<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dadang Juanda</style></author><author><style face="normal" font="default" size="100%">Irda Fidrianny</style></author><author><style face="normal" font="default" size="100%">Komar Ruslan Wirasutisna</style></author><author><style face="normal" font="default" size="100%">Muhamad Insanu</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Evaluation of Xanthine Oxidase Inhibitory and Antioxidant Activities of Three Organs of Idat (Cratoxylum glaucum Korth.) and Correlation with Phytochemical Cont</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Cratoxylum glaucum</style></keyword><keyword><style  face="normal" font="default" size="100%">Xanthine oxidase inhibitory</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">971-976</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Idat (&lt;em&gt;Cratoxylum glaucum &lt;/em&gt;Korth.), belonging to the genus Cratoxylum, is known to contain xanthone, quinone, flavonoids, and other phenolic compounds. &lt;strong&gt;Objectives:&lt;/strong&gt; to analyze total phenolic, flavonoid, antioxidant activity, and inhibitory xanthine oxidase activities of leaves, stem, and cortex of idat. &lt;strong&gt;Methods: &lt;/strong&gt;Extraction of leaves, stem, and cortex of idat was carried out by reflux using n-hexane, ethyl acetate, and ethanol as a solvent. Antioxidant activity was tested by the DPPH method and calculated to get the antioxidant activity index (AAI). Determination of total phenolic and flavonoid levels by ultraviolet-visible spectrophotometry.&lt;strong&gt; Results:&lt;/strong&gt; Spectrophotometers measured the inhibitory activity on xanthine oxidase in 96-well plates with allopurinol as standard. Total phenolic and flavonoid content from &lt;em&gt;C. glaucum&lt;/em&gt; extracts varied from 6.62 to 48.77 g GAE/g extract and 1.54 - 25.96 g QE/100 g extract, respectively. The ethanol extracts of leaves, stem, and cortex were very strong antioxidant activity with Antioxidant Activity Index (AAI) values 3.89; 4.55; 10.50, meanwhile AAI of ascorbic acid and quercetin 9.46 and 14.81 respectively. The n-hexane of stem extract had a strong xanthine oxidase inhibitory activity with the IC&lt;sub&gt;50&lt;/sub&gt; was 36.64 μg/ml, while allopurinol was 5.02 μg/ml. &lt;strong&gt;Conclusions: &lt;/strong&gt;Total phenolic content contributed to antioxidant activity. Phenolic compounds in leaves extracts led to the xanthine oxidase inhibitory and antioxidant activities. The extract of &lt;em&gt;C. glaucum&lt;/em&gt; was active as an antioxidant and potentially an inhibitor of xanthine oxidase agents.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">971</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Dadang Juanda&lt;sup&gt;1,2&lt;/sup&gt;, Irda Fidrianny&lt;sup&gt;1&lt;/sup&gt;, Komar Ruslan Wirasutisna&lt;sup&gt;1&lt;/sup&gt;, Muhamad Insanu&lt;sup&gt;1,&lt;/sup&gt;*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Biology, School of Pharmacy, Bandung Institute of Technology, Bandung, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Pharmacy, Bhakti Kencana University, Bandung, INDONESIA.&lt;/p&gt;
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