<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Marisca Evalina Gondokesumo</style></author><author><style face="normal" font="default" size="100%">Bambang Pardjianto</style></author><author><style face="normal" font="default" size="100%">Sutiman Bambang Sumitro</style></author><author><style face="normal" font="default" size="100%">Wahyu Widowati</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Xanthones Analysis and Antioxidant Activity Analysis (Applying ESR) of Six Different Maturity Levels of Mangosteen Rind Extract (Garcinia mangostana Linn.)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Electron spin resonance (ESR)</style></keyword><keyword><style  face="normal" font="default" size="100%">Free radical</style></keyword><keyword><style  face="normal" font="default" size="100%">Mangosteen rind extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Xanthone Garcinia mangostana</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">369-373</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;strong&gt;Background:&lt;/strong&gt; Mangosteen (&lt;em&gt;Garcinia mangostana&lt;/em&gt; Linn.) is tropical fruit that known to contain bioactive compounds which has particular function as antioxidants, anti-inflammatory and antibacterial. Mangosteen rind extract is known to have high contents of xanthone compounds which have antioxidant and free radical scavenging activities. This study was aiming to determine the contents of xanthone derivatives using Liquid Chromatography Mass Spectrometry (LC-MS/MS) and antioxidant activity of six different maturity levels of mangosteen rind extract using electron spin resonance (ESR). &lt;strong&gt;Method:&lt;/strong&gt; Mangosteen was classified based on the maturity level by its visual characteristic and divided into six criteria of maturity. The mangosteen rinds were extracted through maceration and freeze drying method. Qualitative analysis of xanthone was obtained using LC-MS/MS. Antioxidant activity was determined using ESR spectrometer. To evaluate antioxidant activity, using 2,2-diphenyl-1-picrylhydrazyl (DPPH) was used as free radical scavenger method. &lt;strong&gt;Results:&lt;/strong&gt; The LC-MS/MS analysis showed that the highest concentrations are filled by mangosteen rind with maturity level 6. Moreover, each maturity levels of mangosteen rind extract has different g value compared to DPPH free radical. Different g value indicated the different type of free radical and decreasing g value indicated the declining intensity of free radical. The higher decreasing of g value was mangosteen rind with maturity level 4, 5 and 6. &lt;strong&gt;Conclusion:&lt;/strong&gt; Mangosteen rind extract contains xanthone and its derivatives and ESR analysis showed that different maturity levels on mangosteen rind has different antioxidant activity as indicated by declining free radical intensity.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">369</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Marisca Evalina Gondokesumo&lt;sup&gt;1,2,*&lt;/sup&gt;, Bambang Pardjianto&lt;sup&gt;3&lt;/sup&gt;, Sutiman Bambang Sumitro&lt;sup&gt;4&lt;/sup&gt;, Wahyu Widowati&lt;sup&gt;5&lt;/sup&gt;, Kusworini Handono&lt;sup&gt;6 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Medicine, Biomedical Sciences Doctoral Study Program, Brawijaya University, Malang, East Java, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Pharmacy, University of Surabaya, Surabaya, East Java, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Plastic Surgery, Saiful Anwar General Hospital, Faculty of Medicine, Brawijaya University, Malang, East Java, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, Malang, East Java, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;5&lt;/sup&gt;Faculty of Medicine, Maranatha University, Bandung, West Java, INDONESIA. 6Department of Clinical Pathology, Faculty of Medicine, Brawijaya University, Malang, East Java, INDONESIA.&lt;/p&gt;
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