<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Regiane Sablina Almeida Bernardes</style></author><author><style face="normal" font="default" size="100%">Sandra Layse Ferreira Sarrazin</style></author><author><style face="normal" font="default" size="100%">Flaviana Alves dos Santos</style></author><author><style face="normal" font="default" size="100%">Moacyr Jesus Barreto de Melo Rêgo</style></author><author><style face="normal" font="default" size="100%">Maira Galdino da Rocha Pitta</style></author><author><style face="normal" font="default" size="100%">Marina Ferraz Cordeiro</style></author><author><style face="normal" font="default" size="100%">Patrícia Danielle Oliveira de Almeida</style></author><author><style face="normal" font="default" size="100%">Ricardo Bezerra de Oliveira</style></author><author><style face="normal" font="default" size="100%">Leoneide Érica Maduro Bouillet</style></author><author><style face="normal" font="default" size="100%">José Guilherme Soares Maia</style></author><author><style face="normal" font="default" size="100%">Rosa Helena Veras Mourão</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant Capacity and Cytotoxicity of the Aqueous Extract of Myrcia guianensis (Aubl.) DC</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Myrtaceae</style></keyword><keyword><style  face="normal" font="default" size="100%">Oxidative stress</style></keyword><keyword><style  face="normal" font="default" size="100%">Pedra-ume-caá</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenolic compounds</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">s135-s140</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Ethnobotanical studies report that &lt;em&gt;Myrcia guianensis&lt;/em&gt; (Myrtaceae), belonging to a group of plants known as pedr&amp;aacute;-ume-ca&amp;aacute; or insulin plant, is used as a tea to treat various diseases, including diabetes, a metabolic disorder that leads to the constant production of free radicals. The objective of this work was to determine the antioxidant capacity and the cytotoxicity of the AEMg. &lt;strong&gt;Methods:&lt;/strong&gt; The content of phenolic compounds in AEMg was determined by colorimetric assays. &lt;em&gt;In vitro&lt;/em&gt; tests of the antioxidant capacity of AEMg, in the sequestration of DPPH radicals, in &amp;beta;-carotene bleaching, in the FRAP, as well as in human fibroblast cells of the MRC-5 lineage, were performed. The cytotoxic activity of AEMg was evaluated in assays with eukaryotic cells from yeast &lt;em&gt;Saccharomyces cerevisiae&lt;/em&gt; and in PBMC. &lt;strong&gt;Results:&lt;/strong&gt; The results showed that the AEMg is rich in phenolic compounds, presenting high antioxidant potential in all the tests carried out, including in human fibroblast cells of the MRC-5 lineage, besides not being toxic to eukaryotic cells. &lt;strong&gt;Conclusion&lt;/strong&gt;: The AEMg, rich in antioxidant compounds and no toxicity, can be used as source of natural antioxidant in the treatment of metabolic diseases to combat free radicals.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">s135</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Regiane Sablina Almeida Bernardes&lt;sup&gt;1,2&lt;/sup&gt;, Sandra Layse Ferreira Sarrazin&lt;sup&gt;2&lt;/sup&gt;, Flaviana Alves dos Santos&lt;sup&gt;4&lt;/sup&gt;, Moacyr Jesus Barreto de Melo R&amp;ecirc;go&lt;sup&gt;4&lt;/sup&gt;, Maira Galdino da Rocha Pitta&lt;sup&gt;4&lt;/sup&gt;, Marina Ferraz Cordeiro&lt;sup&gt;5&lt;/sup&gt;, Patr&amp;iacute;cia Danielle Oliveira de Almeida&lt;sup&gt;6&lt;/sup&gt;, Ricardo Bezerra de Oliveira&lt;sup&gt;2&lt;/sup&gt;, Leoneide &amp;Eacute;rica Maduro Bouillet&lt;sup&gt;2&lt;/sup&gt;, Jos&amp;eacute; Guilherme Soares Maia&lt;sup&gt;3&lt;/sup&gt;, Rosa Helena Veras Mour&amp;atilde;o&lt;sup&gt;1,2,3*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Programa de P&amp;oacute;s-Gradua&amp;ccedil;&amp;atilde;o em Biodiversidade e Biotecnologia da Amaz&amp;ocirc;nia Legal (Bionorte), Universidade Federal do Amazonas, 60077-000 Manaus, AM, BRAZIL.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt; 2&lt;/sup&gt;Laborat&amp;oacute;rio de Bioprospec&amp;ccedil;&amp;atilde;o e Biologia Experimental, Universidade Federal do Oeste do Par&amp;aacute;, 68135-110 Santar&amp;eacute;m, PA, BRAZIL.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Programa de P&amp;oacute;s-Gradua&amp;ccedil;&amp;atilde;o em Recursos Naturais da Amaz&amp;ocirc;nia, Universidade Federal do Oeste do Par&amp;aacute;, 68135-110 Santar&amp;eacute;m, PA, BRAZIL.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt; 4&lt;/sup&gt;N&amp;uacute;cleo de Pesquisa para Inova&amp;ccedil;&amp;atilde;o Terap&amp;ecirc;utica Suely Galdino, Universidade Federal de Pernambuco, 50670- 901 Recife, PE, BRAZIL.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Universidade Federal do Vale do S&amp;atilde;o Francisco, Colegiado de Medicina, Campus Paulo Afonso, 48607-190, BA, BRAZIL.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Universidade Federal do Amazonas, Laborat&amp;oacute;rio de Atividade Biol&amp;oacute;gica, 60077-000 Manaus, AM, BRAZIL.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ramdan Btissam</style></author><author><style face="normal" font="default" size="100%">El Malki Fatima</style></author><author><style face="normal" font="default" size="100%">Eddarraji Kamal</style></author><author><style face="normal" font="default" size="100%">Greche Hassane</style></author><author><style face="normal" font="default" size="100%">NHIRI Mohamed</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Composition and Antibacterial Activity of Hydro-Alcohol and Aqueous Extracts Obtained from the Lamiaceae Family</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Aqueous Extract.</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoic Content</style></keyword><keyword><style  face="normal" font="default" size="100%">Hydro-Alcohol Extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Lamiaceae Family</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenolic compounds</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/402</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">81-91</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Context:&lt;/strong&gt; Plant from the &lt;em&gt;Lamiaceae&lt;/em&gt; family are considered as dietary spices and medicinal herbs traditionally used in medicine for the treatment of several pathologies. &lt;strong&gt;Objective:&lt;/strong&gt; Evaluation of the &lt;em&gt;in vitro&lt;/em&gt; antibacterial activity of ethanol and aqueous extracts of nine Moroccan plants from the Lamiaceae family against six bacterial strains regularly implicated in toxiinfection. &lt;strong&gt;Method:&lt;/strong&gt; The antibacterial activities of hot (HAE), cold (CAE) aqueous extracts and ethanolic extracts (EE) were evaluated using agar-well diffusion method, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and IC&lt;sub&gt;50&lt;/sub&gt; against six foodborne bacteria (&lt;em&gt;Bacillus cereus, Listeria monocytogenes, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa&lt;/em&gt; and &lt;em&gt;Salmonella enterica&lt;/em&gt;). Total phenolic and flavonoid contents were assessed as well. &lt;strong&gt;Results:&lt;/strong&gt; In the present study, the ethanol extracts were rich in polyphenols, with middling values of flavonoids, and relatively poor in condensed tannins. The presence of saponins, essential oils, irroides, alkaloids, anthocyanins, and aldehydes was recorded. The effect of the extracts was directly bactericidal for &lt;em&gt;B. cereus&lt;/em&gt; and &lt;em&gt;L. monocytogenes&lt;/em&gt;; for the other strains, the MBC value was twice higher than that of MIC. However, the ethanol extract (EE) of &lt;em&gt;O. majorana&lt;/em&gt; and &lt;em&gt;T. satureioides &lt;/em&gt;showed the highest antibacterial activity. With the principal component analysis, it was demonstrated that the nine &lt;em&gt;Lamiaceae&lt;/em&gt; family plants possess a powerful antibacterial effect, correlated with their phenolic content. &lt;strong&gt;Statistical analysis:&lt;/strong&gt; Analysis of variance was performed by uni-varied ANOVA in the software SPSS 22 Fr. &lt;strong&gt;Conclusion:&lt;/strong&gt; The active compounds were thermostable and soluble in ethanol and water. The antimicrobial activities of the plants extracts investigated may contribute to understand their involvement in traditional medicine against many microbial infections.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">81</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Ramdan Btissam&lt;sup&gt;1&lt;/sup&gt;, El Malki Fatima&lt;sup&gt;2&lt;/sup&gt;, Eddarraji Kamal&lt;sup&gt;1,2&lt;/sup&gt;, Greche Hassane&lt;sup&gt;3&lt;/sup&gt; and Nhiri Mohamed&lt;sup&gt;1&lt;/sup&gt;*&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;sup&gt; 1&lt;/sup&gt;Department of Biology, Laboratory of Biochemistry and Molecular Genetics, Faculty of Science and Technology, University Abdelmalek Essaadi, BP 416, Tangier 90000, MOROCCO.&lt;/p&gt;
&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratory of Microbiology, Department of Hygiene and Food Safety, Pasteur Institute of Morocco, Tangier 90000, MOROCCO.&lt;/p&gt;
&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;National Institute of Medicinal and Aromatic Plants, University of Sidi Mohamed Ben Abdellah, BP 8857, 30100 Atlas, Fes, MOROCCO.&lt;/p&gt;</style></auth-address></record></records></xml>