<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Cennet Ragbetli</style></author><author><style face="normal" font="default" size="100%">Semiha Dede</style></author><author><style face="normal" font="default" size="100%">Feride Koc</style></author><author><style face="normal" font="default" size="100%">Veysel Yuksek</style></author><author><style face="normal" font="default" size="100%">Murat Cetin Ragbetli</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Serum Protein Fractions in Streptozotocin (STZ) Administrated Rat Models</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">electrophoresis</style></keyword><keyword><style  face="normal" font="default" size="100%">experimental diabetes</style></keyword><keyword><style  face="normal" font="default" size="100%">Rat</style></keyword><keyword><style  face="normal" font="default" size="100%">serum proteins</style></keyword><keyword><style  face="normal" font="default" size="100%">STZ</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">35-38</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Experimental diabetes can be induced using chemical agents such as streptozotocin. &lt;strong&gt;Objective:&lt;/strong&gt; This study aimed to investigate the effect of streptozotocin (STZ) which is most important agent to produce experimental diabetic model at two different doses on serum protein fractions in rat models. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Twenty-four male rats that weighed an average of 250 g and were 3&amp;ndash;4 months old were used as the experimental models. They were sorted into three groups composed of eight rats each of STZ 55 mg/kg, STZ 65 mg/kg and control. Diabetes was induced by administering STZ 55 mg/kg and 65 mg/kg intraperitoneally. The serum protein fractions were analyzed by cellulose acetate electrophoresis. &lt;strong&gt;Results:&lt;/strong&gt; No significant difference was observed between the groups for all fractions except alpha-2 and beta globulins. The alpha-2 and beta globulin levels were significantly higher in the 55 mg/kg group than in the 65 mg/kg STZ and control groups (p&amp;lt;0.05). &lt;strong&gt;Conclusion:&lt;/strong&gt; This increase may be due to the involvement of different proteins in the alpha-2 and beta globulin protein fractions.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">35</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Cennet Ragbetli&lt;sup&gt;1&lt;/sup&gt;, Semiha Dede&lt;sup&gt;2&lt;/sup&gt;*, Feride Koc&lt;sup&gt;3&lt;/sup&gt;, Veysel Yuksek&lt;sup&gt;4&lt;/sup&gt;, Murat Cetin Ragbetli&lt;sup&gt;5&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Microbiology, Medicine Faculty, Veterinary Medicine School, Van, 65080 TURKEY.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biochemistry, Veterinary Medicine Faculty, Veterinary Medicine School, Van, 65080 TURKEY.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department Pharmacology and Toxicology, Veterinary Faculty Erciyes University, Veterinary Medicine School, Biochemistry Department, Van, 65080 Turkey.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Ozalp Vocational High School, YuzuncuYil University, Veterinary Medicine School, Van, 65080 TURKEY.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Histology and Embryology, Medicine Faculty, Veterinary Medicine School, Biochemistry Department, Van, 65080 TURKEY.&lt;/p&gt;
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