<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Habib Ganfon</style></author><author><style face="normal" font="default" size="100%">Axel Ahouansou</style></author><author><style face="normal" font="default" size="100%">Celia Dechavanne</style></author><author><style face="normal" font="default" size="100%">Callinice Capo-Chichi</style></author><author><style face="normal" font="default" size="100%">Latifou Lagnika</style></author><author><style face="normal" font="default" size="100%">Agnes Aubouy</style></author><author><style face="normal" font="default" size="100%">Sebastien Dechavanne</style></author><author><style face="normal" font="default" size="100%">Achille Massougbodji</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Cytotoxic Activity of Annona Muricata L, Momordica Charantia L. and Launaea Taraxacifolia Willd. from Benin: A Flow Cytometric Approach</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Benin</style></keyword><keyword><style  face="normal" font="default" size="100%">Cancer</style></keyword><keyword><style  face="normal" font="default" size="100%">Cytotoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant extracts</style></keyword><keyword><style  face="normal" font="default" size="100%">selectivity</style></keyword><keyword><style  face="normal" font="default" size="100%">THP-1 cells</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">727-732</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Cancer is rising worldwide, causing approximately 9.7 million deaths in 2022. Treatments are costly, have significant side effects, and are sometimes unavailable in Benin. Medicinal plants offer promising avenues for new therapeutic agents. &lt;strong&gt;Objective: &lt;/strong&gt;This study uses flow cytometry method to evaluate the cytotoxic activity of &lt;em&gt;Annona muricata&lt;/em&gt; (Annonaceae), &lt;em&gt;Momordica charantia&lt;/em&gt; (Cucurbitaceae) and &lt;em&gt;Launaea taraxacifolia&lt;/em&gt; (Asteraceae), three plants from the Beninese pharmacopoeia known for their anti-cancer properties. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; The leaves of A. muricata, &lt;em&gt;L. taraxacifolia &lt;/em&gt;and whole plants of &lt;em&gt;M. charantia&lt;/em&gt; were collected in southern Benin. Extracts were prepared by aqueous decoction and sequential extraction with solvents of increasing polarity (dichloromethane, ethyl acetate, methanol). The phytochemical profiles of the extracts were determined using TLC and tube tests. The cytotoxicity of the extracts was evaluated on THP-1 cancer cells and PBMC healthy cells. After treatment with the extracts, cell viability was measured by flow cytometry after staining with Thiazole Orange and Hoechst 33258. &lt;strong&gt;Results:&lt;/strong&gt; The dichloromethane extracts of &lt;em&gt;A. muricata&lt;/em&gt; and &lt;em&gt;M. charantia&lt;/em&gt;, and the ethyl acetate extract of &lt;em&gt;M. charantia&lt;/em&gt; and&lt;em&gt; L. taraxacifolia &lt;/em&gt;showed significant cytotoxic effects on THP-1 cells. Their half-maximal inhibitory concentrations (IC&lt;sub&gt;50&lt;/sub&gt;) were 139.6 μg/mL, 72.89 μg/mL, 81.88 μg/mL and 106.3 μg/ mL, respectively. These extracts also demonstrated good selectivity toward normal cells. Phytochemical screening revealed the presence of alkaloids, coumarins, flavonoids, anthracene glycosides and triterpenes in the active extracts. &lt;strong&gt;Conclusion:&lt;/strong&gt; This study demonstrated the cytotoxic potential of three medicinal plants from the Beninese pharmacopoeia which may serve to develop further new anticancer therapies.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">727</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Habib Ganfon&lt;sup&gt;1*&lt;/sup&gt;, Axel Ahouansou&lt;sup&gt;1,2,3,4&lt;/sup&gt;, Célia Dechavanne&lt;sup&gt;2,5&lt;/sup&gt;, Callinice Capo- Chichi&lt;sup&gt;3&lt;/sup&gt;, Latifou Lagnika&lt;sup&gt;4&lt;/sup&gt;, Agnès Aubouy&lt;sup&gt;2,6&lt;/sup&gt;, Sébastien Dechavanne&lt;sup&gt;2,5&lt;/sup&gt;, Achille Massougbodji&lt;sup&gt;2&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Laboratoire de Pharmacognosie et Phytothérapie du Centre de Recherche et de Développement du Médicament (CRDM-PharmaLab), 01 BP 188, Université d’Abomey-Calavi (UAC), BENIN&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Institut de Recherche Clinique du Benin (IRCB), 04 BP 1114, Abomey-Calavi, BENIN&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Laboratoire de recherche sur les Biomarqueurs Moléculaires en Cancérologie et en Nutrition, Unité de Biochimie et Biologie Moléculaire UAC, BENIN&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Laboratoire de Biologie Intégrative pour l’Innovation Thérapeutique, Unité de Biochimie et des Substances Naturelles Bioactives, UAC, BENIN&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;IRD, Inserm, MERIT, Université Paris Cité, F-75006 Paris, FRANCE&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;UMR 152 PHARMADEV, IRD, Université de Toulouse, FRANCE&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Angel Armando Marin Raico</style></author><author><style face="normal" font="default" size="100%">Rosa Isabel Florez Carrasco</style></author><author><style face="normal" font="default" size="100%">Jesus Eduardo Rojas Jaimes</style></author><author><style face="normal" font="default" size="100%">Juana Elvira Chavez Flores</style></author><author><style face="normal" font="default" size="100%">Jose Arenas Gamio</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of the Ethanolic Extract of Chuquiraga weberbaueri Tovar on Glycemia in BALB/c Mice</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Hypoglycemic Agents</style></keyword><keyword><style  face="normal" font="default" size="100%">Mice</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant extracts</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">63-70</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Diabetes mellitus is one of the most prevalent diseases worldwide and is associated with many complications. While there are many drugs available to control blood glucose levels, many people cannot access them due to economic reasons. &lt;strong&gt;Object: &lt;/strong&gt;The aim of this study was to determine the hypoglycemic effect of the ethanolic extract of &lt;em&gt;Chuquiraga weberbaueri&lt;/em&gt; in mice induced with hyperglycemia. &lt;strong&gt;Methods: &lt;/strong&gt;The mice were divided into 6 groups: the first group served as a control group and was administered only physiological saline solution; the second group was induced to hyperglycemia with Alloxan. The following three groups were induced with Alloxan and additionally administered ethanolic extract of &lt;em&gt;Chuquiraga weberbaueri&lt;/em&gt; at different concentrations of 100 mg/kg, 250 mg/kg, and 500 mg/kg respectively. The last group was administered Alloxan and glibenclamide. The glucose levels were measured for each group at 2, 4, and 24 hours after administering the extracts. &lt;strong&gt;Results: &lt;/strong&gt;The phytochemical analysis of the ethanolic extracts of the leaves of &lt;em&gt;Chuquiraga weberbaueri&lt;/em&gt; showed the presence of flavonoids, tannins, alkaloids and steroids. The ethanolic extracts (100 mg/kg at 2 hours and 250 mg/kg at 2 and 4 hours) demonstrated a decrease in blood glucose compared to the control group. In the toxicity test, the comparison between the control group and the “extract” treatment group showed that no conclusive results were observed with respect to the chuquiragua extract. &lt;strong&gt;Interpretation:&lt;/strong&gt; The results of the study showed that the ethanolic extract of &lt;em&gt;Chuquiraga weberbaueri &lt;/em&gt;showed the effect of reducing blood glucose in BALB/c mice.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">63</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Angel Armando Marin Raico&lt;sup&gt;1&lt;/sup&gt;, Rosa Isabel Florez Carrasco&lt;sup&gt;1&lt;/sup&gt;, Jesús Eduardo Rojas Jaimes&lt;sup&gt;1,2&lt;/sup&gt;, Juana Elvira Chávez Flores&lt;sup&gt;3&lt;/sup&gt;, José Arenas Gamio&lt;sup&gt;4&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Escuela de Medicina Humana, Universidad Científica del Sur, Lima-PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Facultad de Ciencias de la Salud, Universidad Privada del Norte, Lima-PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Escuela de Farmacia y Bioquímica, Universidad Norbert Wiener, Lima-PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Departamento de Patología Clínica, Hospital Guillermo Almenara Irigoyen, Lima-PERÚ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Inbaraj Susai Domnic</style></author><author><style face="normal" font="default" size="100%">Prasanna Mohanabhaskaran</style></author><author><style face="normal" font="default" size="100%">Imran Zaheer</style></author><author><style face="normal" font="default" size="100%">Semmal Syed Meerasa</style></author><author><style face="normal" font="default" size="100%">Ramaprabha Prabhakar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Evaluation of Potential Toxicity Associated with Antidiabetic Herbs in Saudi Arabia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antidiabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetes</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbal medicines</style></keyword><keyword><style  face="normal" font="default" size="100%">KSA</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal herbs</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytotherapy</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant extracts</style></keyword><keyword><style  face="normal" font="default" size="100%">Saudi Arabia</style></keyword><keyword><style  face="normal" font="default" size="100%">Toxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Traditional</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">576-581</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Diabetes mellitus is a serious, long-lasting disease that is characterized by high blood sugar levels, leading to more severe complications involving other organ systems of the body. Diabetes is becoming more common worldwide. Managing diabetes can be complicated, but many people, especially in Saudi Arabia, often use traditional herbal medicines to treat the condition. Our study concentrates on assessing the safety of commonly used antidiabetic herbs in Saudi Arabia by examining their potential toxicity. &lt;strong&gt;Method:&lt;/strong&gt; Using keywords and their variations, we conducted a systematic search of the PubMed and Google Scholar databases to find studies on treatments based on antidiabetic herbs and their toxic effects from 2014 to 2024. &lt;strong&gt;Result:&lt;/strong&gt; Our study revealed that the use of medicinal plants for treating and managing diabetes along with its complications is becoming popular around the globe. These medicinal plants are also being used as primary sources of developing modern pharmaceutical antidiabetic drugs. Phytotherapy is safe to treat diabetes as herbal bioactive components act through many biological pathways. They may inhibit α-glucosidase enzyme, enhance GLUT-4 translocation, and also improve lipid profile.&lt;strong&gt; Conclusion:&lt;/strong&gt; The use of natural plants having medicinal properties is popular for the treatment of diabetes. Claims of their usefulness by traditional healers are being supported by scientific evidence also. To determine the right dosage of these medicinal herbs, cytotoxicity tests or short-term experiments are done to establish doses of plants used in vitro and in vivo. Toxicity concerns are a primary reason why healthcare professionals hesitate to incorporate herbal products into the healthcare system. That’s why it is necessary to screen such plants for their toxicity to differentiate pharmacological efficacy from adverse effects.&amp;nbsp;&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">576</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Inbaraj Susai Domnic*, Prasanna Mohanabhaskaran, Imran Zaheer, Semmal Syed Meerasa, Ramaprabha Prabhakar&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;Department of Basic Medical Sciences, College of Medicine- Dawadmi and Shaqra, Shaqra University, SAUDI ARABIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mruthunjaya Kenganora</style></author><author><style face="normal" font="default" size="100%">Sushma Rudraswamy</style></author><author><style face="normal" font="default" size="100%">Jai Shankar Puttabuddi Hombarvalli</style></author><author><style face="normal" font="default" size="100%">Nagabhushana Doggalli</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Phytochemicals  A Novel Therapeutic Approach to Control Oral Biofilm</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Dental plaque</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal herbs</style></keyword><keyword><style  face="normal" font="default" size="100%">Microbial resistance</style></keyword><keyword><style  face="normal" font="default" size="100%">Oral biofilm</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemicals</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant extracts</style></keyword><keyword><style  face="normal" font="default" size="100%">Quorum sensing</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">730-736</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Humans and micro-organisms have co-evolved having a synergetic relationship with their resident microbiome. The mouth features a diverse microbiota that grows on oral surfaces as functionally and structurally organized biofilms. The oral biofilms are accountable for causing a wide range of chronic diseases and owing to the development of antibiotic-resistant bacteria it has really become tough to treat with efficacy. Operative control of oral biofilm and the resulting infectious diseases epitomizes a significant universal challenge. For this kind of therapeutics, natural herbal products are perfect candidates because of their unique properties. The current review presents a novel approach to control and eradicate oral biofilm by the phytochemicals. Research on phytochemicals is zealously focused on health promotion, disease prevention, and also on the development of novel therapeutic interventions.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">730</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Mruthunjaya Kenganora&lt;sup&gt;1&lt;/sup&gt;, Sushma Rudraswamy&lt;sup&gt;2,&lt;/sup&gt;*, Jai Shankar Puttabuddi Hombarvalli&lt;sup&gt;3&lt;/sup&gt;, Nagabhushana Doggalli&lt;sup&gt;4&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacognosy, J.S.S College of Pharmacy, Mysore, J.S.S Academy of Higher Education and Research, Mysore, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Public Health Dentistry, J.S.S Dental College and Hospital, J.S.S Academy of Higher Education and Research, Mysore, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Oral Medicine and Radiology, J.S.S Dental College and Hospital, J.S.S Academy of Higher Education and Research, Mysore, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Oral Medicine and Radiology, J.S.S Dental College and Hospital, J.S.S Academy of Higher Education and Research, Mysore, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Nkiru Nwamaka Ezeani</style></author><author><style face="normal" font="default" size="100%">Udu Ama Ibiam</style></author><author><style face="normal" font="default" size="100%">Obasi Uche Orji</style></author><author><style face="normal" font="default" size="100%">Ikechuku Okorie Igwenyi</style></author><author><style face="normal" font="default" size="100%">Chinyere Aloke</style></author><author><style face="normal" font="default" size="100%">Esther Alum</style></author><author><style face="normal" font="default" size="100%">Partrick Mmaduabuchi Aja</style></author><author><style face="normal" font="default" size="100%">Okechukwu Paul Chima Ugwu</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effects of Aqueous and Ethanol Root Extracts of Olax subscopioidea on Inflammatory Parameters in Complete Freund’s Adjuvant-Collagen Type II Induced Arthritic Albino Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adjuvant</style></keyword><keyword><style  face="normal" font="default" size="100%">Arthritis</style></keyword><keyword><style  face="normal" font="default" size="100%">Indomethacine</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant extracts</style></keyword><keyword><style  face="normal" font="default" size="100%">Rats</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">16-25</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Aim/Background:&lt;/strong&gt; Rural and Urban dwellers in Nigeria claim to treat their arthritis with &lt;em&gt;Olax subscorpioidea&lt;/em&gt; root extracts. One of the reasons they chose this treatment is that it is effective and cost less than orthodox drugs with their accompanying side effects. Hence the aim of this study is to investigate the anti-arthritis effects of &lt;em&gt;Olax subscorpioidea &lt;/em&gt;Afzel ethanol and aqueous root extracts on chicken type II-Complete Freund’s adjuvant (CFA) induced arthritis rat model. &lt;strong&gt;Materials and Method:&lt;/strong&gt; The anti-arthritic potential of ethanol and aqueous root extracts of &lt;em&gt;Olax subscorpioidea&lt;/em&gt; was evaluated using the chicken type II-Complete Freund’s adjuvant model in 135 female wistar albino rats. The rats were treated with aqueous and ethanol root extracts of &lt;em&gt;Olax subscorpioidea&lt;/em&gt; at varying doses and standard indomethacine drug. &lt;strong&gt;Results:&lt;/strong&gt; The ethanol and aqueous root extracts of &lt;em&gt;Olax subscorpioidea &lt;/em&gt;showed significant anti-arthritic activity that was statistically similar to that of indomethacine. Our results suggest that the alcoholic extract of &lt;em&gt;Olax subscorpioidea &lt;/em&gt;showed significant (&lt;em&gt;P&lt;/em&gt;&amp;lt;0.05) anti-arthritic potential.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">16</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Nkiru Nwamaka Ezeani&lt;sup&gt;*&lt;/sup&gt;, Udu Ama Ibiam, Obasi Uche Orji, Ikechuku Okorie Igwenyi, Chinyere Aloke, Esther Alum, Partrick Mmaduabuchi Aja, Okechukwu Paul Chima Ugwu &lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;Department of Biochemistry, Ebonyi State University, Abakaliki, NIGERIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Jasmin T Tutor</style></author><author><style face="normal" font="default" size="100%">Christine L Chichioco-Hernandez</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Angiotensin-Converting Enzyme Inhibition of Fractions from Eleusine indica Leaf Extracts</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bioactive extracts</style></keyword><keyword><style  face="normal" font="default" size="100%">High-blood pressure</style></keyword><keyword><style  face="normal" font="default" size="100%">Hypertension</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant extracts</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/360</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">25-28</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;Solvent fractions and decoction of &lt;em&gt;Eleusine indica&lt;/em&gt; leaves were tested for their ability to inhibit angiotensin-converting enzyme (ACE), an important component of the Renin-Angiotensin- Aldosterone System which is a critical regulator of arterial blood pressure. The ACE inhibitory activity of each fraction was measured by employing a colorimetric assay based on the hydrolysis of histidyl-hippuryl-leucine (HHL) by ACE. Preliminary assay results revealed that the ethyl acetate fraction exhibited the highest antihypertensive activity with a percent inhibition of 51.51%. This fraction was considered for further isolation using a bioassay-guided fractionation scheme.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">25</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Jasmin T Tutor, Christine L Chichioco-Hernandez* &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Institute of Chemistry, University of the Philippines,&amp;nbsp;Diliman, Quezon City-1101, PHILIPPINES&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Noemi D. Paguigan,</style></author><author><style face="normal" font="default" size="100%">Christine L. Chichioco-Hernandez,</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">15-Lipoxygenase inhibition of selected Philippine medicinal plants</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Asthma</style></keyword><keyword><style  face="normal" font="default" size="100%">Inflammation</style></keyword><keyword><style  face="normal" font="default" size="100%">Lipoxygenase</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plants</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant extracts</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">18th Feb,2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">43-46</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;Several extracts from Philippine medicinal plants used for asthma and other inflammatory diseases were evaluated for their ability to inhibit the action of 15-lipoxygenase. The inhibitory activity was tested spectrophotometrically using quercetin as positive control. Eleven species belonging to 11 families displayed varying inhibitory activities. &lt;em&gt;Commelina diffusa&lt;/em&gt; and &lt;em&gt;Euphorbia hirta&lt;/em&gt; showed the highest inhibitory activity at 51.3% and 48.5%, respectively. These plants may contain new 15-lipoxygenase inhibitors.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Key words: &lt;/strong&gt;Asthma, inflammation, lipoxygenase, medicinal plants, plant extra.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Noemi D. Paguigan&lt;sup&gt;1&lt;/sup&gt; and Christine L. Chichioco-Hernandez&lt;sup&gt;*,2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Natural Sciences Research Institute, University of the Philippines, Diliman, Quezon City, Philippines 1101&lt;sup&gt;&lt;/sup&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Institute of Chemistry, College of Science, University of the Philippines, Diliman, Quezon City, Philippines 1101&lt;/p&gt;</style></auth-address></record></records></xml>