<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Melakhessou Mohamed Akram</style></author><author><style face="normal" font="default" size="100%">Benkiki Naima</style></author><author><style face="normal" font="default" size="100%">Marref Salah Eddine</style></author><author><style face="normal" font="default" size="100%">Bouzidi Soumia</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anti-Inflammatory, Anti-pyretic and Acute Toxicity Effects of n-Butanol Extract of Atractylis flava Desf in Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Atractylis flava desf</style></keyword><keyword><style  face="normal" font="default" size="100%">Brewer’s yeast</style></keyword><keyword><style  face="normal" font="default" size="100%">Egg albumin</style></keyword><keyword><style  face="normal" font="default" size="100%">Inflammation</style></keyword><keyword><style  face="normal" font="default" size="100%">Pyrexia</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/666</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">763-767</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objectives:&lt;/strong&gt; This study was aimed to explore the antipyretic and anti-inflammatory effects of &lt;em&gt;n&lt;/em&gt;-butanol etract of &lt;em&gt;Atractylis flava &lt;/em&gt;Desf &lt;em&gt;(A. Flava)&lt;/em&gt; using experimentally induced inflammation and pyrexia models in rats. &lt;strong&gt;Methods:&lt;/strong&gt; In the acute toxicity study, a single oral dose of 2000 mg/kg of&lt;em&gt; n&lt;/em&gt;-butanol extract was given to rats. The antipyretic activity was evaluated using brewer&amp;rsquo;s yeast induced pyrexia in rats. In addition, albumin induced rat paw edema was performed by the injection of 100 &amp;mu;L undiluted fresh egg albumin to assess the anti-inflammatory effects of the plant. &lt;strong&gt;Results:&lt;/strong&gt; The results of the present study revealed that&lt;em&gt; n&lt;/em&gt;-butanol extract of &lt;em&gt;A. Flava&lt;/em&gt; significantly (&lt;em&gt;P&lt;/em&gt;&amp;lt;0.001) reduced fresh egg albumin-induced rat paw edema and also inhibited fever significantly in brewer&amp;rsquo;s yeast induced pyrexia. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results of the present study indicated that &lt;em&gt;A. flava&lt;/em&gt; possesses antipyretic and anti-inflammatory activity in the models studied.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">763</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Melakhessou Mohamed Akram*, Benkiki Naima, Marref Salah Eddine, Bouzidi Soumia &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Laboratoire de Biotechnologie des Mol&amp;eacute;cules Bioactives et de la Physiopathologie Cellulaire. Universit&amp;eacute; de Batna-2, 05000, ALGERIE.&lt;/p&gt;</style></auth-address></record></records></xml>