<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ana Fresia</style></author><author><style face="normal" font="default" size="100%">Gusbakti Rusip</style></author><author><style face="normal" font="default" size="100%">Ade Indra Mukti</style></author><author><style face="normal" font="default" size="100%">Ali Napiah Nasution</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Effectiveness of Enteral Administration of Binahong Leaf Extract (Anredera cordifolia (Tenore) Steenis) on Blood Glucose Levels, MDA, and NGF in Wistar Rats with Diabetic Neuropathy Model</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anredera cordifolia</style></keyword><keyword><style  face="normal" font="default" size="100%">blood glucose levels</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetic neuropathy</style></keyword><keyword><style  face="normal" font="default" size="100%">Malondialdehyde</style></keyword><keyword><style  face="normal" font="default" size="100%">Nerve Growth Factor</style></keyword><keyword><style  face="normal" font="default" size="100%">Wistar Rats</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2026</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2026</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">18</style></volume><pages><style face="normal" font="default" size="100%">107-112</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Chronic hyperglycemia causes oxidative stress in the peripheral nervous system, which leads to the development of diabetic neuropathy. Free radicals initiate lipid peroxidation of membranes and produce malondialdehyde (MDA). Reduced Nerve Growth Factor (NGF) in diabetes indicates significant neuronal abnormalities. Binahong (Anredera cordifolia (Ten.) Steenis) belongs to the Basellaceae family and possesses therapeutic effects, making it a promising herbal remedy for the development of treatments for diabetic neuropathy. &lt;strong&gt;Objective: &lt;/strong&gt;To determine the effectiveness of binahong leaf extract (Anredera cordifolia (Tenore) Steenis) in lowering blood sugar and MDA levels and increasing NGF in Wistar rats with diabetic neuropathy. &lt;strong&gt;Methods: &lt;/strong&gt;This study was an experimental study using rats with a randomized control trial with a post-test control only design. The study population consisted of 36 Wistar rats divided into 6 groups randomly, which were then induced with diabetic neuropathy via streptozotocin injection at 65 mg/kg. Complete data collection was conducted, followed by blood glucose levels, MDA, and NGF measurements, and data analysis. &lt;strong&gt;Results:&lt;/strong&gt; There were significant differences (p&amp;lt;0.05) in blood glucose levels, MDA, and NGF between the normal group, the 50 mg/kg binahong leaf extract group, the 100 mg/ kg radish extract group, and the 200 mg/kg group compared to the negative control group. This indicates that binahong leaf extract, starting at a dose of 50 mg/kg, can reduce blood glucose levels and MDA while increasing NGF. &lt;strong&gt;Conclusion:&lt;/strong&gt; Binahong leaf extract (Anredera cordifolia (Tenore) Steenis) is effective in lowering blood glucose levels and MDA levels while increasing NGF in a rat model of diabetic neuropathy.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">107</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ana Fresia&lt;sup&gt;1,2&lt;/sup&gt;, Gusbakti Rusip&lt;sup&gt;2,3*&lt;/sup&gt;, Ade Indra Mukti&lt;sup&gt;4&lt;/sup&gt;, Ali Napiah Nasution&lt;sup&gt;2,3&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Neurology, Faculty of Medicine, Universitas Prima Indonesia, Medan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Doctoral in Medicine Program, Faculty of Medicine, Universitas Prima Indonesia, Medan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Family Medicine, Faculty of Medicine, Universitas Prima Indonesia, Medan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Division of Urology, Department of Surgery, Faculty of Medicine, Universitas Prima Indonesia, Medan, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sara Al Ayoubi, Karim Raafat</style></author><author><style face="normal" font="default" size="100%">Abdalla El-Lakany</style></author><author><style face="normal" font="default" size="100%">Maha Aboul-Ela</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Phytochemical Investigation of Psoralea bituminosa L. and its Anti-Diabetic Potentials</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antidiabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetic neuropathy</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oil</style></keyword><keyword><style  face="normal" font="default" size="100%">Psoralea bituminosa</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">841-853</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; &lt;em&gt;Psoralea bituminosa&lt;/em&gt; L. (Fabaceae), is a very important medicinal plant, used in traditional medicine in Europe, Asia, and America, and in Africa for, its antiseptic, antihyperglycemic and anti-oxidative potentials. The objective of this study is to investigate the potential of &lt;em&gt;Psoralea bituminosa&lt;/em&gt; (&lt;em&gt;Pbt&lt;/em&gt;.) in the management of diabetes and diabetic &amp;ndash; induced thermal hyperalgesia. Moreover, this study aimed also to investigate the volatile oil constituents of Pbt. growing in Lebanon utilizing GC-MS method. &lt;strong&gt;Methods:&lt;/strong&gt; Blood glucose level (BGL) was measured using gluco-meter while diabetic-induced thermal hyperplasia of Pbt. growing in Lebanon was measured using tail flick and hot plate methods. Antioxidant was measured using DPPH free radicals method. Volatile oil of fresh and dried aerial parts of &lt;em&gt;Pbt&lt;/em&gt;. was analyzed using GC-MS.&lt;strong&gt; Results:&lt;/strong&gt; The result of study conducted on Lebanese &lt;em&gt;Pbt&lt;/em&gt;. revealed that acute anti-diabetic activity of &lt;em&gt;Pbt.&lt;/em&gt; in the 3 extracts subjected a decrease in BGL ranging between 34% to 38.5%. In subchronic anti-diabetic activity of Pbt. BGL dropped in range 19% to 44%. Moreover, Pbt. extract showed 1.7% to 13.6%increase in body weight at all doses with respect to 8&lt;sup&gt;th&lt;/sup&gt; day. On the other hand, alloxan diabetic induced mice reported melioration by 63.8% to 86.3% on the 8th week alloxan after injection in diabetic &amp;ndash; induced thermal hyperalgesia hotplate latency method. Nevertheless, a marked improvement in tail flick latency on the 8&lt;em&gt;th&lt;/em&gt; week after alloxan injection by 22.7 % to 48.6 %. &lt;em&gt;Pbt.&lt;/em&gt; extract revealed DPPH radical decreases at 82.6% at concentration of 100 mg/mL, respectively. Total flavonoid content measured of Pbt. was 135.83 mg/g while total phenolic content showed 217.48 mg/g. &lt;strong&gt;Conclusion:&lt;/strong&gt;&amp;nbsp;&lt;em&gt;Psoralea &lt;/em&gt;&lt;em&gt;bituminosa&amp;nbsp;&lt;/em&gt; showed a significant effect in the management of diabetes and neuropathic pain conditions and limiting expected side-effects, which might be used as a future antidiabetic therapy.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">841</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Sara Al Ayoubi, Karim Raafat&lt;sup&gt;*&lt;/sup&gt;,&amp;nbsp;Abdalla El- Lakany,&amp;nbsp;Maha Aboul-Ela &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmaceutical Sciences, Faculty of Pharmacy, Beirut Arab University, Beirut, LEBANON.&lt;/p&gt;</style></auth-address></record></records></xml>