<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Retno Budiarti</style></author><author><style face="normal" font="default" size="100%">Ediono</style></author><author><style face="normal" font="default" size="100%">Muhammad Miftahussurur</style></author><author><style face="normal" font="default" size="100%">Abdulloh Machin</style></author><author><style face="normal" font="default" size="100%">Mochammad Wijdan Rosyich</style></author><author><style face="normal" font="default" size="100%">Ayu Imamatun Nisa</style></author><author><style face="normal" font="default" size="100%">Fatimatuzzahro</style></author><author><style face="normal" font="default" size="100%">Nila Novia Putri</style></author><author><style face="normal" font="default" size="100%">Muhammad Ja’far Shodiq</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Biomarker Profiles Associated with Covid-19 Mortality in East Java, Indonesia: A Tertiary Care Hospital Study</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Biomarker</style></keyword><keyword><style  face="normal" font="default" size="100%">COVID-19</style></keyword><keyword><style  face="normal" font="default" size="100%">Outcome</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">689-694</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; This study aimed to compare the most useful biomarkers for predicting prognosis and response to therapy in COVID-19 patients. &lt;strong&gt;Material and Methods:&lt;/strong&gt; This quantitative study involved 639 patients who were hospitalized with COVID-19 infection. Patients without any biochemical marker result; patients referred to another hospital; and peripheral oxygen levels measured using oxygen supplementation were excluded from the study. &lt;strong&gt;Results: &lt;/strong&gt;There was a statistically significant difference in terms of demographics, vital signs on admission, and laboratory parameters. The risk of mortality in COVID-19 is significantly influenced by c-reactive protein (CRP) and interleukin-6 (IL-6) levels (p-value &amp;lt;0.05). &lt;strong&gt;Conclusion:&lt;/strong&gt; Findings revealed these biomarkers could help the future development of more personalized treatment and diagnostic approaches.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">689</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Retno Budiarti&lt;sup&gt;1&lt;/sup&gt;*, Ediono&lt;sup&gt;2&lt;/sup&gt;, Muhammad Miftahussurur&lt;sup&gt;3,4&lt;/sup&gt;, Abdulloh Machin&lt;sup&gt;5,7&lt;/sup&gt;, Wiwin Is Effendi&lt;sup&gt;5,6&lt;/sup&gt;, Mochammad Wijdan Rosyich&lt;sup&gt;7&lt;/sup&gt;, Ayu Imamatun Nisa’&lt;sup&gt;8&lt;/sup&gt;, Fatimatuzzahro’&lt;sup&gt;8&lt;/sup&gt;, Nila Novia Putri&lt;sup&gt;7&lt;/sup&gt;, Muhammad Ja’far Shodiq&lt;sup&gt;7&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Microbiology, Faculty of Medicine, Hang Tuah University, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Pulmonology Department, Naval Hospital, RSAL Dr. Ramelan, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Division of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine / Dr. Soetomo Teaching Hospital, Airlangga University, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;4&lt;/sup&gt;Helicobacter Pylori and Microbiota Study Group, Institute of Tropical Disease, Airlangga University, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;5&lt;/sup&gt;Infectious Hospital, Airlangga University, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Airlangga University, Surabaya&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;7&lt;/sup&gt;Neurology Department, Faculty of Medicine / Dr. Soetomo Teaching Hospital, Airlangga University, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;8&lt;/sup&gt;Faculty of Medicine, Airlangga University, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Wardah Rahmatul Islamiyah</style></author><author><style face="normal" font="default" size="100%">Nasronudin</style></author><author><style face="normal" font="default" size="100%">Abdulloh Machin</style></author><author><style face="normal" font="default" size="100%">Iin Ernawati</style></author><author><style face="normal" font="default" size="100%">Yunita Dwi Tanti</style></author><author><style face="normal" font="default" size="100%">Nur Jaya</style></author><author><style face="normal" font="default" size="100%">Farah Medina</style></author><author><style face="normal" font="default" size="100%">Fathia Faza Rahmadanita</style></author><author><style face="normal" font="default" size="100%">Paulus Sugianto</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Analysis of The Effect of Leptin, AMPK, Adiponectin, and NPY Markers on Changes in Body Weight of Childhood Epileptic Using Valproic Acid Monotherapy</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adiponectin</style></keyword><keyword><style  face="normal" font="default" size="100%">AMPK</style></keyword><keyword><style  face="normal" font="default" size="100%">Childhood.</style></keyword><keyword><style  face="normal" font="default" size="100%">Epilepsy</style></keyword><keyword><style  face="normal" font="default" size="100%">Leptin</style></keyword><keyword><style  face="normal" font="default" size="100%">NPY</style></keyword><keyword><style  face="normal" font="default" size="100%">Valproic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">Weight gain</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">150-153</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction&lt;/strong&gt;: Epilepsy is a neurological disorder that occurs due to abnormal neurons in the brain and an imbalance between excitation and inhibition in the central nervous system. The first line of OAE in children is VPA (Valproate Acid). However, long-term use can cause weight gain with a frequency of 10-70%. The underlying mechanism of weight gain in patients remains unclear. &lt;strong&gt;Purpose: &lt;/strong&gt;This study aimed to analyze the relationship between levels of biomarkers AMPK, NPY, Leptin, and Adiponectin on changes in body weight in patients with epileptic seizures using VPA monotherapy. Method: This study is an observational cohort design. Data collection in April-June 2019. Inclusion criteria were children aged 2-10 years who used VPA requirement less than two years, not taking any drugs that affect body weight, not diagnose systemic lupus, nephrotic syndrome, and diabetes mellitus. Bodyweight and all biomarkers measurement on subjects who came to the clinic at the time of study and at least after one month of taking VPA. A total of 17 subjects participated in this study.&lt;strong&gt; Result: &lt;/strong&gt;The results of the statistical multivariate analysis test of VPA dosage on changes in body weight and biomarker levels found that Leptin, AMPK, Adiponectin did not significantly increase in body weight (p&amp;gt;0.05), but NPY significant increase in body weight (p&amp;lt;0.05). &lt;strong&gt;Conclusion:&lt;/strong&gt; NPY is the most potent for appetite enhancing, preferential effect on carbohydrate intake, weight regulation, energy storage, and expenditure. Increase production of NPY, there is an increase in energy intake and then increases fat storage and body weight.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">150</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Wardah Rahmatul Islamiyah1&lt;sup&gt;,2&lt;/sup&gt;, Nasronudin&lt;sup&gt;3,4,*&lt;/sup&gt;, Abdulloh Machin&lt;sup&gt;2&lt;/sup&gt;, Iin Ernawati&lt;sup&gt;5&lt;/sup&gt;, Yunita Dwi Tanti&lt;sup&gt;6&lt;/sup&gt;, Nur Jaya&lt;sup&gt;7&lt;/sup&gt;, Farah Medina&lt;sup&gt;8&lt;/sup&gt;, Fathia Faza Rahmadanita&lt;sup&gt;9&lt;/sup&gt;, Paulus Sugianto&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Doctoral Program of Medical Science, Faculty of Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Neurology, Faculty of Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Universitas Airlangga Hospital, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Departement of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Akademi Farmasi Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Ngudi Waluyo Hospital Wlingi Blitar, INDONESIA. 7Budi Agung Hospital, Palu, INDONESIA. 8Oncology Hospital, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;9&lt;/sup&gt;Faculty of Medicine and Health Science Maulana Malik Ibrahim State Islamic University Malang, Malang, INDONESIA.&lt;/p&gt;
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