<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Twumasi Mary A</style></author><author><style face="normal" font="default" size="100%">Ekuadzi Edmund</style></author><author><style face="normal" font="default" size="100%">Mante Priscilla K</style></author><author><style face="normal" font="default" size="100%">Boakye-Gyasi Mariam E</style></author><author><style face="normal" font="default" size="100%">Mensah Merlin LK</style></author><author><style face="normal" font="default" size="100%">Woode Eric</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pharmacognostic Studies of the Leaves, Stem and Root of Capparis erythrocarpos Isert (Capparaceae)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Capers</style></keyword><keyword><style  face="normal" font="default" size="100%">Cicatrices</style></keyword><keyword><style  face="normal" font="default" size="100%">crystal sheaths</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbal medicine</style></keyword><keyword><style  face="normal" font="default" size="100%">Morphological features</style></keyword><keyword><style  face="normal" font="default" size="100%">Physicochemical parameters</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">112-118</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; The roots of &lt;em&gt;Capparis erythrocarpos&lt;/em&gt; are used traditionally across Africa for the management of pain, arthritis and other forms of inflammatory conditions. Owing to its proven efficacy, it has gained commercial value, particularly as a key ingredient in several herbal products and alcoholic beverages. The increased scarcity owing to demand outstripping supply lend the roots of &lt;em&gt;C. erythrocarpos&lt;/em&gt; to adulteration. This paper presents a detailed pharmacognostic evaluation of the leaf, stem and root of &lt;em&gt;C. erythrocarpos&lt;/em&gt; which will be used in its identification and consequent standardization. &lt;strong&gt;Methods:&lt;/strong&gt; The leaf, stem and root were evaluated for their macroscopic and microscopic features as were the physicochemical parameters and phytochemical screening done. &lt;strong&gt;Results:&lt;/strong&gt; Leaves are alternately arranged, have collateral vascular bundle, crystal sheaths and a pericyclic fibre. Actinocytic stomata and secretory cells were contained in powdered leaves. The stem showed lenticels and thorns, stellate and branched trichomes which leave off cicatrices in older stems. The powdered stem and roots contained stone cells, secretory cells and scalariform vessels. However, the roots lacked thorns, trichomes and had smaller secretory cells. Aqueous and ethanolic extracts of the leaves, stem and roots were slightly acidic to neutral. Ash values of leaves, stem and roots are (16.58 ± 0.09) % w/w, (5.01 ± 0.09) % w/w and (6.53 ± 0.19) % w/w respectively. Preliminary phytochemical screening of the leaves, stem and roots showed the presence of glycosides, flavonoids and tannins. &lt;strong&gt;Conclusion:&lt;/strong&gt; The determined parameters for the leaf, stem and root of &lt;em&gt;C. erythrocarpos&lt;/em&gt; constitute quality parameters for their unequivocal identification.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">112</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Twumasi Mary A&lt;sup&gt;1&lt;/sup&gt;, Ekuadzi Edmund&lt;sup&gt;1,*&lt;/sup&gt;, Mante Priscilla K&lt;sup&gt;2&lt;/sup&gt;, Boakye-Gyasi Mariam E&lt;sup&gt;3&lt;/sup&gt;, Mensah Merlin LK&lt;sup&gt;4&lt;/sup&gt;, Woode Eric&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, GHANA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, GHANA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, GHANA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Herbal Medicine, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, GHANA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ameyaw Elvis Ofori</style></author><author><style face="normal" font="default" size="100%">Boampong Johnson Nyarko</style></author></authors><secondary-authors><author><style face="normal" font="default" size="100%">Kyei Samuel</style></author></secondary-authors><tertiary-authors><author><style face="normal" font="default" size="100%">Woode Eric</style></author><author><style face="normal" font="default" size="100%">Biny Peter Robert</style></author></tertiary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Anti-Nociceptive Synergism of Pregabalin and Xylopic acid Co-administration in Paclitaxel-induced Neuropathy: Isobolographic Analysis</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Isobolograms</style></keyword><keyword><style  face="normal" font="default" size="100%">Neuropathic pain</style></keyword><keyword><style  face="normal" font="default" size="100%">Paclitaxel</style></keyword><keyword><style  face="normal" font="default" size="100%">Toxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">xylopic acid</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Nov-Dec 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">363-368</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">363</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ameyaw Elvis Ofori&lt;sup&gt;1*&lt;/sup&gt;, Woode Eric&lt;sup&gt;3&lt;/sup&gt;, Kyei Samuel&lt;sup&gt;2&lt;/sup&gt;, Biny Peter Robert&lt;sup&gt;3&lt;/sup&gt; and Boampong Johnson Nyarko&lt;sup&gt;1&lt;/sup&gt; &lt;/strong&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biomedical and Forensic Sciences, School of Biological Sciences, College of Agriculture and Natural Sciences, University of Cape Coast, Cape Coast, Ghana. 2Department of Optometry, School of Physical Sciences, College of Agriculture and Natural Sciences, University of Cape Coast, Cape Coast, Ghana. 3Department of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ameyaw Elvis Ofori</style></author><author><style face="normal" font="default" size="100%">Woode Eric</style></author><author><style face="normal" font="default" size="100%">Kyei Samuel</style></author><author><style face="normal" font="default" size="100%">Biny Peter Robert</style></author><author><style face="normal" font="default" size="100%">Boampong Johnson Nyarko</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anti-Nociceptive Synergism of Pregabalin and Xylopic acid Co-administration in Paclitaxel-induced Neuropathy: Isobolographic Analysis</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Isobolograms</style></keyword><keyword><style  face="normal" font="default" size="100%">Neuropathic pain</style></keyword><keyword><style  face="normal" font="default" size="100%">Paclitaxel</style></keyword><keyword><style  face="normal" font="default" size="100%">Toxicity.</style></keyword><keyword><style  face="normal" font="default" size="100%">xylopic acid</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">7th July 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">55-57</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Paclitaxel-induced neuropathy still remains a clinical problem for patients undergoing chemotherapy. &lt;strong&gt;Objective: &lt;/strong&gt;The objective of the study was to determine the interaction between xylopic acid and pregabalinco-administration as well as their toxicity in paclitaxel-induced neuropathy. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;Neuropathic pain was induced in rats with 2 mg/kg of paclitaxel on alternative days for four days (days 0, 2, 4 and 6). Equi effective doses of xylopic acid and pregabalin that produced 50% anti-nociception (ED50) were determined from their log-dose response curves in the cold allodynia and thermal pain tests. Xylopic acid and pregabalin were again administered to rats in a fixed ratio combination (1:1) of their ED50&amp;rsquo;sin order to determine the experimental ED50 (Zexp) of the co-administered compounds. Isobolograms were constructed to compare the Zexp to a theoretical ED50 (Zadd). Blood samples from the various treatment groups of rats were collected for toxicological assessment of the co-administered compounds. &lt;strong&gt;Results:&lt;/strong&gt; The Zexplay below the Zadd on the isobologram of the cold allodnia test. The co-administration exhibited additivity in the thermal pain test. The co-administration did not produce significant (p&amp;gt;0.05) toxicity in rats. The co-administration may be beneficial in paclitaxel-induced neuropathy.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words:&lt;/strong&gt; Isobolograms, Neuropathic pain, Paclitaxel, xylopic acid, Toxicity.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ameyaw Elvis Ofori&lt;sup&gt;1*&lt;/sup&gt;, Woode Eric&lt;sup&gt;3&lt;/sup&gt;, Kyei Samuel&lt;sup&gt;2&lt;/sup&gt;, Biny Peter Robert&lt;sup&gt;3&lt;/sup&gt;, Boampong Johnson Nyarko&lt;sup&gt;1 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biomedical and Forensic Sciences, School of Biological Sciences, College of Agriculture and Natural Sciences, University of Cape Coast, Cape Coast, Ghana.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Optometry, School of Physical Sciences, College of Agriculture and Natural Sciences, University of Cape Coast, Cape Coast, Ghana.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.&lt;/p&gt;</style></auth-address></record></records></xml>