<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Candra Irawan</style></author><author><style face="normal" font="default" size="100%">Maman Sukiman</style></author><author><style face="normal" font="default" size="100%">Ismail</style></author><author><style face="normal" font="default" size="100%">Imalia Dwi Putri</style></author><author><style face="normal" font="default" size="100%">Andita Utami</style></author><author><style face="normal" font="default" size="100%">Andrean Nur Pratama</style></author><author><style face="normal" font="default" size="100%">M. Ilham Kumala Zalni</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant Capacity and Potential as an Alpha-Glucosidase Inhibitor in Phaleria macrocarpa (Scheff.) Boerl Fruit Peel Ultrasonic Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alpha-glucosidase</style></keyword><keyword><style  face="normal" font="default" size="100%">Antidiabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Phaleria macrocarpa (Scheff.) Boerl</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">305-312</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;em&gt;Phaleria macrocarpa &lt;/em&gt;(Scheff.) Boerl is native to the tropical region of Papua Island, Indonesia, and has traditionally been used as a herbal drink, either alone or in combination with other medicinal plants, to treat diseases such as cancer, hypertension, and diabetes mellitus. This study aimed to obtain the fruit peel extract of &lt;em&gt;Phaleria macrocarpa&lt;/em&gt; (Scheff.) Boerl. through the application of ultrasound-assisted extraction (UAE) with variations in time and amplitude to produce optimal extraction conditions. The potential of the extract as an antioxidant using the cupric ion reducing antioxidant capacity (CUPRAC) and ferric reducing antioxidant power (FRAP) methods, and its potential as an antidiabetic through alpha glucosidase inhibition. The optimum extract selected was extract C (extraction time was 45 minutes and amplitude 60%) with IC&lt;sub&gt;50&lt;/sub&gt; values for antioxidant activity in the CUPRAC method of 39.63 ± 0.009 mg/L and the FRAP method of 77.37 ± 0.8 mg/L, while the inhibition of alpha glucosidase was 0.45 ± 0.007 mg/L. It can be concluded that the ethanol extract of &lt;em&gt;Phaleria macrocarpa &lt;/em&gt;fruit peel has the potential as a source of antioxidants and anti-diabetic.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><accession-num><style face="normal" font="default" size="100%">08</style></accession-num><section><style face="normal" font="default" size="100%">305</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Candra Irawan&lt;sup&gt;1&lt;/sup&gt;, Maman Sukiman&lt;sup&gt;2,*&lt;/sup&gt;, Ismail&lt;sup&gt;3&lt;/sup&gt;, Imalia Dwi Putri&lt;sup&gt;1&lt;/sup&gt;, Andita Utami&lt;sup&gt;3&lt;/sup&gt;, Andrean Nur Pratama&lt;sup&gt;4&lt;/sup&gt;, M. Ilham Kumala Zalni&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Food Nanotechnology, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Industrial Waste Treatment, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Chemical Analysis, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;4&lt;/sup&gt;Research and Development Planning Agency, Tanggamus District, Lampung, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ismail</style></author><author><style face="normal" font="default" size="100%">Candra Irawan</style></author><author><style face="normal" font="default" size="100%">Maman Sukiman</style></author><author><style face="normal" font="default" size="100%">Imalia Dwi Putri</style></author><author><style face="normal" font="default" size="100%">Andita Utami</style></author><author><style face="normal" font="default" size="100%">M. Ilham Kumala Zalni</style></author><author><style face="normal" font="default" size="100%">Ratna Komala Putri</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Optimization of Ultrasound-Assisted Extraction of Andrographis paniculata Nees Leaves, Phytochemical Screening, Total Phenolic Content and Anti-Gout Potential Activity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Andrographis paniculata Nees</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-gout</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical screening</style></keyword><keyword><style  face="normal" font="default" size="100%">total phenolic content</style></keyword><keyword><style  face="normal" font="default" size="100%">Ultrasound-assisted extraction</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">432-438</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Gout is a type of arthritis that causes painful inflammation in one or more joints. In gout, an increase in uric acid in the blood triggers the formation of crystals, causing joint pain. Indonesia is a country rich in the biodiversity of medicinal plant species. Therefore, its flora offers promising therapy for gout, one of which is&lt;em&gt; Andrographis paniculata &lt;/em&gt;Nees. This study aims to obtain the leaf extract of &lt;em&gt;A. paniculata &lt;/em&gt;through the application of ultrasound-assisted extraction (UAE) with variations in time and amplitude to produce optimal extraction conditions. Then the extract obtained was subjected to phytochemical screening, a total phenolic content test and uric acid test. The results of phytochemical screening of &lt;em&gt;A. paniculata&lt;/em&gt; leaf extract using UAE contained saponins, phenols, tannins and alkaloids. The high total phenolic content has an effect on the high potential for reducing uric acid levels. Sample B with a time variation of 35 minutes and an amplitude of 65% showed the highest total phenolic content and potential for reducing uric acid levels compared to the other samples, which were 1104.53 ± 0.5 mg GAE/g extract and 72.81±0.2 %, respectively. From the results of the study, it can be concluded that the UAE extract from the leaves of &lt;em&gt;A. paniculata&lt;/em&gt; has good potential as an anti-gout agent.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">432</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ismail&lt;sup&gt;1&lt;/sup&gt;, Candra Irawan&lt;sup&gt;2&lt;/sup&gt;, Maman Sukiman&lt;sup&gt;3,*&lt;/sup&gt;, Imalia Dwi Putri&lt;sup&gt;2&lt;/sup&gt;, Andita Utami&lt;sup&gt;1&lt;/sup&gt;, M. Ilham Kumala Zalni&lt;sup&gt;3&lt;/sup&gt;, Ratna Komala Putri&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Chemical Analysis, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Food Nanotechnology, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Industrial Waste Treatment, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;
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