<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Judy D. V. Perez</style></author><author><style face="normal" font="default" size="100%">Chien Chang Shen</style></author><author><style face="normal" font="default" size="100%">Consolacion Y. Ragasa</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Chemical Constituents of Cymodocea rotundata Asch. and Schweinf</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Chlorophyll</style></keyword><keyword><style  face="normal" font="default" size="100%">Cymodocea rotundata</style></keyword><keyword><style  face="normal" font="default" size="100%">Cymodoceaceae</style></keyword><keyword><style  face="normal" font="default" size="100%">Stigmasterol.</style></keyword><keyword><style  face="normal" font="default" size="100%">β-sitosterol</style></keyword><keyword><style  face="normal" font="default" size="100%">β-sitosteryl-3β-glucopyranoside-6′-Ofatty acid esters</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/639</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">620-621</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; &lt;em&gt;Cymodocea rotundata &lt;/em&gt;Asch. and Schweinf, a widespread seagrass with reported antimicrobial activity, was investigated for its chemical constituents. &lt;strong&gt;Methods:&lt;/strong&gt; The compounds were isolated by silica gel chromatography and identified by NMR spectroscopy. &lt;strong&gt;Results:&lt;/strong&gt; This study has led to the isolation of &amp;beta;-sitosteryl-3&amp;beta;-glucopyranoside-6&amp;prime;-&lt;em&gt;O&lt;/em&gt;-fatty acid esters (&lt;strong&gt;1&lt;/strong&gt;), chlorophyll a (&lt;strong&gt;2&lt;/strong&gt;) and a mixture of &amp;beta;-sitosterol (&lt;strong&gt;3a&lt;/strong&gt;) and stigmasterol (&lt;strong&gt;3b&lt;/strong&gt;) in about 1:1 ratio from the dichloromethane extract of &lt;em&gt;C. rotundata&lt;/em&gt;. &lt;strong&gt;Conclusion:&lt;/strong&gt; This is the first report on the isolation of &lt;strong&gt;1-3b&lt;/strong&gt; from &lt;em&gt;C. rotundata&lt;/em&gt;. Compounds &lt;strong&gt;2-3b&lt;/strong&gt; were reported to exhibit antibacterial activity and may be partly responsible for the reported antimicrobial activity of the &lt;em&gt;C. rotundata&lt;/em&gt; extract.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">620</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Judy D.V. Perez&lt;sup&gt;1,2&lt;/sup&gt;, Chien Chang Shen&lt;sup&gt;3&lt;/sup&gt;, Consolacion Y. Ragasa&lt;/strong&gt;&lt;sup&gt;&lt;strong&gt;1,4*&lt;/strong&gt; &lt;/sup&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Chemistry Department, De La Salle University, 2401 Taft Avenue, Manila 1004, PHILIPPINES.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Natural Science Department, College of Arts and Sciences, Ateneo de Naga University, P. Santos St, Pe&amp;ntilde;afrancia, Naga, Camarines Sur, PHILIPPINES.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;National Research Institute of Chinese Medicine, Ministry of Health and Welfare, 155-1, Li-Nong St., Sec. 2, Taipei 112, TAIWAN.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Chemistry Department, De La Salle University Science and Technology Complex Leandro V. Locsin Campus, Bi&amp;ntilde;an City, Laguna 4024, PHILIPPINES.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Allan Patrick G. Macabeo</style></author><author><style face="normal" font="default" size="100%">Christopher A. Lee</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Sterols and triterpenes from the non-polar antitubercular fraction of Abutilon indicum</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Abutilon indicum</style></keyword><keyword><style  face="normal" font="default" size="100%">Antitubercular</style></keyword><keyword><style  face="normal" font="default" size="100%">Malvaceae</style></keyword><keyword><style  face="normal" font="default" size="100%">Squalene</style></keyword><keyword><style  face="normal" font="default" size="100%">Stigmasterol.</style></keyword><keyword><style  face="normal" font="default" size="100%">β-amyrin 3-palmitate</style></keyword><keyword><style  face="normal" font="default" size="100%">β-sitosterol</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">26th May 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">49-52</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt;&lt;em&gt;Abutilon indicum Sweet&lt;/em&gt; (Malvaceae) is used in Filipino folk medicine as demulcent, diuretic, sedative, aphrodisiac and antidiabetic remedy. It is also effective in the treatment of leprosy. It is also used as a laxative for patients having hemorrhoids and in the treatment of coughs, puerperal disease, urinary disorders, chronic dysentery and fever. &lt;strong&gt;Methods:&lt;/strong&gt; Air-dried powdered leaves of &lt;em&gt;A. indicum&lt;/em&gt; were initially extracted with DCM-methanol (1:1) to afford a crude extract which was fractionated on a silica gel column to afford four fractions. The first fraction which showed antimycobacterial activity was further chromatographed in a silica gel column to afford bioactive fractions from which four compounds were obtained. The crude extract, fractions and isolated compounds were screened for their inhibitory effect against &lt;em&gt;Mycobacterium tuberculosis&lt;/em&gt; H&lt;sub&gt;37&lt;/sub&gt;Rv (ATCC) using the colorimetric Microplate Alamar Blue Assay (MABA) method. &lt;strong&gt;Results: &lt;/strong&gt;The fractions obtained after silica gel chromatography of the crude DCMmethanol (1:1) revealed the first fraction (MIC=64 mg/mL) to exert the highest inhibition against &lt;em&gt;M. tuberculosis&lt;/em&gt; H&lt;sub&gt;37&lt;/sub&gt;Rv. Further separation of this fraction afforded sub-fractions with moderately strong inhibitory activity against the test organism (MIC up to 64 mg/mL). Chromatographic purification of sub-fraction 1 afforded four compounds which were spectroscopically identified as &amp;beta;-amyrin 3-palmitate (1), squalene (2) and a 1:1 mixture of the sterols &amp;beta;-sitosterol (3) and stigmasterol (4). Evaluation of the antimycobacterial activity of 1&amp;ndash;4 showed insignificant inhibitory activity against the test organism (MIC = &amp;gt;128 mg/mL). &lt;strong&gt;Conclusion:&lt;/strong&gt; The present results demonstrate the potential of &lt;em&gt;Abutilon indicum&lt;/em&gt; as a plant source of compounds that may exhibit promising antituberculosis activity. While the known compounds isolated for this plant did not show antimycobacterial activity, the obtained results are considered sufficient reason for further study to isolate the metabolites from &lt;em&gt;A. indicum&lt;/em&gt; responsible for the antitubercular activity.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words:&lt;/strong&gt;&lt;em&gt;Abutilon indicum&lt;/em&gt;, Malvaceae, antitubercular, squalene, &amp;beta;-amyrin 3-palmitate, &amp;beta;-sitosterol, stigmasterol.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Allan Patrick G. Macabeo&lt;sup&gt;a,b,*&lt;/sup&gt; and Christopher A. Lee&lt;/strong&gt;&lt;sup&gt;&lt;strong&gt;a&lt;/strong&gt;&lt;/sup&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;a&lt;/sup&gt;Organic Synthesis and Phytochemistry Laboratory, Research Center for the Natural and Applied Sciences, University of Santo Tomas, Espana St., Manila 1015, Philippines&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;b&lt;/sup&gt;Institutf&amp;uuml;rOrganischeChemie, Universit&amp;auml;t Regensburg, Universit&amp;auml;tsstrasse 31, 93053 Regensburg, Germany.&lt;/p&gt;</style></auth-address></record></records></xml>