<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Fitri Santy Budiarso</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Muhammad Hanafi</style></author><author><style face="normal" font="default" size="100%">Roshamur Cahyan Forestrania</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Potential of Stem Bark of Kayu Sarampa (Xylocarpus moluccensis (Lam.) M. Roen)) as α-glucosidase Inhibitor</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alpha-glucosidase inhibitor</style></keyword><keyword><style  face="normal" font="default" size="100%">Antidiabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Kayu Sarampa</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1368-1376</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; The prevalence of diabetes mellitus type 2 in the world is more than 230 million people, increases about 3% in a year. Kayu Sarampa or Nyirih batu (&lt;em&gt;Xylocarpus moluccensis&lt;/em&gt; (Lam.) M. Roen) has traditionally been used to treat diabetic patient by native people in Ratahan, North Celebes, Indonesia. Therefore, this research was sequentially extracted bioactive component from stem bark of kayu sarampa showed alpha glucosidase inhibitor. &lt;strong&gt;Objective:&lt;/strong&gt; To assess antioxidants and alpha glucosidase inhibitory activity of hexane, ethyl acetate, and methanol extract from stem bark of Kayu Sarampa. &lt;strong&gt;Method:&lt;/strong&gt; The Stem bark was extracted with Reflux method using hexane, ethyl acetate, and methanol as mobile phae/solvent. The Hexane Extract (HE), Ethyl Acetic Extract (EAE) and Methanol Extract (ME) were subjected to the antioxidant activity assay by the 2.2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and the ferric-reducing antioxidant power (FRAP) method. Antidiabetic activity was determined by enzymatic alpha-glucosidase inhibitor. &lt;strong&gt;Results:&lt;/strong&gt; The extract which had the highest activity based on the DPPH test and FRAP test was the ME compared with EAE, and HE with IC50 values of 16.51 μg/mL, 34.10 51 μg/mL, and 38.82 51 μg/mL , respectively. Ferrous equivalent antioxidant capacity (FeEAC) method, methanolic extract had a higher reduction capacity than the EH and EEA which were 148.96 μmol/gr, 48.96 μmol/gr, and 148.96 μmol/gr, respectively. The result showed that kayu sarampa stem bark exhibited antidiabetic activity due to its high inhibition compared with control (acarbose). ME showed inhibition of 53,11% followed with EAE 49,7%, HE 44,53%, and acarbose as control 29,32%.Conclusion: stem bark of kayu sarampa have bioactive component as alpha glucosidase inhibitor&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1368</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Fitri Santy Budiarso&lt;sup&gt;1&lt;/sup&gt;, Berna Elya&lt;sup&gt;1,&lt;/sup&gt;*, Muhammad Hanafi&lt;sup&gt;2&lt;/sup&gt;, Roshamur Cahyan Forestrania&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, Universitas Indonesia, Kampus UI Depok, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Indonesian Institute of Sciences and Faculty of Pharmacy, University of Pancasila, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Basah Katrin</style></author><author><style face="normal" font="default" size="100%">Roshamur Cahyan Forestrania</style></author><author><style face="normal" font="default" size="100%">Rosmalena Sofyan</style></author><author><style face="normal" font="default" size="100%">Ryan Adi Chandra</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Alkaloid from Phoebe declinata Nees Leaves</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alkaloid</style></keyword><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Cytotoxic activity</style></keyword><keyword><style  face="normal" font="default" size="100%">DPPH</style></keyword><keyword><style  face="normal" font="default" size="100%">MCF-7 cell line.</style></keyword><keyword><style  face="normal" font="default" size="100%">Phoebe declinata nees</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/165</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">713-720</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Genus Phoebe have been reported to produce isoquinoline alkaloids as aporphines, noraporphines, and benzylisoquinolines. Many of these isolates exhibit diversified biological activities, including cytotoxic activity. &lt;strong&gt;Objective:&lt;/strong&gt; The objective of this study is to determine cytotoxic activity of compound isolated from &lt;em&gt;Phoebe declinata&lt;/em&gt; againts MCF-7 (breast cancer cell line). &lt;strong&gt;Methods:&lt;/strong&gt; Extraction was done by reflux using n-hexane, antioxidant activity measured by DPPH method and reducing power method, cytotoxic activity measured by MTT assay using MCF-7 cell line, struture eucidation was confirmed by NMR. &lt;strong&gt;Results:&lt;/strong&gt; The antioxidant activity measured using DPPH method for 1 and 2 showed IC&lt;sub&gt;50&lt;/sub&gt; value of 6.42 and 11.80 &amp;mu;g/mL respectively and using reducing power method for 1 and 2 showed IC&lt;sub&gt;50&lt;/sub&gt; value of 7.02 and 13.74 &amp;mu;g/mL respectively. Compound (1) and (2) exhibited cytotoxic activity against MCF-7 cells with an IC&lt;sub&gt;50&lt;/sub&gt; value of 82.978 and 93.179 &amp;mu;g/mL. &lt;strong&gt;Conclusion:&lt;/strong&gt; Compound (1) and (2) exhibited antioxidant activity and cytotoxic activity against MCF-7.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">713</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Berna Elya&lt;sup&gt;1,2*&lt;/sup&gt;, Basah Katrin&lt;sup&gt;1&lt;/sup&gt;, Roshamur Cahyan Forestrania&lt;sup&gt;1&lt;/sup&gt;, Rosmalena Sofyan&lt;sup&gt;3,&amp;nbsp;&lt;/sup&gt;Ryan Adi Chandra&lt;sup&gt;3&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, University of Indonesia, Kampus UI Depok,16424.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Center of Study on Natural Products, University of Indonesia, Kampus UI Depok,16424.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Faculty of Medicine, University of Indonesia, Kampus UI depok, 16424.&lt;/p&gt;</style></auth-address></record></records></xml>