<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">D. Sathis Kumar,</style></author><author><style face="normal" font="default" size="100%">David Banji,</style></author><author><style face="normal" font="default" size="100%">A. Harani,</style></author><author><style face="normal" font="default" size="100%">Ch. Pavan Kumar,</style></author><author><style face="normal" font="default" size="100%">JN. Ravi Varma</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Role of Boswellia ovalifoliolata Bal. Henry extract on high fat diet induced hypercholesterolemia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Boswellia Ovalifoliolata Bal. Henry</style></keyword><keyword><style  face="normal" font="default" size="100%">High Fat Diet</style></keyword><keyword><style  face="normal" font="default" size="100%">lipid profile</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">8th April 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">108-116</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; To evaluate the Antihypercholesterolemic effect of &lt;em&gt;Boswellia ovalifoliolata&lt;/em&gt; Bal. Henry extract by performing &lt;em&gt;in vivo&lt;/em&gt; studies and to check out its effects by evaluating parameters like food consumption, weight gain, fecal fat excretion, serum and liver lipid &amp;amp;biochemical profiles. Even the study includes confirmation of activity by the histopathological studies. &lt;strong&gt;Methods: &lt;/strong&gt;Animals were fed with cholesterol rich high fat diet. Food intake, Body weight and fecal fat excretion were measured. Serum and liver samples were analyzed for the estimation of lipid profiles and other biochemical parameters by using different kits. Histopathological study on liver, aorta, heart and adipose tissue was done to ensure the activity.&lt;strong&gt; Results:&lt;/strong&gt; The animal group administered with methanolic extract of the plant has shown decreased levels of TC, LDL, VLDL, TG, HDL+VLDL, VLDL+LDL, LDL/TC, AI, SGOT, SGPT and elevated levels of HDL, HDL/TC in a dose dependent manner significantly (p&amp;lt;0.01 &amp;amp; p&amp;lt;0.05). The evaluation of liver tissue of animal groups treated with herbal extract and standard had shown increased levels of SOD, GSH and Catalase, whereas levels of SGOT, SGPT, Total glucose, HMG-CoA, lipase, amylase and percentage of monaldehyde were decreased when compared with high fat diet fed rats. Body weight and Food intake in treated groups were significantly lower than that in model control. &lt;strong&gt;Conclusion:&lt;/strong&gt; It can be confered from the present studies that the &lt;em&gt;Boswellia ovalifoliolata&lt;/em&gt; Bal. Henry extract have strong activity against hypercholesterolemia and obesity suggesting a potential benefit as antihypercholesterolemic agent.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;key words&lt;/strong&gt;: &lt;em&gt;Boswellia ovalifoliolata&lt;/em&gt; Bal. Henry, High fat diet, Lipid profile, Histopathological studies.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;D. Sathis Kumar&lt;sup&gt;1,2*&lt;/sup&gt;, David Banji&lt;sup&gt;3&lt;/sup&gt;, A. Harani&lt;sup&gt;4&lt;/sup&gt;, Ch. Pavan Kumar&lt;sup&gt;1&lt;/sup&gt; and JN. Ravi Varma&lt;/strong&gt;&lt;sup&gt;&lt;strong&gt;4&lt;/strong&gt;&lt;/sup&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Aditya Institute of Pharmaceutical Sciences and Research, Surampalem, Andhra Pradesh, India-533437&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Jawaharlal Nehru Technical University, Hyderabad, Andhra Pradesh, India&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh, India-508001&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;A.U. College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, India-530003.&lt;/p&gt;</style></auth-address></record></records></xml>