<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Janhavi Jatin Damani</style></author><author><style face="normal" font="default" size="100%">Radiya Pacha-Gupta</style></author><author><style face="normal" font="default" size="100%">Nandita Mangalore</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Maltase Inhibitory Activity of Aqueous Extracts of Zingiber officinale Rosc. and Trigonella foenum-graecum Linn.</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acarbose</style></keyword><keyword><style  face="normal" font="default" size="100%">Antidiabetic Plants</style></keyword><keyword><style  face="normal" font="default" size="100%">Maltase Inhibitory Activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Trigonella foenum-graecum</style></keyword><keyword><style  face="normal" font="default" size="100%">Zingiber officinale</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/469</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">226-229</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Context:&lt;/strong&gt; An important approach to diabetes treatment involves the regulation of postprandial hyperglycemia by delaying the release of glucose into the bloodstream using inhibitors for carbohydrate digesting enzymes such as maltase. Current synthetic antidiabetic drugs are associated with side effects that have restricted their usage. Antidiabetic plants such as &lt;em&gt;Zingiber officinale&lt;/em&gt; and &lt;em&gt;Trigonella foenum-graecum&lt;/em&gt;, commonly used as medicinal herbs in India, provide an attractive alternative as a source of maltase inhibitors. &lt;strong&gt;Aim:&lt;/strong&gt; This study aimed to determine maltase inhibitory activity in antidiabetic plants in comparison with that of a synthetic drug, Acarbose, used as a positive control. &lt;strong&gt;Study Design:&lt;/strong&gt; &lt;em&gt;In vitro&lt;/em&gt; Enzyme Inhibition Assay. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Aqueous plant extracts were prepared using rhizome of &lt;em&gt;Z. officinale&lt;/em&gt; and leaves of &lt;em&gt;T. foenum-graecum&lt;/em&gt;. Varying concentrations of the aqueous plant extract were tested for maltase inhibitory activity using crude yeast maltase enzyme. &lt;strong&gt;Statistical Analysis:&lt;/strong&gt; Unpaired, two tailed &lt;em&gt;t&lt;/em&gt;-test was used to detect the significant difference between the mean maltase enzyme activity of the control and that of the test. &lt;strong&gt;Results:&lt;/strong&gt; The aqueous extract of &lt;em&gt;T. foenum-graecum&lt;/em&gt; exhibited a higher potent maltase inhibitory activity with IC&lt;sub&gt;50&lt;/sub&gt; value of 1.05% as compared to that of the aqueous extract of &lt;em&gt;Z. officinale&lt;/em&gt; with IC&lt;sub&gt;50&lt;/sub&gt; value of 2.13%. Acarbose showed the highest potency of maltase inhibition with an IC&lt;sub&gt;50&lt;/sub&gt; value of 0.014%. &lt;strong&gt;Conclusion:&lt;/strong&gt; &lt;em&gt;Z. officinale&lt;/em&gt; and &lt;em&gt;T. foenum-graecum&lt;/em&gt; have significant maltase inhibitory activity (&lt;em&gt;p&lt;/em&gt; &amp;lt;0.05). Thus, a contributing factor to the antidiabetic property of the two plants may be attributed to their maltase inhibitory activity.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">226</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Janhavi Jatin Damani, Radiya Pacha-Gupta, Nandita Mangalore &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Life Science and Biochemistry, St. Xavier&amp;rsquo;s College, Mumbai - 400001, Maharashtra, INDIA.&lt;/p&gt;</style></auth-address></record></records></xml>