<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sundarachary Nagarjunakonda</style></author><author><style face="normal" font="default" size="100%">Sridhar Amalakanti</style></author><author><style face="normal" font="default" size="100%">Sristi Ram Dhishana</style></author><author><style face="normal" font="default" size="100%">Maddi Ramaiah</style></author><author><style face="normal" font="default" size="100%">Lalitha Rajanala</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">GC-MS Analysis of Indrakeeladri Native Medicine used in the Treatment of Stroke</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Dodecanoic acid methyl ester</style></keyword><keyword><style  face="normal" font="default" size="100%">Methyl 10-methyl undecanoate</style></keyword><keyword><style  face="normal" font="default" size="100%">Methyl tetradecanoate</style></keyword><keyword><style  face="normal" font="default" size="100%">Native medicine</style></keyword><keyword><style  face="normal" font="default" size="100%">Stroke</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">102-106</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Context:&lt;/strong&gt; A stroke or cerebrovascular disease is an abrupt onset of neurological deficit that is attributable to a focal vascular cause. Antiplatelet drugs, anticoagulants and thrombolytics are used in ischemic stroke. Indrakeeladri, is a village in Andhra Pradesh in India where traditional local practitioners prescription has long been practiced for treatment of stroke by using unknown and undisclosed formulation (gulikalu) without any name and labeling. Patients who have taken treatment at Indrakeeladri have noticed improvement in their symptoms particularly in speech. &lt;strong&gt;Aims:&lt;/strong&gt; We endeavoured to analyze the formulation to know its composition as this analysis might help us in preparation of newer drugs for stroke. &lt;strong&gt;Settings and Design:&lt;/strong&gt; GC MS analysis. &lt;strong&gt;Methods and Material:&lt;/strong&gt; The sample was powdered and tested for its solubility in different solvents of increased polarity strength and then subjected to Gas Chromatography Mass Spectrometry (GCMS) analysis in order to know its chemical components. &lt;strong&gt;Results:&lt;/strong&gt; The sample was soluble only in water. The GC-MS analysis of the test sample revealed the presence of methyl tetradecanoate, dodecanoic acid methyl ester and methyl 10-methyl undecanoate as the major constituents. These substances are known to have inhibitory effect on blood coagulation.&lt;strong&gt; Conclusions:&lt;/strong&gt; Further studies need to be carried out to find out whether these components of native medicine have a role in the treatment of stroke or not.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">102</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Sundarachary Nagarjunakonda&lt;sup&gt;1&lt;/sup&gt;, Sridhar Amalakanti&lt;sup&gt;2&lt;/sup&gt;, Sristi Ram Dhishana&lt;sup&gt;3&lt;/sup&gt;, Maddi Ramaiah&lt;sup&gt;4&lt;/sup&gt;, Lalitha Rajanala&lt;sup&gt;5 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Neurology, Guntur Medical College, Guntur, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Neurology, Guntur Medical College, Guntur, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Intern, Guntur Medical College, Guntur.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Pharmacognosy, Hindu College of Pharmacy, Guntur, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Neurology, Guntur Medical College, Guntur, INDIA.&lt;/p&gt;</style></auth-address></record></records></xml>