<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ramasamy Manikandan</style></author><author><style face="normal" font="default" size="100%">Arumugam Vijaya Anand</style></author><author><style face="normal" font="default" size="100%">Sampath Kumar</style></author><author><style face="normal" font="default" size="100%">Pushpa</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Phytochemical and In vitro Antidiabetic Activity of Psidium Guajava Leaves</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alpha amylase</style></keyword><keyword><style  face="normal" font="default" size="100%">Alpha glucosidase</style></keyword><keyword><style  face="normal" font="default" size="100%">P. guajava</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June/2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">392-394</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The present investigation includes the preliminary screening of phytochemicals and evaluation of &lt;em&gt;in vitro&lt;/em&gt; antidiabetic activity of &lt;em&gt;Psidium guajava&lt;/em&gt; leaves extracts. &lt;strong&gt;Materials&lt;/strong&gt; &lt;strong&gt;and Methods:&lt;/strong&gt; Plant material was subjected to the extraction preparation by soxhlet apparatus by using various solvents such as aqueous, ethanol, chloroform, petroleum ether and hexane. The various kinds of phytochemicals were detected and then &lt;em&gt;in vitro&lt;/em&gt; antidiabetic activity of &lt;em&gt;P. guajava &lt;/em&gt;were detected by using alpha amylase and alpha glucosidase enzyme in an &lt;em&gt;in vitro&lt;/em&gt; model. &lt;strong&gt;Results:&lt;/strong&gt; The study reveals the presence of phytochemicals such as carbohydrate, tannin, flavonoids, phenols etc., Among the various extracts the aqueous and ethanolic extracts which contains the large number of phytoconstituents. The &lt;em&gt;P. guajava &lt;/em&gt;leaves has been successfully inhibited both the enzymes in an &lt;em&gt;in vitro&lt;/em&gt; model. The aqueous extracts of &lt;em&gt;P. guajava&lt;/em&gt; leaves inhibited the alpha amylase and alpha glucosidase enzymes as 72.1% and 74.8% respectively. The ethanolic extract of &lt;em&gt;P. guajava &lt;/em&gt;leaves inhibited the alpha amylase and alpha glucosidase enzymes as 97.5% and 91.8% respectively. &lt;strong&gt;Conclusion:&lt;/strong&gt; From the results obtained in the current studies, the &lt;em&gt;P. guajava &lt;/em&gt;leaves have a prominent antidiabetic property in an &lt;em&gt;in vitro&lt;/em&gt; model and further studies can be carried out in an &lt;em&gt;in vivo&lt;/em&gt; model and the isolation of activie compound from&lt;em&gt; P. guajava &lt;/em&gt;leaves extract is needed&lt;em&gt;.&lt;/em&gt;&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">392</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ramasamy Manikandan&lt;sup&gt;1&lt;/sup&gt;, Arumugam Vijaya Anand&lt;sup&gt;2&lt;/sup&gt;, Sampath Kumar&lt;sup&gt;3&lt;/sup&gt; and Pushpa&lt;sup&gt;4 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of BioChemistry, M.I.E.T Arts and Science College, Trichirappalli-620 007, Tamil Nadu, INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore-641 046, Tamil Nadu, INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Chemistry and Biosciences, SASTRA University, Kumbakonam&amp;ndash;612 001, Tamil Nadu, INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Microbiology, Cauvery College for Women, Tiruchirappalli&amp;ndash;620 018, Tamil Nadu, INDIA.&lt;/p&gt;
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