<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Lakshmi.T</style></author><author><style face="normal" font="default" size="100%">Rajendran.R</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">In vitro Acetyl cholinesterase inhibitory assay of Acacia catechu Willd ethanolic seed extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acacia catechu seed</style></keyword><keyword><style  face="normal" font="default" size="100%">Acetyl cholinesterase inhibitor</style></keyword><keyword><style  face="normal" font="default" size="100%">Alzheimer’s disease</style></keyword><keyword><style  face="normal" font="default" size="100%">Spectrophotometric analysis.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">9th June 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">1-1</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Aim &amp;amp; objective:&lt;/strong&gt; The aim of this study was to evaluate acetyl cholinesterase inhibitory activity of &lt;em&gt;Acacia catechu&lt;/em&gt; ethanolic seed extract to introduce a new source for management of Alzheimer&amp;rsquo;s disease. &lt;strong&gt;Background&lt;/strong&gt;: Alzheimer&amp;rsquo;s disease is a complex, multifactorial, progressive, neurodegenerative disease primarily affecting the elderly population and is estimated to account for 50&amp;ndash;60% of dementia cases in persons over 65 years of age. It is likely that the inhibition of acetyl cholinesterase by&lt;em&gt; Acacia catechu&lt;/em&gt; ethanolic seed extract that is rich in flavonoids and antioxidants may aid in the protection of neurodegenerative disorders and ultimately Alzheimer&amp;#39;s disease. &lt;strong&gt;Methods:&lt;/strong&gt; Anti cholinesterase activity is determined by adopting &lt;em&gt;In vitro&lt;/em&gt; standard protocol. &lt;strong&gt;Results:&lt;/strong&gt; According to the obtained results, the inhibitory activity (IC&lt;sub&gt;50&lt;/sub&gt; values, &amp;mu;g /ml) of extracts was 204.38 &amp;plusmn; 2.54 &amp;micro; g/ml. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results indicated and confirmed the traditional use of &lt;em&gt;Acacia catechu&lt;/em&gt; ethanolic seed extract for management of central nervous system disorders. It showed the moderate activity in inhibition of acetyl cholinesterase at various concentrations. However, further investigations on identification of active components in the extracts are needed.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words&lt;/strong&gt;: &lt;em&gt;Acacia catechu&lt;/em&gt; seed, Acetyl cholinesterase inhibitor, Alzheimer&amp;rsquo;s disease, spectrophotometric analysis.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Lakshmi. T &lt;sup&gt;*1&lt;/sup&gt;, Rajendran. R &lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Assistant professor ,Department of Pharmacology ,Saveetha Dental College &amp;amp; Hospitals, Chennai, India.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Green Chem Herbal Extracts &amp;amp; Formulations,Bangalore,India.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Lakshmi Thangavelu</style></author><author><style face="normal" font="default" size="100%">Rajendran Ramasamy</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">In vitro Acetyl Cholinesterase Inhibitory assay of Acacia catechu Willd Ethanolic Seed Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acacia catechu seed</style></keyword><keyword><style  face="normal" font="default" size="100%">Acetyl cholinesterase inhibitor</style></keyword><keyword><style  face="normal" font="default" size="100%">Alzheimer’s disease</style></keyword><keyword><style  face="normal" font="default" size="100%">Neurodegenerative</style></keyword><keyword><style  face="normal" font="default" size="100%">Spectrophotometric analysis.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">01/2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">280-282</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Aim &amp;amp; objective:&lt;/strong&gt; The aim of this study was to evaluate acetyl cholinesterase inhibitory activity of &lt;em&gt;Acacia catechu &lt;/em&gt;ethanolic seed extract to introduce a new source for management of Alzheimer&amp;rsquo;s disease. &lt;strong&gt;Background:&lt;/strong&gt; Alzheimer&amp;rsquo;s disease is a complex, multifactorial, progressive, neurodegenerative disease primarily affecting the elderly population and is estimated to account for 50&amp;ndash;60% of dementia cases in persons over 65 years of age. It is likely that the inhibition of acetyl cholinesterase by &lt;em&gt;Acacia catechu&lt;/em&gt; ethanolic seed extract that is rich in flavonoids and antioxidants may aid in the protection of neurodegenerative disorders and ultimately Alzheimer&amp;rsquo;s disease. &lt;strong&gt;Methods:&lt;/strong&gt; Anti cholinesterase activity is determined by adopting &lt;em&gt;In vitro &lt;/em&gt;standard protocol. &lt;strong&gt;Results:&lt;/strong&gt; According to the obtained results, the inhibitory activity (IC&lt;sub&gt;50&lt;/sub&gt; values, &amp;mu;g /ml) of extracts was 204.38 &amp;plusmn; 2.54 &amp;mu;g/ ml. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results indicated and confirmed the traditional use of &lt;em&gt;Acacia catechu&lt;/em&gt; ethanolic seed extract for management of central nervous system disorders. It showed the moderate activity in inhibition of acetyl cholinesterase at various concentrations. However, further investigations on identification of active components in the extracts are needed.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">280</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Lakshmi Thangavelu&lt;sup&gt;*1&lt;/sup&gt; and Rajendran Ramasamy&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, Saveetha Dental College and Hospitals, Chennai, India.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Green Chem Herbal Extracts and Formulations, Bangalore, India.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Thangavelu Lakshmi</style></author><author><style face="normal" font="default" size="100%">Rajendran Ramasamy</style></author><author><style face="normal" font="default" size="100%">Rathinam Thirumalaikumaran</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Preliminary Phytochemical analysis and In vitro Antioxidant, FTIR Spectroscopy, Anti-diabetic activity of Acacia catechu ethanolic seed extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acacia catechu seed</style></keyword><keyword><style  face="normal" font="default" size="100%">Alpha glucosidase</style></keyword><keyword><style  face="normal" font="default" size="100%">Alpha-amylase</style></keyword><keyword><style  face="normal" font="default" size="100%">Antidiabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">FTIR Spectroscopy</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Nov-Dec 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">356-362</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; To evaluate the preliminary phytochemical analysis and in vitro antioxidant activity, anti-diabetic effect of ethanolic seed extract of Acacia catechu against the alpha amylase and alpha glucosidase digestive enzymes in the pancreas and small intestine. &lt;strong&gt;Methods:&lt;/strong&gt; Preliminary phytochemical analysis was done by adopting the method of Evans. Antioxidant assay is performed by DPPH, ABTS and FRAP assay, Anti diabetic activity was determined by modified method of miller, the extract at different concentrations was tested for mammalian alpha amylase and alpha glucosidase enzyme inhibitory assay under the controlled experimental conditions and subjected to determination of absorbance. &lt;strong&gt;Results: &lt;/strong&gt;The present study reveals the presence of few secondary metabolites and the extract exhibits potent Antioxidant activity and a concentration dependent inhibition of Alpha amylase and Alpha glucosidase.&lt;strong&gt; Conclusion:&lt;/strong&gt; From the present study it can be concluded that ethanolic seed extract of Acacia catechu possessed marked in vitro antioxidant and anti-diabetic effect. The effect was plausibly due to the presence of phenolic contents of Acacia catechu&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">356</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Thangavelu Lakshmi&lt;sup&gt;*1&lt;/sup&gt;, Rajendran Ramasamy&lt;sup&gt;2&lt;/sup&gt; and Rathinam Thirumalaikumaran&lt;sup&gt;3&lt;/sup&gt; &lt;/strong&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, Saveetha Dental College and Hospitals, Chennai, India. 2Department of R and D, Green Chem Herbal Extracts and Formulations, Bangalore, India. 3Department of Pharmacognosy, Faculty of Pharmacy, Sree Ramachandra Medical College and Research Institute, chennai, India.&lt;/p&gt;</style></auth-address></record></records></xml>