;strong&gt;Methods:&lt;/strong&gt; The fresh fruits of &lt;em&gt;P. pashia &lt;/em&gt;were collected and dried. Fruit was subjected to various pharmacognostical investigations, Extraction procedures, and preliminary phytochemical screening, according to WHO guidelines. Ethanolic extract was standardized to total phenolic and flavonoid content, followed by phytochemical quantification of &lt;em&gt;P. pashia&lt;/em&gt; extract using lupeol as a chemical marker by HPLC method. &lt;strong&gt;Results: &lt;/strong&gt;In the present study, microscopy of the fruit showed typical characteristics of berry, having thick fleshy pericarp differentiated into thin epicarp and thick mesocarp having wide radiating carpel chambers with one or two seeds attached in axile placentum. Further, physicochemical evaluation was done like, loss on drying, total ash value, acid insoluble ash value, water soluble ash value, fluorescence analysis etc. Heavy metal and pesticide residue analysis was also performed. Furthermore, ethanolic extract of &lt;em&gt;Pyrus pashia&lt;/em&gt; (EPP) obtained from cold maceration and phytochemical screening of different fractions obtained by liquid partitioning revealed the presence of various secondary metabolites such as glycosides, steroids, triterpenoids, phenols flavonoids etc. Moreover, the total phenolic content and total analysis revealed that fruits are rich source of phenols and flavonoid. The HPLC chromatogram suggested that EPP contained 4.24% w/w of lupeol. &lt;strong&gt;Conclusion:&lt;/strong&gt; Pharmacognostical and phytochemical investigation will ensure quality and safety of this medicinal plant, furthermore HPLC quantification will aid in authentication and development of monograph.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">352</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Siva Hemalatha&lt;sup&gt;1&lt;/sup&gt;*, Priyanka Sharma&lt;sup&gt;1&lt;/sup&gt;, Satyendra Kuldip Prasad&lt;sup&gt;2&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutics, Indian Institute of Technology, Banaras Hindu University, Varanasi-221005, INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmaceutical Sciences, Rashtrakant Tukadoji Maharaj Nagpur University, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Deepali Pandey</style></author><author><style face="normal" font="default" size="100%">Apurva Joshi</style></author><author><style face="normal" font="default" size="100%">S. Hemalatha</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quality Control Standardization and In-Vitro Antioxidant Activity of Aganosma dichotoma K. Schum Root</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">01/2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">74-82</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;&lt;em&gt;Aganosma dichotoma&lt;/em&gt; K. Schum (AD) is a large climber with very stout stem belonging to the family &lt;em&gt;Apocynaceae&lt;/em&gt;. The Plant has significant medicinal value as described in traditional system of medicine. The objective of the present study is to scientifically develop a standard monograph for AD on the basis of its pharmacognostical and phytochemical aspects.&lt;strong&gt; Methods:&lt;/strong&gt; The study includes quality control standardization as per the standard methods provided in World Health Organization for standardization of medicinal plants. Fluorescence drug analysis, preliminary phytochemical screening of different fractions, quantification of some phytoconstituents and &lt;em&gt;in-vitro&lt;/em&gt; antioxidant activity were also carried out. Quantification of Quercetin in the ethanolic extract of&lt;em&gt; A. dichotoma&lt;/em&gt; was determined by HPTLC analysis. The ethanolic extract of root of &lt;em&gt;A. dichotoma&lt;/em&gt; was subjected to &lt;em&gt;in-vitro&lt;/em&gt; antioxidant activity. &lt;strong&gt;Results:&lt;/strong&gt; The diagnostic characters of &lt;em&gt;A. dichotoma&lt;/em&gt; root were evaluated on the basis of macroscopical and microscopical characters. Physicochemical parameters were evaluated such as 6.7% w/w loss on drying with; ash values (in % w/w): 13.75 total ash, 5.75 acid-insoluble ash, 3.6 water-soluble ash; Extractive values (% w/w): 12.75 water, 11.82 ethanol, 2.26 ethyl acetate, 3.13 chloroform, and 3.16 pet ether; foaming index 181.81; swelling index 3.2 ml/g; hemolytic activity 227.89 unit/gm of powder drug and crude fiber content was 19.4%. Total numbers of starch grain in 1 mg of root powder were 2,49,981. Quantification of quercetin in the ethanolic extract was assessed by HPTLC analysis and was found to contain 2.40%, w/w. &lt;strong&gt;Conclusion:&lt;/strong&gt; The parameters determined in the present study may provide necessary information for identification and authentication of plant material.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">74</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Deepali Pandey, Apurva Joshi, S. Hemalatha&lt;sup&gt;* &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;Department of Pharmaceutics, Indian Institute of Technology (Banaras Hindu University), Varanasi (U.P.)221005, India.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Deepali Pandey</style></author><author><style face="normal" font="default" size="100%">Apurva Joshi,</style></author><author><style face="normal" font="default" size="100%">Hemalatha, S.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quality Control Standardization and In-Vitro Antioxidant Activity of Aganosma dichotoma K. Schum Root</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Aganosma dichotoma</style></keyword><keyword><style  face="normal" font="default" size="100%">HPTLC</style></keyword><keyword><style  face="normal" font="default" size="100%">in-vitro antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacognosy</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">27th Nov, 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">74-82</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align:justify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;&lt;em&gt;Aganosma dichotoma&lt;/em&gt; K. Schum (AD) is a large climber with very stout stem belonging to the family Apocynaceae. The Plant has significant medicinal value as described in traditional system of medicine. The objective of the present study is to scientifically develop a standard monograph for AD on the basis of its pharmacognostical and phytochemical aspects. &lt;strong&gt;Methods:&lt;/strong&gt; The study includes quality control standardization as per the standard methods provided in World Health Organization for standardization of medicinal plants. Fluorescence drug analysis, preliminary phytochemical screening of different fractions, quantification of some phytoconstituents and&lt;em&gt; in-vitro &lt;/em&gt;antioxidant activity were also carried out. Quantification of Quercetin in the ethanolic extract of&lt;em&gt; A. dichotoma &lt;/em&gt;was determined by HPTLC analysis. The ethanolic extract of root of&lt;em&gt; A.&lt;/em&gt;&lt;em&gt;dichotoma &lt;/em&gt;was subjected to&lt;em&gt; in-vitro &lt;/em&gt;antioxidant activity. &lt;strong&gt;Results:&lt;/strong&gt; The diagnostic characters of &lt;em&gt;A.dichotoma &lt;/em&gt;root were evaluated on the basis of macroscopical and microscopical characters. Physicochemical parameters were evaluated such as 6.7% w/w loss on drying with; ash values (in % w/w): 13.75 total ash, 5.75 acid-insoluble ash, 3.6 water-soluble ash; Extractive values (% w/w): 12.75 water, 11.82 ethanol, 2.26 ethyl acetate, 3.13 chloroform, and 3.16 pet ether; foaming index 181.81; swelling index 3.2 ml/g; hemolytic activity 227.89 unit/gm of powder drug and crude fiber content was 19.4%. Total numbers of starch grain in 1 mg of root powder were 2,49,981. Quantification of quercetin in the ethanolic extract was assessed by HPTLC analysis and was found to contain 2.40%, w/w. &lt;strong&gt;Conclusion: &lt;/strong&gt;The parameters determined in the present study may provide necessary information for identification and authentication of plant material.&lt;/p&gt;&lt;p style=&quot;text-align:justify&quot;&gt;&lt;strong&gt;Key words:&lt;/strong&gt;&lt;em&gt;Aganosma dichotoma&lt;/em&gt;, HPTLC,&lt;em&gt; in-vitro&lt;/em&gt; antioxidant activity, Pharmacognosy.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><custom1><style face="normal" font="default" size="100%">Deepali Pandey, Apurva Joshi, S. Hemalatha</style></custom1><section><style face="normal" font="default" size="100%">74</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Deepali Pandey, Apurva Joshi, S. Hemalatha&lt;sup&gt;*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;Applied Nutrition Division, Defence Food Research Laboratory (DRDO), Ministry of Defence, India&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Weifang Long</style></author><author><style face="normal" font="default" size="100%">Qi Ding</style></author><author><style face="normal" font="default" size="100%">Yujie Chen</style></author><author><style face="normal" font="default" size="100%">Jiqing Hu</style></author><author><style face="normal" font="default" size="100%">Luyang Li</style></author><author><style face="normal" font="default" size="100%">Fei Zhang</style></author><author><style face="normal" font="default" size="100%">Dingrong Wan</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantitative Determination and Variation Tendencies of Flavonoids in Five Selaginella Plant Drugs</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Amentoflavone content</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Selaginella</style></keyword><keyword><style  face="normal" font="default" size="100%">Total flavonoids content</style></keyword><keyword><style  face="normal" font="default" size="100%">UV-Vis spectrophotometry</style></keyword><keyword><style  face="normal" font="default" size="100%">Variation tendencies</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Nov-Dec 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">378-382</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">378</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Weifang Long&lt;sup&gt;1&lt;/sup&gt;, Qi Ding&lt;sup&gt;1&lt;/sup&gt;, Yujie Chen&lt;sup&gt;2&lt;/sup&gt;, Jiqing Hu&lt;sup&gt;1&lt;/sup&gt;, Luyang Li&lt;sup&gt;1&lt;/sup&gt;, Fei Zhang&lt;sup&gt;1&lt;/sup&gt; and Dingrong Wan&lt;sup&gt;1,3*&lt;/sup&gt;&lt;/strong&gt; &lt;sup&gt;1&lt;/sup&gt;Department of Pharmacy, College of Pharmacy, South-Central University for Nationalities, Wuhan, China. &lt;sup&gt;2&lt;/sup&gt;Department of Pharmacy, Hainan Provincial Key Laboratory of R &amp;amp; D of Tropical Herbs, School of Pharmacy, Hainan Medical University, Haikou, China. 3The Modernization Engineering Technology Research Center of Ethnic Minority Medicine of Hubei Province, China.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Kayalvizhi M,</style></author><author><style face="normal" font="default" size="100%">Richa Shri</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Qualitative and Quantitative Analysis of Nyctanthes arbortristis Linn leaf extracts by HPTLC</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">HPTLC qualitative and quantitative evaluation</style></keyword><keyword><style  face="normal" font="default" size="100%">Nyctanthes arbortristis</style></keyword><keyword><style  face="normal" font="default" size="100%">ommercial formulations</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">8th April 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">117-130</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;em&gt;Nyctanthes arbortristis&lt;/em&gt; L. (Oleaceae) or &amp;ldquo;night jasmine&amp;rdquo; is cultivated for its fragrant flowers and is widely used in traditional systems of medicine as an anthelmintic, cholagogue, laxative and antimalarial. The plant has been studied pharmacognostically and certain standards are available. However there are no reports on HPTLC quality assessment of &lt;em&gt;Nyctanthes arbortristis&lt;/em&gt;. Hence the present study involves the development of qualitative HPTLC fingerprint profile of n-hexane, ethyl acetate, methanol extracts of leaves of &lt;em&gt;N. arbortristis&lt;/em&gt; followed by quantitation of marker compounds &amp;acirc;-sitosterol, &amp;acirc;-amyrin in n-hexane extract and caffeic acid in ethyl acetate extract. The developed methods were used for comparison of plant extracts with a few commercial formulations containing &lt;em&gt;N. arbortristis&lt;/em&gt;. These HPTLC methods can be used easily for evaluation of quality of plants collected from different sources as well as for commercial formulations containing &lt;em&gt;N. arbortristis&lt;/em&gt;.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words: &lt;/strong&gt;&lt;em&gt;Nyctanthes arbortristis&lt;/em&gt;, commercial formulations, HPTLC qualitative and quantitative evaluation.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Kayalvizhi M and Richa Shri&lt;sup&gt;*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala-147002, Punjab.&lt;/p&gt;</style></auth-address></record></records></xml>