<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Pornpun Laovachirasuwan</style></author><author><style face="normal" font="default" size="100%">Wutthichart Fuangbangluang</style></author><author><style face="normal" font="default" size="100%">Atchariyaporn Phanichanaphan</style></author><author><style face="normal" font="default" size="100%">Issarapong Nasomroop</style></author><author><style face="normal" font="default" size="100%">Methin Phadungkit</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Development of Phyllanthus emblica Extract in Ethosomes for Hair Loss Prevention</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Entrapment efficiency</style></keyword><keyword><style  face="normal" font="default" size="100%">Ethosomes</style></keyword><keyword><style  face="normal" font="default" size="100%">Phyllanthus emblica</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">905-910</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Hair loss is not a serious health problem but leads to decreased self- confidence, personality, and psychological problems. According to Thai traditional medical wisdom, &lt;em&gt;Phyllanthus emblica &lt;/em&gt;has the property to prevent hair loss. Ethosomes are a drug delivery system, which can increase drug delivery to deep skin layers and enhance the effectiveness of the active ingredient.&lt;strong&gt; Objective: &lt;/strong&gt;This research aims to develop ethosomes of &lt;em&gt;Phyllanthus emblica&lt;/em&gt; extract with beneficial properties. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; &lt;em&gt;Phyllanthus emblica&lt;/em&gt; was extracted by a maceration method with 95% ethanol as a solvent. The total phenolic content of the extracts was determined using the Folin-Ciocalteu method. The antioxidation activity was evaluated by DPPH assay. Ethosomes were formulated by a cold method and their properties were observed. &lt;strong&gt;Results: &lt;/strong&gt;The results showed that the total phenolic content of &lt;em&gt;Phyllanthus emblica &lt;/em&gt;extract was 406.37±2.39 mg GAE/g extract. The IC&lt;sub&gt;50&lt;/sub&gt; of antioxidant activity was 7.05±0.17 μg/ml. Ethosomes with 0.03% of &lt;em&gt;Phyllanthus emblica &lt;/em&gt;extract, 2% of soya phosphatidylcholine, and 20% of ethanol had the highest percentage of entrapment efficiency (65.26%±1.80%). The ethosomes of &lt;em&gt;Phyllanthus emblica &lt;/em&gt;extract was the spherical shape and white colloid. The particle size, polydispersity index, zeta potential, and pH of ethosomes were 0.43±0.00 μm, 0.44±0.03, -10.40±0.28 mV, and 4.06±0.03, respectively. &lt;strong&gt;Conclusion: &lt;/strong&gt;The ethosomes of &lt;em&gt;Phyllanthus emblica&lt;/em&gt; extract had good properties and area possible alternative product for hair loss prevention.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">905</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Pornpun Laovachirasuwan*, Wutthichart Fuangbangluang, Atchariyaporn Phanichanaphan, Issarapong Nasomroop, Methin Phadungkit &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Faculty of Pharmacy, Mahasarakham University, Kantarawichai District, Mahasarakham 44150, THAILAND&lt;/p&gt;
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