<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Imane Zakariya</style></author><author><style face="normal" font="default" size="100%">Omar Elhamdaoui</style></author><author><style face="normal" font="default" size="100%">Zineb ibn lahmar Andaloussi</style></author><author><style face="normal" font="default" size="100%">Abdelhak Chergui</style></author><author><style face="normal" font="default" size="100%">El Amine Ajal</style></author><author><style face="normal" font="default" size="100%">Khalid Taghzouti</style></author><author><style face="normal" font="default" size="100%">Rachid Nejjari</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Acute Diuretic Activity of the Aqueous Ethanol Root Extract of Corrigiola telephiifolia Pourr. In Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Corrigiola telephiifolia</style></keyword><keyword><style  face="normal" font="default" size="100%">Diuretic activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Diuretic plants</style></keyword><keyword><style  face="normal" font="default" size="100%">Kaliuresis</style></keyword><keyword><style  face="normal" font="default" size="100%">Urine electrolytes</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1552-1558</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study was undertaken to justify and validate a very frequent traditional use of a very well-known and widely used plant by a large part of the Moroccan population. It’s about &lt;em&gt;Corrigiola telephiifolia&lt;/em&gt;, and the activity in question is the diuretic activity.&lt;strong&gt; Methods: &lt;/strong&gt;The aqueous ethanol root extract of&lt;em&gt; CMethods:orrigiola telephiifolia&lt;/em&gt; (200 mg/kg, 400 mg/kg, and 700 mg/kg) was orally administered to rats. The urinary excretion rate and pH, and electrolyte excretion were measured in the urine of saline-loaded rats. Negative control group received only an equivalent volume of distilled water, while the positive control groups received the diuretic drugs hydrochlorothiazide at dose 10 mg/kg. &lt;strong&gt;Results: &lt;/strong&gt;The results showed that hydrochlorothiazide induced significant diuresis and electrolytes excretion at 1, 6 and 24 h after the treatment. Both the higher doses of the extract produced a significant increase in urine volume than the control from the first hour until the end of observation. However, the lowest dose increased significantly only at 24 h after the treatment. With regard to the electrolyte excretion, the tested doses of CTRE which have shown a significant increase in Na&lt;sup&gt;+&lt;/sup&gt;, K&lt;sup&gt;+&lt;/sup&gt; and Cl&lt;sup&gt;-&lt;/sup&gt;excretion in comparison to normal control rats, are 400 and 700 mg/kg bw. &lt;strong&gt;Conclusion: &lt;/strong&gt;These findings collectively indicate that the extracts of&lt;em&gt; C. telephiifolia&lt;/em&gt; have a potential to induce diuresis markedly, and providing evidence, for its traditional use.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1552</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Imane Zakariya&lt;sup&gt;1,&lt;/sup&gt;* , Omar Elhamdaoui&lt;sup&gt;1&lt;/sup&gt;, Zineb ibn lahmar Andaloussi&lt;sup&gt;2&lt;/sup&gt;, Abdelhak Chergui&lt;sup&gt;1&lt;/sup&gt;, Al amine Ajlal&lt;sup&gt;1&lt;/sup&gt;, Khalid Taghzouti&lt;sup&gt;2&lt;/sup&gt;, Rachid Nejjari&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of pharmacognosy, faculty of medicine and pharmacy, University Mohammed V, BP 6203, RABAT, MOROCCO.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biology, faculty of science, University Mohammed V, BP: 1014, Rabat- MOROCCO.&lt;/p&gt;
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