<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">N Aji</style></author><author><style face="normal" font="default" size="100%">S Kumala</style></author><author><style face="normal" font="default" size="100%">E Mumpuni</style></author><author><style face="normal" font="default" size="100%">D Rahmat</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antibacterial Activity and Active Fraction of Zingiber officinale Roscoe, Zingiber montanum (J.Koenig) Link ex A., and Zingiber zerumbet (L.) Roscoe ex Sm. Against Propionibacterium acnes</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">103-111</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Propionibacterium acnes is a commensal bacteria that play a role in developing acne vulgaris on the skin. Antibacterial activity assay in the last decades have shown that Propionibacterium acnes is resistant to several antibiotics. Potential zingiber genera such as &lt;em&gt;Z. officinale&lt;/em&gt;, Z. montanum, and&lt;em&gt; Z. zerumbet&lt;/em&gt; have potential as antibacterial. &lt;strong&gt;Objective:&lt;/strong&gt; This study aims to compare the antibacterial activity of &lt;em&gt;Z. officinale,&lt;/em&gt; &lt;em&gt;Z. montanum&lt;/em&gt; and Z. zerumbet against Propionibacterium acnes, the active fraction, and the components of the active fraction of the plant. &lt;strong&gt;Materials and Methods&lt;/strong&gt;: Antibacterial activity test using agar diffusion method, extracts with high antibacterial activity were partitioned with water: n-hexane, n-hexane: methanol, water: ethyl acetate. The fraction was tested for antibacterial activity against P. acnes. The active fraction obtained was identified for its phytochemical content using TLC and GC-MS methods.&lt;strong&gt; Results:&lt;/strong&gt; The results of the antibacterial activity test of&lt;em&gt; Z. officinale &lt;/em&gt;extract had a larger inhibition zone. The test results of the active fraction&lt;em&gt; Z. officinale&lt;/em&gt; had a higher activity than the extract. The results of screening using the GC-MS method obtained that the main components identified from &lt;em&gt;Z. officinale&lt;/em&gt; were volatile oil components (α-curcumene, α-zingiberene and zingerone) and oleoresin (6-shogaol). &lt;strong&gt;Conclusion: &lt;/strong&gt;Extracts of &lt;em&gt;Z. officinale&lt;/em&gt;, &lt;em&gt;Z. montanum &lt;/em&gt;and &lt;em&gt;Z. zerumbet &lt;/em&gt;had antibacterial activity against P. acnes. The highest antibacterial activity in&lt;em&gt; Z. officinal&lt;/em&gt;e both extract and ethyl acetate fraction which is known to contain terpenoids and oleoresin compounds (6-shogaol).&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Key words&lt;/strong&gt;: Antibacterial, Zingiber officinale, Zingiber montanum, Zingiber zerumbeth, Propionibacterium acnes.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">103</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;N Aji&lt;sup&gt;1,2*&lt;/sup&gt;, S Kumala&lt;sup&gt;1*&lt;/sup&gt;, E Mumpuni&lt;sup&gt;1&lt;/sup&gt;, D Rahmat&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, Pancasila University, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacy, Poltekkes Kemenkes Tasikmalaya, Tasikmalaya, INDONESIA.&lt;/p&gt;
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