<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mohamed Zaeim Hafez Ahmed</style></author><author><style face="normal" font="default" size="100%">Muhammad Abdelbaeth Hassan Elfiky</style></author><author><style face="normal" font="default" size="100%">Elsayed Elagamy Elsayed Mohamed</style></author><author><style face="normal" font="default" size="100%">Ramadan Hassan Ibrahim Thabet</style></author><author><style face="normal" font="default" size="100%">Ahmed Mohamed Gad Allah</style></author><author><style face="normal" font="default" size="100%">Ahmed Abdrabo Elshenawy Elsisi</style></author><author><style face="normal" font="default" size="100%">Ahmed Abdel Nasser Ahmed Mohamed</style></author><author><style face="normal" font="default" size="100%">Tarek Shikhon</style></author><author><style face="normal" font="default" size="100%">Mostafa Abo-akrab</style></author><author><style face="normal" font="default" size="100%">Sayed A.M.Mahmoud</style></author><author><style face="normal" font="default" size="100%">Mohamed AbdelAziz Doma</style></author><author><style face="normal" font="default" size="100%">Wael Ahmed Mahmoud Khattab</style></author><author><style face="normal" font="default" size="100%">Khaled Saleh Ali Elhamaky</style></author><author><style face="normal" font="default" size="100%">Mohamed El- Salamoni</style></author><author><style face="normal" font="default" size="100%">Fatma Mahmoud Abdelraheem</style></author><author><style face="normal" font="default" size="100%">Mahmoud Ahmad Mohamed Azab</style></author><author><style face="normal" font="default" size="100%">Mahmoud Ahmad Mohamed Azab6</style></author><author><style face="normal" font="default" size="100%">Mohamed E EL-Refaey</style></author><author><style face="normal" font="default" size="100%">Ahmed A. Abd El-Rhman</style></author><author><style face="normal" font="default" size="100%">Ahmed F. Abdel Ghany</style></author><author><style face="normal" font="default" size="100%">Ghada Adel Hegazy</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Influence of Chamomile Leaves extract in Different Doses on Renal Functions and Diabetic indices in Streptozotocin – Induced Diabetic Rat</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Chamomile leaves</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetes mellitus</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">1029-1035</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; The prevalence of diabetes among Egyptians is rising. Therefore, there is always a demand for innovative natural medicines. Medicinal plants have long been a significant source in search of novel, effective alternatives for human therapy. Chamomile is one of the most widely used medicinal plants, which may help hyperglycemic patients by lowering blood sugar levels. Objectives: To determine how chamomile extract affects the kidneys when albino male rats with chronic diabetes are induced by streptozotocin (STZ). &lt;strong&gt;Methods:&lt;/strong&gt; The study was conducted in the Al-Azhar Faculty of Medicine (Assiut) pharmacology department animal laboratory. For this investigation, a local strain of fifty adult male albino rats was used as the animal model and weighed 120 to 150 g. In this study, rats were divided into five groups, body weight, and systolic blood pressure was measured, and blood samples were collected for measuring blood glucose and insulin level, HbA1c, Na, K, and renal function tests, and histopathological examination was done. &lt;strong&gt;Results:&lt;/strong&gt; After the study, mean glucose levels, HbA1c, urea, creatinine, K, and systolic blood pressure were significantly decreased in group IV &amp;amp; group V compared to group III. In contrast, body weight serum insulin level and Na increased dramatically in group IV &amp;amp; group V compared to group III.&lt;strong&gt; Conclusion:&lt;/strong&gt; The serum levels of urea and creatinine in diabetic patients may be positively affected by chamomile. Additionally, short-term chamomile uses benefits diabetic individuals by decreasing loss of body weight, lowering HbA1c, and increasing insulin levels.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1029</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Mohamed Zaeim Hafez Ahmed&lt;sup&gt;1*&lt;/sup&gt;, Muhammad Abdelbaeth Hassan Elfiky&lt;sup&gt;1&lt;/sup&gt;, Elsayed Elagamy Elsayed Mohamed&lt;sup&gt;2&lt;/sup&gt;, Ramadan Hassan Ibrahim Thabet&lt;sup&gt;2&lt;/sup&gt;, Ahmed Mohamed Gad Allah&lt;sup&gt;3&lt;/sup&gt;, Ahmed Abdrabo Elshenawy Elsisi&lt;sup&gt;2&lt;/sup&gt;, Ahmed Abdel Nasser Ahmed Mohamed&lt;sup&gt;2&lt;/sup&gt;, Tarek Shikhon&lt;sup&gt;4&lt;/sup&gt;, Mostafa Abo-akrab4, Sayed A.M.Mahmoud&lt;sup&gt;5&lt;/sup&gt;, Mohamed AbdelAziz Doma&lt;sup&gt;5&lt;/sup&gt;, Wael Ahmed Mahmoud Khattab&lt;sup&gt;6&lt;/sup&gt;, Khaled Saleh Ali Elhamaky&lt;sup&gt;7&lt;/sup&gt;, Mohamed El-Salamoni&lt;sup&gt;6&lt;/sup&gt;, Fatma Mahmoud Abdelraheem&lt;sup&gt;8,&lt;/sup&gt; Mahmoud Ahmad Mohamed Azab&lt;sup&gt;6&lt;/sup&gt;, Ashraf Abdel Aty Elshenawy Emara&lt;sup&gt;6&lt;/sup&gt;, Mohamed E EL-Refaey&lt;sup&gt;1&lt;/sup&gt;, Ahmed A. Abd El-Rhman&lt;sup&gt;1&lt;/sup&gt;, Ahmed F. Abdel Ghany&lt;sup&gt;1&lt;/sup&gt;, Ghada Adel&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Faculty of Medicine, Al-Azhar University (Assiut), Assiut, EGYPT.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hamida Sadat</style></author><author><style face="normal" font="default" size="100%">Kawsar Alami</style></author><author><style face="normal" font="default" size="100%">Sayed Yousof Mousavi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of Afghan Senjed (Elaeagnus Angustifolia L.) Leaves Aqueous alcoholic Extract on Blood Glucose Level of Diabetic Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Blood glucose level</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetic rats</style></keyword><keyword><style  face="normal" font="default" size="100%">Elaeagnus Angustifolia leaves</style></keyword><keyword><style  face="normal" font="default" size="100%">Glucose tolerance</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1218-1222</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Diabetes mellitus is a metabolic disorder, which affects many people throughout the world. The inefficacy and multiple side effects of most synthetic anti-diabetic drugs are reported by various studies. Thus, many researchers are focused on the use of medicinal plants as safe and potent anti-hyperglycemic drugs. The aim of this study is the evaluation of the effect of Afghan senjed (&lt;em&gt;Elaeagnus Angustifolia&lt;/em&gt; L.) leaves aqueous alcoholic extract on blood glucose level of diabetic rats. &lt;strong&gt;Methods: &lt;/strong&gt;Rats were divided into 6 groups: normal, diabetic, metformin and &lt;em&gt;Elaeagnus Angustifolia&lt;/em&gt; leaves extract (EALE) groups, which received 200, 400 and 800 mg/kg doses of extract for 15 days. Diabetes was induced by single dose intraperitoneal administration of streptozotocin (STZ). During treatment, the effect of single and repeated oral administration of EALE on blood glucose level of diabetic rats was evaluated. On last day, the effect of EALE on oral glucose tolerance test (OGTT) was also assessed. &lt;strong&gt;Results: &lt;/strong&gt;All doses of EALE showed significant reduction in blood glucose level, an improvement of glucose tolerance and enhancement in body weight. &lt;strong&gt;Conclusion:&lt;/strong&gt; EALE possessed an antihyperglycemic property in diabetic rats.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1218</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Hamida Sadat&lt;sup&gt;1&lt;/sup&gt;, Kawsar Alami&lt;sup&gt;1&lt;/sup&gt;, Sayed Yousof Mousavi&lt;sup&gt;2,&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Research and technology center, Khatam Al- Nabieen University, Karte 4, 1&lt;sup&gt;st&lt;/sup&gt; street, Kabul, AFGHANISTAN.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of physiology, Khatam Al- Nabieen university, Karte 4, 1&lt;sup&gt;st &lt;/sup&gt;street, Kabul, AFGHANISTAN.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sachin Chaudhary</style></author><author><style face="normal" font="default" size="100%">Harish Chandra Verma</style></author><author><style face="normal" font="default" size="100%">Mandeep Kumar Gupta</style></author><author><style face="normal" font="default" size="100%">Hitesh Kumar</style></author><author><style face="normal" font="default" size="100%">Sudhansu Ranjan Swain</style></author><author><style face="normal" font="default" size="100%">Ramesh Kumar Gupta</style></author><author><style face="normal" font="default" size="100%">Abdel-Nasser El-Shorbagi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antidiabetic Aptitude of Cordia sebestena and its Outcome on Biochemical Parameters, Serum Electrolytes, and Hematological Markers</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anemia</style></keyword><keyword><style  face="normal" font="default" size="100%">Antidiabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Cordia sebestena</style></keyword><keyword><style  face="normal" font="default" size="100%">Glucose</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">418-423</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The present study investigated the antidiabetic outcome of ethanolic extract of &lt;em&gt;Cordia sebestena&lt;/em&gt; fruit (EECSF) in streptozotocin (STZ)-induced diabetogenic rodents and evaluated its consequence to improve the level of biochemical parameters, serum electrolytes level, and hematological indices along with its impact on body weight. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; The albino rodents were selected to observe oral glucose tolerance test by oral intake of aqueous glucose solution (4 g/kg, body weight) in normal rodents and assessment of blood glucose level after administration of EECSF at 100 and 200 mg/kg and standard drug glibenclamide at 0.6 mg/kg, body weight. Antidiabetic activity was estimated in the chronic biological model by STZ (65 mg/kg/i.p.)-induced diabetes in rodents escorted by the determination of blood glucose. Further pharmacological research was carried out to explore the effect of EECSF on body weight, variations in biochemical parameters including aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, total bilirubin, and total protein, transformations in serum electrolytes such as Na&lt;sup&gt;+&lt;/sup&gt;, K&lt;sup&gt;+&lt;/sup&gt;, Cl&lt;sup&gt;−&lt;/sup&gt;, and Ca&lt;sup&gt;2+&lt;/sup&gt; along with estimation of hematological indices such as red blood cells, white blood cells, hemoglobin, lymphocytes, neutrophils, eosinophils, and monocytes. &lt;strong&gt;Results:&lt;/strong&gt; It was discovered that EECSF significantly lowered the blood glucose level of diabetic rodents along with enhancement in body weight. Correspondingly, EECSF significantly ameliorated the biochemical parameters, serum electrolytes, and hematological indices. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results demonstrated the antidiabetic potential of EECSF in STZ-induced diabetes in rodents, and it could be selected to benefit from diabetes and its affiliated complexities inclusive of anemia, diabetic nephropathy, retinopathy, neuropathy, and hepatitis.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">418</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Sachin Chaudhary&lt;sup&gt;1&lt;/sup&gt;, Harish Chandra Verma&lt;sup&gt;2&lt;/sup&gt;, Mandeep Kumar Gupta&lt;sup&gt;2&lt;/sup&gt;, Hitesh Kumar&lt;sup&gt;2&lt;/sup&gt;, Sudhansu Ranjan Swain&lt;sup&gt;2&lt;/sup&gt;, Ramesh Kumar Gupta&lt;sup&gt;2&lt;/sup&gt;, Abdel-Nasser El-Shorbagi&lt;sup&gt;1,3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, UNITED ARAB EMIRATES.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmaceutical Chemistry and Pharmaceutics, Moradabad Educational Trust, Group of Institutions, Faculty of Pharmacy, Uttar Pradesh, INDIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Sharjah Institute for Medical Research, University of Sharjah, Sharjah, UNITED ARAB EMIRATES.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Balasubramanian Prasanna</style></author><author><style face="normal" font="default" size="100%">Arumugam Vijaya Anand</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Cinnamon species: In vivo Anti-Oxidant Activity of Ethanolic Extracts of Cinnamon Zeylanicum and Cinnamon Cassicae Barks</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-oxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Cinnamon cassicae</style></keyword><keyword><style  face="normal" font="default" size="100%">Cinnamon zeylanicum</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetes mellitus</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">245-247</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Background:&lt;/strong&gt; The diabetic population is increasing highly in the worldwide due to the poor control of diabetes and environmental conditions. It disturbs the carbohydrate, protein and lipid metabolism. The natural medicines obtained from the plant source may be the effective treatment of diabetes. &lt;strong&gt;Objective:&lt;/strong&gt; The aim of the present study is to investigate the antioxidant activities of the ethanolic bark extract of &lt;em&gt;Cinnamon zeylanicum&lt;/em&gt; and&lt;em&gt; Cinnamon cassiacae&lt;/em&gt;. in streptozotocin (STZ) induced oxidative stress in rats. &lt;strong&gt;Methods:&lt;/strong&gt; Oxidative stress is induced with a single dose of STZ 60 mg/kg b.w. and then the animals are treated with a dose of various concentrations of ethanolic bark extract of &lt;em&gt;Cinnamon zeylanicum&lt;/em&gt; and&lt;em&gt; Cinnamon cassiacae&lt;/em&gt; (200 mg/kg b.w, 400 mg/kg b.w, and 600 mg/ kg b.w) for 45 days. After the treatment lipid peroxides (LPO), reduce glutathione (GSH), glutathione peroxidase (GPx), superoxide dismutase (SOD) and catalase (CAT) levels are determined. Glibenclamide is used as a standard drug (3 mg/kg b.w.). &lt;strong&gt;Results:&lt;/strong&gt; The present study exposed that the administration of ethanolic bark extract of&lt;em&gt; Cinnamon zeylanicum &lt;/em&gt;and &lt;em&gt;Cinnamon cassiacae&lt;/em&gt; showed a significant decrease in LPO levels. The treatment also finds that the significant increase in GSH, GPx, SOD and CAT levels in the liver, when compared with diabetic control rats. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results proved that the ethanolic bark extract of &lt;em&gt;Cinnamon zeylanicum&lt;/em&gt; and&lt;em&gt; Cinnamon cassiacae&lt;/em&gt; treated group may effectively regulate the antioxidant status in STZ induced diabetic treated groups.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">245</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Balasubramanian Prasanna&lt;sup&gt;1,&lt;/sup&gt;*, Arumugam Vijaya Anand&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of BioChemistry, Manonmaniam Sundaranar University, Tirunelveli, Tamil Nadu, INDIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore-641 046, Tamil Nadu, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Viani Anggi</style></author><author><style face="normal" font="default" size="100%">Magfirah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Effect Hypoglycemic of Ethanol Extract Combination Red Betel Leaf (Piper crocatum) and Dayak Onion (Eleutherine palmifolia Merr) in Streptozotocin-Induced</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Dayak onion</style></keyword><keyword><style  face="normal" font="default" size="100%">Hypoglycemic</style></keyword><keyword><style  face="normal" font="default" size="100%">Red betel leaf</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1401-1405</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Red betel leaf and Dayak onion is used traditionally to treat diabetes mellitus, The use of this combination of extracts to assess the effectiveness of the combination therapy is getting better by working synergistically. &lt;strong&gt;Objective: &lt;/strong&gt;This study aimed to determine the hypoglycemic effect and the effective dose of ethanol extract combination of red betel leaf and Dayak onion of male rats (Rattus norvegicus). &lt;strong&gt;Methods: &lt;/strong&gt;The number of 35 male rats were divided into 7 groups and each group consisted of five rats. The first group (normal control) was given Na CMC; the second group (negative control) streptozotocin-induced ; the third group (positive control) glibenclamide , while the 4&lt;sup&gt;th&lt;/sup&gt;, 5&lt;sup&gt;th&lt;/sup&gt;,6&lt;sup&gt;th&lt;/sup&gt;, and 7&lt;sup&gt;th&lt;/sup&gt; were successively given a single dose of ethanol extract of red betel leaf 25 mg/KgBB, a single dose of Dayak onion50 mg/ KgBB, combination red betel leaf and forest onion bulbs, 25+50 and 50+100 mg/kg bb. Each rat group was intraperitoneally (IP) induced with STZ 40 mg/KgBB and then treated for 21 days. The hypoglycemic effect was tested by using the God- Pap method. &lt;strong&gt;Result: &lt;/strong&gt;Phytochemical analysis revealed that flavonoids, tannins, saponins, phytosterols and phenols were present in ethanol extract of red betel leaf and forest onion bulbs. The study concluded that the combination of red betel leaf and Dayak onion at doses 25 mg/KgBB and 50 mg/KgBB were synergistic in reducing glucose. &lt;strong&gt;Conclusion:&lt;/strong&gt; In conclusion, the ethanol extract combination of red betel leaf and dayak onion have hypoglycemic effects.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1401</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Viani Anggi*, Magfirah &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;College of Pharmaceutical Sciences Pelita Mas Palu, Central Sulawesi 94111, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Towseef Hassan</style></author><author><style face="normal" font="default" size="100%">Elanchezhiyan C</style></author><author><style face="normal" font="default" size="100%">Insha Naseer</style></author><author><style face="normal" font="default" size="100%">S Marimuthu</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of Perillyl Alcohol (POH) A Monoterpene on Lipid Peroxidation and Antioxidant Status in High Fat Diet-Low Dose STZ Induced Type 2 Diabetes in Experimental Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidants</style></keyword><keyword><style  face="normal" font="default" size="100%">High Fat Diet</style></keyword><keyword><style  face="normal" font="default" size="100%">Lipid peroxidation</style></keyword><keyword><style  face="normal" font="default" size="100%">Perillyl alcohol</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1434-1441</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Aim:&lt;/strong&gt; The plan of this study was to assess the protective activity of Perillyl alcohol (POH) on the levels of lipid peroxidation (LPO) by-products and antioxidant defense systems in the plasma and other tissues of normal and High Fat Diet-Low Dose Streptozotocin (STZ) induced type 2 diabetes in wistar rats. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; The experimental diabetes was induced in animals by High Fat Diet-Low Dose STZ (35 mg/kg i.p.) injection, and treatment with Perillyl alcohol at the dose of (50mg/kg b.w and 100mg/kg b.w) was continued for 30 days. At the end of treatment period, oxidative stress parameters like lipid peroxidation by-products; enzymatic antioxidants such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and non-enzymic antioxidants including reduced glutathione, Vitamin C and Vitamin E were measured in the plasma and tissues of experimental rats. &lt;strong&gt;Results:&lt;/strong&gt; In untreated diabetic rats an increase was seen in the levels of lipid peroxidation by-products and significant decrease was seen in antioxidant enzymes. Oral administration of Perillyl alcohol a monocyclic monoterpene to diabetic rats for 30 days caused a significant reduction in the levels of lipid peroxidation by-products and an increase in the activities of antioxidant enzymes, when the same were compared with the untreated diabetic group. &lt;strong&gt;Conclusion:&lt;/strong&gt; The result of this study indicates that Perillyl alcohol has anti lipid peroxidation and antioxidant status potential in experimental diabetes.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1434</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Towseef Hassan, Elanchezhiyan C*, Insha Naseer, S. Marimuthu&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Zoology, Annamalai University, Annamalainagar, Chidambaram-608002, Tamil Nadu, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of Porana paniculata Whole Plant on Blood Glucose Levels and Lipid Profile of STZ Induced Diabetic Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Diabetes</style></keyword><keyword><style  face="normal" font="default" size="100%">Folklore</style></keyword><keyword><style  face="normal" font="default" size="100%">lipid profile</style></keyword><keyword><style  face="normal" font="default" size="100%">Porana paniculata</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2019</style></date></pub-dates></dates><pages><style face="normal" font="default" size="100%">xx-xx</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;strong&gt;Background&lt;/strong&gt;: To establish the antidiabetic potential of Porana paniculata whole plant belongs to &lt;em&gt;Convolvulaceae&lt;/em&gt; family. &lt;strong&gt;Methods&lt;/strong&gt;: Extraction and preliminary phytochemical screening were conducted by standard methods. Antidiabetic activity was evaluated by streptozotocin induced diabetic rats where the hydroalcoholic extract of plant was administered orally at a dose of 250 and 500 mg/kg for 30 days. Blood glucose levels were estimated at 1&lt;sup&gt;st&lt;/sup&gt;, 10&lt;sup&gt;th&lt;/sup&gt;, 20&lt;sup&gt;th&lt;/sup&gt; and 30&lt;sup&gt;th&lt;/sup&gt; day of study. Lipid profile was studied 30&lt;sup&gt;th&lt;/sup&gt; day of study and body weight of the animals was measured at day 1 and 30.&lt;strong&gt; Results&lt;/strong&gt;: Plant extract significantly (&lt;em&gt;p&amp;lt;&lt;/em&gt;0.01) reduced the blood glucose levels at both the tested dose levels of 250 and 500 mg/kg. The lipid profile was estimated in which the plant extract showed significant improved in both tested dose level that is 250 and 500 mg/kg. The body weight of the animals under study was also estimated on day 1 and 30 in which a good control was observed by the plant extract. &lt;strong&gt;Conclusion&lt;/strong&gt;: Antidiabetic activity of Porana paniculata whole plant extract may be due to the presence of various phytoconstituents. Present study gives a scientific evidence for the folklore claim of the plant under study for its use in diabetes.&lt;/p&gt;
</style></abstract><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">xx</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Sanjeeva Kumar A&lt;sup&gt;1,&lt;/sup&gt;*, Raveendra Reddy Juturu&lt;sup&gt;1&lt;/sup&gt;, Rama Mohan Gupta Vankadari&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Division of Pharmacognosy, Raghavendra Institute of Pharmaceutical Education and Research, Krishnam Reddy Palli cross, Chiyyedu, Anantapuramu-515721, Andhra Pradesh, INDIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Pulla Reddy Institute of Pharmacy, Near Dundigal Air force Academy, Annaram Village, Jinnaram Mandal, Medak- 502313, Andhra Pradesh, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sanjeeva Kumar A</style></author><author><style face="normal" font="default" size="100%">Raveendra Reddy Juturu</style></author><author><style face="normal" font="default" size="100%">Rama Mohan Gupta Vankadari</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of Porana paniculata Whole Plant on Blood Glucose Levels and Lipid Profile of STZ Induced Diabetic Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Diabetes</style></keyword><keyword><style  face="normal" font="default" size="100%">Folklore</style></keyword><keyword><style  face="normal" font="default" size="100%">lipid profile</style></keyword><keyword><style  face="normal" font="default" size="100%">Porana paniculata</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2019</style></date></pub-dates></dates><pages><style face="normal" font="default" size="100%">xx-xx</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; To establish the antidiabetic potential of &lt;em&gt;Porana paniculata&lt;/em&gt; whole plant belongs to Convolvulaceae family. &lt;strong&gt;Methods:&lt;/strong&gt; Extraction and preliminary phytochemical screening were conducted by standard methods. Antidiabetic activity was evaluated by streptozotocin induced diabetic rats where the hydroalcoholic extract of plant was administered orally at a dose of 250 and 500 mg/kg for 30 days. Blood glucose levels were estimated at 1&lt;sup&gt;st&lt;/sup&gt;, 10&lt;sup&gt;th&lt;/sup&gt;, 20&lt;sup&gt;th&lt;/sup&gt; and 30&lt;sup&gt;th&lt;/sup&gt; day of study. Lipid profile was studied 30&lt;sup&gt;&lt;s&gt;th&lt;/s&gt;&lt;/sup&gt; day of study and body weight of the animals was measured at day 1 and 30.&lt;strong&gt; Results:&lt;/strong&gt; Plant extract significantly (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.01) reduced the blood glucose levels at both the tested dose levels of 250 and 500 mg/kg. The lipid profile was estimated in which the plant extract showed significant improved in both tested dose level that is 250 and 500 mg/kg. The body weight of the animals under study was also estimated on day 1 and 30 in which a good control was observed by the plant extract. &lt;strong&gt;Conclusion:&lt;/strong&gt; Antidiabetic activity of &lt;em&gt;Porana paniculata&lt;/em&gt; whole plant extract may be due to the presence of various phytoconstituents. Present study gives a scientific evidence for the folklore claim of the plant under study for its use in diabetes.&lt;/p&gt;
</style></abstract><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">xx</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Sanjeeva Kumar A&lt;sup&gt;1*&lt;/sup&gt;, Raveendra Reddy Juturu&lt;sup&gt;1&lt;/sup&gt;, Rama Mohan Gupta Vankadari&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Division of Pharmacognosy, Raghavendra Institute of Pharmaceutical Education and Research, Krishnam Reddy Palli cross, Chiyyedu, Anantapuramu-515721, Andhra Pradesh, INDIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Pulla Reddy Institute of Pharmacy, Near Dundigal Air force Academy, Annaram Village, Jinnaram Mandal, Medak- 502313, Andhra Pradesh, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Pulak Majumder</style></author><author><style face="normal" font="default" size="100%">M Paridhavi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Novel Poly‐herbal Formulation Hastens Diabetic Wound Healing with Potent Antioxidant Potential: A Comprehensive Pharmacological Investigation</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetes</style></keyword><keyword><style  face="normal" font="default" size="100%">Poly herbal formulation</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword><keyword><style  face="normal" font="default" size="100%">Wound model</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">324-331</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;strong&gt;Objective&lt;/strong&gt;: Currant investigation was aimed to evaluate the wound healing and antioxidant potentials of the novel Poly-herbal Formulation (PHF) in diabetic rat’s models and &lt;em&gt;in-vitro&lt;/em&gt; antioxidant assays respectively. &lt;strong&gt;Methods&lt;/strong&gt;: The wound models viz., excision, incision and dead space by using wistar strain albino rats were adopted for this investigation. The free radical scavenging assays were employed for investigation of Antioxidant potential in poly herbal formulation. The constraints studied for assessment of wound repair were percentage closing percentage of wound, tensile strength of repaired tissue, breaking strength of granulation tissue and valuation of hydroxyproline content on dried tissue. The histopathological sections of granulation tissues obtained in dead space wound model were studied for the distribution of collagen and other histopathological changes. Four groups were used in this study with six animals each. Group I and Group II acts as normal control and diabetic control whereas Group III and Group IV was used as glibenclamide treated (1mg/kg b.w.) and PHF (500 mg/kg b.w.) treated group respectively. On the other hand the various antioxidant assays like DPPH, scavenging assays, hydrogen peroxide assay etc. were investigated. &lt;strong&gt;Results:&lt;/strong&gt; The PHF has been significantly healing the wounds in diabetic rats within 18 days, while diabetic control rats healed the wound about 86.12% in the same conditions and time. The wound breaking strength and histopathological studies of healed skin was signified the results. Significant (p&amp;lt;0.01) increase in wound breaking strength as well as epithelialization and the level of hydroxyproline was observed in PHF treated animals comparison with diabetic control group. PHF has also shown significant antioxidant potential in &lt;em&gt;in-vitro&lt;/em&gt; assays. &lt;strong&gt;Conclusion&lt;/strong&gt;: All these investigation indicates the significant wound healing and antioxidant potential of PHF in the experimental animal groups in diabetic condition.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">324</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Pulak Majumder&lt;sup&gt;1,&lt;/sup&gt;*, M Paridhavi&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Research scholar, PRIST University, Thanjavour, Tamil Nadu, INDIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Professor and Principal, Rajiv Gandhi Institute of Pharmacy, Trikaripur, Kerala, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Lia Ardiana</style></author><author><style face="normal" font="default" size="100%">Rani Sauriasari</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antidiabetic Activity Studies of White Tea (Camellia sinensis (L.) O. Kuntze) Ethanolic Extracts in Streptozotocin-nicotinamide Induced Diabetic Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antidiabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Camellia sinensis</style></keyword><keyword><style  face="normal" font="default" size="100%">Catechin</style></keyword><keyword><style  face="normal" font="default" size="100%">Hypoglycemic</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword><keyword><style  face="normal" font="default" size="100%">White tea</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/417</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">186-189</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; The high polyphenol content of white tea exhibits antiseptic and antioxidant properties that can prevent free radicals, inhibit oxidative stress and inflammation associated with various diseases such as obesity, diabetes and other degenerative diseases. Oral administration of white tea ethanolic extract (WTE) is expected to use as an alternative in the treatment of diabetes mellitus. &lt;strong&gt;Objective:&lt;/strong&gt; This study aims to evaluate the effect of WTE on reducing fasting blood glucose levels in diabetic rats. Methods: Antidiabetic activity study of white tea extract performed on diabetic Sprague-Dawley male rats induced &lt;em&gt;streptozotocin-nicotinamide&lt;/em&gt; for 14 days of oral administration. The antidiabetic effect compared to normal control, diabetic control, and standard control groups. &lt;strong&gt;Results:&lt;/strong&gt; The administration of WTE for 14 days showed decreased fasting blood glucose level in diabetic rats. The dose of 100 mg/kg BW of WTE has the highest effect on reducing fasting glucose level significantly compared to negative control group (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05). The content of flavonoids, especially catechin compounds are suspected to play a role in lowering fasting blood glucose levels. &lt;strong&gt;Conclusion:&lt;/strong&gt; The administration of WTE for 14 days has potentially antidiabetic activity in diabetic rats induced &lt;em&gt;streptozotocin-nicotinamide&lt;/em&gt;.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">186</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Lia Ardiana, Rani Sauriasari*, Berna Elya&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Faculty of Pharmacy, University of Indonesia, 16424, Depok, INDONESIA.&amp;nbsp;&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ram Niwas Jangir</style></author><author><style face="normal" font="default" size="100%">Gyan Chand Jain</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Evaluation of Antidiabetic Activity of Hydroalcoholic Extract of Cassia fistula Linn. pod in Streptozotocin-Induced Diabetic Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antidiabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Blood glucose</style></keyword><keyword><style  face="normal" font="default" size="100%">Cassia fistula</style></keyword><keyword><style  face="normal" font="default" size="100%">Glycogen</style></keyword><keyword><style  face="normal" font="default" size="100%">Glycosylated Hemoglobin</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">/files/pj-9-5/10.5530pj.2017.5.95/index.html</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">599-606</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Diabetes mellitus (DM) is a global health problem and the incidence of DM is increasing at alarming rate all over the world. Many Indian medicinal plants have been reported to possess potential antidiabetic activity and could play important role in the management diabetes. &lt;strong&gt;Objective:&lt;/strong&gt; The present study aimed to evaluate antidiabetic activities of 70% ethanolic extract of &lt;em&gt;Cassia fistula&lt;/em&gt; pod in streptozotocin-induced diabetic rats. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Diabetes was induced in male Wistar rats by single intraperitoneal injection of streptozotocin (60 mg/kg b.wt.). The diabetic rats were administered orally with &lt;em&gt;C. fistula&lt;/em&gt; pod extract at three different doses (100, 250 and 500 mg/kg b.wt./day) for 60 days. The results were compared with standard drug glibenclamide (5 mg/kg b.wt./day) treated rats. &lt;strong&gt;Results:&lt;/strong&gt; The streptozotocin treated diabetic control rats showed a significant increase in the blood glucose and glycosylated hemoglobin (HbA1c) levels with a concomitant decrease in the body weight and glycogen content in the liver as compared to normal control rats. Oral administration of &lt;em&gt;C. fistula&lt;/em&gt; pod extract (100, 250 and 500 mg/kg b.wt./day) or glibenclamide for 60 days showed significant reduction in the blood glucose and HbA1c levels and an elevation in the body weight and hepatic glycogen content as compared to diabetic control rats. Furthermore, treatment with extract (500 mg/kg b.wt.) also showed improvement of oral glucose tolerance test (OGTT) in diabetic rats. These results were comparable to glibenclamide. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results of present study showed that&lt;em&gt; C. fistula&lt;/em&gt; pod extract possess significant antihyperglycemic activity and supports the traditional use of &lt;em&gt;C. fistula&lt;/em&gt; pod for the treatment of diabetes mellitus.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">599</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ram Niwas Jangir, Gyan Chand Jain&lt;sup&gt;* &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Centre for Advanced Studies, Department of Zoology, University of Rajasthan, Jaipur, Rajasthan, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Nahid Mahmoud Hassan El-Ameen</style></author><author><style face="normal" font="default" size="100%">Manal Mohamed Elhassan Taha</style></author><author><style face="normal" font="default" size="100%">Siddig Ibrahim Abdelwahab</style></author><author><style face="normal" font="default" size="100%">Asaad Khalid</style></author><author><style face="normal" font="default" size="100%">Fatima Elfatih</style></author><author><style face="normal" font="default" size="100%">Mona Awad Kamel</style></author><author><style face="normal" font="default" size="100%">Bassem Yousif Sheikh</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anti-diabetic Properties of Thymoquinone is unassociated with Glycogen Phosphorylase Inhibition</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Diabetes</style></keyword><keyword><style  face="normal" font="default" size="100%">Docking</style></keyword><keyword><style  face="normal" font="default" size="100%">Enzyme</style></keyword><keyword><style  face="normal" font="default" size="100%">Glycogen phosphorylase inhibition</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword><keyword><style  face="normal" font="default" size="100%">Thymoquinone.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">01/2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">406-410</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; &lt;em&gt;Nigella sativa&lt;/em&gt; L. (Black seed), is commonly used by traditional healers as a remedy for more than four thousand years. The antidiabetic property of &lt;em&gt;N. sativa&lt;/em&gt; seeds oil is attributable to the presence of Thymoquinone (TQ). On the other hand many studies have been designed to investigate the possible effects of the TQ in Streptozotocin (STZ) and nicotinamide (NA)-induced diabetes in rats. &lt;strong&gt;Aim of the study: &lt;/strong&gt;The aim of this study was to elucidate the mechanisms underlying the glucose lowering effects of thymoquinone. &lt;strong&gt;Methods:&lt;/strong&gt; &lt;em&gt;In vitro&lt;/em&gt; and &lt;em&gt;in silico&lt;/em&gt; using glycogen phosphorylase (GPa) enzyme assay and docking tools were used. &lt;strong&gt;Results:&lt;/strong&gt; Oral administration of TQ for 60 days, dose dependently improved the glycemic status in STZ-NA induced diabetic rats. GPa activity was measured in the direction of glycogen synthesis by the release of phosphate from glucose-1-phosphate. TQ at a concentration of 0.05 Mm inhibits GPa activity by only 14.9%. &lt;strong&gt;Conclusion:&lt;/strong&gt; These results show that TQ at 60 mg/kg b.w is associated with potential antihyperglycemic effects. Furthermore, anti-diabetic properties of TQ are unassociated with glycogen phosphorylase inhibition.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">406</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Nahid Mahmoud Hassan El-Ameen&lt;sup&gt;1*&lt;/sup&gt;, Manal Mohamed Elhassan Taha&lt;sup&gt;1*&lt;/sup&gt;, Siddig Ibrahim Abdelwahab&lt;sup&gt;1&lt;/sup&gt;, Asaad Khalid&lt;sup&gt;1&lt;/sup&gt;, Fatima Elfatih&lt;sup&gt;2&lt;/sup&gt;, Mona Awad Kamel&lt;sup&gt;1&lt;/sup&gt; and Bassem Yousif Sheikh&lt;sup&gt;3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biomedical Research Unit, Researcher at Medical Research Center, Jazan University, Jazan, Saudi Arabia.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biochemistry Medicinal and Aromatic Plants Research Institute, National Centre for Research, P. O. Box 2420 Khartoum, Sudan.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Surgery, MABL Chair, College of Medicine, Taibah University, Saudi Arabia.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Tushar Kanti Bera,</style></author><author><style face="normal" font="default" size="100%">Kausik Chatterjee,</style></author><author><style face="normal" font="default" size="100%">Debidas Ghosh</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Alpha glucosidase inhibitory activity of hydro-methanolic (2:3) extract of seed of Swietenia mahagoni (L.) Jacq</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">a-glucosidase</style></keyword><keyword><style  face="normal" font="default" size="100%">Postprandial hyperglycemia</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword><keyword><style  face="normal" font="default" size="100%">Total flavonoids</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">18th Feb,2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">63-69</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objectives:&lt;/strong&gt; Present study investigated the effect of hydro-methanolic extract of seed of Swietenia mahagoni (HMESM) on a-glucosidase inhibition in normal and streptozotocin-induced diabetic rats. &lt;strong&gt;Methods:&lt;/strong&gt; Oral carbohydrate tolerance tests were performed in 16h fasted normal and diabetic rats loaded with starch or sucrose or glucose at the dose of 3g/kg, 15min after administration of 250 (S1), 500 (S2), 1000 (S3) mg/kg of HMESM, vehicle (control),or pretreatment at the dose of 10 mg/kg of acarbose (Acar). Blood samples were analyzed for glucose levels at 0, 30&lt;sup&gt;th&lt;/sup&gt;, 60&lt;sup&gt;th&lt;/sup&gt;, and 120&lt;sup&gt;th&lt;/sup&gt; min after respective treatments and the peak blood glucose (PBG) levels and area under the curves (AUC) were determined. &lt;strong&gt;Results:&lt;/strong&gt; Results demonstrated that 500 mg, 1000 mg/kg of HMESM reduced and prolonged the PBG and decreased AUC simultaneously after starch and sucrose loading in normal and diabetic rats. Similarly acarbose also reduce the sucrose and starch induced blood glucose excursion, whereas it had no peak blood glucose suppressive effect after exogenous glucose load in both normal and diabetic rats. On the other hand, phytochemical study of the said extract revealed that it is rich in phenolic compounds (46.25 mg of gallic acid equivalent/g of extract) and flavonoids (231.72 mg of quercetin equivalent/g of the extract), which may may responsible for pharmacological activities. &lt;strong&gt;Conclusion: &lt;/strong&gt;The HMESM may have PBG suppressive effect in post-carbohydrate challenged state as evidenced by reduced PBG and AUC. This suggest that HMESM may be used effectively as a safer alternative to control postprandial hyperglycemia especially in pre-diabetic and diabetic patients.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Key words:&lt;/strong&gt; Streptozotocin,∝-glucosidase, Postprandial hyperglycemia, Total flavono.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Tushar Kanti Bera,&lt;sup&gt;1,2&lt;/sup&gt; Kausik Chatterjee&lt;sup&gt;1&lt;/sup&gt; and Debidas Ghosh&lt;sup&gt;1,*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Bio-Medical Laboratory Science and Management, Vidyasagar University, Midnapur-721 102, West Bengal, India&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmaceutical Division, Southern Health Improvement Samity (SHIS), South 24 Paraganas, Bhangar-743 502, West Bengal, India.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Guenzet Akila,</style></author><author><style face="normal" font="default" size="100%">Krouf Djamil,</style></author><author><style face="normal" font="default" size="100%">Berzou Saadia</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Portulaca oleracea extract increases lecithin:cholesterol acyltransferase and paraoxonase 1 activities and enhances reverse cholesterol transport in streptozotocin-induced diabetic rat</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">apo A-I</style></keyword><keyword><style  face="normal" font="default" size="100%">Cholesterol</style></keyword><keyword><style  face="normal" font="default" size="100%">LCAT</style></keyword><keyword><style  face="normal" font="default" size="100%">lipoprotein peroxidation</style></keyword><keyword><style  face="normal" font="default" size="100%">PON1</style></keyword><keyword><style  face="normal" font="default" size="100%">Portulaca oleracea</style></keyword><keyword><style  face="normal" font="default" size="100%">Rats</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">8th April 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">1-9</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Plant extracts are generally assumed to be more acceptable and less hazardous than synthetic compounds and could be alternative antidiabetic treatments. &lt;em&gt;Portula caoleracea&lt;/em&gt; has been used as one of the traditional edible and medicinal plant in Algeria to treat diabetes. The aim of the present study was to determine the effects of lyophilized aqueous extract of &lt;em&gt;Portulaca oleracea&lt;/em&gt; on high-density lipoproteins composition, paraoxonase (PON1) and lecithin:cholesterol acyltransferase (LCAT) activities in streptozotocin-induced diabetic rat. &lt;strong&gt;Methods:&lt;/strong&gt; Diabetes was induced intraperitonially by a single injection of streptozotocin (STZ) (60mg/kg bw). Twelve diabetic rats, weighing 263&amp;plusmn;5g, were divided into two groups fed a casein diet supplemented or not with&lt;em&gt; Portulaca oleracea&lt;/em&gt; extract (1g/kg bw), for 4 weeks.&lt;strong&gt; Results:&lt;/strong&gt; At d28, in&lt;em&gt; Portulaca oleracea&lt;/em&gt; treated vs untreated diabetic group, glycemia, serum total cholesterol (TC), triacylglycerols (TG) and phospholipids (PL) concentrations were decreased significantly (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05). The hypolipidemic effect induced by &lt;em&gt;Portulaca oleracea&lt;/em&gt; extract was due to the reduction of total cholesterol (TC) in LDL-HDL&lt;sub&gt;1&lt;/sub&gt; (-51%) and C-HDL&lt;sub&gt;3&lt;/sub&gt; (-21%).&lt;em&gt; Portulaca oleracea&lt;/em&gt; treatment improved PON1 and LCAT activities by 48%. HDL3-UC (acyl group acceptor) and -PL (enzyme substrate) were diminished respectively by 47% and 82%, whereas HDL&lt;sub&gt;2&lt;/sub&gt;-CE concentrations (product of LCAT reaction) were increased by 44%. Moreover, HDL-C levels were found to be positively correlated with PON1 activity (r=0.96, &lt;em&gt;p&lt;/em&gt;&amp;lt;0.05). Serum, LDL-HDL&lt;sub&gt;1&lt;/sub&gt;, HDL&lt;sub&gt;2&lt;/sub&gt; and HDL&lt;sub&gt;3&lt;/sub&gt; TBARS levels were respectively, 2.9-, 2.6-, 2.4- and 2.8-fold lower in &lt;em&gt;Portulaca oleracea&lt;/em&gt; treated than untreated diabetic groups. &lt;strong&gt;Conclusion:&lt;/strong&gt; These findings reflect the potential antihyperglycemic and hypolipidemic of &lt;em&gt;Portulaca oleracea&lt;/em&gt; extract, in STZ-induced diabetic rat. Moreover,&lt;em&gt; Portulaca oleracea&lt;/em&gt; extract restores PON1 and ameliorates the reverse cholesterol transport (RCT) by enhancing LCAT activity, therefore could prevent many diabetic complications by reducing dyslipidemia and oxidative damage.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words: &lt;/strong&gt;Rats, Streptozotocin, &lt;em&gt;Portulaca oleracea&lt;/em&gt;, Cholesterol, PON1, LCAT, apo A-I, lipoprotein peroxidation.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Guenzet Akila, Krouf Djamil and Berzou Saadia&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;Laboratoire de Nutrition Clinique et M&amp;eacute;tabolique, D&amp;eacute;partement de Biologie, Facult&amp;eacute; des Sciences de la Nature et de la Vie. Universit&amp;eacute; d&amp;rsquo;Oran. 31100 Oran, Alg&amp;eacute;rie.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">C.Elanchezhiyan</style></author><author><style face="normal" font="default" size="100%">K.Kumaravel</style></author><author><style face="normal" font="default" size="100%">Ahmad bhat</style></author><author><style face="normal" font="default" size="100%">S.Sethupathy</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Protective role of  Helicteres isora plant extract on plasma and tissue glycoprotein components in streptozotocin induced hyperglycemic rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Diabetes</style></keyword><keyword><style  face="normal" font="default" size="100%">Helicteres isora</style></keyword><keyword><style  face="normal" font="default" size="100%">Plasma Glycoproteins</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">26th May 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">86-91</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;The present investigation was carried out to evaluate the protective role of &lt;em&gt;Helicteres &lt;/em&gt;isora plant extract on glycoprotein metabolism in streptozotocin (STZ) induced type 2 diabetic rats. &lt;em&gt;Helicteres isora &lt;/em&gt;plant extract was administered orally (200 mg/kg body weight) for 40 days to normal and diabetic rats. The effects of Helicteres isora plant extract on plasma and tissue glycoproteins (hexose, hexosamine, sialic acid and fucose) were determined. The levels of plasma glycoproteins containing hexose, hexosamine, sialic acid and fucose were significantly increased in diabetic rats when compared with normal control rats. There was a significant decrease in the level of sialic acid and elevated levels of hexose, hexosamine and fucose in the liver and kidney of STZ induced diabetic rats. On oral administration of&lt;em&gt; Helicteres&lt;/em&gt; isora plant extract to diabetic rats showed decreased levels of plasma glycoproteins. The level of tissue sialic acid was increased whereas the levels of tissue hexose, hexosamine and fucose were reversed to near normal. The present study indicates that the&lt;em&gt; Helicteres&lt;/em&gt; isora plant extract possesses a significant protective effect on glycoprotein metabolism in addition to its anti-diabetic effect.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words:&lt;/strong&gt;&lt;em&gt;Helicteres &lt;/em&gt;isora, Diabetes, Plasma Glycoproteins, Streptozotocin.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;C Elanchezhiyan&lt;sup&gt;*1&lt;/sup&gt;, K Kumaravel&lt;sup&gt;2&lt;/sup&gt;, Bilal Ahmad Bhat&lt;sup&gt;1&lt;/sup&gt; and S Sethupathy&lt;/strong&gt;&lt;sup&gt;&lt;strong&gt;3&lt;/strong&gt;&lt;/sup&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Zoology, Annamalai University, Annamalainagar-608002, Tamil Nadu, India&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Marine Biotechnology, CAS in Marine Biology, Annamalai University, Parangipettai&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Division of Medical Biochemistry, RMMCH, Annamalai University, Annamalainagar-608002.&lt;/p&gt;</style></auth-address></record></records></xml>