<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Candra Irawan</style></author><author><style face="normal" font="default" size="100%">Maman Sukiman</style></author><author><style face="normal" font="default" size="100%">Ismail</style></author><author><style face="normal" font="default" size="100%">Imalia Dwi Putri</style></author><author><style face="normal" font="default" size="100%">Andita Utami</style></author><author><style face="normal" font="default" size="100%">Andrean Nur Pratama</style></author><author><style face="normal" font="default" size="100%">M. Ilham Kumala Zalni</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant Capacity and Potential as an Alpha-Glucosidase Inhibitor in Phaleria macrocarpa (Scheff.) Boerl Fruit Peel Ultrasonic Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alpha-glucosidase</style></keyword><keyword><style  face="normal" font="default" size="100%">Antidiabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Phaleria macrocarpa (Scheff.) Boerl</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">305-312</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;em&gt;Phaleria macrocarpa &lt;/em&gt;(Scheff.) Boerl is native to the tropical region of Papua Island, Indonesia, and has traditionally been used as a herbal drink, either alone or in combination with other medicinal plants, to treat diseases such as cancer, hypertension, and diabetes mellitus. This study aimed to obtain the fruit peel extract of &lt;em&gt;Phaleria macrocarpa&lt;/em&gt; (Scheff.) Boerl. through the application of ultrasound-assisted extraction (UAE) with variations in time and amplitude to produce optimal extraction conditions. The potential of the extract as an antioxidant using the cupric ion reducing antioxidant capacity (CUPRAC) and ferric reducing antioxidant power (FRAP) methods, and its potential as an antidiabetic through alpha glucosidase inhibition. The optimum extract selected was extract C (extraction time was 45 minutes and amplitude 60%) with IC&lt;sub&gt;50&lt;/sub&gt; values for antioxidant activity in the CUPRAC method of 39.63 ± 0.009 mg/L and the FRAP method of 77.37 ± 0.8 mg/L, while the inhibition of alpha glucosidase was 0.45 ± 0.007 mg/L. It can be concluded that the ethanol extract of &lt;em&gt;Phaleria macrocarpa &lt;/em&gt;fruit peel has the potential as a source of antioxidants and anti-diabetic.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><accession-num><style face="normal" font="default" size="100%">08</style></accession-num><section><style face="normal" font="default" size="100%">305</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Candra Irawan&lt;sup&gt;1&lt;/sup&gt;, Maman Sukiman&lt;sup&gt;2,*&lt;/sup&gt;, Ismail&lt;sup&gt;3&lt;/sup&gt;, Imalia Dwi Putri&lt;sup&gt;1&lt;/sup&gt;, Andita Utami&lt;sup&gt;3&lt;/sup&gt;, Andrean Nur Pratama&lt;sup&gt;4&lt;/sup&gt;, M. Ilham Kumala Zalni&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Food Nanotechnology, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Industrial Waste Treatment, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Chemical Analysis, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;4&lt;/sup&gt;Research and Development Planning Agency, Tanggamus District, Lampung, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sri Ningsih</style></author><author><style face="normal" font="default" size="100%">Fifit Juniarti</style></author><author><style face="normal" font="default" size="100%">Idah Rosidah</style></author><author><style face="normal" font="default" size="100%">Adam Arditya Fajriawan</style></author><author><style face="normal" font="default" size="100%">Kurnia Agustini</style></author><author><style face="normal" font="default" size="100%">Syofi Rosmalawati</style></author><author><style face="normal" font="default" size="100%">Agung Eru Wibowo</style></author><author><style face="normal" font="default" size="100%">Erliana Sasikirana</style></author><author><style face="normal" font="default" size="100%">Wahono Sumaryono</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Study of the Effect of Lampeni (Ardisia humilis Vahl.) Planting Condition toward the Alpha-glucosidase Inhibition Activity in vitro</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alpha-glucosidase</style></keyword><keyword><style  face="normal" font="default" size="100%">Ardisia humilis Vahl.</style></keyword><keyword><style  face="normal" font="default" size="100%">Lampeni</style></keyword><keyword><style  face="normal" font="default" size="100%">Open-air</style></keyword><keyword><style  face="normal" font="default" size="100%">Shedding house</style></keyword><keyword><style  face="normal" font="default" size="100%">total phenolic</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">377-385</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;The quality of a medicinal plant is influenced by agronomic conditions and harvesting time. &lt;strong&gt;Objective: &lt;/strong&gt;This study aimed to evaluate the effect of planting method (openair (OA) and shedding house (SH)) and harvesting time (2, 4, 6 months) of Lampeni (Ardisia humilis Vahl.) toward the inhibitory activity of alpha-glucosidase. &lt;strong&gt;Methods: &lt;/strong&gt;The Lampeni seedling were placed under controlled light conditions (SH) and on direct sun exposure (OA). Harvesting of the leaves was carried out at the age of 2, 4, and 6 months after plantation (2m, 4m, and 6m). Each leaves dry powder was refluxed with methanol 70% and followed by liquid-liquid partition using n-hexane, ethyl acetate (EtOAc), and water. All samples were evaluated toward inhibition of the alpha-glucosidase enzyme &lt;em&gt;in vitro&lt;/em&gt;. Total phenol levels were determined using Folin-Ciocalteu reagent. &lt;strong&gt;Results: &lt;/strong&gt;The results showed that EtOAc fractions of both plantation techniques exhibited the highest inhibition of alpha-glucosidase. The highest activity was demonstrated by the 4m-OA-EtOAc fraction (IC&lt;sub&gt;50&lt;/sub&gt;, 93.50 ppm) and followed by the 6m-OA-EtOAc fraction (IC&lt;sub&gt;50&lt;/sub&gt;, 98.13 ppm). Based on the kinetic study, the inhibition type of the two most active samples were categorized as a non-competitive type. Total phenolic contents were decreased in the following order: 6m-SH-EtOAc &amp;gt; 4m-OA-EtOAc &amp;gt; 6m-OAEtOAc &amp;gt; 4m-SH-EtOAc fraction. It was shown that there was no positive correlation between the strength of inhibition with total phenolic content. &lt;strong&gt;Conclusions:&lt;/strong&gt; This study concluded that Lampeni at open-air plantation harvested on fourth months demonstrated the highest alpha-glucosidase inhibitory activity, although there was no positive correlation between the inhibition activity and phenolic content.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">377</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sri Ningsih&lt;sup&gt;1,&lt;/sup&gt;*, Fifit Juniarti&lt;sup&gt;1&lt;/sup&gt;, Idah Rosidah&lt;sup&gt;1&lt;/sup&gt;, Adam Arditya Fajriawan&lt;sup&gt;1&lt;/sup&gt;, Kurnia Agustini&lt;sup&gt;1&lt;/sup&gt;, Syofi Rosmalawati&lt;sup&gt;2&lt;/sup&gt;, Agung Eru Wibowo&lt;sup&gt;2&lt;/sup&gt;, Erliana Sasikirana&lt;sup&gt;3&lt;/sup&gt;, Wahono Sumaryono&lt;sup&gt;3&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Center for Pharmaceutical and Medical Technology, Agency for the Assessment and Application of Technology. Laptiab building, Puspiptek Serpong Area, South Tangerang, Banten, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratory of Biotechnology, Agency for the Assessment and Application of Technology, Puspiptek Serpong Area, South Tangerang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Faculty of Pharmacy, Pancasila University. Srengseng Sawah Street, South Jakarta, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Nusaibah Zahratunnisa</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Arikadia Noviani</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Inhibition of Alpha-Glucosidase and Antioxidant Test of Stem Bark Extracts of Garcinia fruticosa Lauterb</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alpha-glucosidase</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">DPPH</style></keyword><keyword><style  face="normal" font="default" size="100%">Garcinia fruticosa Lauterb. Stem bark</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical screening</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://phcogj.com/fulltext/313</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">273-275</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Diabetes mellitus (DM) is one of the global health emergencies that characterized by high blood glucose levels (hyperglycemia). Type 2 DM is the most common type in diabetic populations. Inhibition of alphaglucosidase can ameliorate postprandial hyperglycemia that occurs in patients with type 2 DM. Adding antioxidants to the therapy of DM is intended to reduce complications caused by oxidative stress. Some species of &lt;em&gt;Garcinia&lt;/em&gt; have been proven to inhibit alpha-glucosidase and have antioxidant activity, but there is no research on &lt;em&gt;Garcinia fruticosa&lt;/em&gt; Lauterb. Therefore, the aims of this research were to determine the activity of &lt;em&gt;Garcinia fruticosa&lt;/em&gt; Lauterb. stem bark in inhibiting alpha-glucosidase and as an antioxidant. &lt;strong&gt;Methods:&lt;/strong&gt; In this research, the &lt;em&gt;Garcinia fruticosa&lt;/em&gt; Lauterb. stem bark was dried, grinded, and extracted by multistage maceration using n-hexane, ethyl acetate, and methanol. Inhibition of alpha-glucosidase test has been done &lt;em&gt;in vitro&lt;/em&gt; on concentrated extracts and measured by microplate reader at 400 nm. The antioxidant test has been done using DPPH scavenging method and was measured by microplate reader at 519 nm.&lt;strong&gt; Results:&lt;/strong&gt; Ethyl acetate extract is the most active extract for both test. IC&lt;sub&gt;50&lt;/sub&gt; values for inhibition of alpha-glucosidase test are 20.18 &amp;mu;g/mL that is more active than standard (acarbose) which has IC&lt;sub&gt;50&lt;/sub&gt; value 141.55 &amp;mu;g/mL. Meanwhile, IC&lt;sub&gt;50&lt;/sub&gt; value from an antioxidant test is 8.93 &amp;mu;g/mL that is not more active than standard (quercetin) which has IC&lt;sub&gt;50&lt;/sub&gt; value 2.51 &amp;mu;g/mL. &lt;strong&gt;Conclusion:&lt;/strong&gt; Phytochemical screening shows that the ethyl acetate extract contains alkaloids, flavonoids, glycosides, saponins, and tannins.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">273</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Nusaibah Zahratunnisa, Berna Elya*, Arikadia Noviani &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmacognosy- Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Kampus Baru UI Depok, 16424, Depok, INDONESIA.&lt;/p&gt;</style></auth-address></record></records></xml>