<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Roihatul Mutiah</style></author><author><style face="normal" font="default" size="100%">Wirda Ardania</style></author><author><style face="normal" font="default" size="100%">Arief Suryadinata</style></author><author><style face="normal" font="default" size="100%">Dewi Sinta Megawati</style></author><author><style face="normal" font="default" size="100%">Anik Listiyana</style></author><author><style face="normal" font="default" size="100%">Abdul Wafi</style></author><author><style face="normal" font="default" size="100%">Rahmi Annisa</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Influence of Chitosan Concentration on Characteristic of Microspheres Delivery System Prepared from Eleutherine palmifolia (L.) Merr. Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Characteristic</style></keyword><keyword><style  face="normal" font="default" size="100%">Chitosan</style></keyword><keyword><style  face="normal" font="default" size="100%">Delivery system.</style></keyword><keyword><style  face="normal" font="default" size="100%">Eleutherine palmifolia</style></keyword><keyword><style  face="normal" font="default" size="100%">Microspheres</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">702-709</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;Eleutherine palmifolia&lt;/em&gt; (L.) Merr. (E.palmifolia) is a medicinal plant containing naphthoquinone, isoliquiritigenin, and oxyresveratrol compound. This study aims to formulate and characterize the &lt;em&gt;E. palmifolia&lt;/em&gt; microspheres delivery system using chitosan variation as the polymer. &lt;strong&gt;Methods: &lt;/strong&gt;The preparation method was the solvent evaporation method. The microspheres delivery system was performed by variation of chitosan concentration in each formulation 0.637% (F1), 1.275% (F2), and 1.912% (F3). The physical and chemical characterizations include Entrapment Efficiency (EE), yield percentage, particle size, particle morphology, FTIR analysis, X-Ray Diffraction (XRD) analysis, and Differential Thermal Analysis (DTA) had been evaluated. &lt;strong&gt;Results&lt;/strong&gt;: The results showed that chitosan concentration variation affected the microsphere's physical and chemical characteristics. Variations in the concentration of chitosan polymer (0.637%, 1.275% and 1.912%) had an effect on the physical characteristics of the microspheres of the resulting Dayak onion bulb extract. The higher the concentration of chitosan used, the higher the entrapment efficiency and the yield yield will increase. Meanwhile, in observing the particle size, the higher the concentration of chitosan used, the smaller the particle size produced. The optimal concentration of chitosan as a polymer at concentration variations of 0.637%, 1.275% and 1.912% to provide good physical characteristics of the Dayak onion bulb extract microspheres was shown in formula 3 with a chitosan concentration of 1.912%. &lt;strong&gt;Conclusion:&lt;/strong&gt; The better characteristic was obtained upon higher chitosan concentration. The best physical characteristics of&lt;em&gt; E.palmifolia &lt;/em&gt;extract microspheres were obtained from chitosan concentration at 1.912% (F3).&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">702</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Roihatul Mutiah&lt;sup&gt;1&lt;/sup&gt;, Wirda Ardania&lt;sup&gt;2&lt;/sup&gt;, Arief Suryadinata&lt;sup&gt;3&lt;/sup&gt;, Dewi Sinta Megawati&lt;sup&gt;4&lt;/sup&gt;, Anik Listiyana&lt;sup&gt;5&lt;/sup&gt;, Abdul Wafi&lt;sup&gt;6&lt;/sup&gt;, Rahmi Annisa&lt;sup&gt;7,*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacy, Faculty of Medicine and Health Science, Maulana Malik Ibrahim State Islamic UniversityMalang, Malang, INDONESİA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacy, Faculty of Medicine and Health Science, Maulana Malik Ibrahim State Islamic University Malang, Malang, INDONESİA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmacy, Faculty of Medicine and Health Science, Maulana Malik Ibrahim State Islamic University Malang, Malang, INDONESİA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Pharmacy, Faculty of Medicine and Health Science, Maulana Malik Ibrahim State Islamic University Malang, Malang, INDONESİA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Medical Education, Faculty of Medical and Health Sciences, Maulana Malik Ibrahim State Islamic University Malang, Malang, INDONESİA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Pharmacy, Faculty of Medicine and Health Science, Maulana Malik Ibrahim State Islamic University Malang, Malang, INDONESİA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Department of Pharmacy, Faculty of Medicine and Health Science, Maulana Malik Ibrahim State Islamic University Malang, Malang, INDONESİA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Bayyinatul Muchtaromah</style></author><author><style face="normal" font="default" size="100%">Didik Wahyudi</style></author><author><style face="normal" font="default" size="100%">Mujahidin Ahmad</style></author><author><style face="normal" font="default" size="100%">Arif Nur Muhammad Ansori</style></author><author><style face="normal" font="default" size="100%">Rahmi Annisa</style></author><author><style face="normal" font="default" size="100%">Lil Hanifah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Chitosan-Tripolyphosphate Nanoparticles of Mango Ginger (Curcuma mangga) Extract: Phytochemical Screening, Formulation, Characterization, and Antioxidant Activity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Chemical identification</style></keyword><keyword><style  face="normal" font="default" size="100%">Chitosan</style></keyword><keyword><style  face="normal" font="default" size="100%">Mango ginger</style></keyword><keyword><style  face="normal" font="default" size="100%">Nanoparticles</style></keyword><keyword><style  face="normal" font="default" size="100%">TPP</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1065-1071</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Mango ginger (&lt;em&gt;Curcuma mangga&lt;/em&gt;) is one of Indonesia's medicinal plants widely used in most communities as a lust booster and for detoxifying purposes. Therefore, the purpose of this study is to synthesize chitosan-tripolyphosphate nanoparticles from mango ginger extract, determine their chemical contents, the nano chitosan characteristics, and its antioxidant activity. &lt;strong&gt;Methods:&lt;/strong&gt; In this study, we macerated mango ginger using 70% ethanol solvent, then performed phytochemical test and formulation of chitosan nanoparticles of mango ginger extract. The group of secondary metabolites that showed positive results with the reagent test was further identified through TLC. &lt;strong&gt;Results:&lt;/strong&gt; The results showed that the extract contained flavonoids and triterpenoids. Also, characterization of chitosan nanoparticles from the extract was conducted with FTIR test, PSA, XRD, and SEM. Based on the results, the nano chitosan particle size was 993 nm and examination with FTIR showed the presence of N-H and P=O groups, indicating ammonium ion interaction from chitosan with the polyanion from TPP and Mango ginger. Additionally, the XRD results showed that the crystals formed were in an amorphous form, which was supported by particle morphology images from SEM. Furthermore, the nanoparticles showed very strong antioxidant activity based on the reaction with DPPH. &lt;strong&gt;Conclusion:&lt;/strong&gt; Based on these results, the phytochemical identification of mango ginger extract showed positive results in flavonoid and triterpenoid compounds. In addition, based on the characterization of the nanoparticles, the mango ginger extract showed positive results, illustrating that the nano chitosan synthesis was successful. Furthermore, the nano chitosan has a very strong antioxidant activity with an IC50 value of 18.08 μg/mL.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1065</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Bayyinatul Muchtaromah&lt;sup&gt;1,&lt;/sup&gt;*, Didik Wahyudi&lt;sup&gt;1&lt;/sup&gt;, Mujahidin Ahmad&lt;sup&gt;1&lt;/sup&gt;, Arif Nur Muhammad Ansori&lt;sup&gt;2&lt;/sup&gt;, Rahmi Annisa&lt;sup&gt;3&lt;/sup&gt;, Lil Hanifah&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biology, Faculty of Science and Technology, Maulana Malik Ibrahim State Islamic University, Malang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Doctoral Program in Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmacy, Faculty of Medical and Health Sciences, Maulana Malik Ibrahim State Islamic University, Malang, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Bayyinatul Muchtaromah</style></author><author><style face="normal" font="default" size="100%">Didik Wahyudi</style></author><author><style face="normal" font="default" size="100%">Mujahidin Ahmad</style></author><author><style face="normal" font="default" size="100%">Rahmi Annisa</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Nanoparticle Characterization of Allium sativum, Curcuma mangga and Acorus calamus as a Basic of Nanotechnology on Jamu Subur Kandungan Madura</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Characterization</style></keyword><keyword><style  face="normal" font="default" size="100%">Garlic</style></keyword><keyword><style  face="normal" font="default" size="100%">Ionic gelation</style></keyword><keyword><style  face="normal" font="default" size="100%">Jeringau</style></keyword><keyword><style  face="normal" font="default" size="100%">Nanoparticle</style></keyword><keyword><style  face="normal" font="default" size="100%">Temu mangga</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1152-1159</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;The increasing of researcher attraction on the herbal drug after so long ignored due to difficulties in processing has opened a new door for the development of a novel of &quot;jamu Subur Kandungan&quot;. However, the constraints that then faced in consuming &quot;jamu Subur Kandungan&quot;, an herbal reproductive drug, are the solubility and poor absorption in the intestine. Therefore, this study aims to characterize nanoparticle of the combination of garlic (&lt;em&gt;Allium sativum&lt;/em&gt;), temu mangga (&lt;em&gt;Curcuma mangga&lt;/em&gt;) and jeringau (&lt;em&gt;Acorus calamus&lt;/em&gt;) encapsulated by chitosan. &lt;strong&gt;Material and Methods: &lt;/strong&gt;the simplicial of garlic (&lt;em&gt;Allium sativum&lt;/em&gt;), temu mangga (&lt;em&gt;Curcuma mangga&lt;/em&gt;) and jeringau (&lt;em&gt;Acorus calamus&lt;/em&gt;) was purchased from Materia Medica Batu Malang Indonesia. Nanoparticle of combination of garlic, temu mangga and jeringau was produced by ionic gelation method. Nanoparticle characterization was assessed by Scanning electron microscopy (SEM), Spectrophotometer Fourier Transform Infra-Red (FTIR), Particle Size analyzer (PSA) and X-ray diffraction (XRD).&lt;strong&gt; Result: &lt;/strong&gt;The ionic gelation method succeeded to make nanoparticle. The produced nanoparticle was around 438-1159 nm. The length of sonication has proven to make the particle size smaller. The particle size distribution of chitosan at the time of 90 min sonication and 150 min was classified as uneven because of the particle size clustered in the range 500-1000 nm and 3000-5000 nm. The hydroxyl (OH) group appeared at wave number 3429-2466 cm&lt;sup&gt;-1&lt;/sup&gt;, while the amide functional group appeared at wave numbers (1648-1652 cm&lt;sup&gt;-1&lt;/sup&gt;. Phosphate groups (P = O) also appeared, which is a TPP residue, at a wavenumber 1384 cm&lt;sup&gt;-1&lt;/sup&gt;. &lt;strong&gt;Conclusion:&lt;/strong&gt; Chitosan-garlic nanoparticles (Allium sativum), temu mangga (&lt;em&gt;Curcuma mangga&lt;/em&gt;) and jeringau (&lt;em&gt;Acorus calamus&lt;/em&gt;) were successfully produced with ionic gelation method.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1152</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Bayyinatul Muchtaromah&lt;sup&gt;1,&lt;/sup&gt;*, Didik Wahyudi&lt;sup&gt;1&lt;/sup&gt;, Mujahidin Ahmad&lt;sup&gt;1&lt;/sup&gt;, Rahmi Annisa&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Biology Department, Science and Technology Faculty, State Islamic University of Maulana Malik Ibrahim Malang, East Java, 65144, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacy, Faculty of Medical and Health Sciences, State Islamic University of Maulana Malik Ibrahim Malang, East Java, 65144, INDONESIA.&lt;/p&gt;
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