<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Vera Ladeska</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Muhammad Hanafi</style></author><author><style face="normal" font="default" size="100%">Kusmardi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidants, Total Phenolic and Flavonoid Content and Toxicity Assay of Ampelas (Tetracera macrophylla Wall.Ex Hook.F.&amp; Thoms) From Kalimantan-Indonesia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidants</style></keyword><keyword><style  face="normal" font="default" size="100%">Tetracera macrophylla</style></keyword><keyword><style  face="normal" font="default" size="100%">total flavonoid</style></keyword><keyword><style  face="normal" font="default" size="100%">total phenolic</style></keyword><keyword><style  face="normal" font="default" size="100%">Toxicity</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">642-648</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background&lt;/strong&gt;: High Reactive Oxygen Species (ROS) contribute to disease pathogenesis. Phenolic compounds and flavonoids are effective as antioxidants. &lt;strong&gt;Objective: &lt;/strong&gt;This research aimed to measure the antioxidant activity, total phenolic and flavonoid content and leaf toxicity of&lt;em&gt; Tetracera macrophylla.&lt;/em&gt;&lt;strong&gt; Methods: &lt;/strong&gt;DPPH and FRAP were used to determine antioxidants, and the Folin–Ciocalteu method was used for total phenolic content, total flavonoid content with AlCl3 and toxicity with MTT assay against RAW 264.7 cells. &lt;strong&gt;Results:&lt;/strong&gt; Methanol extract has antioxidant activity with IC50 = 81.582 μg/mL (DPPH) and 11840 mol/g (FRAP), total phenolic content of 353.781 mg GAE/g dry weight, and flavonoid content of 279.2 mg QE/g dry weight. The ethyl acetate and n-hexane extracts had weaker antioxidant activity than the methanol extracts. The IC50 toxicity assay methanol extract and ethyl acetate extract respectively showed 288.792 μg/mL and 541.472 μg/mL.&lt;strong&gt; Conclusion&lt;/strong&gt;: The methanol extract of &lt;em&gt;Tetracera macrophylla&lt;/em&gt; showed the highest yield, total phenolic content and total flavonoid content and had the highest antioxidant activity. Methanol extract has low toxicity to RAW 264.7 cells.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">642-648</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Vera Ladeska&lt;sup&gt;1,2&lt;/sup&gt;, Berna Elya&lt;sup&gt;1,*&lt;/sup&gt;, Muhammad Hanafi&lt;sup&gt;3,4&lt;/sup&gt;, Kusmardi&lt;sup&gt;5&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, University of Indonesia, Depok, 16424, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy and Science Muhammadiyah Prof.Dr. Hamka,13460, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Research Center for Chemistry, Indonesian National Research and Innovation Institute, Serpong, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Pharmacognosy Phytochemistry, Faculty of Pharmacy University of Pancasila, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Anatomic Pathology, Faculty of Medicine, University of Indonesia, Jakarta, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rini Prastiwi</style></author><author><style face="normal" font="default" size="100%">Ema Dewanti</style></author><author><style face="normal" font="default" size="100%">Cut Mauliza</style></author><author><style face="normal" font="default" size="100%">Ester Hidayati</style></author><author><style face="normal" font="default" size="100%">Ita Anggraini</style></author><author><style face="normal" font="default" size="100%">Riska Anggraini</style></author><author><style face="normal" font="default" size="100%">Vera Ladeska</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Acute Toxicity of Ki Hampelas Leaves (Sterculia rubiginosa Zoll. Ex Miq)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acute toxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Ki Hampelas ( Sterculia rubiginosa Zoll. Ex Miq)</style></keyword><keyword><style  face="normal" font="default" size="100%">Kidney</style></keyword><keyword><style  face="normal" font="default" size="100%">Liver</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">570-576</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Ki Hampelas (&lt;em&gt;Sterculia rubiginosa&lt;/em&gt; Zoll. Ex Miq) is a medicinal plant with antioxidant and nephroprotective activity. &lt;strong&gt;Objective:&lt;/strong&gt; This research aims to prove that Ki Hampelas leaves extract through an acute toxicity test. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;This study used white male rats of the&lt;em&gt; Sprague-Dawley&lt;/em&gt; strain divided into four groups, the normal group and the 50 mg/ kg, 1000 mg/kg, 2000 mg/kg dose groups. For the acute toxicity test, a single dose with an observation of 14 days. After that, the surgery was done to see changes in the histopathology of the liver and kidneys. &lt;strong&gt;Results: &lt;/strong&gt;The administration of Ki Hampelas leaf extract in the acute toxicity test did not cause death in the tested animals. There were no significant liver and kidney changes seen from the SGOT, SGPT, creatinine, urea, and histopathology. &lt;strong&gt;Conclusion:&lt;/strong&gt; Ki Hampelas leaves extract did not cause death and toxic effects in the acute toxicity test.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">570</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Rini Prastiwi*, Ema Dewanti, Cut Mauliza, Ester Hidayati, Ita Anggraini, Riska Anggraini, Vera Ladeska&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;University of Mu- hammadiyah Prof. Dr. Hamka, Klender, Jakarta 13460, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rini Prastiwi</style></author><author><style face="normal" font="default" size="100%">Ema Dewanti</style></author><author><style face="normal" font="default" size="100%">Inka Nurul Fadliani</style></author><author><style face="normal" font="default" size="100%">Nessa Aqilla</style></author><author><style face="normal" font="default" size="100%">Salwaa Salsabila</style></author><author><style face="normal" font="default" size="100%">Vera Ladeska</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Nephroprotective And Antioxidant Activity of Sterculia rubiginosa Zoll. Ex Miq. Leaves</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Gentamicin</style></keyword><keyword><style  face="normal" font="default" size="100%">Nephroprotective</style></keyword><keyword><style  face="normal" font="default" size="100%">Sterculia rubiginosa Zoll Ex. Miq.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">843-849</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;Sterculia&lt;/em&gt; has an antioxidant activity. The &lt;em&gt;Sterculia &lt;/em&gt;genus has phenols and flavonoids content, and this chemical content may be have an nephroprotective activity. &lt;strong&gt;Objective: &lt;/strong&gt;The study was to investigate the &lt;em&gt;in vitro &lt;/em&gt;study of antioxidant activity with DPPH and FRAP study and nephroprotective activity of &lt;em&gt;Sterculia rubiginosa &lt;/em&gt;Zoll. Ex Miq. Leaves extract. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;The leaves was extracted using ethanol. This extract was determined for antioxidant activity by &lt;em&gt;in vitro &lt;/em&gt;study with DPPH and FRAP methods, determined the content of total phenols, total flavonoids, and also identification of chemical content. Nephrotoxicity study done by induced gentamycin. The groups divided 6 group, consist: negative control, positive control, normal control, and the extract with dose 50 mg/kg, 100 mg/kg, and 200 mg/ kg. The parameter for nephroprotective activity was tubular necrosis, the presence of tubules casts and glomerular damage, creatinine serum, and urea. &lt;strong&gt;Results:&lt;/strong&gt; The ethanol extract has IC&lt;sub&gt;50 &lt;/sub&gt;162.34 μg/ml for DPPH scavenging activity and 18.65 ± 3.53 FeEAC (Mol/g) for FRAP. The secondary metabolite presence flavonoids, tannins, terpenes, alkaloids, and glycosides. The total phenols 462.36 ± 9.23 mg GAE/gr, total flavonoids content 59.44 ± 0.11 mg QE/gr extract. All the dose have an nephroprotective activity, but the best dose was 50 mg/kg. &lt;strong&gt;Conclusion: &lt;/strong&gt;The ethanol extract of &lt;em&gt;Sterculia rubiginosa&lt;/em&gt; showed antioxidant activity and nephroprotective activity.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">843</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Rini Prastiwi&lt;sup&gt;1,&lt;/sup&gt;*, Ema Dewanti&lt;sup&gt;1&lt;/sup&gt;, Inka Nurul Fadliani&lt;sup&gt;2&lt;/sup&gt;, Nessa Aqilla&lt;sup&gt;2&lt;/sup&gt;, Salwaa Salsabila&lt;sup&gt;2&lt;/sup&gt;, Vera Ladeska&lt;sup&gt;1&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy Universitas Muhammadiyah prof. Dr. HAMKA, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacology, Faculty of Pharmacy Universitas Muhammadiyah prof. Dr. HAMKA, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Vera Ladeska</style></author><author><style face="normal" font="default" size="100%">Ema Dewanti</style></author><author><style face="normal" font="default" size="100%">Deviana Indah Sari</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pharmacognostical Studies and Determination of Total Flavonoids of Paitan (Tithonia diversifolia (Hemsl.) A. Gray</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Pharmacognostical</style></keyword><keyword><style  face="normal" font="default" size="100%">Physicochemical</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical</style></keyword><keyword><style  face="normal" font="default" size="100%">Tithonia diversifolia (Hemsl.) A. Gray)</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1256-1261</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;em&gt;Tithonia diversifolia &lt;/em&gt;(Hemsl.) A. Gray is one of the plants used in traditional medicine and belongs to Compositae family. In different parts of Indonesia, it is commonly known as “&lt;em&gt;paitan&lt;/em&gt; and &lt;em&gt;kembang bulan&lt;/em&gt;”. The study provides an early description of &lt;em&gt;Tithonia diversifolia&lt;/em&gt; (Hemsl.) A. Gray) and complete the monographs data extract. This plant prospects to the main source of the raw material for the herb-drug product and some parameters identified were needed to ensure the safety, quality and efficacy of the product. The present study is to evaluate macrosand microscopic characteristic of the Indonesian plant and its quality parameter including fluorescence, physicochemical characteristics and phytochemical screening. Moisture content, ethanol and water-soluble extract was determined, and were discovered to be 11,27%, 4,73% and 18,01%. Total ash value and acid insoluble ash value were determined which was 10.29 and 0.72 % respectively. Phytochemical screening of aqueous ethanol extract of &lt;em&gt;Tithonia diversifolia &lt;/em&gt;showed the presence of alkaloids, flavonoids, tannins, saponins and triterpenoids. The result showed that average content of flavonoid total is 69.1653 mg QE/g extract.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1256</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Vera Ladeska*, Ema Dewanti, Deviana Indah Sari&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Faculty of Pharmacy and Sciences, University of Muhammadiyah Prof. Dr.Hamka, Jakarta, INDONESIA.&lt;/p&gt;
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