<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Afriwardi</style></author><author><style face="normal" font="default" size="100%">Adrul Fauzan</style></author><author><style face="normal" font="default" size="100%">Salman Umar</style></author><author><style face="normal" font="default" size="100%">Yufri Aldi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Complete Blood Profile after administration of Hydrocotyle sibthorpioides Lam. extract in capsule form</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Banded neutrophil</style></keyword><keyword><style  face="normal" font="default" size="100%">Basophils</style></keyword><keyword><style  face="normal" font="default" size="100%">Eosinophils</style></keyword><keyword><style  face="normal" font="default" size="100%">erythrocytes</style></keyword><keyword><style  face="normal" font="default" size="100%">Haematology</style></keyword><keyword><style  face="normal" font="default" size="100%">Haemoglobin</style></keyword><keyword><style  face="normal" font="default" size="100%">Hematocrit</style></keyword><keyword><style  face="normal" font="default" size="100%">Hydrocotile sibthorpioides Lam.</style></keyword><keyword><style  face="normal" font="default" size="100%">Immunostimulants</style></keyword><keyword><style  face="normal" font="default" size="100%">Leukocytes</style></keyword><keyword><style  face="normal" font="default" size="100%">Lymphocyte</style></keyword><keyword><style  face="normal" font="default" size="100%">Monocytes</style></keyword><keyword><style  face="normal" font="default" size="100%">Segmented neutrophil</style></keyword><keyword><style  face="normal" font="default" size="100%">Thrombocytes.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">375-383</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Pegagan embun (&lt;em&gt;Hydrocotyle sibthorpioides&lt;/em&gt; Lam.) has been studied as an immunostimulant, increasing macrophage cell activity and phagocytosis capacity. Based on that circumstance, the study aims to prove the immunostimulating effect by measuring the activity of &lt;em&gt;Hydrocotyle sibthorpioides&lt;/em&gt; Lam. extract in the capsule for the complete blood profile of healthy volunteers. The number of volunteers used was twenty people, and the volunteers were divided into two groups. The first group was given a placebo capsule without &lt;em&gt;Hydrocotyle sibthorpioides&lt;/em&gt; Lam. extract. The second group was given a capsule with &lt;em&gt;Hydrocotyle sibthorpioides&lt;/em&gt; Lam. extract with a dose of 67 mg, which was taken once a day for three days. Blood sampling was obtained before and after taking the capsule preparation. Observation of the complete blood profile was conducted by investigating changes in blood parameters such as haemoglobin levels, number of erythrocytes, number of leukocytes, hematocrit values, number of thrombocytes and the percentage of leukocyte types (banded neutrophils, segmented neutrophils, eosinophils, basophils, monocytes, and lymphocytes). The second group given &lt;em&gt;Hydrocotyle sibthorpioides &lt;/em&gt;Lam. extract showed a significant effect on the increase in haemoglobin levels, number of thrombocytes and hematocrit values (p&amp;lt;0.05). The percentage of leukocyte type values showed that lymphocytes increased significantly (p&amp;lt;0.05). In contrast, the segmented neutrophil increased but did not show a significant difference with the percentage of banded neutrophils, eosinophils, basophils and monocytes (p&amp;gt;0.05). There was a nonsignificant result in all parameters for the first group, which was administrated with a placebo capsule without &lt;em&gt;Hydrocotyle sibthorpioides&lt;/em&gt; Lam. extract.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">375</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Afriwardi&lt;sup&gt;1,*&lt;/sup&gt;, Adrul Fauzan&lt;sup&gt;2&lt;/sup&gt;, Salman Umar&lt;sup&gt;2&lt;/sup&gt; , Yufri Aldi&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Medicine, Universitas Andalas, Padang, West Sumatra, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Pharmacy, Universitas Andalas, Padang, West Sumatra, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Salman Umar</style></author><author><style face="normal" font="default" size="100%">Nengsyih Putri Erman</style></author><author><style face="normal" font="default" size="100%">Armenia</style></author><author><style face="normal" font="default" size="100%">Elsa Badriyya</style></author><author><style face="normal" font="default" size="100%">Yufri Aldi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Activities of Pegagan Embun (Hydrocotyle sibthorpioides Lam.) on TNF-α, Macrophages and Leukocytes Male White Mice Exposed by H5N1 Virus Antigens</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Hydrocotyle sibthorpioides Lam.</style></keyword><keyword><style  face="normal" font="default" size="100%">Immunomodulators</style></keyword><keyword><style  face="normal" font="default" size="100%">Leukocytes</style></keyword><keyword><style  face="normal" font="default" size="100%">Leukocytes types</style></keyword><keyword><style  face="normal" font="default" size="100%">Macrophages</style></keyword><keyword><style  face="normal" font="default" size="100%">TNF-α</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">253-261</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Pegagan embun (&lt;em&gt;Hydrocotyle sibthorpioides &lt;/em&gt;Lam.) has been known to have immunostimulatory activity, it can increase the activity and capacity of mice macrophage phagocytosis at optimum dose of 200 mg/kgbw. &lt;strong&gt;Aim:&lt;/strong&gt; This study aims to determine the activity of the ethanol extract of pegagan embun on TNF-α levels, total macrophages, total leukocytes, and percentage of leukocytes types. &lt;strong&gt;Methods:&lt;/strong&gt; Mice were divided into four groups, one group as control was given 0.5% Na CMC suspension, three groups were given pegagan embun extract at a dose of 10 mg/kgbw, 50 mg/kgbw and 200 mg/kgbw orally for 7 days. On the 8&lt;sup&gt;th&lt;/sup&gt; day, all mice were induced with 0.3 mL H5N1 vaccine subcutaneously, then left for 24 hours. After 24 hours, the mice were sacrificed and then TNF-α levels, total macrophages, total leukocytes, and percentage of leukocytes types were determined. The research data were analyzed using one-way ANOVA (significance was taken at p&amp;lt;0.05) and continued with the Duncan test.&lt;strong&gt; Results: &lt;/strong&gt;The results showed that pegagan embun extract significantly reduce TNF-α levels and total macrophages, also significantly increase total leukocytes and percentage of leukocyte types in mice (p&amp;lt;0.05). Significant increases and decreases occurred on average at doses of 50 mg/kgbw and 200 mg/kgbw. &lt;strong&gt;Conclusion:&lt;/strong&gt; Based on these results, it can be concluded that pegagan embun extract have immunomodulatory activity.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><accession-num><style face="normal" font="default" size="100%">01</style></accession-num><section><style face="normal" font="default" size="100%">253</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Salman Umar*, Nengsyih Putri Erman, Armenia, Elsa Badriyya, Yufri Aldi&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Faculty of Pharmacy, University Andalas, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Afriwardi</style></author><author><style face="normal" font="default" size="100%">Rahmatul Nazmi</style></author><author><style face="normal" font="default" size="100%">Dwisari Dillasamola</style></author><author><style face="normal" font="default" size="100%">Elsa Badriyya</style></author><author><style face="normal" font="default" size="100%">Yufri Aldi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anti-inflammatory Activity of Pegagan Embun (Hydrocotyle sibthorpioides Lam.) Plant Extract on Topical Application</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-inflammatory</style></keyword><keyword><style  face="normal" font="default" size="100%">Exudate</style></keyword><keyword><style  face="normal" font="default" size="100%">Gel</style></keyword><keyword><style  face="normal" font="default" size="100%">Hydrocotyle sibthorpioides Lam.</style></keyword><keyword><style  face="normal" font="default" size="100%">Ketoprofen</style></keyword><keyword><style  face="normal" font="default" size="100%">Leukocytes</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">411-417</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Pegagan embun (&lt;em&gt;Hydrocotyle sibthorpioides&lt;/em&gt; Lam.) is traditionally known to have many benefits, including anti-inflammatory.&lt;strong&gt; Aims:&lt;/strong&gt; This study aimed to determine the activity of ethanol extract of Pegagan Embun as an anti-inflammatory using the granuloma pouch method. &lt;strong&gt;Methods:&lt;/strong&gt; This experiment used 25 male white mice and were divided into five groups, namely, the positive control group, &lt;em&gt;Hydrocotyle sibthorpioides &lt;/em&gt;Lam. extract group with concentration 0.5%; 1%; 2%, and the comparison group that given Kaltrofen® gel containing 2.5% ketoprofen. Experimental animals were given carrageenan 2% to induced the inflammation subcutaneously. The dosage form was given as much as 0.2 g topically for four days once a day. &lt;strong&gt;Results:&lt;/strong&gt; Based on the results of one-way ANOVA analysis and Duncan's test, there were significant differences in exudate volume and total leukocytes (p&amp;lt;0.05) in the positive control group, extract with concentration 0.5%, 1%, 2%, and the comparator. While the percentage of leukocyte cells showed that they were not significantly different (p&amp;gt;0.05), the number of neutrophil cells decreased. &lt;strong&gt;Conclusion:&lt;/strong&gt; From the overall data obtained, it can be concluded that the extract of &lt;em&gt;Hydrocotyle sibthorpioides&lt;/em&gt; Lam. at concentration 0.5 %; 1%; 2%, has an anti-inflammatory effect.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">411</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Afriwardi&lt;sup&gt;1,&lt;/sup&gt;*, Rahmatul Nazmi&lt;sup&gt;2&lt;/sup&gt;, Dwisari Dillasamola&lt;sup&gt;2&lt;/sup&gt;, Elsa Badriyya&lt;sup&gt;2&lt;/sup&gt;, Yufri Aldi&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Medicine, Andalas University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Pharmacy, Andalas University, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hugo Jesús Justil-Guerrero</style></author><author><style face="normal" font="default" size="100%">Jorge Luis Arroyo-Acevedo</style></author><author><style face="normal" font="default" size="100%">Juan Pedro Rojas-Armas</style></author><author><style face="normal" font="default" size="100%">Miriam Palomino- Pacheco</style></author><author><style face="normal" font="default" size="100%">Magaly Villena-Tejada</style></author><author><style face="normal" font="default" size="100%">Wilmer Atilio Segura Vílchez</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant Capacity of Chuquiraga Spinosa Less. &quot;Huamanpinta&quot; and Prevention of Carrageenan-Induced Inflammation in Mice</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Ethanolic extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Leukocytes</style></keyword><keyword><style  face="normal" font="default" size="100%">Lipoperoxidation</style></keyword><keyword><style  face="normal" font="default" size="100%">Nitric oxide</style></keyword><keyword><style  face="normal" font="default" size="100%">Oxidative stress</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1287-1296</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; To evaluate the antioxidant capacity of &lt;em&gt;Chuquiraga spinosa &lt;/em&gt;extracts and prevention of carrageenan-induced inflammation in mice. &lt;strong&gt;Methodology:&lt;/strong&gt; Experimental design: plant species, erythrocytes and male BALB C53 mice, were considered as biological material. Antioxidant capacity was evaluated in 50%, 70%, 96% and aqueous ethanolic extracts by 2,2-Diphenyl-1-Picrylhydrazyl reduction, malondialdehyde inhibition in oxidized erythrocytes with H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt; and correlating with polyphenol content equivalent to gallic acid/gram dry extract. Inflammation was evaluated by inoculating carrageenan 2% in &quot;subcutaneous air bag&quot; of mice: 1) White, 2) carrageenan, 3) dexamethasone 2 mg/kg, 4-6) ethanolic extract 70% doses 100, 250 and 500 mg/kg respectively; determining nitric oxide, malondialdehyde, total proteins, albumin, leukocytes in exudate and histological changes. &lt;strong&gt;Results: &lt;/strong&gt;Alkaloids, flavonoids, terpenes, phenolic compounds, tannins, carbohydrates, triterpenes, steroids and sesquiterpene lactones were identified; aqueous extract presented greater reduction of 2,2-Diphenyl-1-Picrylhydrazyl (CI50 = 58.99 μg/mL), ethanolic extract 70% presented greater inhibition of malondialdehyde in erythrocytes (CI50 = 16.44 nm/mL); It was observed that the higher the amount of polyphenols, the greater the reduction of 2,2-Diphenyl-1-Picrylhydrazyl (r=-0.909) and the greater the inhibition of malondialdehyde (r=-0.781). With 500 mg/kg of 70% ethanolic extract there was greater anti-inflammatory effect inhibiting malondialdehyde, nitric oxide, albumin, total proteins and leukocytes in 55.55%, 81.92%, 41.20%, 31.51% and 32.45% (p&amp;lt;0.01) respectively and less infiltration of leukocytes and lymphocytes in air sac membrane. &lt;strong&gt;Conclusion: &lt;/strong&gt;The extracts of aerial parts of &lt;em&gt;Chuquiraga spinosa&lt;/em&gt; showed antioxidant capacity correlated to polyphenol content. The 70% ethanolic extract prevented inflammation in mice in a dosedependent manner.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1287</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Hugo Jesús Justil-Guerrero&lt;sup&gt;1,2&lt;/sup&gt;, Jorge Luis Arroyo-Acevedo&lt;sup&gt;1,2&lt;/sup&gt;, Juan Pedro Rojas-Armas&lt;sup&gt;1,2,&lt;/sup&gt; Miriam Palomino-Pacheco&lt;sup&gt;1&lt;/sup&gt;, Magaly Villena-Tejada&lt;sup&gt;3,&lt;/sup&gt;*, Wilmer Atilio Segura Vílchez&lt;sup&gt;4&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Pharmacology Laboratory of the Faculty of Medicine of the Universidad Nacional Mayor de San Marcos. Lima, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Clinical Research Institute of the Faculty of Medicine of the Universidad Nacional Mayor de San Marcos. Lima, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Academic Department of Pharmacy, Faculty of Health Sciences, Universidad Nacional de San Antonio Abad del Cusco. Cusco, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Management of Forensic Thanatology of the Institute of Legal Medicine and. Forensic Sciences. Public Prosecutor's Office. Lima, PERÚ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Afriwardi</style></author><author><style face="normal" font="default" size="100%">Yufri Aldi</style></author><author><style face="normal" font="default" size="100%">Dwisari Dillasamola</style></author><author><style face="normal" font="default" size="100%">Yolanda Alfiyyah Larakhansa</style></author><author><style face="normal" font="default" size="100%">Elsa Badriyya</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Immunostimulatory Activities of Pegagan Embun (Hydrocotyle sibthorpioides Lam.) in White Male Mice</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Hydrocotyle sibthorpioides Lam.</style></keyword><keyword><style  face="normal" font="default" size="100%">Leukocytes</style></keyword><keyword><style  face="normal" font="default" size="100%">Macrophage</style></keyword><keyword><style  face="normal" font="default" size="100%">Phagocytosis</style></keyword><keyword><style  face="normal" font="default" size="100%">Staphylococcus aureus</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">368-375</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt;&lt;em&gt; Pegagan embun&lt;/em&gt; (&lt;em&gt;Hydrocotyle sibthorpioides&lt;/em&gt; L.) has many pharmacological activies, such as improving the immune system. &lt;strong&gt;Aim: &lt;/strong&gt;This research aims to study the immunomodulatory effect of &lt;em&gt;Pegagan embun&lt;/em&gt; herbs ethanol extract (&lt;em&gt;Hydrocotyle sibthorpioides &lt;/em&gt;L.) determined by phagocytic activity and capacity of macrophages, total and percentage of leukocytes. &lt;strong&gt;Methods: &lt;/strong&gt;25 male white mice were divided into 5 equal groups. Negative control group were given Na CMC 0.5%, the extract treated group were given &lt;em&gt;Pegagan embun&lt;/em&gt; ethanol extract at doses of 10, 50, 200 mg/kgbw, and the positive control group was given Stimuno 50 mg/kgbw orally for 7 days. On the 8&lt;sup&gt;th&lt;/sup&gt; day, the total and percentage of leukocytes were counted through blood sample taken intravenously. The mice were then induced with &lt;em&gt;Staphylococcus aureus &lt;/em&gt;suspension. After one hour, the peritoneal fluids was taken to determine the macrophages activity and capacity. The macrophages phagocytic activity and capacity, total and percentage of leukocytes were analyzed by One-Way Anova followed by Duncan Multiple Range Test (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05). &lt;strong&gt;Results:&lt;/strong&gt; The results show significant increase of concentration (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05) towards macrophages phagocytic activity and capacity, and total leukocytes count. Percentage of leukocytes show that lymphocytes increase significantly (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05), meanwhile neutrophils segments decrease significantly (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05). &lt;strong&gt;Conclusion: &lt;/strong&gt;It can be concluded that ethanol extract of &lt;em&gt;Pegagan embun&lt;/em&gt; herb at doses of 10, 50, 200 mg/kgbw shows immunostimulatory activity.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">368</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Afriwardi&lt;sup&gt;1,&lt;/sup&gt;*, Yufri Aldi&lt;sup&gt;2&lt;/sup&gt;, Dwisari Dillasamola&lt;sup&gt;2&lt;/sup&gt;, Yolanda Alfiyyah Larakhansa&lt;sup&gt;2&lt;/sup&gt;, Elsa Badriyya&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Medicine, Andalas University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Pharmacy, Andalas University, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dwisari Dillasamola</style></author><author><style face="normal" font="default" size="100%">Yufri Aldi</style></author><author><style face="normal" font="default" size="100%">Marselani Kolobinti</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Effect of Coriander Ethanol Extract (Coriandrum sativum L.) Against Phagocytosis Activity and Capacity of the Macrophage Cells and the Percentage of Leukocyte Cells in White Male Mice</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Coriandrum sativum</style></keyword><keyword><style  face="normal" font="default" size="100%">Leukocytes</style></keyword><keyword><style  face="normal" font="default" size="100%">Macrophages</style></keyword><keyword><style  face="normal" font="default" size="100%">Phagocytosis capacity</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1290-1298</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Coriander has long been used by humans as a traditional drug and to enhances the taste of foods. This study aims to know the effects of coriander ethanol extract against phagocytosis activity and capacity of the macrophage cells and the percentage of leukocytes. The test animals used were white male mice which divided into 4 groups and each group consists of 5 mice. The first group (control) was given with 0.5% Na CMC suspension. The second, the third, and the fourth groups were given with coriander extract each with doses of 100 mg/kg, 140 mg/kg and 200 mg/kg orally for 7 days long. On the 8th day, the mice were induced by &lt;em&gt;Staphylococcus aureus &lt;/em&gt;to help their immune system. The results showed that the administration of coriander extract at doses of 100, 140 and 200 mg/kg can increase the phagocytic activity of macrophages by 44.6%; 54.2%; and 60.2% each, while the phagocytic capacity replaces the results of 95.8; 104.4; and 126 cells. The total number of leukocytes showed were 5210, 6190, and 7310 /μL blood. In the number of leukocyte cells, the amount of coriander extract can reduce the number of neutrophil and monocyte cell segments. The conclusion of this study regarding coriander ethanol extract at doses of 100, 140 and 200 mg/kg can increase phagocytosis activity and capacity of the macrophage cells and the total leukocyte cell counts in male white mice.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1290</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Dwisari Dillasamola*, Yufri Aldi, Marselani Kolobinti&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Faculty of Pharmacy, Department of Pharmacology, Andalas University, Padang, INDONESIA.&lt;/p&gt;
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