<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rina Masadah</style></author><author><style face="normal" font="default" size="100%">Savira Ekawardhani</style></author><author><style face="normal" font="default" size="100%">Ramadani Eka Putra</style></author><author><style face="normal" font="default" size="100%">Dzul Ikram</style></author><author><style face="normal" font="default" size="100%">Muhammad Faruk</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Ethanolic Extract of Propolis from Tetragonula laeviceps: Selective  Cytotoxicity for MCF-7 Breast Cancer cells</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Breast cancer</style></keyword><keyword><style  face="normal" font="default" size="100%">MCF-7 Breast Cancer Cells</style></keyword><keyword><style  face="normal" font="default" size="100%">Proliferation</style></keyword><keyword><style  face="normal" font="default" size="100%">Propolis</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">1177-1180</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Many patients with breast cancer fail to respond to conventional chemotherapeutic agents; these agents are also associated with numerous adverse events and toxicities. These concerns have led to the ongoing search for natural ingredients with antitumor effects. As such, the aim of this study was to explore the anti-cancer properties of an ethanolic extract of propolis (EEP), a natural product derived from the stingless bee, from &lt;em&gt;Tetragonula laeviceps.&lt;/em&gt; &lt;strong&gt;Methods:&lt;/strong&gt; Bioactive components of EEP were identified by gas chromatography–mass spectrometry (GC–MS) and antioxidant capacity was tested by 2.2-diphenyl1-picrylhydrazyl (DPPH) analysis. Selective cytotoxic actions of EEP on both MCF-7 and Vero cells were then evaluated using the MTT assay. Polyphenols were identified as the major components of EEP from &lt;em&gt;T. laeviceps&lt;/em&gt;. &lt;strong&gt;Results:&lt;/strong&gt; our results indicated that EEP was selectively toxic for human MCF-7 breast cancer cells and had only limited impact on African Green Monkey kidney Vero cells. &lt;strong&gt;Conclusion: &lt;/strong&gt;EEP from T. laeviceps has bioactive components that may selectively inhibit the proliferation of cancer cells. As such, EEP may be useful source material to be used for the development of novel anti-cancer agents.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1177</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Rina Masadah&lt;sup&gt;1&lt;/sup&gt; , Savira Ekawardhani&lt;sup&gt;2&lt;/sup&gt; , Ramadani Eka Putra&lt;sup&gt;3&lt;/sup&gt; , Dzul Ikram&lt;sup&gt;1,4&lt;/sup&gt;, Muhammad Faruk&lt;sup&gt;5&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pathology Anatomy, Faculty of Medicine, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biomedical Science, Faculty of Medicine, Padjajaran University, Bandung, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;School of Life Sciences and Technology, Bandung Institute of Technology, Bandung, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Histology, Muslim University of Indonesia, Makassar, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Shahad Myasar Alfaris</style></author><author><style face="normal" font="default" size="100%">Rasha Khalid Dhahir</style></author><author><style face="normal" font="default" size="100%">Amina Mudhafar Al-Nima</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Preparation, Evaluation of Propolis Extract Gel and exploring its Antioxidant, Antimicrobial Activity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Carbopol-934</style></keyword><keyword><style  face="normal" font="default" size="100%">Poloxamer-407</style></keyword><keyword><style  face="normal" font="default" size="100%">Propolis</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">675-681</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Propolis is a wax-like resin which is produced by different types of bees by mixing resinous secretions of plants with beeswax and other products of bees' metabolism. However, this natural product contains a group of compounds that are responsible for various propolis activities including antimicrobial, anticancer, antioxidant, antiviral, and others. This study aims to prepare different gel formulae that contain various concentrations of propolis extract using two different polymers and to evaluate their physical properties, antioxidant, and antimicrobial activities. &lt;strong&gt;Method: &lt;/strong&gt;Propolis was extracted depending on the hydroalcoholic method; six different gel formulae (P-1 to P-6) were prepared with different concentrations of propolis extract (0.5, 1, and 1.5%) using two different polymers; carbopol-934 and poloxamer-407, in concentrations of 0.5 and 25% respectively. The formulae were evaluated physically for their visual appearance, pH, viscosity, spreadability, and physiological compatibility with the skin. The anti-microbial activities were investigated by well diffusion method against various bacterial species including &lt;em&gt;Staphylococcus aureus&lt;/em&gt; (gram+), Pseudomonas aeruginosa (gram-), Enterococcus fecalis (gram+) and against one fungal species which is Candida albicans. Also, the antioxidant activity was determined utilizing 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assay. Finally, a stability test was carried out for the chosen formula.&lt;strong&gt; Results:&lt;/strong&gt; The six formulae (P-1 to P-6) were successfully prepared and evaluated and they were acceptable in their physical appearance and consistency, pH reading was in the range of 5.33±0.08 to 5.72±0.02 (p&amp;gt;0.05), a study of the skin irritation revealed no undesirable side effect, while the viscosity was in the range of 128.99±0.07 to 248.54±1.04 Pa.s (p&amp;gt;0.05), also the carbopol-934 containing formulae revealed good spreadability (1.495±0.075 to 5.15±0.35 mg.cm/s, p&amp;gt;0.05), in comparison to poloxamer-407 containing ones. Both carbopol-934 and poloxamer-407 containing formulae exhibited antimicrobial activity but the P-3 formula had the largest inhibition zone against &lt;em&gt;C. Albicans &lt;/em&gt;(16.1mm), and only P-2, P-5 and P-6 were active against &lt;em&gt;pseudomonas aeruginosa&lt;/em&gt; (12mm in all), while P-2 had the largest inhibition zone against&lt;em&gt; enterococcus fecalis&lt;/em&gt; (13.2 mm), P-2 and P-5 showed the largest activity against &lt;em&gt;staphylococcus aureus&lt;/em&gt; (15.5 and 14.6 mm respectively). The carbopol-934-containing formulae exhibited higher antioxidant activity than those with poloxamer-407, and the best-calculated IC50 belonged to P-2 (1.19 mg/ml). &lt;strong&gt;Conclusion:&lt;/strong&gt; All the prepared formulae showed antimicrobial and antioxidant activities with some controversial results. However, P-2 (1% propolis extract and 0.5% carbopol-934), was active against all types of the tested microorganism, and had the best-calculated IC50, in addition to that it was a stable formula.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">675</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Shahad Myasar Alfaris*, Rasha Khalid Dhahir, Amina Mudhafar Al-Nima&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Pharmaceutics, College of Pharmacy, University of Mosul, Mosul, IRAQ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Al Mukhlas Fikri</style></author><author><style face="normal" font="default" size="100%">Ahmad Sulaeman</style></author><author><style face="normal" font="default" size="100%">Sri Anna Marliyati</style></author><author><style face="normal" font="default" size="100%">Mokhamad Fahrudin</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antiemetic Activity of Trigona spp. Propolis from Three Provinces of Indonesia with Two Methods of Extraction</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antiemetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Propolis</style></keyword><keyword><style  face="normal" font="default" size="100%">Retching</style></keyword><keyword><style  face="normal" font="default" size="100%">Stingless bee</style></keyword><keyword><style  face="normal" font="default" size="100%">Trigona spp</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/407</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">120-122</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Propolis is a resinous substance collected by bees to protect their hives. One of the least explored function of propolis is its antiemetic activity. The present study aimed to investigate the antiemetic activity of &lt;em&gt;Trigona &lt;/em&gt;spp. propolis from three provinces of Indonesia. &lt;strong&gt;Methods:&lt;/strong&gt; Ultrasound-assisted extraction using two kinds of solvent, water and ethanol was conducted to extract propolis from South Sulawesi, South Kalimantan and Banten. Antiemetic activity was observed on copper sulfate&amp;ndash;induced emesis in young chicks. &lt;strong&gt;Result:&lt;/strong&gt; All propolis indicated antiemetic activity, in which water extract had higher activity than ethanol extract. Regardless the type of solvents, propolis from South Sulawesi showed higher antiemetic activity than others. &lt;strong&gt;Conclusion:&lt;/strong&gt; This study demonstrated that propolis has antiemetic activity, in which propolis from South Sulawesi showed the highest activity and water extraction is recommended.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">120</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Al Mukhlas Fikri&lt;sup&gt;1&lt;/sup&gt;, Ahmad Sulaeman&lt;sup&gt;1&lt;/sup&gt;*, Sri Anna Marliyati&lt;sup&gt;1&lt;/sup&gt;, Mokhamad Fahrudin&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Community Nutrition, Faculty of Human Ecology, Bogor Agricultural University, Bogor 16680, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Veterinary Medicine, Bogor Agricultural University, Bogor 16680, INDONESIA.&lt;/p&gt;</style></auth-address></record></records></xml>