<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Janani Jacob</style></author><author><style face="normal" font="default" size="100%">Gopalan R</style></author><author><style face="normal" font="default" size="100%">Lakshmanaperumalsamy P</style></author><author><style face="normal" font="default" size="100%">Ramanaiah Illuri</style></author><author><style face="normal" font="default" size="100%">Damaji Bhosle</style></author><author><style face="normal" font="default" size="100%">Gopala Krishna Sangli</style></author><author><style face="normal" font="default" size="100%">Deepak Mundkinajeddu</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Evaluation of Anti-psoriatic Potential of the Fruit Rind of Punica granatum L.</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-psoriatic activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Punica granatum</style></keyword><keyword><style  face="normal" font="default" size="100%">Thymidine phosphorylase inhibition</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">466-468</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Pomegranate (&lt;em&gt;Punica granatum L.&lt;/em&gt;) is universally known for its therapeutic properties due to its potential bioactive compounds. However, there is no established scientific study on antipsoriatic activity of pomegranate fruit rind. The aim of the study is to evaluate the anti-psoriatic activity of the isolated compounds and the extract from the fruit rind of &lt;em&gt;P. granatum.&lt;/em&gt; In our previous study, the isolated compounds were evaluated for antioxidant potential. In continuation to the previous investigation, the present study is taken up to evaluate the extract and compounds for &lt;em&gt;in vitro&lt;/em&gt; anti-psoriatic activity. &lt;strong&gt;Methods:&lt;/strong&gt; Chromatographic techniques were employed to isolate the compounds from the aqueous acetone extract and&lt;em&gt; in vitro &lt;/em&gt;anti-psoriatic activity was determined by thymidine phosphorylase inhibition assay. &lt;strong&gt;Results: &lt;/strong&gt;From previous phytochemical investigation, three compounds were identified as Punicalagin, 2,3(&lt;em&gt;S&lt;/em&gt;)-hexahydroxydiphenoyl-D-glucose and Punicalin. In the present study, the extract and the compounds were evaluated for anti-psoriatic activity. The results reveal that the isolated three compounds showed inhibitory activity of 89% to 95% against thymidine phosphorylase. Aqueous acetone extract also exhibited 87% inhibition. &lt;strong&gt;Conclusion: &lt;/strong&gt;&lt;em&gt;Punica granatum&lt;/em&gt; is an ideal plant for further investigation to prove its anti-psoriatic activity.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&amp;nbsp;&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">466</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Janani Jacob&lt;sup&gt;1,2*&lt;/sup&gt;, Gopalan R&lt;sup&gt;3&lt;/sup&gt; Lakshmanaperumalsamy P&lt;sup&gt;4&lt;/sup&gt;, Ramanaiah Illuri&lt;sup&gt;2&lt;/sup&gt;, Damaji Bhosle&lt;sup&gt;2&lt;/sup&gt;, Gopala Krishna Sangli&lt;sup&gt;2&lt;/sup&gt;, Deepak M&lt;sup&gt;2&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Research Scholar, Karpagam Academy of Higher Education, Coimbatore- 641021, Tamil Nadu, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;R and&amp;nbsp;D Centre, Natural Remedies Pvt. Ltd. Bangalore-560 100, Karnataka, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Botany, Karpagam Academy of Higher Education, Coimbatore- 641021, Tamil Nadu INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Environmental Sciences, Bharathiar University, Coimbatore- 641 046, Tamil Nadu INDIA.&lt;/p&gt;
</style></auth-address></record></records></xml>