<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dinesh Kumar Yadav</style></author><author><style face="normal" font="default" size="100%">Mohammed Ali</style></author><author><style face="normal" font="default" size="100%">Ashoke Kumar Ghosh</style></author><author><style face="normal" font="default" size="100%">Babita Kumar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Isolation of flavonoid from Abies webbiana leaves and its activity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">1-H NMR</style></keyword><keyword><style  face="normal" font="default" size="100%">Abies webbiana</style></keyword><keyword><style  face="normal" font="default" size="100%">CCl4.</style></keyword><keyword><style  face="normal" font="default" size="100%">Cisplatin</style></keyword><keyword><style  face="normal" font="default" size="100%">Quercetin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June/2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">341-345</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;Abies webbiana &lt;/em&gt;commonly known as Talispatra in Bengali and Hindi, Talispatram in Sanskrit and Indian Silver Fir in English. This is a large, tall, evergreen tree occurring in the Himalayan region from Kashmir to Assam in India. It comes under the Family: Pinaceae. The present study was designed for isolation of flavonoid from ethyl acetate extract of &lt;em&gt;A. webbiana&lt;/em&gt; leaves and assessed their toxic effect on liver and kidney. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; The isolation of flavonoid using different chromatographic methods (thin layer and column chromatography). The isolated flavonoid was identified; Structures and chemical bonds were analyzed by using MP, FTIR, 1-H NMR and MS spectral analysis. Effect of flavonoid on liver and kidney was assessed by inducing (0.1 ml/kg) CCl&lt;sub&gt;4&lt;/sub&gt; (i.p.) and (6 mg/kg) Cisplatin (i.p.) respectively measured by biochemical marker of liver and kidney. &lt;strong&gt;Results and Discussion: &lt;/strong&gt;It was identified that isolated compound was as 4&amp;rsquo;-hydroxy quercetin on the basis of FTIR, 1-H NMR and MS spectral analysis. Isolated flavonoid reduced the increased biochemical marker (BM) of liver and kidney. The BM was increased by inducing CCl&lt;sub&gt;4&lt;/sub&gt; and Cisplatin respectively. &lt;strong&gt;Conclusion:&lt;/strong&gt; Isolated compound was 4&amp;rsquo;-methoxy quercetin and significantly protect the liver and kidney.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">341</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Dinesh Kumar Yadav&lt;sup&gt;1&lt;/sup&gt;*, Mohammed Ali&lt;sup&gt;2&lt;/sup&gt;, Ashoke Kumar Ghosh&lt;sup&gt;3&lt;/sup&gt;, Babita Kumar&lt;sup&gt;1&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;College of Pharmacy, Shree Ganpati Institute of Technology, Ghaziabad (U.P.), INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Pharmacognosy &amp;amp; Phytochemistry, Phytochemistry Research Laboratory, Faculty of Pharmacy, Jamia Hamdard, Hamdard Nagar, New Delhi 110062, INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;School of Pharmaceutical Sciences, IFTM University, Moradabad (U.P.), INDIA.&lt;/p&gt;
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