<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Herra Williany Monalissa</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Nuraini Puspitasari</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">HMG-CoA Reductase Inhibitory Activity of Garcinia latissima Miq. Mesocarp Water Extract for Herbal Tea</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti Cholesterol</style></keyword><keyword><style  face="normal" font="default" size="100%">Garcinia Latissima</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbal Tea</style></keyword><keyword><style  face="normal" font="default" size="100%">HMG-CoA reductase</style></keyword><keyword><style  face="normal" font="default" size="100%">Mesocarp</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">s141-s146</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Context:&lt;/strong&gt; High cholesterol in the blood is a risk factor for atherosclerosis that causes various diseases. The main pharmacologic intervention to reduce cholesterol levels is inhibiting the HMG-CoA reductase enzyme. One of the genera of Garcinia, &lt;em&gt;Garcinia dulcis&lt;/em&gt;, has potential as an anti-cholesterol. Based on chemotaxonomy, &lt;em&gt;Garcinia latissima&lt;/em&gt; Miq. is also estimated to have a potency as anti-cholesterol.&lt;strong&gt; Aims:&lt;/strong&gt; This study aims to test the inhibition of HMG-CoA reductase water extract activity of&lt;em&gt; G. latissima&lt;/em&gt; fruit flesh with different duration of infusions.&lt;strong&gt; Materials and Methods:&lt;/strong&gt; &lt;em&gt;Garcinia latissima&lt;/em&gt; Miq. mesocarp was extracted using infusion method with different duration of infusions. Each of extracts was tested the inhibitory activity of HMG-CoA reductase as well as the determination of total flavonoid and total phenol content. In addition, the simplicia of the mesocarp of G.latissima Miq. will be made as a herbal tea and a hedonic test is performed to find out the degree of liking for the tea. &lt;strong&gt;Result:&lt;/strong&gt; The test results showed the inhibitory activity of 100 ppm &lt;em&gt;G. latissima&lt;/em&gt; Miq. mesocarp water extract with infusion for 5, 10 and 15 min respectively 11.32; 29.02; 13.03%. The 10 min extract with the largest enzyme inhibition had total flavonoids content of 31.24 mg QE / gram extract and total phenol content of 4.64 mg GAE/ gram extract. The result of the hedonic test for the colour, aroma, flavour of herbal tea formula A respectively 30; 30; 20% and formula B respectively for 40; 33.3; 50%. Conclusion: The water extract of G.latissima Miq mesocarp has a low potency in HMG-CoA reductase inhibitory activities.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">s141</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Herra Williany Monalissa, Berna Elya&lt;sup&gt;*&lt;/sup&gt;, Nuraini Puspitasari &lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Universitas Indonesia Depok, 16424, West Java, INDONESIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sarlina Jihan Lusiyanti</style></author><author><style face="normal" font="default" size="100%">Katrin</style></author><author><style face="normal" font="default" size="100%">Rissyelly</style></author><author><style face="normal" font="default" size="100%">Nuraini Puspitasari</style></author><author><style face="normal" font="default" size="100%">Putu Gita Maya Widyaswari Mahayasih</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">ACE Inhibitory Activity, Total Phenolic and Flavonoid Content of Pereskia saccharose Griseb. Leaves Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">ACE inhibitor</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoid</style></keyword><keyword><style  face="normal" font="default" size="100%">Pereskia saccharose Griseb</style></keyword><keyword><style  face="normal" font="default" size="100%">phenolic</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://phcogj.com/fulltext/316</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">285-287</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Angiotensin-converting enzyme inhibitors (ACEi) are drugs that can control hypertension. &lt;em&gt;Pereskia saccharose&lt;/em&gt; Griseb. leaves have been used traditionally as antihypertensive. &lt;strong&gt;Objective:&lt;/strong&gt; The objective of this study was to determine the antihypertensive activity through inhibition of ACE activity, the total phenolic content and total flavonoid content of the ethanolic extract of &lt;em&gt;Pereskia saccharose&lt;/em&gt; Griseb. leaves and its fractions. &lt;strong&gt;Methods:&lt;/strong&gt; Extraction was done by maceration with 80% ethanol and fractionation performed by liquid-liquid partition. &lt;strong&gt;Results:&lt;/strong&gt; &lt;em&gt;In vitro&lt;/em&gt; ACE inhibitory activity assay of the ethanolic extract using ACE Kit-WST Dojindo had IC&lt;sub&gt;50&lt;/sub&gt; value of 3.448 &amp;mu;g/mL and ethyl acetate fraction had IC&lt;sub&gt;50&lt;/sub&gt; value of 1.714 x 10-3 &amp;mu;g/mL. Ethyl acetate contained the highest amounts of both TPC (72.991 &amp;plusmn; 0.932 mg GAE/g sample) and TFC (61.337 &amp;plusmn; 1.612 mg QE/g sample). &lt;strong&gt;Conclusion:&lt;/strong&gt; The results suggest that &lt;em&gt;Pereskia saccharose&lt;/em&gt; Griseb. possess ACE inhibitory activity.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">285</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Sarlina Jihan Lusiyanti, Katrin, Rissyelly*, Nuraini Puspitasari &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmacognosy- Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Kampus Baru UI Depok 16424, Depok, INDONESIA.&amp;nbsp;&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Amanda Listiyani</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Nuraini Puspitasari</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant Activity and Lipoxygenase Enzyme Inhibitory Assay with Total Flavonoids Content from Garcinia hombroniana Pierre Stem Bark Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Garcinia hombroniana Pierre</style></keyword><keyword><style  face="normal" font="default" size="100%">Inflammation</style></keyword><keyword><style  face="normal" font="default" size="100%">Lipoxygenase</style></keyword><keyword><style  face="normal" font="default" size="100%">Total flavonoids content</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://phcogj.com/fulltext/314</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">276-279</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; &lt;em&gt;Garcinia&lt;/em&gt; has been known as a rich source of xanthones, flavonoids, and phenols. The aim of this research is to obtain data of antioxidant activity and to observe potential inhibition of lipoxygenase activity that most active from methanolic, ethyl acetate and n-hexane extracts with total flavonoids content from most active extracts from the bark of &lt;em&gt;Garcinia&lt;/em&gt; &lt;em&gt;hombroniana&lt;/em&gt; Pierre. &lt;strong&gt;Methods:&lt;/strong&gt; The antioxidant activity was measured using the ferric reducing antioxidant power (FRAP), the anti-inflammatory assay was measured using inhibition of lipoxygenase activity test, qualitative analysis of flavonoids using thin layer chromatography, and total flavonoids content was measured using AlCl&lt;sub&gt;3&lt;/sub&gt; colorimetric method. &lt;strong&gt;Results:&lt;/strong&gt; The results showed that the ethyl acetate extract from &lt;em&gt;G. hombroniana&lt;/em&gt; Pierre stem bark as the most active extract for antioxidant and lipoxygenase inhibition activity with EC&lt;sub&gt;50&lt;/sub&gt; and IC&lt;sub&gt;50&lt;/sub&gt; value consecutively 15.34 &amp;mu;g /ml; 0.26 &amp;mu;g /ml. Total flavonoids content of ethyl acetate is 7.430 mg QE/g extract. The results of this study showed bark extract &lt;em&gt;Garcinia&lt;/em&gt; &lt;em&gt;hombroniana&lt;/em&gt; Pierre has antioxidant activity and potent to inhibit lipoxygenase activity. &lt;strong&gt;Conclusion:&lt;/strong&gt; Based on the research for methanolic, ethyl acetate and n-hexane extract, it can be concluded that the ethyl acetate extract of &lt;em&gt;G. hombroniana&lt;/em&gt; Pierre as the most active extract for antioxidant and lipoxygenase inhibition activity.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">276</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Amanda Listiyani, Berna Elya*, Nuraini Puspitasari &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmacognosy- Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Kampus Baru UI Depok, 16424, Depok, INDONESIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Nur Laily Putri</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Nuraini Puspitasari</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant Activity and Lipoxygenase Inhibition Test with Total Flavonoid Content from Garcinia kydia Roxburgh Leaves Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoid content</style></keyword><keyword><style  face="normal" font="default" size="100%">FRAP</style></keyword><keyword><style  face="normal" font="default" size="100%">Garcinia kydia Roxburgh</style></keyword><keyword><style  face="normal" font="default" size="100%">Lipoxygenase</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://phcogj.com/fulltext/315</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">280-284</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Antioxidant is one of the therapeutic strategies to overcome oxidative stress and inhibit synthesis of inflammatory mediators through lipoxygenase pathway. Garcinia is the largest of Clusiaceae family which has been proven to provide antioxidant and anti-inflammatory activity. &lt;em&gt;Garcinia kydia&lt;/em&gt; Roxburgh is one of the plants of this genus which is known to have antioxidant activity but lipoxygenase inhibition activity from this plant was unknown. &lt;strong&gt;Methods:&lt;/strong&gt; This study aimed to test antioxidant activity of the methanol, ethyl acetate and n-hexane extract from &lt;em&gt;Garcinia kydia&lt;/em&gt; Roxburgh leaves by FRAP (Ferric Reducing Antioxidant Power) method, anti-inflammatory activity was tested by inhibiting lipoxygenase and total flavonoid content by colorimetric methods AlCl&lt;sub&gt;3&lt;/sub&gt;. &lt;strong&gt;Results:&lt;/strong&gt; The results showed an antioxidant activity of methanol extract, ethyl acetate and n-hexane leaves of &lt;em&gt;Garcinia kydia&lt;/em&gt; Roxburgh have EC&lt;sub&gt;50&lt;/sub&gt; value, respectively 18,448; 12,389 and 31,260 &amp;mu;g/mL, and the lipoxygenase inhibition activity have IC&lt;sub&gt;50&lt;/sub&gt; value, respectively 0,556; 0,212 and 3,575 &amp;mu;g/mL. Ethyl acetate extract of &lt;em&gt;Garcinia kydia&lt;/em&gt; Roxburgh leaves was the most active extract in this study which has total flavonoid content, 30,650 mgQE/ gram extract. &lt;strong&gt;Conclusion:&lt;/strong&gt; The conclusion, &lt;em&gt;Garcinia kydia&lt;/em&gt; Roxburgh has antioxidant and lipoxygenase inhibition activity, with ethyl acetate extract as the most active extract which contains total flavonoids.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">280</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Nur Laily Putri, Berna Elya*, Nuraini Puspitasari &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmacognosy- Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Kampus Baru UI Depok 16424, Depok, INDONESIA.&lt;/p&gt;</style></auth-address></record></records></xml>