<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Guseinov MD</style></author><author><style face="normal" font="default" size="100%">Bobkova NV</style></author><author><style face="normal" font="default" size="100%">Svistunov AA</style></author><author><style face="normal" font="default" size="100%">Tarasov VV</style></author><author><style face="normal" font="default" size="100%">Bokov DO</style></author><author><style face="normal" font="default" size="100%">Sergunova EV</style></author><author><style face="normal" font="default" size="100%">Kovaleva TYu</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Flavonoids in Passiflora incarnata L. Dry Extract of Russian Origin</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Dry extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoids</style></keyword><keyword><style  face="normal" font="default" size="100%">Passiflora incarnata</style></keyword><keyword><style  face="normal" font="default" size="100%">standardization</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1143-1147</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Flavonoids are one of the main classes of biologically active substances providing the pharmacotherapeutic effect of passionflower (&lt;em&gt;Passiflora incarnata&lt;/em&gt; L.) preparations. In this article studies on the standardization of &lt;em&gt;Passiflora incarnata&lt;/em&gt; L. dry extract (PDE) by flavonoids are presented. The aim of this work was to study the composition and content of flavonoids in PDE with the help of precise modern physicochemical methods. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; PDE was prepared from crude herbal drug – &lt;em&gt;P. incarnata&lt;/em&gt; herb of Russian origin. Reverse phase HPLC-UV analysis was performed with Agilent 1100 liquid chromatograph. Chromatographic column was Atlantis C&lt;sub&gt;18&lt;/sub&gt; (250 mm × 4.6 mm × 5 μm); analytical wavelength – 350 nm; mobile phase – 0.01% formic acid solution and methanol: acetonitrile (25:75); column temperature – 35°C; analysis time – 90 min; flow rate of the mobile phase – 0.8 ml/min in gradient elution mode. Commercially available samples of flavonoids were used for identification and quantitative determination. &lt;strong&gt;Results: &lt;/strong&gt;20 compounds of flavonoid structure are presented in the PDE. 9 flavonoid compounds have been identified, they are: isovitexin, vitexin, rutoside, hyperoside, luteolin, kaempferol, kaempferitrin, orientin, and isoorientin. The content of vitexin is 0,867 ± 0,011%, the total flavonoids content in terms of vitexin is 3,762 ± 0,049%. &lt;strong&gt;Conclusion: &lt;/strong&gt;The obtained data will be used to create regulatory documentation for drugs based on PDE.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1143</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Guseinov MD&lt;sup&gt;1&lt;/sup&gt;, Bobkova NV&lt;sup&gt;2&lt;/sup&gt;, Svistunov AA&lt;sup&gt;2&lt;/sup&gt;, Tarasov VV&lt;sup&gt;2&lt;/sup&gt;, Bokov DO&lt;sup&gt;2,3,&lt;/sup&gt;*, Sergunova EV&lt;sup&gt;2&lt;/sup&gt;, Kovaleva TYu&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Medical College named after Bashlarov, Amet Khan Sultan Ave., 10th km., 367915, Makhachkala, Republic of Dagestan, RUSSIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Sechenov First Moscow State Medical University, 8 Trubetskaya St., bldg. 2, 119991, RUSSIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Federal Research Center for Nutrition, Biotechnology and Food Safety, 2/14, Ustyinsky pr., Moscow, 109240, RUSSIA.&lt;/p&gt;
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