<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Lokot Donna Lubis</style></author><author><style face="normal" font="default" size="100%">Muhammad Fidel Ganis Siregar</style></author><author><style face="normal" font="default" size="100%">Farhat</style></author><author><style face="normal" font="default" size="100%">Iqbal Pahlevi Adeputra Nasution</style></author><author><style face="normal" font="default" size="100%">Dedy Syahrizal</style></author><author><style face="normal" font="default" size="100%">Kamal Basri Siregar</style></author><author><style face="normal" font="default" size="100%">Putri Chairani Eyanoer</style></author><author><style face="normal" font="default" size="100%">Ichwanul Adenin</style></author><author><style face="normal" font="default" size="100%">Muhammad Rusda</style></author><author><style face="normal" font="default" size="100%">Mustafa M. Amin</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Phytochemical Screening, Thin Layer Chromatography and Fourier Transform Infra-Red Spectroscopy Analysis of Eleutherine Bulbous (Mill.) Urb Bulb Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Dayak onion</style></keyword><keyword><style  face="normal" font="default" size="100%">Eleutherine bulbous</style></keyword><keyword><style  face="normal" font="default" size="100%">Extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Fraction</style></keyword><keyword><style  face="normal" font="default" size="100%">FTIR</style></keyword><keyword><style  face="normal" font="default" size="100%">TLC</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">88-93</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Many traditional medicinal plants were studied for their phytochemical components. Dayak onions (Eleutherine bulbous (Mill.) Urb) is one of traditional medicinal plant in Indonesia. Analysis of the phytochemical compounds in the extract of the plant would help in determining various biological activities of the plant. &lt;strong&gt;Objective:&lt;/strong&gt; This study was primarily aimed to identify the phytochemical profile of Dayak onions extract and its fractions. &lt;strong&gt;Methods: &lt;/strong&gt;The Dayak onion bulbs were collected from Pancur Batu District, North Sumatra Province, Indonesia. Multiple solvents used to for extraction and analysis of phytochemical compound by chemical reactions, thin layer chromatography (TLC) profiling, and Fourier Transform Infrared Spectrophotometer (FTIR) profiling. &lt;strong&gt;Results:&lt;/strong&gt; The phytochemical screening of Dayak onions ethanol extract showed it contained alkaloids, flavonoids, glycosides, tannins, and triterpenes/ steroids. The n-hexane fraction contained flavonoids and triterpenes/steroids, while the ethyl acetate fraction contains flavonoids and glycosides. The water fraction contained alkaloids, flavonoids, glycosides and tannins. By TLC profiling, the bioactive compounds in ethanol extract of the Dayak onion contain steroids, tannins, flavonoids and alkaloids. The bioactive compound in ethyl acetate fraction contains steroids, tannins, triterpenes, flavonoids and glycosides. The bioactive compound in n-hexan fraction contains steroids. The bioactive compound in water fraction fraction contains steroids and tannins. The FTIR demonstrated the presence of C-H alkanes, =C-H alkenes (aliphatic), C-O alcohol, ether, esters and carboxy acid in the ethanol extract, en-hexan fractions and ethyl acetate fractions. &lt;strong&gt;Conclusion: &lt;/strong&gt;The phytochemical qualitative profiling showed that Dayak onion bulb as a rich source of bioactive compounds and have medicinal potential as therapeutic agent. A higher content of bioactive compounds of Dayak onion bulbs found in the ethanol and ethyl acetate extracts. The FTIR demonstrated the presence of C-H alkanes, =C-H alkenes (aliphatic), C-O alcohol, ether, esters and carboxy acid in the ethanol extract, enhexan fractions and ethyl acetate fractions.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">88</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Lokot Donna Lubis&lt;sup&gt;1,2&lt;/sup&gt;*, Muhammad Fidel Ganis Siregar&lt;sup&gt;3&lt;/sup&gt;, Farhat4, Iqbal Pahlevi Adeputra Nasution&lt;sup&gt;5&lt;/sup&gt;, Dedy Syahrizal&lt;sup&gt;6&lt;/sup&gt;, Kamal Basri Siregar&lt;sup&gt;7&lt;/sup&gt;, Putri Chairani Eyanoer&lt;sup&gt;8&lt;/sup&gt;, Ichwanul Adenin&lt;sup&gt;3&lt;/sup&gt;, Muhammad Rusda&lt;sup&gt;1,9&lt;/sup&gt; Mustafa M. Amin&lt;sup&gt;1,10&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Philosophy Doctor in Medicine Program, Faculty of Medicine, Universitas Sumatera Utara, Medan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Histology, Faculty of Medicine, Universitas Sumatera Utara, Medan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sumatera Utara, Medan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Ear, Nose, Throat, Head, and Neck, Faculty of Medicine, Universitas Sumatera Utara, Medan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Pediatric Surgery, Faculty of Medicine, Universitas Sumatera Utara, Medan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Biochemistry, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Department of Surgery, Faculty of Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;8&lt;/sup&gt;Department of Community Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;9&lt;/sup&gt;Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sumatera Utara, Medan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;10&lt;/sup&gt;Department of Psychiatry, Faculty of Medicine Universitas Sumatera Utara, Medan, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Viani Anggi</style></author><author><style face="normal" font="default" size="100%">Magfirah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Effect Hypoglycemic of Ethanol Extract Combination Red Betel Leaf (Piper crocatum) and Dayak Onion (Eleutherine palmifolia Merr) in Streptozotocin-Induced</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Dayak onion</style></keyword><keyword><style  face="normal" font="default" size="100%">Hypoglycemic</style></keyword><keyword><style  face="normal" font="default" size="100%">Red betel leaf</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1401-1405</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Red betel leaf and Dayak onion is used traditionally to treat diabetes mellitus, The use of this combination of extracts to assess the effectiveness of the combination therapy is getting better by working synergistically. &lt;strong&gt;Objective: &lt;/strong&gt;This study aimed to determine the hypoglycemic effect and the effective dose of ethanol extract combination of red betel leaf and Dayak onion of male rats (Rattus norvegicus). &lt;strong&gt;Methods: &lt;/strong&gt;The number of 35 male rats were divided into 7 groups and each group consisted of five rats. The first group (normal control) was given Na CMC; the second group (negative control) streptozotocin-induced ; the third group (positive control) glibenclamide , while the 4&lt;sup&gt;th&lt;/sup&gt;, 5&lt;sup&gt;th&lt;/sup&gt;,6&lt;sup&gt;th&lt;/sup&gt;, and 7&lt;sup&gt;th&lt;/sup&gt; were successively given a single dose of ethanol extract of red betel leaf 25 mg/KgBB, a single dose of Dayak onion50 mg/ KgBB, combination red betel leaf and forest onion bulbs, 25+50 and 50+100 mg/kg bb. Each rat group was intraperitoneally (IP) induced with STZ 40 mg/KgBB and then treated for 21 days. The hypoglycemic effect was tested by using the God- Pap method. &lt;strong&gt;Result: &lt;/strong&gt;Phytochemical analysis revealed that flavonoids, tannins, saponins, phytosterols and phenols were present in ethanol extract of red betel leaf and forest onion bulbs. The study concluded that the combination of red betel leaf and Dayak onion at doses 25 mg/KgBB and 50 mg/KgBB were synergistic in reducing glucose. &lt;strong&gt;Conclusion:&lt;/strong&gt; In conclusion, the ethanol extract combination of red betel leaf and dayak onion have hypoglycemic effects.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1401</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Viani Anggi*, Magfirah &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;College of Pharmaceutical Sciences Pelita Mas Palu, Central Sulawesi 94111, INDONESIA.&lt;/p&gt;
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