<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Twinkle Francis</style></author><author><style face="normal" font="default" size="100%">S Rajeshkumar</style></author><author><style face="normal" font="default" size="100%">Anita Roy</style></author><author><style face="normal" font="default" size="100%">T Lakshmi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anti-inflammatory and Cytotoxic Effect of Arrow Root Mediated Selenium Nanoparticles</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-inflammatory</style></keyword><keyword><style  face="normal" font="default" size="100%">Brine shrimp</style></keyword><keyword><style  face="normal" font="default" size="100%">Green synthesis</style></keyword><keyword><style  face="normal" font="default" size="100%">Selenium nanoparticles</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1363-1367</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Nanoparticles serve to reduce toxicity, enhance bioactivity and improve targeting. Selenium nanoparticles (SeNPs) are explored because of it’s unique characteristics and various known therapeutic benefits such as antioxidants activities and reducing risk of cancer. In this study, arrow root which is a starch obtained from tapioca or cassava is mediated with SeNPs and studied for it’s anti-inflammatory and cytotoxic effect. The plant extract of arrow root was prepared and mixed with the sodium selenite solution. The solution is kept in a magnetic stirrer while being observed for any colour change. The synthesis of nanoparticles is observed using UV-vis spectrophotometry. Then the anti-inflammatory activity is observed using albumin denaturation assay and cytotoxic analysis conducted on brine shrimp nauplii. The results showed that there was a lower toxicity rate of SeNPs and significant anti-inflammatory activity which concludes that these nanoparticles can be used in various drug designing aspects in future.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1363</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Twinkle Francis, S Rajeshkumar*, Anita Roy, T Lakshmi &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Nanobiomedicine Lab, Department of Pharmacology, Saveetha Dental College and Hospital, SIMATS, Chennai – 600077, TN, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">S Maposa</style></author><author><style face="normal" font="default" size="100%">AJ Afolayan</style></author><author><style face="normal" font="default" size="100%">GA Otunola</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Toxicity Assessment of Vachellia karro (Hayne) Banfi and Galasso Pods using Brine Shrimp Assay</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Brine shrimp</style></keyword><keyword><style  face="normal" font="default" size="100%">Cyst</style></keyword><keyword><style  face="normal" font="default" size="100%">Lethality</style></keyword><keyword><style  face="normal" font="default" size="100%">Nauplii</style></keyword><keyword><style  face="normal" font="default" size="100%">Toxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Vachellia karroo</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February  2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1-5</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background and Objective:&lt;em&gt; &lt;/em&gt;&lt;/strong&gt;&lt;em&gt;Vachellia karroo &lt;/em&gt;is widely used in folk medicine in the Eastern Cape Province South Africa, however, the pods are usually discarded as waste. This study evaluated the toxicity of acetone, hexane, aqueous and methanol extracts of &lt;em&gt;Vachellia karroo &lt;/em&gt;pods using brine shrimp model. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Different concentrations (0.0625-1 mg/mL) of the extracts were used to incubate the cysts and nauplii of brine shrimp (&lt;em&gt;Artemia salina&lt;/em&gt;) to evaluate their effects on the hatching of the cyst and mortality of the nauplii respectively. The percentage of hatched cysts and Lethal Concentration (LC&lt;sub&gt;50&lt;/sub&gt;) needed to kill 50% of the nauplii were recorded. &lt;strong&gt;Results: &lt;/strong&gt;Successful hatching of the cysts was in order: Aqueous extract&amp;gt; methanol extract&amp;gt; hexane extract&amp;gt; acetone extract. The hatching of nauplii was in a concentration dependent fashion, with hatching success decreasing with increase in concentration of extracts. &lt;strong&gt;Conclusion: &lt;/strong&gt;Lethality of extracts determined based on Meyers’ index of toxicity, revealed that acetone and hexane extracts of &lt;em&gt;V. karroo &lt;/em&gt;were moderately toxic.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;S Maposa, AJ Afolayan, GA Otunola* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Medicinal Plants and Economic Development (MPED) Research Centre, Department of Botany, University of Fort Hare, Alice 5700, SOUTH AFRICA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rukhsana Abdul Rub</style></author><author><style face="normal" font="default" size="100%">Manohar Janardhan Patil</style></author><author><style face="normal" font="default" size="100%">Areej Abdul Siddiqui</style></author><author><style face="normal" font="default" size="100%">Priyanka Rambhau Ghorpade</style></author><author><style face="normal" font="default" size="100%">Alpana Subhod Moghe</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Free Radical Scavenging and Cytotoxic Potential of Celosia argentea</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Brine shrimp</style></keyword><keyword><style  face="normal" font="default" size="100%">Mitotic index</style></keyword><keyword><style  face="normal" font="default" size="100%">MTT</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenolics.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">09th Mar, 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">191-197</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Oxidative stress due to reactive oxygen species often leads to pathogenesis of chronic diseases such as cancer. Research states that a diet rich in polyphenols renders many health benefits by scavenging such harmful reactive species. &lt;em&gt;Celosia argentea&lt;/em&gt; (Amaranthaceae), a common weed in India has been reported as a potential source of cheap, natural antioxidants due to its phenolic abundance. In this research work efforts were made to identify and screen the phenolic rich fractions of &lt;em&gt;Celosia argentea&lt;/em&gt; for their antioxidant and anticancer potential. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;Various solvent fractions with increasing polarity were subjected to total phenolic content, followed by antioxidant assays- DPPH, ABTS and anti proliferative assays- Brine shrimp Bioassay, Antimitotic and MTT assays. &lt;strong&gt;Results:&lt;/strong&gt; IC&lt;sub&gt;50&lt;/sub&gt; value of methanolic fraction for DPPH assay was statistically significant (26.25; ***P&amp;lt;0.001) when compared with ascorbic acid (12.50; ***P&amp;lt;0.001). Also TEAC values for methanolic fraction and BHT (standard) for ABTS assay were similar (2.1; ***P&amp;lt;0.001) Methanolicfraction at 400 &amp;mu;g/ml exhibited strong cytotoxicity (9.0 &amp;plusmn; 0.81; ***P&amp;lt;0.001) against brine shrimps comparable to Methotrexate at 50 &amp;mu;g/ml(10; ***P&amp;lt;0.001) and significantly reduced mitotic index from 96.8 to 38.0 (***P&amp;lt;0.001) which was further confirmed by MTT assay where IC&lt;sub&gt;50&lt;/sub&gt; value of methanolic fraction for SiHa and MCF-7 cells was found to be 28 &amp;mu;g/ml with no cytotoxicity to normal cells proving its anticancer potential. &lt;strong&gt;Conclusion: &lt;/strong&gt;This research proves antioxidant and anticancer potential of phenolic rich fraction of Celosia argentea and suggests it to be useful in cancer management as antifroliferative, chemo preventive and in cancer chemotherapy induced immune suppression and oxidative stress.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words:&lt;/strong&gt; Antioxidant, Brine shrimp, Mitotic index, MTT, Phenolics.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">191</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Rukhsana Abdul Rub&lt;sup&gt;*1&lt;/sup&gt;, Manohar Janardhan Patil&lt;sup&gt;2&lt;/sup&gt;, Areej Abdul Siddiqui&lt;sup&gt;1&lt;/sup&gt;, Priyanka Rambhau Ghorpade&lt;sup&gt;1&lt;/sup&gt;, and Alpana Subhod Moghe&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1,*&lt;/sup&gt;Department of Pharmacognosy, M.C.E. Society&amp;rsquo;s Allana College of Pharmacy, Camp, Pune-411001, Maharashtra, India&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Molecular and Cell Biology, MMM&amp;rsquo;s College of Pharmacy, Kalewadi, Pimpri, Pune, Maharashtra, India&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Molecular and Cell Biology, Rajiv Gandhi Institute of Biotechnology, Bharati Vidyapeeth University, Pune, Maharashtra, India&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rukhsana Abdul Rub</style></author><author><style face="normal" font="default" size="100%">Manohar Janardhan Patil</style></author><author><style face="normal" font="default" size="100%">Areej Abdul Siddiqui</style></author><author><style face="normal" font="default" size="100%">Priyanka Rambhau Ghorpade</style></author><author><style face="normal" font="default" size="100%">Alpana Subhod Moghe</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Free Radical Scavenging and Cytotoxic Potential of Celosia argentea</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Brine shrimp</style></keyword><keyword><style  face="normal" font="default" size="100%">Mitotic index</style></keyword><keyword><style  face="normal" font="default" size="100%">MTT</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenolics.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">01/2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">191-197</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Oxidative stress due to reactive oxygen species often leads to pathogenesis of chronic diseases such as cancer. Research states that a diet rich in polyphenols renders many health benefits by scavenging such harmful reactive species. &lt;em&gt;Celosia argentea&lt;/em&gt; (Amaranthaceae), a common weed in India has been reported as a potential source of cheap, natural antioxidants due to its phenolic abundance. In this research work efforts were made to identify and screen the phenolic rich fractions of &lt;em&gt;Celosia argentea&lt;/em&gt; for their antioxidant and anticancer potential. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Various solvent fractions with increasing polarity were subjected to total phenolic content, followed by antioxidant assays-DPPH, ABTS and anti proliferative assays- Brine shrimp Bioassay, Antimitotic and MTT assays. &lt;strong&gt;Results:&lt;/strong&gt; IC&lt;sub&gt;50&lt;/sub&gt; value of methanolic fraction for DPPH assay was statistically significant (26.25; &lt;sup&gt;***&lt;/sup&gt;P&amp;lt;0.001) when compared with ascorbic acid (12.50; &lt;sup&gt;***&lt;/sup&gt;P&amp;lt;0.001). Also TEAC values for methanolic fraction and BHT (standard) for ABTS assay were similar (2.1; &lt;sup&gt;***&lt;/sup&gt;P&amp;lt;0.001) Methanolicfraction at 400 &amp;mu;g/ml exhibited strong cytotoxicity (9.0 &amp;plusmn; 0.81; &lt;sup&gt;***&lt;/sup&gt;P&amp;lt;0.001) against brine shrimps comparable to Methotrexate at 50 &amp;mu;g/ml(10; &lt;sup&gt;***&lt;/sup&gt;P&amp;lt;0.001) and significantly reduced mitotic index from 96.8 to 38.0 (&lt;sup&gt;***&lt;/sup&gt;P&amp;lt;0.001) which was further confirmed by MTT assay where IC&lt;sub&gt;50&lt;/sub&gt; value of methanolic fraction for SiHa and MCF-7 cells was found to be 28 &amp;mu;g/ml with no cytotoxicity to normal cells proving its anticancer potential. &lt;strong&gt;Conclusion:&lt;/strong&gt; This research proves antioxidant and anticancer potential of phenolic rich fraction of Celosia argentea and suggests it to be useful in cancer management as antifroliferative, chemo preventive and in cancer chemotherapy induced immune suppression and oxidative stress.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">191</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Rukhsana Abdul Rub&lt;sup&gt;*1&lt;/sup&gt;, Manohar Janardhan Patil&lt;sup&gt;2&lt;/sup&gt;, Areej Abdul Siddiqui&lt;sup&gt;1&lt;/sup&gt;, Priyanka Rambhau Ghorpade&lt;sup&gt;1&lt;/sup&gt;, and Alpana Subhod Moghe&lt;sup&gt;3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1,*&lt;/sup&gt;Department of Pharmacognosy, M.C.E. Society&amp;rsquo;s Allana College of Pharmacy, Camp, Pune-411001,&amp;nbsp;&amp;nbsp;&amp;nbsp; Maharashtra, India.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Molecular and Cell Biology, MMM&amp;rsquo;s College of Pharmacy, Kalewadi, Pimpri, Pune, Maharashtra, India.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Molecular and Cell Biology, Rajiv Gandhi Institute of Biotechnology, Bharati Vidyapeeth University, Pune, Maharashtra, India.&lt;/p&gt;
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