<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Tchaa Kozolina</style></author><author><style face="normal" font="default" size="100%">Poyodi Kola</style></author><author><style face="normal" font="default" size="100%">Diana Obistioiu</style></author><author><style face="normal" font="default" size="100%">Doris Floares</style></author><author><style face="normal" font="default" size="100%">Aboudoulatif Diallo</style></author><author><style face="normal" font="default" size="100%">Batomayena Bakoma</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Polyphenolic Characterization of Aqueous Extract and Comparative Antioxidant and Antibiofilm activities of Xylopia aethiopica Fruit Aqueous and Essential Oil Extracts against Candida Biofilms</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibiofilm</style></keyword><keyword><style  face="normal" font="default" size="100%">crystal violet</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC-DAD</style></keyword><keyword><style  face="normal" font="default" size="100%">individual polyphenols</style></keyword><keyword><style  face="normal" font="default" size="100%">Xylopia aethiopica</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2026</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2026</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">18</style></volume><pages><style face="normal" font="default" size="100%">358-366</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;The increasing resistance of &lt;em&gt;Candida &lt;/em&gt;species to conventional antifungals necessitates the search for new bioactive compounds. &lt;em&gt;Xylopia aethiopica&lt;/em&gt; is a medicinal plant known for its antifungal properties, yet its impact on fungal biofilms remains to be explored. This study characterized the polyphenolic profile of &lt;em&gt;Xylopia aethiopica&lt;/em&gt; hydroethanolic fruit extract and compared the antibiofilm activity of its aqueous extracts and essential oils against &lt;em&gt;Candida &lt;/em&gt;biofilms. &lt;strong&gt;Methodes: &lt;/strong&gt;Total phenols and flavonoids were quantified, and individual compounds were identified via HPLC-DAD. The antioxidant capacity was evaluated by DPPH (2,2-diphenyl-1-pyrylhydrazyl) test. The antibiofilm potential was evaluated using the crystal violet assay to measure biomass reduction and assess the impact on the yeast-tohypha transition. &lt;strong&gt;Results: &lt;/strong&gt;Analyses revealed a rich profile characterized by high yields of epicatechin, phenolic acids, rosmarinic acid, and resveratrol, which impart significant antioxidant properties. In vitro assays demonstrated that among the aqueous extracts, only the hydromethanolic extract (1:2) inhibited biofilms. Conversely, the essential oils exhibited strong dose-dependent efficacy, with hydrodistillation proving superior to steam distillation in restricting the biofilm growth of&lt;em&gt; C. albicans&lt;/em&gt; and &lt;em&gt;C. parapsilosis&lt;/em&gt;. &lt;strong&gt;Conclusion: &lt;/strong&gt;These findings suggest that &lt;em&gt;Xylopia aethiopica&lt;/em&gt; is a potent source of antibiofilm agents. The essential oil obtained by hydrodistillation represents a promising alternative for eradicating resistant &lt;em&gt;Candida &lt;/em&gt;communities, highlighting the crucial impact of the extraction method on bioactivity.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">358</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Tchaa Kozolina&lt;sup&gt;1,3,5*&lt;/sup&gt;, Poyodi Kola&lt;sup&gt;2&lt;/sup&gt;, Diana Obistioiu&lt;sup&gt;3&lt;/sup&gt;, Doris Floares&lt;sup&gt;3&lt;/sup&gt;, Aboudoulatif Diallo&lt;sup&gt;4&lt;/sup&gt;, Batomayena Bakoma&lt;sup&gt;5&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Laboratory of pharmaceutical sciences, Faculty of health sciences, Doctoral school ED732-STIS, University of Lome, 01 BP: 1515, Lome, TOGO.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratory of applied agronomic and biological sciences (LaSABA), Faculty of sciences and techniques, University of Kara, BP: 404, Kara, TOGO.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Interdisciplinary research platform, University of life sciences “King Michael I” from Timisoara, Calea Aradului 119, 300645 Timisoara, ROMANIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of pharmacy, Laboratory of pharmacology-toxicology, Faculty of health sciences, University of Lomé, BP: 1515, Lome, TOGO.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of pharmacy, Laboratory of pharmaceutical sciences, Faculty of health sciences, University of Lomé, BP: 1515, Lome, TOGO.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sabrina Chris Janiba Sanvee</style></author><author><style face="normal" font="default" size="100%">Bignoate Kombate</style></author><author><style face="normal" font="default" size="100%">Yendubé Toughelighan Kantati</style></author><author><style face="normal" font="default" size="100%">Pascaline Kindji Kpoyizoun</style></author><author><style face="normal" font="default" size="100%">Essotolom Badjabaissi</style></author><author><style face="normal" font="default" size="100%">Mindede Assih1 Aboudoulatif Diallo</style></author><author><style face="normal" font="default" size="100%">Batomayena Bakoma</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Phytochemistry, Antihyperglycemic, Antioxidant and Anti- Inflammatory Properties of Uvaria Chamae and Sida Linifolia Extracts: Potential Implication in Diabetic Disease</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Decoction</style></keyword><keyword><style  face="normal" font="default" size="100%">hyperglycemia</style></keyword><keyword><style  face="normal" font="default" size="100%">Neuroprotection</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemistry</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">582-590</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Uvaria chamae and Sida linifolia are plants traditionally used in Togo in diabetes treatment, an affection that often leads to several complications. This study aimed to evaluate the antihyperglycemic, anti-inflammatory, antioxidant activity and toxicity of these two plants extracts.&lt;strong&gt; Methods:&lt;/strong&gt; A phytochemical analysis was carried out on extracts obtained either by decoction or maceration in ethanol of Uvaria chamae leaves and Sida linifolia whole plant. Evaluation of the antihyperglycemic activity consisted in glucose absorption test using yeast and rats’ muscle and jejunum. DPPH test, total antioxidant capacity assay, hemolysis and egg albumin denaturation inhibition assays and evaluation of extracts acute toxicity were performed. &lt;strong&gt;Results: &lt;/strong&gt;Hydroalcoholic extract of Uvaria chamae showed the strongest antihyperglycemic activity (p&amp;lt;0.05); the highest phenolic contents (147.93 ± 1.01 mg/g), the best total antioxidant capacity (153.33 ± 4.07), the lowest IC50 (μg/mL) for DPPH test (296.96 ± 91.69), a capacity of hemolysis (825.99 ± 29.24) and egg albumin denaturation (738.10 ± 92.26) inhibition assays. In the same way, hydroalcoholic extract of Sida linifolia, showed the strongest antihyperglycemic activity (p&amp;lt;0.05), the highest phenolic contents (71.60 ± 2.16 mg/g), the best total antioxidant capacity (146.98 ± 2.81), lowest IC50 (μg/ mL) for DPPH test (788.28 ± 112.54), the hemolysis (882.03 ± 20.86) and egg albumin denaturation (1966.18 ± 35.94) inhibition assays. None of the extracts showed acute toxicity in rats. &lt;strong&gt;Conclusion: &lt;/strong&gt;the hydroalcoholic leaves extract of Uvaria chamae and of the whole plant of Sida linifolia could be candidates in the treatment of diabetes and its complications.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">582-590</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Sabrina Chris Janiba Sanvee&lt;sup&gt;1&lt;/sup&gt;*, Bignoate Kombate², Yendubé Toughelighan Kantati², Pascaline Kindji Kpoyizoun², Essotolom Badjabaissi&lt;sup&gt;1&lt;/sup&gt;, Mindede Assih&lt;sup&gt;1&lt;/sup&gt; Aboudoulatif Diallo&lt;sup&gt;1&lt;/sup&gt; Batomayena Bakoma&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Laboratory of Pharmaceutical Science, Faculty of Health Sciences, University of Lomé, Lomé- Togo, 01BP 1515, LOME.&lt;/p&gt;

&lt;p&gt;²Laboratory of Physiology/Pharmacology, Physiopathology Bioactive Substances and Innocuity Research Unit (PBSI), Faculty of Sciences, University of Lomé, Lomé - Togo, 01BP 1515. LOME.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Messan Koffi Adjogblé</style></author><author><style face="normal" font="default" size="100%">Batomayena Bakoma</style></author><author><style face="normal" font="default" size="100%">Kossi Metowogo</style></author><author><style face="normal" font="default" size="100%">Kodjovi Dotsè Amouzou</style></author><author><style face="normal" font="default" size="100%">Yao Potchoo</style></author><author><style face="normal" font="default" size="100%">Kwashie Eklu-gadegbeku</style></author><author><style face="normal" font="default" size="100%">Kodjo A Aklikokou</style></author><author><style face="normal" font="default" size="100%">Menssanvi Gbeassor</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pharmacognostic Studies and Artemisinin Content of Artemisia Annua L. Grown in Togo</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Artemisia</style></keyword><keyword><style  face="normal" font="default" size="100%">Artemisinin</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoid</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacognostic</style></keyword><keyword><style  face="normal" font="default" size="100%">Total Phenols</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1331-1335</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective: &lt;/strong&gt;&lt;em&gt;Artemisia annua &lt;/em&gt;grown in Togo is used as an antimalaria drug. The present study shows a detailed analysis of pharmacognostic evaluation of leaf powder and root that will be used for the purpose of identification, authentication, and consequent standardization. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;Both the leaf and root were evaluated for their macroscopic and microscopic features. The physicochemical parameters of the leaf powder and its phytochemical screening were done based on its total phenols and flavonoïd content. Artemisinin content was also performed using weigh method after extraction. &lt;strong&gt;Results:&lt;/strong&gt; Physicochemical evaluation yielded water, alcohol, acetone, methanol, chloroform, and petroleum ether soluble extractive values which are 2.25%, 1.25%, 4.22%, 8.12% and 3.77% (w/w), respectively. Fluorescence analysis imparted characteristic colors to the leaf powder when observed under visible, UV light 254 and 365 nm. Phytochemical screening of leaf powder showed the presence of alkaloïds, flavonoïd, and anthracene derivatives. Total phenols and flavonoïd content were 32.5 ± 0.67 mEq Gallic Acid/100 mg and 11.3 ± 1.52. mgEq Quercetin/100 mg, respectively. Artemisinin content value was 0.009% (w/w). &lt;strong&gt;Conclusion:&lt;/strong&gt; Various pharmacognostic parameters which were evaluated assisted in identification and standardization of &lt;em&gt;A. annua &lt;/em&gt;leaf in powder and crude form.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1331</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Messan Koffi Adjogblé&lt;sup&gt;1&lt;/sup&gt;, Batomayena Bakoma&lt;sup&gt;1&lt;/sup&gt;,*, Kossi Metowogo&lt;sup&gt;2&lt;/sup&gt;, David Amouzou&lt;sup&gt;3&lt;/sup&gt;, Yao Potchoo&lt;sup&gt;1&lt;/sup&gt;, Kwashie Eklu-gadegbeku&lt;sup&gt;2&lt;/sup&gt;, Kodjo A. Aklikokou&lt;sup&gt;2&lt;/sup&gt;, Menssanvi Gbeassor&lt;sup&gt;2&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Health Sciences, University of Lomé, Po Box: 1515 Lomé, TOGO.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratory of Physiology/Pharmacology, Faculty of Sciences, University of Lomé, Po Box: 1515 Lomé, TOGO.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;House of Artemisia Biodélice, Achanvé Tsévié, TOGO.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Batomayena Bakoma</style></author><author><style face="normal" font="default" size="100%">Sabrina Sanvee</style></author><author><style face="normal" font="default" size="100%">Kossi Metowogo</style></author><author><style face="normal" font="default" size="100%">Yao Potchoo</style></author><author><style face="normal" font="default" size="100%">Kwashie Eklu gadegbeku</style></author><author><style face="normal" font="default" size="100%">Kodjo Aklikokou</style></author><author><style face="normal" font="default" size="100%">Menssanvi Gbeassor</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Phytochemical Study and Biological Activities of Hydro-Alcoholic Extract of the Leaves of Bridelia ferruginea Benth and its Fractions</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Bridelia ferruginea</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetes</style></keyword><keyword><style  face="normal" font="default" size="100%">Fractionation</style></keyword><keyword><style  face="normal" font="default" size="100%">OGTT</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">141-145</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Context and purpose:&lt;/strong&gt; The roots of &lt;em&gt;B. ferruginea&lt;/em&gt; are used in traditional Togo medicine in the treatment of diabetes. Studies have shown that leaves have a low antihyperglycemic effect. This study aims to improve the effect of leaves. &lt;strong&gt;Methods:&lt;/strong&gt; The hydroalcoholic extract of the leaves underwent a fractionation (separation in cold alcohol) and an OGTT (Oral Glucose tolerance test) on healthy mice, a phytochemical screening and antioxidant tests (&lt;em&gt;in vitro&lt;/em&gt;: DPPH and &lt;em&gt;ex vivo&lt;/em&gt;: AAPH) were performed on the extract and its fractions. &lt;strong&gt;Results:&lt;/strong&gt; Phytochemical screening of the extract showed the presence of phenols, flavonoids and condensed tannins as well as the absence of condensed tannins, alkaloids, saponosides and anthracene derivatives. The extract also showed antioxidant activity. The supernatant fraction showed antihyperglycemic activity at 100 mg / kg in the 30th and 60th after glucose administration. Phytochemical screening of the supernatant revealed the presence of phenols, flavonoids and condensed tannins. The supernatant also showed more pronounced antioxidant activity than the total extract. &lt;strong&gt;Conclusion:&lt;/strong&gt; In view of these results, the most active fraction obtained by the separation technique in cold alcohol is the supernatant.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">141</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Batomayena Bakoma&lt;sup&gt;1,*&lt;/sup&gt;, Sabrina Sanvee&lt;sup&gt;1&lt;/sup&gt;, Kossi Metowogo&lt;sup&gt;2&lt;/sup&gt;, Yao Potchoo&lt;sup&gt;1&lt;/sup&gt;, Kwashie Eklu gadegbeku&lt;sup&gt;2&lt;/sup&gt;, Kodjo Aklikokou&lt;sup&gt;2&lt;/sup&gt;, Menssanvi Gbeassor&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Health Sciences, University of Lomé, Po Box: 1515 Lomé, TOGO.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratory of Physiology/ Pharmacology, Faculty of Sciences, University of Lomé, Po Box: 1515 Lomé, TOGO.&lt;/p&gt;
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