<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ribhu Ray</style></author><author><style face="normal" font="default" size="100%">Amrita Pal</style></author><author><style face="normal" font="default" size="100%">Santanu Paul</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Assessment of the Impact of Wild Stinkhorn Mushroom Extracts on Different Cancer Cell Proliferation and Study of Primary Metabolites</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">ABTS•+</style></keyword><keyword><style  face="normal" font="default" size="100%">GC-MS</style></keyword><keyword><style  face="normal" font="default" size="100%">MCF-7</style></keyword><keyword><style  face="normal" font="default" size="100%">MTT Assay</style></keyword><keyword><style  face="normal" font="default" size="100%">Phallus</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">699-708</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective: &lt;/strong&gt;Present study aims to evaluate the efficacy of methanolic and ethyl acetate extracts of wild mushroom &lt;em&gt;Phallus&lt;/em&gt; sp. on cell proliferation of both normal and cancer cells. This study also looked at anti-oxidant potentiality of methanolic extract and also unravels the phytochemical profiling of both extracts. &lt;strong&gt;Methods: &lt;/strong&gt;Anti-proliferative activity was assessed by MTT assay on different human cancer cell lines such as MCF-7, MOLT-4, REH and Peripheral Blood Mononuclear Cells or PBMC isolated from a healthy donor. Gas Chromatography-Mass Spectrometry (GC-MS) analysis was used for comparative assessment of phytochemical constituents of both extracts. The anti-oxidant profile of methanolic extract was also evaluated by DPPH and ABTS&lt;strong&gt;•+&lt;/strong&gt; assays. &lt;strong&gt;Results:&lt;/strong&gt; Results indicated that the both methanolic and ethyl acetate extracts of &lt;em&gt;Phallus&lt;/em&gt; sp. showed appreciable anti-proliferative activity against breast cancer cell line MCF-7 with IC&lt;sub&gt;50&lt;/sub&gt; of 8.544±2.812 μg/mL and 35.279±2.863 μg/mL respectively. Both of the extracts also showed its moderate impact on human B cell precursor leukemia cell line (REH) with IC&lt;sub&gt;50&lt;/sub&gt; of 25.987±2.696 μg/mL for methanol and 51.484±1.480 μg/mL for ethyl acetate extract respectively. No effect was observed in MOLT-4 cell line. Methanolic extract was selected as better anti cancer extract over ethyl acetate extract. No significant anti-proliferative activity was observed in normal PBMC by both extracts. GC-MS analysis indicated that 43 and 114 compounds were identified from methanolic and ethyl acetate extracts respectively. Among them nine compounds shared its existence in both of the extracts. Different derivatives of ergosterol and several fatty acid esters ware identified as major components from both of the extracts. Methanolic extracts of the &lt;em&gt;Phallus&lt;/em&gt; sp. showed its effectiveness on both of DPPH and ABTS&lt;strong&gt;•+ &lt;/strong&gt;free radical, and result indicated that it contain more flavonoid content than phenol. &lt;strong&gt;Conclusion:&lt;/strong&gt; The methanolic extract of &lt;em&gt;Phallus&lt;/em&gt; sp. show very specific anti-proliferative effect on MCF-7 with moderate anti-oxidant activity and holds a great promise for isolation of bio molecules for treating Breast Cancer. Several derivatives of ergosterol identified as probable anti-cancer compound.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">699</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ribhu Ray, Amrita Pal, Santanu Paul* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Laboratory of Cell and Molecular Biology, Department of Botany, University of Calcutta, Kolkata 700019, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Amrita Pal</style></author><author><style face="normal" font="default" size="100%">Anirban Chouni</style></author><author><style face="normal" font="default" size="100%">Arpan Das</style></author><author><style face="normal" font="default" size="100%">Ribhu Ray</style></author><author><style face="normal" font="default" size="100%">Santanu Paul</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Evaluation of Anti-proliferative Potential and Antioxidant Activity of a Wild Edible Mushroom Macrocybe crassa (Sacc.) Pegler and Lodge</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Macrocybe crassa</style></keyword><keyword><style  face="normal" font="default" size="100%">MCF7</style></keyword><keyword><style  face="normal" font="default" size="100%">MOLT-4</style></keyword><keyword><style  face="normal" font="default" size="100%">MTT Assay</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1504-1510</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; This study aims to quantify the anti-oxidant activity of the methanolic extract of &lt;em&gt;Macrocybe crassa &lt;/em&gt;and its anti-proliferative activity on normal and cancer cells. &lt;strong&gt;Methods:&lt;/strong&gt; The anti-oxidant potential of the extract was determined by several&lt;em&gt; in vitro&lt;/em&gt; assay system like DPPH radical scavenging activity, superoxide anion scavenging activity, percentage inhibition of lipid peroxidation and nitric oxide (NO) scavenging activity. Anti-proliferative activity was tested by MTT assay on breast cancer cell line MCF7, Human acute T lymphoblastic leukaemic cell MOLT-4 and Peripheral Blood Mononuclear Cells or PBMC isolated from a healthy donor to check its cytotoxic effect on normal cells. &lt;strong&gt;Results: &lt;/strong&gt;Results indicated that the methanolic extract of &lt;em&gt;Macrocybe crassa&lt;/em&gt; shows appreciable anti-proliferative activity against breast cancer cell line MCF7 and negligible effect on MOLT4 cells. In contrast no significant anti-proliferative effect has been observed in normal PMMCs. Moderate anti-oxidant activity was recorded in methanolic extract. &lt;strong&gt;Conclusion:&lt;/strong&gt; Methanolic extract of of &lt;em&gt;Macrocybe crassa&lt;/em&gt; with moderate anti-oxidant activity and specific anti-proliferative effect on MCF7 holds a great promise can be used for isolation of bio molecules for treating Breast Cancer.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1504</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Amrita Pal, Anirban Chouni, Arpan Das, Ribhu Ray, Santanu Paul* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Laboratory of Cell and Molecular Biology, Department of Botany, University of Calcutta, Kolkata 700019, INDIA.&lt;/p&gt;
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