<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Pradeep Kumar Sharma</style></author><author><style face="normal" font="default" size="100%">Vijender Singh</style></author><author><style face="normal" font="default" size="100%">Mohammed Ali</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Chemical Composition and Antimicrobial Activity of Fresh Rhizome Essential Oil of Zingiber Officinale Roscoe</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal,</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Chemical composition</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oil</style></keyword><keyword><style  face="normal" font="default" size="100%">GC-MS analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Zingiber officinale.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">185-190</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;Zingiber officinale &lt;/em&gt;Roscoe (Zingiberaceae) is a rhizomatous perennial herb found in tropical Asia. It is extensively used worldwide as a spice, flavoring agent and herbal remedy for cold, throat and chest&amp;nbsp;infections and cough. The present study was carried out to analyse an essential oil from the fresh rhizomes of &lt;em&gt;Z. officinale &lt;/em&gt;of Ghaziabad region and to evaluate its antimicrobial activity. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;The fresh rhizomes were hydrodistilled to get the essential oil which was analysed by GC and GC-MS techniques. The oil was evaluated for antimicrobial activity by disc diffusion method. &lt;strong&gt;Results and Discussion: &lt;/strong&gt;The essential oil was characterized by high percentage of sesquiterpenes (66.66%), monoterpenes (17.28%) and aliphatic compounds (13.58%). The predominant sesquiterpene was zingiberene (46.71%) followed by valencene (7.61%), &amp;beta;-funebrene (3.09%) and selina-4(14),7(11)-diene (1.03%). The major monoterpenes were characterized as citronellyl &lt;em&gt;n&lt;/em&gt;-butyrate (19.34%), &amp;beta;-phellandrene (3.70%), camphene (2.59%) and &amp;alpha;-pinene (1.09%). The essential oil exhibited significant antimicrobial activity against &lt;em&gt;Bacillus subtilis, Staphylococcus aureus&lt;/em&gt;, &lt;em&gt;Escherichia&lt;/em&gt; &lt;em&gt;coli, Pseudomonas aeruginosa&lt;/em&gt;, &lt;em&gt;Candida albicans &lt;/em&gt;and &lt;em&gt;Aspergillus niger&lt;/em&gt;. &lt;strong&gt;Conclusion: &lt;/strong&gt;The essential oil mainly contained a large number of sesquiterpenes and monoterpenes and exhibited significant antimicrobial activity against pathogenic microorganisms.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">185</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align:justify&quot;&gt;&lt;strong&gt;Pradeep Kumar Sharma&lt;sup&gt;1&lt;/sup&gt;*, Vijender Singh&lt;sup&gt;2&lt;/sup&gt;, Mohammed Ali&lt;sup&gt;3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align:justify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacy, R V Northland Institute, Greater Noida, G B Nagar, U.P. 203207, INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align:justify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;B B S College of Pharmacy, Greater Noida, G B Nagar, U.P. 201306, INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align:justify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Phytochemistry Research Laboratory, Faculty of Pharmacy, Jamia Hamdard, Hamdard Nagar, New Delhi 110062, INDIA.&lt;/p&gt;
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