<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Manish Kumar</style></author><author><style face="normal" font="default" size="100%">Ankita Misra</style></author><author><style face="normal" font="default" size="100%">Akanksha Srivastava</style></author><author><style face="normal" font="default" size="100%">Pushpendra Kumar Shukla</style></author><author><style face="normal" font="default" size="100%">L M Tewari</style></author><author><style face="normal" font="default" size="100%">Sharad Srivastava</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Comparative Pharmacognostical and Pharmacological Evaluation of Costus speciosus (Koen) J.E. Sm. Germplasm Collected from Eastern Ghats of India</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-diabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-inflammatory</style></keyword><keyword><style  face="normal" font="default" size="100%">Costus speciosus</style></keyword><keyword><style  face="normal" font="default" size="100%">Diosgenin</style></keyword><keyword><style  face="normal" font="default" size="100%">HPTLC</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February  2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">150-156</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;Costus speciosus &lt;/em&gt;is an erect perennial herb belonging to family Costaceae, an important medicinal plant widely used in several indigenous medicinal formulations. &lt;strong&gt;Objective: &lt;/strong&gt;A comparative evaluation of Pharmacognostical and Pharmacological potential of &lt;em&gt;Costus speciosus &lt;/em&gt;for the validation of traditional claims and quality parameters for industry. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Pharmacognostical studies were performed as per Ayurvedic Pharmacopeia of India and quantification of diosgenin was done through HPTLC. &lt;em&gt;In vitro&lt;/em&gt; antidiabetic activity was evaluated by α-amylase inhibition assay based on starch iodine method and &lt;em&gt;in vitro &lt;/em&gt;anti-inflammatory were done by using inhibition of protein denaturation assay. &lt;strong&gt;Results: &lt;/strong&gt;The pharmacognostical standards were also laid down for each sample. Morpho-anatomical characters had no distinct variation in all the collected samples of Eastern Ghats. The quantification of diosgenin (without hydrolysis of samples) in the collected germplasm varies significantly from 0.002 to 0.076 % on dry weight basis. The maximum content was recorded in NBCS-06 from Patiya, Bhubaneswar and was identified as distinct chemotype with high metabolite content. IC&lt;sub&gt;50&lt;/sub&gt; value of&lt;em&gt; Costus speciosus &lt;/em&gt;extract in starch-iodine assay was found to be maximum in NBCS- 6 (87.54 μg/ml) and inhibition of protein denaturation assay was found to be maximum in NBCS- 11 (73.91 μg/ml), respectively. &lt;strong&gt;Conclusion: &lt;/strong&gt;The study suggests that the &lt;em&gt;Costus speciosus&lt;/em&gt; germplasm possess potential anti-inflammatory and anti-diabetic activity and comparative pharmacognostical parameters will be useful in collection of location specific potential samples for industrial usage along with quality control of raw materials.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">150</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Manish Kumar&lt;sup&gt;1,2&lt;/sup&gt;, Ankita Misra&lt;sup&gt;1&lt;/sup&gt;, Akanksha Srivastava&lt;sup&gt;1&lt;/sup&gt;, Pushpendra Kumar Shukla&lt;sup&gt;1&lt;/sup&gt;, L. M. Tewari&lt;sup&gt;2&lt;/sup&gt;, Sharad Srivastava&lt;sup&gt;1,&lt;/sup&gt;*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Pharmacognosy Division, CSIR-National Botanical Research Institute, Lucknow (U.P.) 226001, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Botany, D.S.B. Campus, Kumaun University, Nainital-263002, Uttarakhand, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Akanksha Srivastava</style></author><author><style face="normal" font="default" size="100%">Kuldeep Awasthi</style></author><author><style face="normal" font="default" size="100%">Bhanu Kumar</style></author><author><style face="normal" font="default" size="100%">Ankita Misra</style></author><author><style face="normal" font="default" size="100%">Sharad Srivastava</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pharmacognostic and Pharmacological Evaluation of Hyssopus officinalis L. (Lamiaceae) Collected from Kashmir Himalayas, India</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">DPPH</style></keyword><keyword><style  face="normal" font="default" size="100%">HPTLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Hyssopus officinalis</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenolic acids</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/652</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">690-693</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; &lt;em&gt;Hyssopus officinalis&lt;/em&gt; L. is a well-known herb for its culinary and medicinal significance. The purpose of this study was to perform the pharmacognostic evaluation. &lt;strong&gt;Methods:&lt;/strong&gt; Physicochemical and phytochemical analysis, HPTLC quantification and &lt;em&gt;in vitro&lt;/em&gt; antioxidant and antidiabetic activity were done. Results: Preliminary screening revealed the presence of phytomolecules such as alkaloid (0.99%), tannin (1.75%), sugar (1.96%) and starch (0.68%). Total phenolic and flavonoid content were found to be 2.32% and 1.16% respectively. HPTLC quantification data showed that the content of ferulic acid (0.034%) was higher than caffeic acid (0.0064%) on dry weight basis The IC&lt;sub&gt;50&lt;/sub&gt; value for the &lt;em&gt;in vitro&lt;/em&gt; DPPH radical scavenging assay was 0.50 &amp;mu;g/ml and &lt;em&gt;in vitro&lt;/em&gt; anti diabetic assay displayed IC50 value of 0.8366 mg/ml. &lt;strong&gt;Conclusion:&lt;/strong&gt; The study suggests presence of considerable amount of phenolic acids and antioxidant activity in the plant which supports its use in the traditional systems of medicine.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">690</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Akanksha Srivastava, Kuldeep Awasthi, Bhanu Kumar, Ankita Misra, Sharad Srivastava&lt;/strong&gt;&lt;sup&gt;&lt;strong&gt;*&lt;/strong&gt; &lt;/sup&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Pharmacognosy and Ethnopharmacology Division CSIR-National Botanical Research Institute, Lucknow, Uttar Pradesh, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ankita Misra</style></author><author><style face="normal" font="default" size="100%">Akanksha Srivastava</style></author><author><style face="normal" font="default" size="100%">Mohammad Khalid</style></author><author><style face="normal" font="default" size="100%">Poonam Kushwaha</style></author><author><style face="normal" font="default" size="100%">Sharad Srivastava</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Evaluation of Anti Arthritic Potential of Gloriosa superba (L.) Elite Germplasm Collected from Eastern Himalayas, India</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti arthritic</style></keyword><keyword><style  face="normal" font="default" size="100%">Colchicine</style></keyword><keyword><style  face="normal" font="default" size="100%">Elite chemotype</style></keyword><keyword><style  face="normal" font="default" size="100%">G. superba</style></keyword><keyword><style  face="normal" font="default" size="100%">HPTLC</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/387</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">s87-s92</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; &lt;em&gt;Gloriosa superba&lt;/em&gt; (L.) is a traditionally known medicinal plant for its potential antigout property. The species is rich source of colchicine alkaloid and is commercially exploit in the international market for the same. &lt;strong&gt;Method:&lt;/strong&gt; In the present study, elite chemotype of &lt;em&gt;G. superba&lt;/em&gt; was identified from natural population in Eastern Himalayas based on their colchicine content through HPTLC calibrated method. The selected elite chemotypes were further evaluated for &lt;em&gt;in vitro&lt;/em&gt; anti-arthritic potential via inhibition of protein denaturation along with hydroxyl radical scavenging potential. &lt;strong&gt;Result:&lt;/strong&gt; The HPTLC quantification data reveals that the content of colchicine varies from 0.044 to 0.184% having maximum content in NBG-128 from Jorhat, Assam. The results of bioassay reflect a potentiating anti-arthritic and hydroxyl radical scavenging with statistically insignificant difference within the elite germplasms. &lt;strong&gt;Conclusion:&lt;/strong&gt; The presence of bioactive polyphenolics with significant hydroxyl radical scavenging will further suggest that inhibition of inflammatory mediator cells by extract is superimposed action of colchicine and other chemical inhibitors like polyphenolics. The study will aid in site specific exploration of high metabolite yielding chemotype(s) with validated pharmacological action for commercial cultivation to meet out the industrial demand of colchicine and herbal product development.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">s87</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ankita Misra&lt;sup&gt;1,2,&lt;/sup&gt; Akanksha Srivastava&lt;sup&gt;1&lt;/sup&gt;, Mohammad Khalid&lt;sup&gt;2&lt;/sup&gt;, Poonam Kushwaha&lt;sup&gt;2&lt;/sup&gt;, Sharad Srivastava&lt;sup&gt;1&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Pharmacognosy and Ethnopharmacology Division, CSIR-National Botanical Research Institute, Lucknow, Uttar Pradesh 226001, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh 226001, INDIA.&amp;nbsp;&lt;/p&gt;</style></auth-address></record></records></xml>