<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">T A Faiz T Anuar</style></author><author><style face="normal" font="default" size="100%">Azlini Ismail</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Southeast Asian Medicinal Plants with Angiotensin Converting Enzyme (ACE) Inhibition Properties</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">ACE</style></keyword><keyword><style  face="normal" font="default" size="100%">Angiotensin-converting enzyme</style></keyword><keyword><style  face="normal" font="default" size="100%">Antihypertensive</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plants</style></keyword><keyword><style  face="normal" font="default" size="100%">Southeast Asia</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1429-1439</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; This article aims to provide a summary of medicinal plants in the Southeast Asian countries that have an angiotensin-converting enzyme (ACE) inhibitory activity that is therapeutically useful for treating hypertension. &lt;strong&gt;Methods:&lt;/strong&gt; This review paper is a result of extensive searches via electronic database platforms, including Pubmed, Google Scholar, Scopus, and Science Direct with the keyword search terms: ACE enzyme, Southeast Asia countries, plants, and extracts. &lt;strong&gt;Results:&lt;/strong&gt; Thirty-four articles on ACE inhibition activity of 76 Southeast Asian medicinal plants were found and further reviewed. Several plants from Malaysia &lt;em&gt;(Chassalia curviflora, Citrus hystrix, Murraya koenigii, Senna garrettiana), Indonesia (Gnetum Gnemon, Momordica charantia, Nasturtium officinale, Peperomia pellucida, Pereskia saccharose)&lt;/em&gt;, and Thailand (Mammea siamensis) were found to exhibit strong ACE inhibitory activity in vitro. Bioactive compounds such as 3’,4’, dihydroxy-3-5 dimethoxy flavone-7-O- β-rhamnose and quercetin-3-O-glucoside showed the highest potency in exhibiting the ACE inhibition activity in this review.&lt;strong&gt; Conclusions:&lt;/strong&gt; This review suggests for an in-depth investigation on the potent crude extracts for the potential development of complementary herbal medicines as well as on the potent ACE inhibitor compounds for further development as new ACE inhibitor candidates for hypertension therapy.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1429</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;T. A. Faiz T. Anuar&lt;sup&gt;1&lt;/sup&gt;, Azlini Ismail&lt;sup&gt;2,&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Chemistry, Kulliyyah of Science, International Islamic University Malaysia, 25200 Kuantan, Pahang, MALAYSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Fundamental Dental and Medical Sciences, Kulliyyah of Dentistry, International Islamic University Malaysia, 25200 Kuantan, Pahang, MALAYSIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Anies Monica Adhitia</style></author><author><style face="normal" font="default" size="100%">Alisa Nur Octaviani</style></author><author><style face="normal" font="default" size="100%">Rissyelly</style></author><author><style face="normal" font="default" size="100%">Katrin Basah</style></author><author><style face="normal" font="default" size="100%">Abdul Mun’im</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of Gamma Irradiation on Angiotensin Converting Enzyme Inhibition, Antioxidant Activity, Total Phenolic Compound and Total Flavonoid of Peperomia pellucida Herbs Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">ACE</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Gamma-irradiation</style></keyword><keyword><style  face="normal" font="default" size="100%">Peperomia pellucida</style></keyword><keyword><style  face="normal" font="default" size="100%">Total flavonoids</style></keyword><keyword><style  face="normal" font="default" size="100%">total phenolic</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://phcogj.com/fulltext/308</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">244-248</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; &lt;em&gt;Peperomia pellucida&lt;/em&gt; L. Kunth has been reported to have some biological activities such as antihypertensive and antioxidants. Herbal materials susceptible to contamination during processing and storage which can shortens their shelf life. Gamma-irradiation has been used as a method for preservation. &lt;strong&gt;Methods:&lt;/strong&gt; This research aimed to analyze the effect of gamma-irradiation on inhibition activity of angiotensin converting enzyme (ACE), antioxidant activity, total phenol content, total flavonoid, and thin layer chromatography profiles of &lt;em&gt;P. pellucida&lt;/em&gt; L. Herbs extract. The extract was irradiated with 60Co gamma rays at 2.5; 5; 7.5; dan 10 kGy. &lt;strong&gt;Results:&lt;/strong&gt; Irradiation up to 10 kGy did not change ACE inhibitory activity and TLC profile. No significant differences were noted in the inhibition activity of ACE and the type of chromatogram profiles between non-irradiated extract and irradiated extracts up to a dose of 10 kGy while total flavonoids showed a significant decrease. In addition, total phenolic content and antioxidant activity showed a significant increase of extracts were irradiated up to 5 kGy and decrease at dose 7,5 kGy and 10 kGy. Gamma-irradiation up to 10 kGy didn&amp;rsquo;t affect the activity of ACEinhibitor &lt;em&gt;in-vitro&lt;/em&gt; while significant difference (P &amp;lt;0.05) of antioxidant activity, total flavonoids and phenolic content of the extract &lt;em&gt;P. Pellucida&lt;/em&gt;. &lt;strong&gt;Conclusion:&lt;/strong&gt; In conclusion, gamma - irradiation can be used as a preservation method for ethanol extract &lt;em&gt;P. Pellucida&lt;/em&gt; L. Kunth herbs.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">244</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Anies Monica Adhitia, Alisa Nur Octaviani, Rissyelly, Katrin Basah, Abdul Mun&amp;rsquo;im* &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmacognosy- Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Kampus Baru UI Depok 16424, Depok, Indonesia.&amp;nbsp;&lt;/p&gt;</style></auth-address></record></records></xml>