<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Patcharin Singdam</style></author><author><style face="normal" font="default" size="100%">Anussara Kamnate</style></author><author><style face="normal" font="default" size="100%">On-Anong Somsap</style></author><author><style face="normal" font="default" size="100%">Ruhainee Tohkayomatee</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Comparative Phytochemical, Antioxidant, and Antibacterial Study of Different Solvent Extracts of Cissus hastata Leaves</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Cissus hastata</style></keyword><keyword><style  face="normal" font="default" size="100%">Leaves</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">511-519</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Plants have long been utilized in traditional medicine for treating a variety of diseases. Plant-derived extracts are a rich source of phytochemicals with documented antibacterial and antioxidant properties. &lt;strong&gt;Objective:&lt;/strong&gt; This study aimed to investigate and compare the phytochemical profiles, antioxidant capacities, and antibacterial activities of various crude extracts from the leaves of &lt;em&gt;Cissus hastata.&lt;/em&gt; &lt;strong&gt;Methods: &lt;/strong&gt;Leaf extracts of &lt;em&gt;C. hastata&lt;/em&gt; were prepared using hexane (Hex), ethyl acetate (EtOAc), 95% ethanol (EtOH), and 50% ethanol (AqE). These extracts were analyzed for preliminary phytochemical constituents, total phenolic content (TPC), total flavonoid content (TFC), antioxidant activity (DPPH, ABTS, and FRAP assays), and antibacterial activity against five bacterial strains: Staphylococcus aureus (TISTR 517), methicillin-resistant &lt;em&gt;Staphylococcus aureus&lt;/em&gt; (MRSA 142)&lt;em&gt;, Bacillus cereus&lt;/em&gt; (ATCC 11778), &lt;em&gt;Escherichia coli &lt;/em&gt;(ESBL 182), and &lt;em&gt;Salmonella typhimurium &lt;/em&gt;(TISTR 292). &lt;strong&gt;Results: &lt;/strong&gt;Phytochemical screening of different solvent extracts of &lt;em&gt;C. hastata&lt;/em&gt; leaves revealed the presence of diverse bioactive compounds. The EtOAc and AqE extracts exhibited the highest TPC (65.31 ± 1.85 and 61.45 ± 3.34 mg GAE/g extract, respectively) (&lt;em&gt;p&lt;/em&gt; &amp;lt; 0.05). In contrast, the EtOH extract showed the highest TFC (29.92 ± 3.42 mg QE/g extract) (p &amp;lt; 0.05). The EtOH and AqE extracts also demonstrated the strongest antioxidant activities in the DPPH (IC50: 307.07 ± 7.18 μg/mL and 316.86 ± 11.78 μg/mL), ABTS (IC50: 160.21 ± 5.43 μg/mL and 208.45 ± 3.84 μg/ mL) (p &amp;lt; 0.05), and FRAP (4.69 ± 0.08 and 4.96 ± 0.07 mM FeSO4/mg extract) assays. The antibacterial activity was observed exclusively against Gram-positive bacteria. Among all the extracts, the AqE extract at a concentration of 100 mg/mL exhibited significant antibacterial effects against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, and Bacillus cereus, with zones of inhibition measuring 15.43 ± 0.46 mm, 14.76 ± 0.58 mm, and 15.66 ± 1.04 mm, respectively. &lt;strong&gt;Conclusion:&lt;/strong&gt; Ethanol-based extracts of&lt;em&gt; C. hastata&lt;/em&gt; leaves demonstrate high antioxidant and antibacterial activities and represent a promising source of bioactive compounds for developing natural therapeutic agents.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">511</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Patcharin Singdam&lt;sup&gt;1*&lt;/sup&gt;, Anussara Kamnate&lt;sup&gt;2&lt;/sup&gt;, On-Anong Somsap&lt;sup&gt;3&lt;/sup&gt;, Ruhainee Tohkayomatee&lt;sup&gt;1&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, Faculty of Medicine, Princess of Naradhiwas University, Narathiwat 96000, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Anatomy, Faculty of Medicine, Princess of Naradhiwas University, Narathiwat 96000, THAILAND&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Biochemistry, Faculty of Medicine, Princess of Naradhiwas University, Narathiwat 96000, THAILAND.&lt;/p&gt;
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