<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Friday Super Nova</style></author><author><style face="normal" font="default" size="100%">Shofa Chasani</style></author><author><style face="normal" font="default" size="100%">Atina Hussanna</style></author><author><style face="normal" font="default" size="100%">Siti Thomas Zulaikhah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Tender Coconut Water Inhibits the Process of Lipid Peroxidation, Reduce Glucose Levels and Increase Plasma Insulin in Pregnant Diabetic Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">GDM</style></keyword><keyword><style  face="normal" font="default" size="100%">Glucose</style></keyword><keyword><style  face="normal" font="default" size="100%">Insulin plasma</style></keyword><keyword><style  face="normal" font="default" size="100%">Lipid peroxidation</style></keyword><keyword><style  face="normal" font="default" size="100%">Tender coconut water (TCW)</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February  2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">162-167</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Diabetes during pregnancy or Gestational Diabetes Mellitus&lt;em&gt; &lt;/em&gt;(GDM) causes oxidative stress and have bad effect for mother and baby, risk of abortion, still birth, premature and preeclampsia. GDM can be prevented by monitoring the glucose level and providing rich antioxidants meals. TCW is a nutritious healthy drink rich in antioxidants, diet rich in antioxidants promotes better health, Inhibits lipid peroxidation and enhances the total antioxidant status. &lt;strong&gt;Aim and Objectives: &lt;/strong&gt;This research to investigate the effect of tender coconut water can prevent lipid peroxidation, reduce glucose levels and increase insulin plasma level on pregnant diabetic rats. &lt;strong&gt;Material and Methods: &lt;/strong&gt;Experimental study by post test only control group design, population of pregnant wistar strain rats. Twenty four samples used in this study were randomly divided into 4 groups, K1 (pregnant rats), K2 (pregnant rats+diabetic), K3 (pregnant rats+diabetic+ glibenklamid 0.23 mg/kg BW ) and K4 (pregnant rats+diabetic+TCW 8mL/200grBW). Diabetes Mellitus were induced using Streptozotocin (STZ) 65mg/kgBW and Nicotinamid 230 mg/kgBW. Data on insulin plasma, glucose and MDA levels were analyzed using One Way Anova with significant level 0.05.&lt;strong&gt; Result: &lt;/strong&gt;The results showed that the average insulin plasma levels in group 2 decreased compared to group 1 , in group 3 and 4 it increased compared to group 2. Average glucose and MDA levels in group 2 increased compared to group 1 , in group 3 and 4 it decreased compared to group 2. The results of the analysis has the p values 0.000 (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05). &lt;strong&gt;Conclusion:&amp;nbsp;&lt;/strong&gt;TCW can inhibit the process of lipid peroxidation, reduce glucose levels, increase insulin plasma levels and in pregnant diabetic rats.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">162</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Friday Super Nova&lt;sup&gt;1&lt;/sup&gt;, Shofa Chasani&lt;sup&gt;2&lt;/sup&gt;, Atina Hussanna&lt;sup&gt;2&lt;/sup&gt;, Siti Thomas Zulaikhah&lt;sup&gt;2,&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Student Program Master of Biomedical Science Faculty of Medicine Sultan Agung Islamic University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Lecturers Program Master of Biomedical Science Faculty of Medicine Sultan Agung Islamic University, INDONESIA&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Welly Ratwita</style></author><author><style face="normal" font="default" size="100%">Elin Yulinah Sukandar</style></author><author><style face="normal" font="default" size="100%">I Ketut Adnyana</style></author><author><style face="normal" font="default" size="100%">Neng Fisheri Kurniati</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Alpha Mangostin and Xanthone Activity on Fasting Blood Glucose, Insulin and Langerhans Islet of Langerhans in Alloxan Induced Diabetic Mice</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Fasting blood glucose</style></keyword><keyword><style  face="normal" font="default" size="100%">Insulin plasma</style></keyword><keyword><style  face="normal" font="default" size="100%">Langerhans</style></keyword><keyword><style  face="normal" font="default" size="100%">Xanthone</style></keyword><keyword><style  face="normal" font="default" size="100%">α-mangostin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">64-68</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Objective:&lt;/strong&gt; This research elaborated role of alpha mangostin and xanthone on fasting blood glucose, insulin and langerhans islet in alloxan induced diabetic mice. &lt;strong&gt;Methods:&lt;/strong&gt; Fasting blood glucose, insulin and langerhans islet test were conducted using male &lt;em&gt;Mus musculus&lt;/em&gt; mice, divided into 10 groups randomly, which were normal, control (alloxan induced only), glibenclamide, various doses of α-mangostin and xanthone (5, 10, 20 mg/kgbw). Mice were treated for 21 days. Overnight-fasted mice (12 h) were sacrificed by cervical decapitation on day 21st, following the ethical norms granted by the ethics committee. Fasting blood glucose and insulin plasma were checked. Pancreatic tissues were excised from sacrificed animals, and then fixed in 10 % (v/v) neutral buffered formalin. Histologic observations for Langerhans area were performed after staining using Gomori staining method. &lt;strong&gt;Results:&lt;/strong&gt; The effects of alpha mangostin and xanthone on fasting blood glucose different significantly to control, and were not significantly different from glibenclamide and metformin. Increasing alpha mangostin/xanthone dose from 5 mg/kgbw to 20 mg/bw also did not cause significant differences, although the best results were obtained at a dose of 20 mg/kgbw. Insulin plasma analize showed that there were no significant difference between alpha mangostin/xanthone to normal group, except xanthone 10 mg/kgbw. Langerhans area showed significant difference between alpha mangostin/xanthone to control group. But there’s still had significant difference if we compare to glibenclamid/metformin group.&lt;strong&gt; Conclusion:&lt;/strong&gt; Alpha mangostin and xanthone are two substances that showed antidiabetic effect on fasting blood glucose level, insulin plasma and Langerhans islet.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">64</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Welly Ratwita&lt;sup&gt;*,1&lt;/sup&gt;,&amp;nbsp;Elin Yulinah Sukandar&lt;sup&gt;2&lt;/sup&gt; I Ketut Adnyana&lt;sup&gt;2&lt;/sup&gt; Neng Fisheri Kurniati&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, Jenderal Achmad Yani University-Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Bandung Institute of Technology, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Departement of Pharmacology and Clinical Pharmacy, Bandung Institute of Technology, INDONESIA.&lt;/p&gt;
</style></auth-address></record></records></xml>