<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Neneng Siti Silfi Ambarwati</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Yesi Desmiaty</style></author><author><style face="normal" font="default" size="100%">Ayun Erwina Arifianti</style></author><author><style face="normal" font="default" size="100%">Islamudin Ahmad</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Tyrosinase Inhibitory Activity of Garcinia latissima Miq. Extracts</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Garcinia latissima Miq.</style></keyword><keyword><style  face="normal" font="default" size="100%">Succesive maceration</style></keyword><keyword><style  face="normal" font="default" size="100%">Tyrosinase</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1673-1677</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Tyrosinase is an enzyme that plays an essential part in the process of melanin synthesis. High exposure to ultraviolet (UV) radiation or high stimulation of melanocytes could cause excessive melanin pigments to lead to hyperpigmentation. &lt;strong&gt;Objective: &lt;/strong&gt;This study aimed to find potential natural skin lightening ingredients from &lt;em&gt;Garcinia latissima &lt;/em&gt;Miq. &lt;strong&gt;Methods:&lt;/strong&gt; Stem bark, fruits, and leaves of &lt;em&gt;Garcinia latissima&lt;/em&gt; Miq. were extracted with successive maceration. The tyrosinase inhibitory activity test was measured spectrophotometrically at 490 nm using 3,4-dihydroxy-L-phenylalanine (L-DOPA) as substrate and kojic acid as a positive control. &lt;strong&gt;Results:&lt;/strong&gt; The tyrosinase inhibitory activity test at a concentration of 100 ppm showed that the bark ethyl acetate extract 15.94% ± 7.70, bark methanol extract of 28.94% ± 5.73, fruit n-hexane extract 25.16% ± 10.22, fruit methanol extract 23.26% ± 9.10; and leaf methanol extract 30.59% ± 0.63 with kojic acid inhibition 65.07%. &lt;strong&gt;Conclusion:&lt;/strong&gt; Methanol extract of leaf from Garcinia latissima Miq was the most active extract as a tyrosinase inhibitor.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1673</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Neneng Siti Silfi Ambarwati&lt;sup&gt;1,&lt;/sup&gt;*, Berna Elya&lt;sup&gt;2&lt;/sup&gt;, Yesi Desmiaty&lt;sup&gt;3&lt;/sup&gt;, Ayun Erwina Arifianti&lt;sup&gt;4&lt;/sup&gt;, Islamudin Ahmad&lt;sup&gt;5&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Cosmetology Department, Faculty of Engineering, Universitas Negeri Jakarta, Jl. Rawamangun Muka, East Jakarta, Jakarta 13220, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratory of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok, West Java 16424, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Laboratory of Pharmacognosy, Faculty of Pharmacy, Universitas Pancasila, Jl. Srengseng Sawah, Jagakarsa, South Jakarta, Jakarta 12640, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Laboratory of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Indonesia, Depok, West Java 16424, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Mulawarman, Samarinda, East Kalimantan, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yesi Desmiaty</style></author><author><style face="normal" font="default" size="100%">Fadlina Chany Saputri</style></author><author><style face="normal" font="default" size="100%">Muhammad Hanafi</style></author><author><style face="normal" font="default" size="100%">Rini Prastiwi</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anti-Elastase, Anti-Tyrosinase and Anti-Oxidant of Rubus Fraxinifolius Stem Methanolic Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-Elastase</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-tyrosinase</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Rubus fraxinifolius stem</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">271-275</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Some Rubus were reported had anti-skin aging activity. &lt;em&gt;Rubus fraxinifolius &lt;/em&gt;was one of Rubus genus which lives in Indonesian highland.&lt;strong&gt; Objective: &lt;/strong&gt;This study was to examine elastase, tyrosinase, and oxidant inhibitory activity of &lt;em&gt;R. fraxinifolius &lt;/em&gt;stem (RFS) extract. &lt;strong&gt;Methods: &lt;/strong&gt;Extraction was done by a Soxhlet apparatus using methanol as solvent. Elastase inhibition activity was determined, which based on the formation of p-nitroaniline. Tyrosinase inhibition activity evaluated based on inhibition of mushroom tyrosinase by the sample with L-DOPA as substrate. The activity of antioxidant was determined using the DPPH radical scavenger method. LC-MS was used for prediction of naturally occurring phytochemicals. &lt;strong&gt;Results: &lt;/strong&gt;The RFS extract yield was 9.03 %. The RFS extract revealed inhibition activity against elastase and tyrosinase with IC&lt;sub&gt;50&lt;/sub&gt; 128.85 ppm, and 155.19 ppm, respectively. DPPH radical scavenging activity gave IC&lt;sub&gt;50&lt;/sub&gt; 63.04 ppm. Total phenolic content of the extract was 387.99+3.21 mg GAE/g extract. The LC-MS analysis showed the presence of at least 13 different organic compounds in RFS extract, which might contribute to the bioactivity. &lt;strong&gt;Conclusion: &lt;/strong&gt;Therefore, this experiment further proved that RFS extract might be useful as a natural product ingredient of anti-photoaging skincare products because of its ability to inhibit elastase, tyrosinase, and as an antioxidant.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">271</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Yesi Desmiaty&lt;sup&gt;1,2&lt;/sup&gt;, Fadlina Chany Saputri&lt;sup&gt;1&lt;/sup&gt;, Muhammad Hanafi&lt;sup&gt;2,3&lt;/sup&gt;, Rini Prastiwi&lt;sup&gt;4&lt;/sup&gt;, Berna Elya&lt;sup&gt;1,&lt;/sup&gt;*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Pharmacy, Pancasila Univercity, Jakarta, 12640, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Chemistry Research Centre, Indonesian Institute of Sciences (LIPI), PUSPIPTEK Serpong, 15314, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Faculty of Pharmacy, Universitas Muhammadiyah Prof. Dr Hamka, Jakarta, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rini Prastiwi</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Muhammad Hanafi</style></author><author><style face="normal" font="default" size="100%">Yesi Desmiaty</style></author><author><style face="normal" font="default" size="100%">Rani Sauriasari</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Antioxidant Activity of Sterculia stipulata Korth Woods and Leaves by FRAP Method</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoids</style></keyword><keyword><style  face="normal" font="default" size="100%">FRAP</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenols</style></keyword><keyword><style  face="normal" font="default" size="100%">Sterculia stipulata Korth</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">236-239</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Phenol compounds and flavonoids are known have antioxidant activity. &lt;em&gt;Sterculia &lt;/em&gt;genus has secondary metabolite rich of phenols and flavonoids. &lt;strong&gt;Objective: &lt;/strong&gt;The aim of this study of the activity antioxidants of &lt;em&gt;Sterculia stipulata&lt;/em&gt; Korth. Woods and leaves by FRAP method. &lt;strong&gt;Materials and methods:&lt;/strong&gt; Extraction done using n-hexane, ethyl acetate, and methanol. The methanol extract was determined antioxidant activity using the FRAP method and also determined the total phenols content, total flavonoids, and phytochemical screening. &lt;strong&gt;Results:&lt;/strong&gt; The antioxidant activity of wood extract was 4.74 ± 1.03 FeEAC (mol/g) while leaves extract 41.17 ± 1.99 FeEAC (mol/g). Total phenols content for wood extract 16.46 ± 3.51 mg GAE/g, for leaves extract 141.62 ± 10.54 mg GAE/g. The total flavonoids content for woods extract was 27.99 ± 0.62 mg QE/g for leaf extract 41.45 ± 5.83 mg QE/g. The compounds of woods and leaves are the same; it is consist of terpenoids, alkaloids, phenols, flavonoids, saponins, terpenoids, and negatives for anthraquinone. &lt;strong&gt;Conclusion: &lt;/strong&gt;The antioxidant activity of the leaves of &lt;em&gt;Sterculia stipulata&lt;/em&gt; Korth. is greater than its wood activities.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">236</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Rini Prastiwi&lt;sup&gt;1,2&lt;/sup&gt;, Berna Elya&lt;sup&gt;1,&lt;/sup&gt;*, Muhammad Hanafi&lt;sup&gt;3,4&lt;/sup&gt;, Yesi Desmiaty&lt;sup&gt;2&lt;/sup&gt;, Rani Sauriasari&lt;sup&gt;5&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy Universitas Indonesia, Depok 16424, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy and Science Muhammadiyah Prof. Dr. Hamka University, 1340 Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Research Center for Chemistry, Indonesian Institute of Science, Serpong (LIPI Indonesia), INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Pharmacognosy Phytochemistry, Faculty of Pharmacy Universitas Pancasila, Jakarta, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Pharmacology, Faculty of Pharmacy Indonesia University, Depok 16424, West Java, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rini Prastiwi</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Rani Sauriasari</style></author><author><style face="normal" font="default" size="100%">Muhammad Hanafi</style></author><author><style face="normal" font="default" size="100%">Yesi Desmiaty</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Arginase Inhibitory, Antioxidant Activity and Pharmacognosy Study of Sterculia macrophylla Vent. Leaves</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Arginase</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoid</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacognostical</style></keyword><keyword><style  face="normal" font="default" size="100%">Sterculia macrophylla</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">1109-1113</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The purpose of this study was to investigate the arginase inhibitory activity, antioxidant activity, and also pharmacognostical study of &lt;em&gt;Sterculia macrophylla&lt;/em&gt; leaves. The main component of genus &lt;em&gt;Sterculia&lt;/em&gt; was flavonoid that was well known to demonstrate arginase inhibitory activity. &lt;strong&gt;Methods:&lt;/strong&gt; Sample was extracted gradually using n-hexane, ethyl acetate, and methanol solvents, subsequently. The n-hexane, ethyl acetate, and methanol extract were determined for their arginase inhibitory activity. The most active extract was methanol extract. This extract was determined for its antioxidant activity, arginase inhibitory activity, identification of chemical compound, chromatogram profile and determined the content of total flavonoid. The leaves and powder of &lt;em&gt;Sterculia macrophylla&lt;/em&gt; were identified with microscopic and macroscopic evaluation. &lt;strong&gt;Results:&lt;/strong&gt; The most active extract was methanol extract with IC&lt;sub&gt;50&lt;/sub&gt; 114,659 &amp;mu;g/mL for arginase inhibitory activity and IC&lt;sub&gt;50&lt;/sub&gt; 78.47 &amp;mu;g/mL for DPPH scavenging activity. The secondary metabolite of methanol extract presence compound of alkaloid, flavonoid, tannin, terpene, and glycoside. The total flavonoid content was 141.10 mg/gram extract. The star-shape trichoma was identified as a specific fragment. &lt;strong&gt;Conclusion:&lt;/strong&gt; The methanol extract of &lt;em&gt;Sterculia macrophylla&lt;/em&gt; showed activity as arginase inhibitor and antioxidant.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1109</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Rini Prastiwi&lt;sup&gt;1,2&lt;/sup&gt;, Berna Elya&lt;sup&gt;1,&lt;/sup&gt;*, Rani Sauriasari&lt;sup&gt;3&lt;/sup&gt;, Muhammad Hanafi&lt;sup&gt;4&lt;/sup&gt;, Yesi Desmiaty&lt;sup&gt;5&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacognosy- Phytochemistry, Faculty of Pharmacy Universities Indonesia, Depok 16424, West Java, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy- Phytochemistry, Faculty of Pharmacy and Science Muhammadiyah Prof. Dr. Hamka University, 1340 Jakarta, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmacology, Faculty of Pharmacy Indonesia University, Depok 16424, West Java, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Research Center for Chemistry, Indonesian Institute of Science, Serpong (LIPI) INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Pharmacognosy- Phytochemistry, Faculty of Pharmacy Universitas Pancasila, Depok, West Java, INDONESIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ni Made Dwi Sandhiutami</style></author><author><style face="normal" font="default" size="100%">Yesi Desmiaty</style></author><author><style face="normal" font="default" size="100%">Noviyanti</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Inhibitory Effect of Lantana camara L., Eclipta prostrata (L.) L. and Cosmos caudatus Kunth. Leaf Extracts on ADP-Induced Platelet Aggregation</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-platelet aggregation</style></keyword><keyword><style  face="normal" font="default" size="100%">Cosmos caudatus kunth</style></keyword><keyword><style  face="normal" font="default" size="100%">Eclipta prostrata (L.) L.</style></keyword><keyword><style  face="normal" font="default" size="100%">Lantana camara L.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/528</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">581-585</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The leaves of &lt;em&gt;Lantana camara&lt;/em&gt; L., &lt;em&gt;Eclipta prostrata&lt;/em&gt; (L.) L. and &lt;em&gt;Cosmos caudatus&lt;/em&gt; Kunth. are rich in flavonoids, saponins and essential oils. This study was carried out to determine the antiplatelet effect of the three plant extracts on ADP-induced platelet aggregation. &lt;strong&gt;Methods:&lt;/strong&gt; The samples consisted of clopidogrel as positive control, aquadest as negative control and test extracts with concentrations of 40, 60, 80 and 100 mg/ml. Platelet Rich Plasma (PRP) was added for each extract concentration. The absorbance test of the samples was measured at 600 nm, before and after the addition of 20 &amp;mu;L adenosine diphosphate (ADP) 5 mM. After ADP added, then measured again the plasma absorbance was measured of the same wavelength. Antiplatelet aggregation activity was determined by calculating plasma absorbance before and after addition of ADP. &lt;strong&gt;Results:&lt;/strong&gt; The results showed that the inhibitory percentage of platelet aggregation with extract concentrations of 100, 80, 60 and 40 mg/ml were &lt;em&gt;Lantana camara&lt;/em&gt; L. leaf extract (91.17%; 73.27%; 72.86% and 37.15%), &lt;em&gt;Eclipta prostrata&lt;/em&gt; (L.) L. leaf extract (74.55%; 65.60%; 48.00% dan 39.08%) and &lt;em&gt;Cosmos caudatus&lt;/em&gt; Kunth. Leaf extract (59.17%; 52.56%; 14.25% dan 13.82%), respectively. The test extracts inhibited in vitro ADP-induced platelet aggregation with IC&lt;sub&gt;50&lt;/sub&gt; value were as follows: 47.09 mg/ml (&lt;em&gt;Lantana camara&lt;/em&gt; L), 59.02 mg/ml (&lt;em&gt;Eclipta prostrata&lt;/em&gt; (L.) L.) and 87.26 mg/ml (&lt;em&gt;Cosmos caudatus&lt;/em&gt; Kunth.) &lt;strong&gt;Conclusion:&lt;/strong&gt; The present work demonstrated that the three extracts could inhibit in-vitro ADP-induced platelet aggregation and the best potency was shown by &lt;em&gt;Lantana camara&lt;/em&gt; L leaf extract. </style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">581</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ni Made Dwi Sandhiutami&lt;sup&gt;*&lt;/sup&gt;, Yesi Desmiaty, Noviyanti &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Faculty of Pharmacy, University of Pancasila, Jakarta, INDONESIA.&lt;/p&gt;</style></auth-address></record></records></xml>