<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Bokov DO</style></author><author><style face="normal" font="default" size="100%">Potanina OG</style></author><author><style face="normal" font="default" size="100%">Nikulin AV</style></author><author><style face="normal" font="default" size="100%">Shchukin VM</style></author><author><style face="normal" font="default" size="100%">Orlova VA</style></author><author><style face="normal" font="default" size="100%">Bagirova GB</style></author><author><style face="normal" font="default" size="100%">Kakhramanova SD</style></author><author><style face="normal" font="default" size="100%">Al- Khafaji H</style></author><author><style face="normal" font="default" size="100%">Balobanova NP</style></author><author><style face="normal" font="default" size="100%">Evgrafov AA</style></author><author><style face="normal" font="default" size="100%">Samylina IA</style></author><author><style face="normal" font="default" size="100%">Krasnyuk II</style></author><author><style face="normal" font="default" size="100%">Golubeva OA</style></author><author><style face="normal" font="default" size="100%">Kuleshova ES</style></author><author><style face="normal" font="default" size="100%">Moiseev DV</style></author><author><style face="normal" font="default" size="100%">Bessonov VV</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Modern Approaches to the Analysis of Kelp (Laminaria sp.) as Pharmacopoeial Herbal Drugs and Food Products</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">alginic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">Fucoidan</style></keyword><keyword><style  face="normal" font="default" size="100%">Iodine</style></keyword><keyword><style  face="normal" font="default" size="100%">Kelp</style></keyword><keyword><style  face="normal" font="default" size="100%">Laminaria japonica</style></keyword><keyword><style  face="normal" font="default" size="100%">Laminaria saccharina</style></keyword><keyword><style  face="normal" font="default" size="100%">Laminarin</style></keyword><keyword><style  face="normal" font="default" size="100%">Mannitol</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">929-937</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Currently, the chemical composition of&lt;em&gt; Laminaria&lt;/em&gt; J.V. Lamour. species is well studied; they have found applications in the food, cosmeceutical and pharmaceutical industries. The main groups of biologically active compounds are polysaccharides (alginic acid, laminarin, mannitol, fucoidan, and others) and minerals (iodine compounds, magnesium, potassium, calcium, iron) that are determined according to pharmacopoeial and All-Union State Standards requirements.&lt;strong&gt; Materials and Methods: &lt;/strong&gt;For data obtaining various types of search tools and engines such as Google, Google scholar, scientific literature (including Russian sources), normative documentation of Russian Federation (State Pharmacopoeia of Russian Federation IV edition, All-Union State Standards, and others) electronic databases such as e-Library, Scopus, Web of Science, Pubmed were used. &lt;strong&gt;Results:&lt;/strong&gt; In the course of this review study, a modern characteristic of the kelp thallus as a pharmaceutical, cosmeceutical, food substance of plant origin is presented. The data on the chemical composition, harvesting, and processing of raw materials are summarized. The standardization and safety issues of kelp thallus are considered taking into account modern pharmacopoeial and food international requirements. The approaches to the qualitative and quantitative analysis of biologically active compounds (polysaccharides, iodine) and the determination of safety indicators are studied. &lt;strong&gt;Conclusions:&lt;/strong&gt; The regulatory documentation that is used in the quality control of kelp needs to be finalized and updated. For pharmacopoeial analysis, all possible physicochemical methods (gravimetric, titrimetric, spectrophotometric) should be presented in the newly approved monograph. In this case, modern procedures should be developed, including HPLC with various types of detection (determination of the carbohydrates profile and polysaccharides, including methods with acid and enzyme hydrolysis). This will ensure the required level of quality, the safety of kelp (Laminaria) raw materials.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">929</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Bokov DO&lt;sup&gt;1,2,&lt;/sup&gt;*, Potanina OG&lt;sup&gt;3&lt;/sup&gt;, Nikulin AV&lt;sup&gt;3&lt;/sup&gt;, Shchukin VM&lt;sup&gt;4&lt;/sup&gt;, Orlova VA&lt;sup&gt;1&lt;/sup&gt;, Bagirova GB&lt;sup&gt;1&lt;/sup&gt;, Kakhramanova SD&lt;sup&gt;1,4&lt;/sup&gt;, Al-Khafaji H&lt;sup&gt;1&lt;/sup&gt;, Balobanova NP&lt;sup&gt;1&lt;/sup&gt;, Evgrafov AA&lt;sup&gt;1&lt;/sup&gt;, Samylina IA&lt;sup&gt;1&lt;/sup&gt;, Krasnyuk II&lt;sup&gt;1&lt;/sup&gt; (junior), Golubeva OA&lt;sup&gt;5&lt;/sup&gt;, Kuleshova ES&lt;sup&gt;6&lt;/sup&gt;, Moiseev DV&lt;sup&gt;7&lt;/sup&gt;, Bessonov VV&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Sechenov First Moscow State Medical University, 8 Trubetskaya St., bldg. 2, Moscow, 119991, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Federal Research Center of Nutrition, Biotechnology and Food Safety, 2/14 Ustyinsky pr., Moscow, 109240, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Рeoples’ Friendship University of Russia (RUDN University), 6, Miklukho-Maklaya Street, Moscow, 117198, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Federal State Budgetary Institution “Scientific Centre for Expert Evaluation of Medicinal Products”, 8/2 Petrovsky Boulevard, Moscow, 127051, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Murmansk State Technical University, 183010, str. Sportivnaya, 13, Murmansk, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Orel State University named after I.S. Turgenev, 95 Komsomolskaya st., Orel region, Orel, 302026, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Vitebsk State Medical University, 27, Frunze avenue, Vitebsk, 210062, BELARUS.&lt;/p&gt;
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