<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Honnesh NH</style></author><author><style face="normal" font="default" size="100%">Santanu Saha</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Evaluation of Antioxidant Activity and Flavonoid and Phytocompounds Content in Pongamia Pinnata Seed</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">DPPH</style></keyword><keyword><style  face="normal" font="default" size="100%">FRAP</style></keyword><keyword><style  face="normal" font="default" size="100%">GCMS</style></keyword><keyword><style  face="normal" font="default" size="100%">Karanjin</style></keyword><keyword><style  face="normal" font="default" size="100%">Pongamia pinnata</style></keyword><keyword><style  face="normal" font="default" size="100%">PPEAF</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">6</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Pongamia pinnata is a woody shrub and tree found in entire India mainly in dry areas. The seeds of P. pinnata are collected and traditionally oil is extracted and used to kill helminthes. The plant is a remedy for skin diseases, wound, rheumatism &amp;amp; ulcers and also as biofuel, green manure and fodder. This study is an attempt to know antioxidant activity of particular fraction which is having antifungal activity and flavonoid and fatty acids content which is responsible for the same. &lt;strong&gt;Materials and methods:&lt;/strong&gt; In this investigation, an effort was made to know the antioxidant activity of PPEAF by DPPH assay, FRAP assay and H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt; assay methods and Optimization of mobile phase by TLC method and supporting major flavonoid content quantification by HPTLC method &lt;strong&gt;Results:&lt;/strong&gt; The result shown the ethyl acetate fraction has significant antioxidant activity of IC&lt;sub&gt;50&lt;/sub&gt; value of&lt;strong&gt; 212.09&lt;/strong&gt; (DPPH assay), &lt;strong&gt;235.87&lt;/strong&gt; (FRAP assay) and &lt;strong&gt;268.62&lt;/strong&gt; (H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt; assay). The TLC method optimum mobile phase was found to be Toluene: ethyl acetate (7:3). The standard flavonoids used are Karanjin, Gallic acid and Quercetin. &lt;strong&gt;Conclusion:&lt;/strong&gt; The HPTLC method results shown PPEAF was found to contain 1.465% Karanjin. GCMS result shown the PPEAF contain 13 phytocompounds in which Octadec-9-enoic acid at retention time 22.356 was found to be abundant.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Honnesh NH&lt;sup&gt;1&lt;/sup&gt;, Santanu Saha&lt;sup&gt;2*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacognosy, Nitte College of Pharmaceutical Sciences, 6429, NITTE Campus, Govindapura, Gollahalli, Yelahanka, Bangalore - 560 064, Karnataka, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy, NGSM Institute of Pharmaceutical Sciences, Nitte (Deemed to be University), Panner, Deralakatte, Mangaluru-575018, Karnataka, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ankita Mridha</style></author><author><style face="normal" font="default" size="100%">Priya K Gopal</style></author><author><style face="normal" font="default" size="100%">Santanu Paul</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Screening Data Reveals that Spirogyra triplicata, a Fresh Water Algae Induces Robust Anti-Proliferative Activity Against A549 Cells</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">A549</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-proliferative</style></keyword><keyword><style  face="normal" font="default" size="100%">GCMS</style></keyword><keyword><style  face="normal" font="default" size="100%">Spirogyra triplicata</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">569-577</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Algae comprise a promising source of novel components with potent therapeutic agents. In particular, algae have been considered as a potential source of new bioactive compounds. The antioxidant data of our previous study with six different algal methanolic extract reveals the presence of high antioxidant, total phenol content and total flavonoid content in &lt;em&gt;Spirogyra triplicata. &lt;/em&gt;Thus, we further focused on screening the anti-proliferative activity of six different green algae on five different cancer cell lines like MCF7, A549, HEPG2, REH, MOLT4.&lt;strong&gt; Methods:&lt;/strong&gt; To fulfill our aim we performed MTT assay for testing anti-proliferative activity and DAPI staining for observing nuclear morphology. We also looked into the metabolomic profiling of &lt;em&gt;Spirogyra triplicata&lt;/em&gt; by GC-MS chemometric study. &lt;strong&gt;Results:&lt;/strong&gt; The result indicates that after 24 hours of treatment with methanolic extract of&lt;em&gt; Spirogyra triplicata &lt;/em&gt;A549 was the most sensitive cell line with IC&lt;sub&gt;50 &lt;/sub&gt;value of 24.07 ± 1.09 μg/ml. Followed by&lt;em&gt; Rhizoclonium fontinale&lt;/em&gt; and &lt;em&gt;Hydrodictyon reticulatum&lt;/em&gt; with IC&lt;sub&gt;50 &lt;/sub&gt;value of 25.97 ± 1.94 μg/ml and 32.50 ± 1.97 μg/ml respectively. The HEPG2 cell line was the second most sensitive cell line against&lt;em&gt; S. triplicata &lt;/em&gt;with IC&lt;sub&gt;50&lt;/sub&gt; value of 30.20 ± 1.45 μg/ml. The MOLT4 cell line was detected as most resistant cell line against the green algal extract in this study. Though the methanolic extracts of six green algae showed maximum to moderate anti-proliferative activity on different cancer cell line but no significantly affect on normal PBMC was observed. Nuclear fragmentation was observed in a dose dependent fashion by DAPI staining on A549 cells treated with methanolic extract of &lt;em&gt;Spirogyra triplicata. &lt;/em&gt;We further looked into the chemo profiling of&lt;em&gt; Spirogyra triplicata &lt;/em&gt;by GCMS analysis. The result of GC-MS clearly indicates presence of nineteen major components and twenty-three minor components which have more or less bioactivity and would help in therapeutics in future. &lt;strong&gt;Conclusions:&lt;/strong&gt; In brief this study indicates for the first time that green algae&lt;em&gt; Spirogyra triplicata &lt;/em&gt;induces anti-proliferative activity specifically against A549 cell but not in normal PBMC. It can be concluded that&lt;em&gt; Spirogyra triplicata&lt;/em&gt; holds a great promise as a good repository of anti cancer compounds which may be used in future drug discovery.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">569</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ankita Mridha, Priya K Gopal, Santanu Paul* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Laboratory of Cell and Molecular Biology, Department of Botany, University Of Calcutta, 35 Ballygunge Circular Road, Kolkata, West Bengal 700019, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Krishnaprasad Ganapati Koorse</style></author><author><style face="normal" font="default" size="100%">Sujith Samraj</style></author><author><style face="normal" font="default" size="100%">Preethy John</style></author><author><style face="normal" font="default" size="100%">Priya Manakkulaparambil Narayanan</style></author><author><style face="normal" font="default" size="100%">Devi SS</style></author><author><style face="normal" font="default" size="100%">Usha PTA</style></author><author><style face="normal" font="default" size="100%">Surya Sunilkumar</style></author><author><style face="normal" font="default" size="100%">Gleeja VL</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anthelmintic Activity of Fruit Extract and Fractions of Piper longum L. In vitro</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adulticidal</style></keyword><keyword><style  face="normal" font="default" size="100%">GCMS</style></keyword><keyword><style  face="normal" font="default" size="100%">IC50</style></keyword><keyword><style  face="normal" font="default" size="100%">Larvicidal</style></keyword><keyword><style  face="normal" font="default" size="100%">Ovicidal</style></keyword><keyword><style  face="normal" font="default" size="100%">Piper longum.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/487</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">333-340</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;The present study was aimed to assess the &lt;em&gt;in vitro&lt;/em&gt; ovicidal, larvicidal and adulticidal activity of methanolic extract and its fractions from fruits of &lt;em&gt;Piper longum&lt;/em&gt; against strongyle ova, larvae and adult amphistomes respectively. The fruits of &lt;em&gt;P. longum&lt;/em&gt; was identified and the accession number 006 was obtained. The phytochemical analysis revealed the presence of tannins, flavonoids, glycosides, phenolics, diterpenes and triterpenes in extract and fractions of &lt;em&gt;P. longum&lt;/em&gt;. The extract and fractions were diluted serially in 6.25 per cent tween 80 to obtain concentrations of 500, 250, 125, 62.5, 31.25, 15.63, 7.81, 3.91 and 1.95 mg/mL. Ivermectin and thiabendazole at 10 &amp;mu;g/mL acted as positive controls and 6.25 per cent tween 80 as negative control. The methanolic extract was highly active against ova with IC&lt;sub&gt;50&lt;/sub&gt; of 0.026 mg/mL. The n-hexane fraction was potent in inducing larval mortality with IC&lt;sub&gt;50&lt;/sub&gt; of 1.383 mg/mL while chloroform fraction inhibited larval migration with IC&lt;sub&gt;50&lt;/sub&gt; of 1.796 mg/mL. Amphistomes were highly sensitive for methanolic extract of &lt;em&gt;P. longum&lt;/em&gt; which possessed IC&lt;sub&gt;50&lt;/sub&gt; of 5.493 mg/mL Based on IC&lt;sub&gt;50&lt;/sub&gt; values, the methanolic extract was found to be most potent while chloroform fraction was effective against ova, larvae and also adults. GCMS analysis of potent methanolic extract revealed the presence of piperidinone, hydrocinnamic acid, ethylhexahydro azepine, methyleugenol, hexadecanoic acid and caryophyllene oxide which may have contributed for the anthelmintic activity. The acute oral toxicity study revealed mild vascular changes in liver. From the present study, it can be concluded that chloroform fraction of &lt;em&gt;P. longum&lt;/em&gt; possessed maximum broad spectrum anthelmintic activity comparable to controls.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">333</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Krishnaprasad Ganapati Koorse&lt;sup&gt;1&lt;/sup&gt;*, Sujith Samraj&lt;sup&gt;1&lt;/sup&gt;, Preethy John&lt;sup&gt;1&lt;/sup&gt;, Priya Manakkulaparambil Narayanan&lt;sup&gt;2&lt;/sup&gt;, Devi SS&lt;sup&gt;3&lt;/sup&gt;, Usha PTA&lt;sup&gt;1&lt;/sup&gt;, Surya Sunilkumar&lt;sup&gt;1&lt;/sup&gt;, Gleeja VL&lt;sup&gt;4 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Veterinary Parasitology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;3Department of Veterinary Pathology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Statistics, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Tom Mathew Kalappurayil</style></author><author><style face="normal" font="default" size="100%">Benny Pulinilkkumthadathil Joseph</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review of Pharmacognostical Studies on Moringa oleifera Lam. flowers</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bioactivity</style></keyword><keyword><style  face="normal" font="default" size="100%">Bioassay</style></keyword><keyword><style  face="normal" font="default" size="100%">Extracts</style></keyword><keyword><style  face="normal" font="default" size="100%">Flower</style></keyword><keyword><style  face="normal" font="default" size="100%">GCMS</style></keyword><keyword><style  face="normal" font="default" size="100%">Moringa</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemicals</style></keyword><keyword><style  face="normal" font="default" size="100%">Therapeutic</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2016</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">/files/PJ-9-3/10.5530pj.2017.1.1</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">1-7</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align:justify&quot;&gt;&lt;em&gt;Moringa oleifera&lt;/em&gt; Lam. of the family Moringaceae, popularly called &amp;lsquo;miracle tree&amp;rsquo; is a native of sub Himalayan tracts of Northern India and is widely cultivated in tropical and subtropical regions. Research on Moringa mainly pivoted around its leaves and seeds because of their immense nutraceutical potential but recently there is a greater interest in flowers too, mostly inspired by the positive outcomes of several pharmacognostical studies on flowers. Moringa flower is a rich reservoir of bioactive phytochemicals and crude flower extracts showed promising antibacterial, antifungal, anti larval, antioxidant, anti inflammatory and anticancer properties. This review concisely presents the various phytochemicals identified and isolated as well as the various bioassays employed to validate the therapeutic potential of flower. It is prepared after a detailed search on Google scholar. Reports on &lt;em&gt;Moringa oleifera&lt;/em&gt; flower were sorted and tabulated based on the bioassays performed and solvents used for extraction. A grading pattern is adopted for comparing efficiency of different extracts in eliciting bioactivities. Many of these studies are at the preliminary stage but two of them present advanced mechanisms. First is the presence of a proteinaceous larvicidal compound &amp;lsquo;MoFTI&amp;rsquo; in the flower capable of inhibiting larval trypsin of &lt;em&gt;Aedes aegypti&lt;/em&gt;. The second describes flower extract&amp;rsquo;s anti inflammatory mechanism effecting via NF-KB pathway and consequent suppression of inflammatory mediators&amp;rsquo; activation, but short of identifying lead compound/compounds behind this effect. Thus authors suggest further studies to elucidate the detailed mechanisms, identify and isolate the active compound or compounds of synergism behind the many therapeutic potential of the Moringa flower extracts.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">1</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Tom Mathew Kalappurayil&lt;sup&gt;*&lt;/sup&gt;, Benny Pulinilkkumthadathil Joseph&lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Zoology, St Thomas College, Pala PIN 686574, Kottayam district, Kerala, INDIA&lt;/p&gt;
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