<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sarah Zielda Najib</style></author><author><style face="normal" font="default" size="100%">Wilzar Fachri</style></author><author><style face="normal" font="default" size="100%">Rani Sauriasari</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Raymond Tjandrawinata</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Cholesterol-lowering Effects of Extract from Garcinia daedalanthera in Hyperlipidemic rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-cholesterol</style></keyword><keyword><style  face="normal" font="default" size="100%">Garcinia</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbal</style></keyword><keyword><style  face="normal" font="default" size="100%">In vivo</style></keyword><keyword><style  face="normal" font="default" size="100%">Pre-clinical study</style></keyword><keyword><style  face="normal" font="default" size="100%">Rat</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">1125-1128</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; A native plant from Indonesia, &lt;em&gt;Garcinia daedalanthera&lt;/em&gt; has been scientifically proven have antidiabetic effects and antioxidant activity. We hypothesized that &lt;em&gt;Garcinia daedalanthera&lt;/em&gt; can modulate the lipid profiles of hyperlipidemic rats. &lt;strong&gt;Objective:&lt;/strong&gt; This study aimed to evaluate the antihyperlipidemic potential of &lt;em&gt;Garcinia daedalanthera&lt;/em&gt; extract. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; &lt;em&gt;Garcinia daedalanthera&lt;/em&gt; leaves extract (GDE) were orally administrated to high fat diet-induced rats for 15 days. After the end of experimental period (43 days) the lipid profiles were estimated along with histopathological liver examination of animals. &lt;strong&gt;Results:&lt;/strong&gt; The results showed that &lt;em&gt;Garcinia daedalanthera&lt;/em&gt; extract significantly reduced the level of serum total cholesterol, total triglycerides and low-density lipoprotein as compared to control group with an increasing level of serum high-density lipoprotein. Furthermore, the extract has a favorable effect on histopathological study. &lt;strong&gt;Conclusion:&lt;/strong&gt; This study proved antilipidemic property by lowering altered levels of lipid profile in male wistar rats and suggest lipid lowering effects of &lt;em&gt;Garcinia daedalanthera&lt;/em&gt; extract which serves as a new potential natural product for preventing hyperlipidemia.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1125</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Sarah Zielda Najib&lt;sup&gt;1&lt;/sup&gt;,&amp;nbsp;Wilzar Fachri&lt;sup&gt;2&lt;/sup&gt;,&amp;nbsp;Rani Sauriasari&lt;sup&gt;1&lt;/sup&gt;*,&amp;nbsp;Berna Elya&lt;sup&gt;1&lt;/sup&gt;, Raymond Tjandrawinata&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, University of Indonesia, Depok, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Medicine, University of Indonesia, Salemba, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Dexa Laboratories of Biomolecular Sciences, Cikarang, INDONESIA.&lt;/p&gt;</style></auth-address></record></records></xml>