<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Diah Dhianawaty</style></author><author><style face="normal" font="default" size="100%">Resti Gradia Dwiwina</style></author><author><style face="normal" font="default" size="100%">Wulan Mayasari</style></author><author><style face="normal" font="default" size="100%">Achadiyani</style></author><author><style face="normal" font="default" size="100%">Ruslin</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantification of Four Phytochemical Parameters of Imperata cylindrica Leaves to Promote Its Use as A Medicinal Plant</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Imperata cylindrica leaves</style></keyword><keyword><style  face="normal" font="default" size="100%">total flavonoid content</style></keyword><keyword><style  face="normal" font="default" size="100%">total phenolic content</style></keyword><keyword><style  face="normal" font="default" size="100%">Total Tannin content</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">108-117</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; The benefits of Imperata cylindrica (I. cylindrica) leaves and their relationship to the content of phytochemical compounds have been widely studied. The aim of this study was to promote I. cylindrica leaves from Kertajati Subdistrict in Majalengka Regency in their use as a medicinal plant based on the four parameters, namely the content of total phenolic content, total flavonoid content, total tannin content, and antioxidant activity. The four parameters that become the basis for the benefits of the leaves were compared with the four parameters of the roots. &lt;strong&gt;Methods:&lt;/strong&gt; Quantification of total phenolic content, total flavonoid content, total tannin content, and antioxidant activity used Folin-Ciocalteu, aluminium chloride, Fe(III) chloride and 1.10-Phenanthroline, and 1,1-diphenyl-2-pikrilhidrazil (DPPH) methods, respectively. All methods used visible spectrophotometric method. &lt;strong&gt;Results: &lt;/strong&gt;The percentages of total phenolic content, total flavonoid content, total tannin content, and IC50 of antioxidant activity of I. cylindrica leaves extract were 9% (GAE), 2.1% (QE), 5.6% (TAE), and 100.5 ppm, respectively. Then, the percentages of I. cylindrica roots extract showed the percentages of total phenolic content, total flavonoid content, total tannin content, and IC50 of antioxidant activity were 5.8% (GAE), 0.64% (QE), 3% (TAE), and 241 ppm, respectively.&lt;strong&gt; Conclusion:&lt;/strong&gt; The extract of I. cylindrica leaves contained the phenolic compound, namely flavonoids, tannins and other phenolic compounds, and had antioxidant activity. All parameters have been reported to have positive effect on health. Therefore, the leaves of I. cylindrica from Kertajati Subdistrict are discovered to have effects on health which are suitable to be promoted as a medicinal plant.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">108</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Diah Dhianawaty&lt;sup&gt;1&lt;/sup&gt;*, Resti Gradia Dwiwina&lt;sup&gt;1&lt;/sup&gt;, Wulan Mayasari&lt;sup&gt;1&lt;/sup&gt;, Achadiyani1, Ruslin&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Pharmacy, Halu Oleo University, Kendari, Southeast Sulawesi, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Diah Dhianawaty</style></author><author><style face="normal" font="default" size="100%">Resti Gradia Dwiwina</style></author><author><style face="normal" font="default" size="100%">Resti Gradia Dwiwina</style></author><author><style face="normal" font="default" size="100%">Achadiyani</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Study of Profile of the Government Programs Implementation Germas and Traditional Medicine between Two Generations in a Rural Area</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Fruit consumtion</style></keyword><keyword><style  face="normal" font="default" size="100%">Traditional medicine</style></keyword><keyword><style  face="normal" font="default" size="100%">Vegetable consumtion</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">1004-1009</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; The aim of the study was to discover the implementation of the government regulations, such as the healthy living community movements (GERMAS) and utilization of&lt;em&gt; jamu&lt;/em&gt; (herbal medicine/ traditional medicine) in village communities.&lt;strong&gt; Methods:&lt;/strong&gt; The respondents in study were three groups: village cadres (they represented senior generation), junior high school students, and senior high school students (they represented young generation). All respondents were given the same questions, namely the frequency of eating vegetables and fruits; their favorite vegetable and fruit; knowledge of spices used as&lt;em&gt; jamu&lt;/em&gt;. Especially, the senior group was given additional questions regarding what was their purpose in drinking&lt;em&gt; jamu &lt;/em&gt;and how they got the &lt;em&gt;jamu&lt;/em&gt;.&lt;strong&gt; Results:&lt;/strong&gt; The total frequency of vegetable consumption for 3-7 days/week from three groups of respondents, namely village cadres, senior high school and junior high school students, were 98%, 88% and 68% respectively; the frequency of fruit consumption were 86%, 92% and 90% respectively. The favorite vegetable and fruit were&lt;em&gt; Ipomoea aquatica&lt;/em&gt; and &lt;em&gt;Musa paradisiaca&lt;/em&gt;, respectively. The knowledge regarding the benefits of spices as traditional medicine, the two spices were mostly known by all respondents were&lt;em&gt; Curcuma longa&lt;/em&gt; and &lt;em&gt;Zingiber officinale&lt;/em&gt;. The percentage knowledge for &lt;em&gt;Curcuma longa&lt;/em&gt; were 32.47%, 23.81%, 23.45% respectively; and &lt;em&gt;Zingiber officinale &lt;/em&gt;were 23.38%, 27.89%, 29.66% respectively. The purpose of drinking&lt;em&gt; jamu&lt;/em&gt; for maintain health and knowledge to make jamu were 91% and 15.2%, respectively. &lt;strong&gt;Conclusion:&lt;/strong&gt; Based on the results as previously described, the government regulations (Germas and use of &lt;em&gt;jamu&lt;/em&gt;) in the village was continuous between the two generations.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1004</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Diah Dhianawaty&lt;sup&gt;1*&lt;/sup&gt;, Resti Gradia Dwiwina&lt;sup&gt;2&lt;/sup&gt;, Wulan Mayasari&lt;sup&gt;3&lt;/sup&gt;, Achadiyani&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biomedical Sciences, Division of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biomedical Sciences, Division of Cell Biology, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Biomedical Sciences, Division of Anatomy, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Diah Dhianawaty</style></author><author><style face="normal" font="default" size="100%">Resti Gradia Dwiwina</style></author><author><style face="normal" font="default" size="100%">Wulan Mayasari</style></author><author><style face="normal" font="default" size="100%">Achadiyani</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Preliminary Exploration of Traditional Medicine Formulas as A Basis of Effort and Support Toward Traditional Medicines Developing Use and Implementation in The Government Healthcare Program</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Healthy living communities.</style></keyword><keyword><style  face="normal" font="default" size="100%">Traditional medicine</style></keyword><keyword><style  face="normal" font="default" size="100%">Traditional medicine formulations</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">279-284</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Develop the healthy living communities with enhance ability of community in using herbs or traditional medicine in the family health system was supported by the government regulations.&lt;strong&gt; Materials and Method&lt;/strong&gt;: The study only took point 3 out of 10 points Essential Public Health Services. The point was to inform and educate the public about health, the factors that influence it, and efforts to improve it. This point was realized by collecting and selecting the formulas that have been published by the government to be summarized based on the indication of disease, quantity of herbs and water (including the parts of herb), processing of formulation and drinking rules, etc. &lt;strong&gt;Results: &lt;/strong&gt;17 Formulations of traditional medicinal herbs are valuable for the indication of diseases: arthritis, reduce blood fat /blood cholesterol, reduce blood glucose, reduce body weight, maintaining the health conditions of cancer patient, cough, diabetes mellitus, gastritis, gout, hemorrhoids, reduce high blood pressure, liver problem, nausea and vomiting, uric acid, increase urine volumes, urinary stone/kidney stone, and physical fitness. &lt;strong&gt;Conclusion: &lt;/strong&gt;The formulas could be used and was introduced to the community for encouraging health literacy, empowering the community to build a family health system. Finally, the exploration of traditional medicine formulas could support the developing use and implementation of traditional medicines in the Government Healthcare Program.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><section><style face="normal" font="default" size="100%">279</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Diah Dhianawaty&lt;sup&gt;1,*&lt;/sup&gt;, Resti Gradia Dwiwina&lt;sup&gt;2&lt;/sup&gt;, Wulan Mayasari&lt;sup&gt;3&lt;/sup&gt;, Achadiyani&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biomedical Sciences, Division of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biomedical Sciences, Division of Cell Biology, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Biomedical Sciences, Division of Anatomy, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Resti Gradia Dwiwina</style></author><author><style face="normal" font="default" size="100%">Achadiyani</style></author><author><style face="normal" font="default" size="100%">Dyah Dhianawaty</style></author><author><style face="normal" font="default" size="100%">Irma Ruslina Defi</style></author><author><style face="normal" font="default" size="100%">Nur Atik</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Preliminary Identification and Quantification of Quercetin Concentration and Its Comparison in Psidium Guajava L. (Guava) Fruit Ethanol Extract 50% and 70%</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ethanol extract.</style></keyword><keyword><style  face="normal" font="default" size="100%">Psidium Guajava L.</style></keyword><keyword><style  face="normal" font="default" size="100%">Quercetin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">399-405</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;In 80 % of developing countries as stated by official fact sheets and report a large proportion of the society still relies on traditional practitioners and their armamentarium of medicinal plants in order to meet health care needs. The study on &lt;em&gt;Psidium Guajava &lt;/em&gt;L. fruit ethanol extract from Dukuhwaluh village, Purwokerto, Central Java, Indonesia showed its potential in increasing the number of megakaryocytes, followed by the rise of thrombocyte values. The study's objective was to compare the quantity of the quercetin content in 50% and 70% ethanol. This study was of experimental design and began by determining the effective concentration of two groups of guava fruits ethanol extract. The percentage of quercetin content dissolved within 50% ethanol was 54.7344 mg/kg, and 70% ethanol was 28.8420 mg/kg respectively. Quercetin content of &lt;em&gt;Psidium Guajava &lt;/em&gt;L. fruit ethanol extract fruits in 50% hydroethanolic was higher than that of 70% hydroethanolic extract.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">399</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Resti Gradia Dwiwina&lt;sup&gt;1&lt;/sup&gt;, Achadiyani&lt;sup&gt;1&lt;/sup&gt;, Dyah Dhianawaty&lt;sup&gt;2&lt;/sup&gt;, Irma Ruslina Defi&lt;sup&gt;3&lt;/sup&gt;, Nur Atik&lt;sup&gt;1,*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biomedical Sciences, Division of Cell Biology, Faculty of Medicine, Universitas Padjadjaran Jalan Raya Bandung - Sumedang Km. 21 Jatinangor, Sumedang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biomedical Sciences, Division of Biochemistry and Molecular Biology, Universitas Padjadjaran, Jalan Raya Bandung - Sumedang Km. 21 Jatinangor, Sumedang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Physical Medic and Rehabilitation, Universitas Padjadjaran, Jalan Eijkman No. 38, Bandung, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Diah Dhianawaty</style></author><author><style face="normal" font="default" size="100%">Nur Atik</style></author><author><style face="normal" font="default" size="100%">Resti Gradia Dwiwina</style></author><author><style face="normal" font="default" size="100%">Iskandar Muda</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Preliminary Identification and Quantification of Four Secondary Metabolites, Total Tannin and Total Flavonoid Contents in Guava Fruit Ethanol Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Flavonoid</style></keyword><keyword><style  face="normal" font="default" size="100%">Guava fruit</style></keyword><keyword><style  face="normal" font="default" size="100%">Psidium guajava</style></keyword><keyword><style  face="normal" font="default" size="100%">Tannin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">350-357</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;The study on guava fruit ethanol extract from Dukuhwaluh Village, Purwokerto, Central Java, Indonesia showed increased megakaryocytes and platelet numbers in thrombocytopenic mice model. The study of acute oral toxicity of the extract did not show toxic effects in the kidney and liver at doses of 2000 and 5000 mg/kg b.w. The aim of the study was to determine the profile and quantity of four metabolite compounds and total tannin and flavonoid in the extract. &lt;strong&gt;Materials and Method&lt;/strong&gt;: gallic acid, ellagic acid, rutin and kaemferol in the extract were identified and quantified by using high-performance liquid chromatography (HPLC) method with column LiChroCART 250-4,6 RP 18E, isocratic mobile phases with the composition of mixture:0.1% acetic acid, acetonitrile and methanol (40:50:10) respectively, and at temperature 300C. The total tannin and flavonoid were determined using the by spectrophotometry method, Fe(III) chloride and 1.10-phenanthroline at wavelength 510 nm for tannin and aluminium chloride and rutin at wavelength 422 nm for flavonoid, respectively. &lt;strong&gt;Results: &lt;/strong&gt;Percentage of gallic acid, ellagic acid, rutin and kaempferol were 0.77%, 1.37 %, 0.41 % and 0.35 %, respectively. Total tannin and flavonoid contents were 1.20% (TAE) and, 1.18% (RE) respectively. &lt;strong&gt;Conclusion&lt;/strong&gt;: The guava fruit ethanol extract contained gallic acid, ellagic acid, rutin, kaempferol, tannin and flavonoid.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article </style></work-type><section><style face="normal" font="default" size="100%">350</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Diah Dhianawaty&lt;sup&gt;1,*&lt;/sup&gt;, Nur Atik&lt;sup&gt;2&lt;/sup&gt;, Resti Gradia Dwiwina&lt;sup&gt;2&lt;/sup&gt;, Iskandar Muda&lt;/strong&gt;&lt;sup&gt;&lt;strong&gt;3&lt;/strong&gt; &lt;/sup&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biomedical Sciences, Division of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biomedical Sciences, Division of Cell Biology, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Diploma of Nursing Program, Faculty of Medicine, Mulawarman University, Samarinda, East Kalimantan, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Diah Dhianawaty</style></author><author><style face="normal" font="default" size="100%">Mas Rizky Anggun Adipurna Syamsunarno</style></author><author><style face="normal" font="default" size="100%">Resti Gradia Dwiwina</style></author><author><style face="normal" font="default" size="100%">Raden Anita Indriyanti</style></author><author><style face="normal" font="default" size="100%">Ruslin</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Separation and Quantification of Sinensetin, Imperatorin and Total Tannin Content as Active Phytoconstituents of Methanol Extract of Imperata cylindrica Root from Kendari</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Imperata cylindrica</style></keyword><keyword><style  face="normal" font="default" size="100%">Imperatorin</style></keyword><keyword><style  face="normal" font="default" size="100%">Sinensetin</style></keyword><keyword><style  face="normal" font="default" size="100%">Tannin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1216-1224</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt;&lt;em&gt; Imperata cylindrica&lt;/em&gt; root methanol extract harvested from Kendari had anti-hypertensive activity stated in a study on hypertension rat models at the doses 60 and 90 mg/kg-bw. The extract also contained phenolic compound 1.53% (GAE) and flavonoid 1.17% (QE) and had antioxidant activity IC&lt;sub&gt;50 &lt;/sub&gt;0.32 mg/mL. Aim of the study was to determine the active secondary metabolites in the extract. &lt;strong&gt;Materials and Method: &lt;/strong&gt;Sinensetin and imperatorin in the extract were separated on silica gel 60 column, eluted with a gradient eluent system as follows (1) n-hexane- ethyl acetate (3:7); (2) n-hexane – ethyl acetate (2:8); (3) ethyl acetate -MeOH (8:2), and (4) methanol. Imperatorin and sinensetin in fractions were identified and quantified by HPLC method with column LiChroCART 250-4,6 RP 18E, isocratic mobile phases with the composition of mixture as follows, 0.1% formic acid, acetonitrile and methanol (40:50:10) respectively, and at temperature 400 C. The total tannin was determined by spectrophotometry method with Fe(III) chloride and 1.10-Phenanthroline at wave length 510 nm. &lt;strong&gt;Results:&lt;/strong&gt; Imperatorin and sinensetin were identified in fractions 5 to 9. The concentrations of sinensetin and imperatorin in &lt;em&gt;Imperata cylindrica&lt;/em&gt; root methanol extract were of 32.348 and 37.014 mg/kg extract, respectively. The total tannin content was 1.06 % (w/w) (TAE). &lt;strong&gt;Conclusion:&lt;/strong&gt; &lt;em&gt;Imperata cylindrica &lt;/em&gt;root methanol extract from Kendari had active phytoconstituents, namely sinensetin, imperatorin, and tannin.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1216</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Diah Dhianawaty&lt;sup&gt;1,&lt;/sup&gt;*, Mas Rizky Anggun Adipurna Syamsunarno&lt;sup&gt;1&lt;/sup&gt;, Resti Gradia Dwiwina&lt;sup&gt;2&lt;/sup&gt;, Raden Anita Indriyanti&lt;sup&gt; 3&lt;/sup&gt;, Ruslin&lt;sup&gt;4&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biomedical Sciences, Division of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biomedical Sciences, Division of Cell Biology, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmacology, Bandung Islamic University, Bandung, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Faculty of Pharmacy, Halu Oleo University, Kendari, Southeast Sulawesi, INDONESIA.&lt;/p&gt;
</style></auth-address></record></records></xml>